Decreased expression of the mitochondrial BCAT protein correlates with improved patient survival in IDH-WT gliomas
(2016)
Journal Article
Ellis, H. P., Williams, M., Hull, J., Conway, M. E., Hull, J., El Hindy, M., …Kurian, K. M. (2016). Decreased expression of the mitochondrial BCAT protein correlates with improved patient survival in IDH-WT gliomas. Brain Pathology, 26(6), 789-791. https://doi.org/10.1111/bpa.12385
Background and research question: Gliomas represent 43% of all solid intracranial tumours, of which glioblastomas have the poorest prognosis. Recently, the human cytosolic branched-chain aminotransferase protein (hBCATc), which metabolises the branch... Read More about Decreased expression of the mitochondrial BCAT protein correlates with improved patient survival in IDH-WT gliomas.