All Outputs (135)

Influence of sildenafil on the purinergic components of nerve-mediated and urothelial ATP release from the bladder of normal and spinal cord injured mice (2019)
Journal Article

© 2019 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society. Background and purpose: PDE inhibitors such as sildenafil alleviate lower urinary tract symptoms; however, a comple... Read More about Influence of sildenafil on the purinergic components of nerve-mediated and urothelial ATP release from the bladder of normal and spinal cord injured mice.

From fast identification to resistance testing: Volatile compound profiling as a novel diagnostic tool for detection of antibiotic susceptibility (2019)
Journal Article

Widespread use of antibiotics has led to the development of antibiotic resistance in many pathogenic bacteria. If effective methods of alleviating this crisis are not applied, a return to high mortality and morbidity of the pre-antibiotic era could o... Read More about From fast identification to resistance testing: Volatile compound profiling as a novel diagnostic tool for detection of antibiotic susceptibility.

Virulence of a T6SS Campylobacter jejuni chicken isolate from North Romania (2019)
Journal Article

Objectives: In this study we have investigated the in vitro and in vivo virulence characteristics of a new T6SS positive Campylobacter jejuni chicken isolate (SV12) originating from a poultry population in North Romania. A detailed phenotypic charact... Read More about Virulence of a T6SS Campylobacter jejuni chicken isolate from North Romania.

Evaluation of Two Sigma TranswabⓇ Systems for maintenance of viability of pathogenic Candida spp. using the clinical and laboratory standards institute M40-A2 standard (2019)
Presentation / Conference Contribution

Expression and localization of aquaporin water channels in adult pig urinary bladder (2019)
Journal Article

N/A

Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment (2019)
Journal Article

© 2019 Clayton, Thorn and Reynolds. Point-of-use (POU) drinking water treatment systems provide solutions for communities where centralized facilities are unavailable. Effective POU systems treat and reduce the number of pathogens in POU water suppl... Read More about Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment.

What influences adherence to treatment in people with multiple sclerosis? (2019)
Thesis

Background
Currently, there are a number of disease modifying therapies (DMTs) available that can help to reduce the number of attacks experienced in relapsing remitting multiple sclerosis (RRMS). However, optimal outcomes are not always achieved du... Read More about What influences adherence to treatment in people with multiple sclerosis?.

An in vitro biofilm model of Staphylococcus aureus infection of bone (2019)
Journal Article

Chronic osteomyelitis is difficult to treat, with biofilm growth and the diffusion barrier to antibiotics presented by bone contributory factors. The aim of this study was to develop and evaluate an invitro model of osteomyelitis. A bioluminescent st... Read More about An in vitro biofilm model of Staphylococcus aureus infection of bone.

BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells (2019)
Journal Article

To decrease bowel cancer incidence and improve survival, we need to understand the mechanisms that drive tumorigenesis. Recently B-cell lymphoma 3 (BCL-3; a key regulator of NF-κB signalling) has been recognised as an important oncogenic player in so... Read More about BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells.

Hydrophilic interaction liquid chromatography: An update (2019)
Journal Article

This article is an update on the technique of hydrophilic interaction liquid chromatography (HILIC) and covers recent ideas on the mechanism of separation, and how it may be manipulated to suit the separation of particular sample types. The advantage... Read More about Hydrophilic interaction liquid chromatography: An update.

Selective reduction of APP-BACE1 activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PDAPP mice (2019)
Journal Article

β-Amyloid (Aβ) accumulation is an early event of Alzheimer's disease (AD) pathogenesis. Inhibition of Aβ production by β-secretase (BACE) has been proposed as a potential therapeutic strategy for AD. However, BACE inhibitors lack specificity and have... Read More about Selective reduction of APP-BACE1 activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PDAPP mice.

Pseudomonas syringae: Enterprising epiphyte and stealthy parasite (2019)
Journal Article

© 2019 The Authors. Pseudomonas syringae is best known as a plant pathogenic bacterium that causes diseases in a multitude of hosts, and it has been used as a model organism to understand the biology of plant disease. Pathogenic and non-pathogenic is... Read More about Pseudomonas syringae: Enterprising epiphyte and stealthy parasite.

Protein SUMOylation regulates insulin secretion at multiple stages (2019)
Journal Article

Type-II Diabetes Mellitus (T2DM) is one of the fastest growing public health issues of modern times, consuming 12% of worldwide health budgets and affecting an estimated 400 million people. A key pathological trait associated with this disease is the... Read More about Protein SUMOylation regulates insulin secretion at multiple stages.

Considerations of the importance of redox state for reactive nitrogen species action (2019)
Journal Article

Nitric oxide (NO) and other reactive nitrogen species (RNS) are immensely important signalling molecules in plants, being involved in a range of physiological responses. However, the exact way in which NO fits into signal transduction pathways is not... Read More about Considerations of the importance of redox state for reactive nitrogen species action.

Being Black in Academia (2019)
Presentation / Conference Contribution

Thermal and non-thermal processing technologies on intrinsic and extrinsic quality factors of tomato products: A review (2019)
Journal Article

Tomato and tomato-based products play a vital role in human diet due to the presence of bioactive compounds. The conventional heat treatment is designed as a current practice in tomato products industry to ensure food safety but it can lead to undesi... Read More about Thermal and non-thermal processing technologies on intrinsic and extrinsic quality factors of tomato products: A review.

Wnt signaling is a major determinant of neuroblastoma cell lineages (2019)
Journal Article

© 2019 Szemes, Greenhough and Malik. The neural crest (NC), which has been referred to as the fourth germ layer, comprises a multipotent cell population which will specify diverse cells and tissues, including craniofacial cartilage and bones, melanoc... Read More about Wnt signaling is a major determinant of neuroblastoma cell lineages.

Pharmacodynamics of ciprofloxacin against Pseudomonas aeruginosa planktonic and biofilm‐derived cells (2019)
Journal Article

© 2019 The Society for Applied Microbiology The influence of growth phase and state on the survival and recovery of Pseudomonas aeruginosa exposed to ciprofloxacin was investigated using batch culture grown planktonic cells and disaggregated biofilm... Read More about Pharmacodynamics of ciprofloxacin against Pseudomonas aeruginosa planktonic and biofilm‐derived cells.

In what ways could STEM employers create an inclusive working environment for potential BME applicants? (2019)
Presentation / Conference Contribution

Trace voltammetric determination of lead at a recycled battery carbon rod electrode (2019)
Journal Article

Carbon rod electrodes (CREs) were obtained from recycled zinc–carbon batteries and were used without further modification for the measurement of trace concentrations of lead (Pb). The electrochemical behavior of Pb at these electrodes in a variety of... Read More about Trace voltammetric determination of lead at a recycled battery carbon rod electrode.