All Outputs (126)

Fabrication of miniaturised screen-printed glucose biosensors, using a water-based ink, and the evaluation of their electrochemical behaviour (2018)
Journal Article

This paper describes a simple, convenient approach to the fabrication of microband electrodes and microband biosensors based on screen printing technology. These devices were printed in a three-electrode configuration on one strip; a silver/silver ch... Read More about Fabrication of miniaturised screen-printed glucose biosensors, using a water-based ink, and the evaluation of their electrochemical behaviour.

Aggrecanase degradation of type III collagen is associated with clinical knee pain (2018)
Journal Article

There is a lack of biochemical markers for non-invasive and objective assessment of symptomatic osteoarthritis (OA). Aggrecanase activity has been shown to be associated with joint deterioration and symptomatic disease through the degradation of extr... Read More about Aggrecanase degradation of type III collagen is associated with clinical knee pain.

The sequence of two bacteriophages with hypermodified bases reveals novel phage-host interactions (2018)
Journal Article

© 2018 by the authors. Licensee MDPI, Basel, Switzerland. Bacteriophages SP-15 and ΦW-14 are members of the Myoviridae infecting Bacillus subtilis and Delftia (formerly Pseudomonas) acidovorans, respectively. What links them is that in both cases, ap... Read More about The sequence of two bacteriophages with hypermodified bases reveals novel phage-host interactions.

Coping with environmental eukaryotes; identification of pseudomonas syringae genes during the interaction with alternative hosts or predators (2018)
Journal Article

Understanding the molecular mechanisms underpinning the ecological success of plant pathogens is critical to develop strategies for controlling diseases and protecting crops. Recent observations have shown that plant pathogenic bacteria, particularly... Read More about Coping with environmental eukaryotes; identification of pseudomonas syringae genes during the interaction with alternative hosts or predators.

Direct thermal desorption gas chromatographic determination of toxicological relevant concentrations of ethylene glycol in whole blood (2018)
Presentation / Conference Contribution

Ethylene Glycol has been determined directly in whole blood using thermal desorption gas chromatography. Recoveries of between 84.8 % to 107 % were recorded, with corresponding %CV of between 1.7 % and 5.8 %. No extraction or derivatization steps w... Read More about Direct thermal desorption gas chromatographic determination of toxicological relevant concentrations of ethylene glycol in whole blood.

Molecular simulation of self-assembly (2018)
Book Chapter

Molecular simulation is a powerful tool for studying self-assembly, as it can provide unprecedented access into a range of physical properties at the intra-, inter- and supra-molecular scales. The self-assembly of biological molecules, a ubiquitous p... Read More about Molecular simulation of self-assembly.

Location-based metagames for learning (2018)
Presentation / Conference Contribution

Metabolomics and metabolic function analysis of the secretome of articular cartilage and isolated chondrocytes in response to pro-inflammatory cytokines (2018)
Presentation / Conference Contribution

Chondrocytes rely primarily on glycolysis to meet their energy requirements, but possess the metabolic flexibility to support cell survival and matrix synthesis during periods of nutrient stress, by enhancing glycolysis with mitochondrial respiration... Read More about Metabolomics and metabolic function analysis of the secretome of articular cartilage and isolated chondrocytes in response to pro-inflammatory cytokines.

Immunotherapeutic and pharmacological approaches for the treatment of Alzheimer’s disease (2018)
Journal Article

The development of efficacious treatments targeting Alzheimer’s disease (AD) aetiology has been proved an extensive, time consuming task. Currently prescribed therapies, primarily acetylcholinesterase inhibitors such as donepezil and the NMDAreceptor... Read More about Immunotherapeutic and pharmacological approaches for the treatment of Alzheimer’s disease.

Anodic stripping voltammetric determination of zinc at a 3-D printed carbon nanofiber–graphite–polystyrene electrode using a carbon pseudo-reference electrode (2018)
Journal Article

© 2018 Elsevier B.V. The application of a novel fully 3-D printed carbon nanofiber–graphite–polystyrene electrode has been investigated for the trace determination of Zn2+ by differential pulse anodic stripping voltammetry. The possibility of utilisi... Read More about Anodic stripping voltammetric determination of zinc at a 3-D printed carbon nanofiber–graphite–polystyrene electrode using a carbon pseudo-reference electrode.

Developing a community of practice to support the space engineering higher education community (2018)
Presentation / Conference Contribution

The UK-based “Space Universities Network” (SUN) was formed in 2016 with the aim of enhancing the quality of learning and teaching by providing support and resources to the space science and engineering higher education community. The goal of this res... Read More about Developing a community of practice to support the space engineering higher education community.

Influence of occupational physical activity on anthropometric profile and body composition of bricklayers in Kwara state, Nigeria (2018)
Journal Article

Objectives
Optimal amount of muscle and fat mass has been associated with level of physical activity and are basic determinants of individuals’ health, fitness including occupational performance. The study determined the level of occupational physic... Read More about Influence of occupational physical activity on anthropometric profile and body composition of bricklayers in Kwara state, Nigeria.

Interrogating water and public health concerns through participatory theatre methodologies - The Iheakpu-Awka example (2018)
Presentation / Conference Contribution

Health Humanities as an emerging discipline seeks the convergence of health and humanities in the effort to promote good health as well tackle health concerns. Theatre has been identified as a powerful tool of change for preventive medicine. As an ef... Read More about Interrogating water and public health concerns through participatory theatre methodologies - The Iheakpu-Awka example.

A study of column equilibration time in hydrophilic interaction chromatography (2018)
Journal Article

© 2018 Elsevier B.V. The time taken to achieve full column equilibration for isocratic analysis of acidic, basic, and neutral solutes in hydrophilic interaction liquid chromatography (HILIC) was compared using the mobile phase disturbance method, col... Read More about A study of column equilibration time in hydrophilic interaction chromatography.

Boxed interim evaluation report March 2018 (2018)
Report

BoxED is an outreach and widening participation initiative designed, developed and delivered by members of the Faculty of Health and Applied Sciences at the University of the West of England (UWE), Bristol. The scheme aims to provide inspirational an... Read More about Boxed interim evaluation report March 2018.

Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells (2018)
Journal Article

© 2018 The Author(s). Background: Mounting evidence suggests that one of the ways that cells adapt to hypoxia is through alternative splicing. The aim of this study was firstly to examine the effect of hypoxia on the alternative splicing of cancer as... Read More about Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells.

Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes (2018)
Journal Article

The potential for maternal nanoparticle (NP) exposures to cause developmental toxicity in the fetus without the direct passage of NPs has previously been shown, but the mechanism remained elusive. We now demonstrate that exposure of cobalt and chromi... Read More about Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes.

Molecular evidence of Cacao swollen shoot virus acquisition and retention by Planococcus citri (Risso) and Pseudococcus longispinus (Targioni-Tozzetti) and Pseudococcus viburni (Signoret) Mealybugs (Hemiptera: Pseudococcidae) (2018)
Journal Article

Cacao swollen shoot virus (CSSV) remains a significant viral pathogen endemic in West African cacao-growing countries. Eradication of affected trees (complete removal) and resistance breeding in existing cacao (Theobroma cacao L.) germplasm have not... Read More about Molecular evidence of Cacao swollen shoot virus acquisition and retention by Planococcus citri (Risso) and Pseudococcus longispinus (Targioni-Tozzetti) and Pseudococcus viburni (Signoret) Mealybugs (Hemiptera: Pseudococcidae).

Introducing the JMBE themed issue on science communication (2018)
Journal Article

No Abstract

Insect community composition and functional roles along a tropical agricultural production gradient (2018)
Journal Article

High intensity agricultural production systems are problematic not only for human health and the surrounding environment, but can threaten the provision of ecosystem services on which farm productivity depends. This research investigates the effects... Read More about Insect community composition and functional roles along a tropical agricultural production gradient.