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Tonsil T cell immunity to human papillomavirus in the absence of detectable virus in healthy adults (2008)
Journal Article
Hobbs, C. G., Groves, E., Davenport, V., Bailey, M., Williams, N. A., Birchall, M. A., & Heyderman, R. S. (2008). Tonsil T cell immunity to human papillomavirus in the absence of detectable virus in healthy adults. Laryngoscope, 118(3), 459-463. https://doi.org/10.1097/MLG.0b013e31815aedb3

BACKGROUND: Human papillomavirus (HPV) is known to infect the epithelium of the upper aerodigestive tract; however, major questions regarding prevalence and persistence of infection, and their relation to local immune response, remain unanswered. OBJ... Read More about Tonsil T cell immunity to human papillomavirus in the absence of detectable virus in healthy adults.

Can fluorescence spectrometry be used as a surrogate for the Biochemical Oxygen Demand (BOD) test in water quality assessment? An example from South West England (2008)
Journal Article
Hudson, N., Baker, A., Reynolds, D. M., Ward, D., Brunsdon, C., Carliell-Marquet, C., & Browning, S. (2008). Can fluorescence spectrometry be used as a surrogate for the Biochemical Oxygen Demand (BOD) test in water quality assessment? An example from South West England. Science of the Total Environment, 391(1), 149-158. https://doi.org/10.1016/j.scitotenv.2007.10.054

The fluorescence intensities of tryptophan-like, tyrosine-like and humic-like materials were determined using excitation-emission-matrices (EEMs) for a wide range of samples including natural surface waters, sewage and industrial effluents and waters... Read More about Can fluorescence spectrometry be used as a surrogate for the Biochemical Oxygen Demand (BOD) test in water quality assessment? An example from South West England.

The application of conducting polymer nanoparticle electrodes to the sensing of ascorbic acid (2008)
Journal Article
Ambrosi, A., Morrin, A., Smythe, M. R., & Killard, A. (2008). The application of conducting polymer nanoparticle electrodes to the sensing of ascorbic acid. Analytica Chimica Acta, 609(1), 37-43. https://doi.org/10.1016/j.aca.2007.12.017

An ascorbic acid sensor was fabricated via the drop-casting of dodecylbenzene sulphonic acid (DBSA)-doped polyaniline nanoparticles onto a screen-printed carbon-paste electrode. The modified electrode was characterised with respect to the numbers of... Read More about The application of conducting polymer nanoparticle electrodes to the sensing of ascorbic acid.

The biology and conservation of the fish assemblage of the Severn Estuary (cSAC) (2008)
Journal Article
Bird, D. J. (2008). The biology and conservation of the fish assemblage of the Severn Estuary (cSAC)

The Severn Estuary is the second largest estuary in the UK and has been designated a cSAC because it contains habitat types and species that are rare or threatened in Europe, including the anadromous river and sea lampreys and the twaite and allis sh... Read More about The biology and conservation of the fish assemblage of the Severn Estuary (cSAC).

To what extent are hepatic concentrations of heavy metals in Anguilla anguilla at a site in a contaminated estuary related to body size and age and reflected in the metallothionein concentrations? (2008)
Journal Article
Bird, D. J., Rotchell, J. M., Hesp, S. A., Newton, L. C., Hall, N. G., & Potter, I. C. (2008). To what extent are hepatic concentrations of heavy metals in Anguilla anguilla at a site in a contaminated estuary related to body size and age and reflected in the metallothionein concentrations?. Environmental Pollution, 151(3), 641-651. https://doi.org/10.1016/j.envpol.2007.03.018

We explored how hepatic [metal]s in Anguilla anguilla at a contaminated estuarine site are influenced by body size, age and season, and the extent that [Cu], [Cd] and [Zn]s are reflected in [metallothionein (MT)]s. Although each [metal] and [MT] incr... Read More about To what extent are hepatic concentrations of heavy metals in Anguilla anguilla at a site in a contaminated estuary related to body size and age and reflected in the metallothionein concentrations?.

Analysis of basic compounds by reversed-phase high-performance liquid chromatography using hybrid inorganic/organic phases at high pH (2008)
Journal Article
Davies, N. H., Euerby, M. R., & McCalley, D. V. (2008). Analysis of basic compounds by reversed-phase high-performance liquid chromatography using hybrid inorganic/organic phases at high pH. Journal of Chromatography A, 1178(1-2), 71-78. https://doi.org/10.1016/j.chroma.2007.11.040

The retention and mass overload of five bases and a quaternary ammonium compound were studied on a bridged ethyl hybrid inorganic/organic phase (XBridge C18) over a pH range 2.7-12.0 using acetonitrile-phosphate and carbonate buffers. Some comparison... Read More about Analysis of basic compounds by reversed-phase high-performance liquid chromatography using hybrid inorganic/organic phases at high pH.

To what extent are hepatic concentrations of heavy metals in Anguilla anguilla at a site in a contaminated estuary related to body size and age and reflected in the metallothionein concentrations? (2008)
Journal Article
Bird, D. J., Rotchell, J., Hesp, S., Newton, L. C., Hall, N., & Potter, I. (2008). To what extent are hepatic concentrations of heavy metals in Anguilla anguilla at a site in a contaminated estuary related to body size and age and reflected in the metallothionein concentrations?. Environmental Pollution, 151(3), 641-651. https://doi.org/10.1016/j.envpol.2007.03.018

Nitric oxide signalling in plants (2008)
Journal Article
Wilson, I. D., Neill, S., & Hancock, J. T. (2008). Nitric oxide signalling in plants. Plant, Cell and Environment, 31(5), 622-631. https://doi.org/10.1111/j.1365-3040.2007.01761.x

As with all organisms, plants must respond to a plethora of external environmental cues. Individual plant cells must also perceive and respond to a wide range of internal signals. It is now well-accepted that nitric oxide (NO) is a component of the r... Read More about Nitric oxide signalling in plants.

Identification of c-kit positive cells in rat urinary bladder and characterization of their functional role in spontaneous activity in control and diabetic bladders (2008)
Journal Article
Vahabi, B., Mckay, N. G., Lawson, K., & Sellers, D. J. (2008). Identification of c-kit positive cells in rat urinary bladder and characterization of their functional role in spontaneous activity in control and diabetic bladders. European Urology Supplements, 7(3), 181 - 181. https://doi.org/10.1016/S1569-9056%2807%2960992-0

Antioxidative responses in radish (Raphanus sativus L.) plants stressed by copper and lead in nutrient solution and soil (2008)
Journal Article
Teklic, T., Hancock, J. T., Engler, M., Paradikovic, N., Cesar, V., Lepeduš, H., …Bešlo, D. (2008). Antioxidative responses in radish (Raphanus sativus L.) plants stressed by copper and lead in nutrient solution and soil. Acta Biologica Cracoviensia Series Botanica, 50(2), 79-86

Radish (Raphanus sativus L.) is commonly grown in urban and suburban areas where the soil may be polluted with heavy metals such as Cu or Pb. In this study, short exposure of radish plantlets to 0.5 mM Cu or Pb in nutrient solution (two days) in grow... Read More about Antioxidative responses in radish (Raphanus sativus L.) plants stressed by copper and lead in nutrient solution and soil.

Meet the gene machine: stimulating bioethical discussions at school (2008)
Journal Article
Streith, L., Bultitude, K., Burnet, F., & Wilkinson, C. (2008). Meet the gene machine: stimulating bioethical discussions at school. Science in School, Autumn(Issue), 34-38

Laura Strieth, Karen Bultitude, Frank Burnet and Clare Wilkinson use drama and debate to encourage young people to discuss genetics and what it means for us all. Why not join in?

Nitric oxide, stomatal closure, and abiotic stress (2008)
Journal Article
Ribeiro, D., Harrison, J., Neill, S., Barros, R. S., Bright, J., Desikan, R., …Wilson, I. D. (2008). Nitric oxide, stomatal closure, and abiotic stress. Journal of Experimental Botany, 59(2), 165-176. https://doi.org/10.1093/jxb/erm293

Various data indicate that nitric oxide (NO) is an endogenous signal in plants that mediates responses to several stimuli. Experimental evidence in support of such signalling roles for NO has been obtained via the application of NO, usually in the fo... Read More about Nitric oxide, stomatal closure, and abiotic stress.

SlTPR1, a tomato tetratricopeptide repeat protein, interacts with the ethylene receptors NR and LeETR1, modulating ethylene and auxin responses and development (2008)
Journal Article
Lin, Z., Arciga-Reyes, L., Zhong, S., Alexander, L., Hackett, R., Wilson, I., & Grierson, D. (2008). SlTPR1, a tomato tetratricopeptide repeat protein, interacts with the ethylene receptors NR and LeETR1, modulating ethylene and auxin responses and development. Journal of Experimental Botany, 59(15), 4271-4287. https://doi.org/10.1093/jxb/ern276

The gaseous hormone ethylene is perceived by a family of ethylene receptors which interact with the Raf-like kinase CTR1. SlTPR1 encodes a novel TPR (tetratricopeptide repeat) protein from tomato that interacts with the ethylene receptors NR and LeET... Read More about SlTPR1, a tomato tetratricopeptide repeat protein, interacts with the ethylene receptors NR and LeETR1, modulating ethylene and auxin responses and development.

Tools to investigate ROS sensitive signalling proteins (2008)
Journal Article
Desikan, R., Neill, S., Slinn, J., & Hancock, J. T. (2008). Tools to investigate ROS sensitive signalling proteins. Methods in Molecular Biology, 476, 87-99. https://doi.org/10.1007/978-1-59745-129-1_7

The thiols groups of cysteine residues on proteins are attractive oxidative targets for modification by reactive oxygen species, such as hydrogen peroxide (H2O2). Such modification can lead to important cellular signaling processes that ultimately re... Read More about Tools to investigate ROS sensitive signalling proteins.

Hands-on science in schools: the enhancement and enrichment perspective (2008)
Journal Article
Bultitude, K. (2008). Hands-on science in schools: the enhancement and enrichment perspective. Science in Parliament -Harlow then London-, 65(3), 22-23

Within the UK there are a remarkable range of programmes and activities on offer which seek to enhance and enrich student experience of science in school. Offered by a wide range of organisations, including universities, learned societies, museums, c... Read More about Hands-on science in schools: the enhancement and enrichment perspective.

Universal computation with limited resources: Belousov-Zhabotinsky and physarum computers (2008)
Journal Article
Adamatzky, A., De Lacy Costello, B., & Shirakawa, T. (2008). Universal computation with limited resources: Belousov-Zhabotinsky and physarum computers. International Journal of Bifurcation and Chaos, 18(08), 2373-2389. https://doi.org/10.1142/S0218127408021750

Using the examples of an excitable chemical system (the Belousov-Zhabotinsky medium) and plasmodium of Physarum polycephalum we show that universal computation in a geometrically unconstrained medium is only possible when resources (excitability or c... Read More about Universal computation with limited resources: Belousov-Zhabotinsky and physarum computers.

Regulation of CYP2A6 protein expression by skatole, indole, and testicular steroids in primary cultured pig hepatocytes (2008)
Journal Article
Wood, J. D., Chen, G., Cue, R. A., Lundstrom, K., & Doran, O. (2008). Regulation of CYP2A6 protein expression by skatole, indole, and testicular steroids in primary cultured pig hepatocytes. Drug Metabolism and Disposition, 36(1), 56-60. https://doi.org/10.1124/dmd.107.017285

CYP2A6 is one of the enzymes involved in the hepatic metabolism of a naturally produced compound, skatole, in the pig. Low CYP2A6 activity has been linked to excessive accumulation of skatole in pig adipose tissue and development of the phenomenon "b... Read More about Regulation of CYP2A6 protein expression by skatole, indole, and testicular steroids in primary cultured pig hepatocytes.