All Outputs (66)

High throughput high content reverse genetics visual screens of ciliogenesis and cilia maintenance (2012)
Journal Article
Szymanska, K., Wheway, G., Natarajan, S., Higgins, J., Adams, M., Tomlinson, D. C., & Johnson, C. A. (2012). High throughput high content reverse genetics visual screens of ciliogenesis and cilia maintenance. Cilia, 1(S1), P49. https://doi.org/10.1186/2046-2530-1-S1-P49

Cilia are small, hair-like structures occurring on the apical surface of most of vertebrate cells. Defects in cilia cause a range of developmental phenotypes grouped into conditions called ciliopathies. Our aim is to dissect the structure and functio... Read More about High throughput high content reverse genetics visual screens of ciliogenesis and cilia maintenance.

Development of a novel, physiologically relevant cytotoxicity model: application to the study of chemotherapeutic damage to mesenchymal stromal cells (2012)
Journal Article
May, J. E., Morse, H. R., Xu, J., & Donaldson, C. (2012). Development of a novel, physiologically relevant cytotoxicity model: application to the study of chemotherapeutic damage to mesenchymal stromal cells. Toxicology and Applied Pharmacology, 263(3), 374-389. https://doi.org/10.1016/j.taap.2012.07.013

Prevalence and risk of violence against children with disabilities: A systematic review and meta-analysis of observational studies (2012)
Journal Article
Bellis, M. A., Jones, L., Wood, S., Hughes, K., McCoy, E., Eckley, L., …Officer, A. (2012). Prevalence and risk of violence against children with disabilities: A systematic review and meta-analysis of observational studies. Lancet, 380(9845), 899-907. https://doi.org/10.1016/S0140-6736%2812%2960692-8

Summary Background Globally, at least 93 million children have moderate or severe disability. Children with disabilities are thought to have a substantially greater risk of being victims of violence than are their non-disabled peers. Establishment of... Read More about Prevalence and risk of violence against children with disabilities: A systematic review and meta-analysis of observational studies.

Prevalence and risk of violence against adults with disabilities: A systematic review and meta-analysis of observational studies (2012)
Journal Article
Bellis, M. A., Hughes, K., Jones, L., Wood, S., Bates, G., Eckley, L., …Officer, A. (2012). Prevalence and risk of violence against adults with disabilities: A systematic review and meta-analysis of observational studies. Lancet, 379(9826), 1621-1629. https://doi.org/10.1016/S0140-6736%2811%2961851-5

Background About 15% of adults worldwide have a disability. These individuals are frequently reported to be at increased risk of violence, yet quantitative syntheses of studies of this issue are scarce. We aimed to quantify violence against adults wi... Read More about Prevalence and risk of violence against adults with disabilities: A systematic review and meta-analysis of observational studies.

Novel electrode reactions of diazepam, flunitrazepam and lorazepam and their exploitation in a new redox mode LC-DED assay for serum (2012)
Journal Article
Honeychurch, K. C., Chong, A. T., Elamin, K., & Hart, J. P. (2012). Novel electrode reactions of diazepam, flunitrazepam and lorazepam and their exploitation in a new redox mode LC-DED assay for serum. Analytical Methods, 4(1), 132-140. https://doi.org/10.1039/c1ay05419h

Previously unreported voltammetric redox behaviour was identified for flunitrazepam, lorazepam and diazepam at a glassy carbon electrode. This was successfully exploited for their determination in serum by high performance liquid chromatography dual... Read More about Novel electrode reactions of diazepam, flunitrazepam and lorazepam and their exploitation in a new redox mode LC-DED assay for serum.

Maintaining functional major histocompatibility complex diversity under inbreeding: The case of a selfing vertebrate (2012)
Journal Article
Allainguillaume, J., Ellison, A., Allainguillaume, J., Girdwood, S., Pachebat, J., Peat, K. M., …Consuegra, S. (2012). Maintaining functional major histocompatibility complex diversity under inbreeding: The case of a selfing vertebrate. Proceedings of the Royal Society B: Biological Sciences, 279(1749), 5004-5013. https://doi.org/10.1098/rspb.2012.1929

Major histocompatibility complex (MHC) genes encode proteins that present pathogen-derived antigens to T-cells, initiating the adaptive immune response in vertebrates. Although populations with low MHC diversity tend to be more susceptible to pathoge... Read More about Maintaining functional major histocompatibility complex diversity under inbreeding: The case of a selfing vertebrate.