Heterologous production of fungal maleidrides reveals the cryptic cyclization involved in their biosynthesis
(2016)
Journal Article
Williams, K., Szwalbe, A. J., Mulholland, N. P., Vincent, J. L., Bailey, A., Willis, C. L., …Cox, R. J. (2016). Heterologous production of fungal maleidrides reveals the cryptic cyclization involved in their biosynthesis. Angewandte Chemie International Edition, 55(23), 6784-6788. https://doi.org/10.1002/anie.201511882
Fungal maleidrides are an important family of bioactive secondary metabolites that consist of 7, 8, or 9-membered carbocycles with one or two fused maleic anhydride moieties. The biosynthesis of byssochlamic acid (a nonadride) and agnestadride A (a h... Read More about Heterologous production of fungal maleidrides reveals the cryptic cyclization involved in their biosynthesis.