Global hypomethylation of the genome in XX embryonic stem cells
(2005)
Journal Article
Zvetkova, I., Apedaile, A., Ramsahoye, B., Mermoud, J. E., Crompton, L., John, R., …Brockdorff, N. (2005). Global hypomethylation of the genome in XX embryonic stem cells. Nature Genetics, 37(11), 1274-1279. https://doi.org/10.1038/ng1663
Embryonic stem (ES) cells are important tools in the study of gene function and may also become important in cell therapy applications. Establishment of stable XX ES cell lines from mouse blastocysts is relatively problematic owing to frequent loss o... Read More about Global hypomethylation of the genome in XX embryonic stem cells.