Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome
(2013)
Journal Article
Wheway, G., Abdelhamed, Z., Natarajan, S., Toomes, C., Inglehearn, C., & Johnson, C. A. (2013). Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome. Developmental Biology, 377(1), 55-66. https://doi.org/10.1016/j.ydbio.2013.02.015
Meckel-Gruber syndrome (MKS) is an embryonic lethal ciliopathy resulting from mutations in genes encoding proteins localising to the primary cilium. Mutations in the basal body protein MKS1 account for 7% of cases of MKS. The condition affects the de... Read More about Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome.