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Outputs (31)

Estimation of bladder contractility from intravesical pressure–volume measurements (2016)
Journal Article
Fry, C. H., Gammie, A., Drake, M. J., Abrams, P., Kitney, D. G., & Vahabi, B. (2017). Estimation of bladder contractility from intravesical pressure–volume measurements. Neurourology and Urodynamics, 36(4), 1009-1014. https://doi.org/10.1002/nau.23047

© 2016 Wiley Periodicals, Inc. Aims: To describe parameters from urodynamic pressure recordings that describe urinary bladder contractility through the use of principles of muscle mechanics. Methods: Subtracted detrusor pressure and voided flow were... Read More about Estimation of bladder contractility from intravesical pressure–volume measurements.

The role of the mucosa in normal and abnormal bladder function (2016)
Journal Article
Fry, C. H., Fry, C., & Vahabi, B. (2016). The role of the mucosa in normal and abnormal bladder function. Basic and Clinical Pharmacology and Toxicology, 119(53), 57-62. https://doi.org/10.1111/bcpt.12626

© 2016 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society) The internal face of the detrusor smooth muscle wall of the urinary bladder is covered by a mucosa, separating muscle from the hostile environment of urine.... Read More about The role of the mucosa in normal and abnormal bladder function.

Physiological and pathophysiological implications of micromotion activity in urinary bladder function (2015)
Journal Article
Drake, M. J., Vahabi, B., Vahabi, B., & Drake, M. J. (2015). Physiological and pathophysiological implications of micromotion activity in urinary bladder function. Acta Physiologica, 213(2), 360-370. https://doi.org/10.1111/apha.12373

© 2014 Scandinavian Physiological Society. 'Micromotions' is a term signifying the presence of localized microcontractions and microelongations, alongside non-motile areas. The motile areas tend to shift over the bladder surface with time, and the in... Read More about Physiological and pathophysiological implications of micromotion activity in urinary bladder function.

Anoctamin-1 in the juvenile rat urinary bladder (2014)
Journal Article
Bijos, D. A., Drake, M. J., & Vahabi, B. (2014). Anoctamin-1 in the juvenile rat urinary bladder. PLoS ONE, 9(9), https://doi.org/10.1371/journal.pone.0106190

Purpose: To investigate presence, location and functional role of calcium-activated chloride channel (CaCC) Anoctamin-1 (Ano1) in rat urinary bladder. Materials and Methods: Bladders from 3 week old Wistar rats were studied. End-point PCR on total mR... Read More about Anoctamin-1 in the juvenile rat urinary bladder.

Trpm8 agonists modulate contraction of the pig urinary bladder (2013)
Journal Article
Parsons, B. A., Drake, M. J., Vahabi, B., Parsons, B. A., Doran, O., Rhodes, A., …Drake, M. (2013). Trpm8 agonists modulate contraction of the pig urinary bladder. Canadian Journal of Physiology and Pharmacology, 91(7), 503-509. https://doi.org/10.1139/cjpp-2012-0406

The transient receptor potential melastin-8 (TRPM8) channel is activated by the "cooling" compounds menthol and icilin. Pathophysiologically, it is implicated in the overactive bladder and bladder cooling reflex, but the activity of TRPM8 in normal b... Read More about Trpm8 agonists modulate contraction of the pig urinary bladder.

The validation of a functional, isolated pig bladder model for physiological experimentation (2012)
Journal Article
Fry, C. H., Drake, M. J., Parsons, B. A., Gammie, A., & Vahabi, B. (2012). The validation of a functional, isolated pig bladder model for physiological experimentation. Frontiers in Pharmacology, 3 APR(52), 1-8. https://doi.org/10.3389/fphar.2012.00052

Characterizing the integrative physiology of the bladder requires whole organ preparations. The purpose of this study was to validate an isolated large animal (pig) bladder preparation, through arterial and intravesical drug administration, intravesi... Read More about The validation of a functional, isolated pig bladder model for physiological experimentation.