Development of a three-dimensional in-vitro model of the human bone marrow using commercially available matrices and bone marrow derived mesenchymal stem cells/HS-5 stromal cell line (2016)
Thesis
Kabrah, S. Development of a three-dimensional in-vitro model of the human bone marrow using commercially available matrices and bone marrow derived mesenchymal stem cells/HS-5 stromal cell line. (Thesis). University of the West of England. Retrieved from https://uwe-repository.worktribe.com/output/10596716

The function of the bone marrow is known to be affected by both haematopoietic malignancies as well as the chemotherapy used to treat them. To appropriately evaluate the role of disease versus treatment, this study aimed to develop a novel three-dime... Read More about Development of a three-dimensional in-vitro model of the human bone marrow using commercially available matrices and bone marrow derived mesenchymal stem cells/HS-5 stromal cell line.

Development of an electrochemical assay for the illegal “fat burner” 2,4-dinitrophenol and its potential application in forensic and biomedical analysis (2016)
Journal Article
Honeychurch, K. C. (2016). Development of an electrochemical assay for the illegal “fat burner” 2,4-dinitrophenol and its potential application in forensic and biomedical analysis. Advances in Analytical Chemistry, 6(2), 41-48. https://doi.org/10.5923/j.aac.20160602.02

The illegal use of 2,4-dinitrophenol (24DNP) as a diet aid has increased markedly resulting in a number of deaths. This paper describes the development of a simple voltammetric method for the measurement of 24DNP in serum at glassy carbon electrode... Read More about Development of an electrochemical assay for the illegal “fat burner” 2,4-dinitrophenol and its potential application in forensic and biomedical analysis.

The global decline of cheetah Acinonyx jubatus and what it means for conservation (2016)
Journal Article
Durant, S. M., Mitchell, N., Groom, R., Pettorelli, N., Ipavec, A., Jacobson, A. P., …Young-Overton, K. (2017). The global decline of cheetah Acinonyx jubatus and what it means for conservation. Proceedings of the National Academy of Sciences, 114(3), 528-533. https://doi.org/10.1073/pnas.1611122114

Establishing and maintaining protected areas (PAs) are key tools for biodiversity conservation. However, this approach is insufficient for many species, particularly those that are wide-ranging and sparse. The cheetah Acinonyx jubatus exemplifies suc... Read More about The global decline of cheetah Acinonyx jubatus and what it means for conservation.

A loop-mediated isothermal amplification method for rapid direct detection and differentiation of nonpathogenic and verocytotoxigenic Escherichia coli in beef and bovine faeces (2016)
Journal Article
Stratakos, A. C., Stratakos, A., Linton, M., Millington, S., & Grant, I. R. (2017). A loop-mediated isothermal amplification method for rapid direct detection and differentiation of nonpathogenic and verocytotoxigenic Escherichia coli in beef and bovine faeces. Journal of Applied Microbiology, 122(3), 817-828. https://doi.org/10.1111/jam.13381

© 2016 The Society for Applied Microbiology Aim: To develop a multiplex loop-mediated isothermal amplification (LAMP) assay capable of quantifying Escherichia coli and differentiating verocytotoxigenic E.coli (VTEC). Methods and Results: Primer sets... Read More about A loop-mediated isothermal amplification method for rapid direct detection and differentiation of nonpathogenic and verocytotoxigenic Escherichia coli in beef and bovine faeces.

Cell Signalling (2016)
Book
Hancock, J. T. (2016). Cell Signalling. Oxford: Oxford University Press

4th Edition of Cell Signalling published by OUP

Effect of mobile phase additives on solute retention at low aqueous pH in hydrophilic interaction liquid chromatography (2016)
Journal Article
McCalley, D. V. (2017). Effect of mobile phase additives on solute retention at low aqueous pH in hydrophilic interaction liquid chromatography. Journal of Chromatography A, 1483, 71-79. https://doi.org/10.1016/j.chroma.2016.12.035

© 2016 Elsevier B.V. Trifluoracetic acid (TFA) added to the aqueous acetonitrile mobile phase induces some unexpected changes in the ionic component of retention in hydrophilic interaction separations when using Type B silica and amide-bonded silica... Read More about Effect of mobile phase additives on solute retention at low aqueous pH in hydrophilic interaction liquid chromatography.

EphA2 Drives the Segregation of Ras-Transformed Epithelial Cells from Normal Neighbors (2016)
Journal Article
Porazinski, S., de Navascués, J., Yako, Y., Hill, W., Jones, M. R., Maddison, R., …Hogan, C. (2016). EphA2 Drives the Segregation of Ras-Transformed Epithelial Cells from Normal Neighbors. Current Biology, 26(23), 3220-3229. https://doi.org/10.1016/j.cub.2016.09.037

© 2016 Elsevier Ltd In epithelial tissues, cells expressing oncogenic Ras (hereafter RasV12 cells) are detected by normal neighbors and as a result are often extruded from the tissue [1–6]. RasV12 cells are eliminated apically, suggesting that extrus... Read More about EphA2 Drives the Segregation of Ras-Transformed Epithelial Cells from Normal Neighbors.

A UK student survey investigating the effects of consuming alcohol mixed with energy drinks on overall alcohol consumption and alcohol-related negative consequences (2016)
Journal Article
Johnson, S. J., Alford, C., Stewart, K., & Verster, J. C. (2016). A UK student survey investigating the effects of consuming alcohol mixed with energy drinks on overall alcohol consumption and alcohol-related negative consequences. Preventive Medicine Reports, 4, 496-501. https://doi.org/10.1016/j.pmedr.2016.09.005

© 2016 The Authors Previous research reported positive associations between alcohol mixed with energy drink (AMED) consumption and overall alcohol consumption. However, results were largely based on between-subjects comparisons comparing AMED consume... Read More about A UK student survey investigating the effects of consuming alcohol mixed with energy drinks on overall alcohol consumption and alcohol-related negative consequences.

Recent advances in the fabrication and application of screen-printed electrochemical (bio)sensors based on carbon materials for biomedical, agri-food and environmental analyses (2016)
Journal Article
Pemberton, R. M., Crew, A., Hughes, G., Westmacott, K., Honeychurch, K. C., Crew, A. P., …Hart, J. P. (2016). Recent advances in the fabrication and application of screen-printed electrochemical (bio)sensors based on carbon materials for biomedical, agri-food and environmental analyses. Biosensors, 6(4), 50. https://doi.org/10.3390/bios6040050

This review describes recent advances in the fabrication of electrochemical (bio)sensors based on screen-printing technology involving carbon materials and their application in biomedical, agri-food and environmental analyses. It will focus on the va... Read More about Recent advances in the fabrication and application of screen-printed electrochemical (bio)sensors based on carbon materials for biomedical, agri-food and environmental analyses.

Review: The application of liquid chromatography electrochemical detection for the determination of drugs of abuse (2016)
Journal Article
Honeychurch, K., & Honeychurch, K. C. (2016). Review: The application of liquid chromatography electrochemical detection for the determination of drugs of abuse. Separations, 3(4), 28. https://doi.org/10.3390/separations3040028

© 2016 by the authors; licensee MDPI, Basel, Switzerland. This review (4 tables, 88 references) describes current developments in the design and application of liquid chromatography electrochemical detection (LC ED) based approaches for the determina... Read More about Review: The application of liquid chromatography electrochemical detection for the determination of drugs of abuse.

Web strategies for the curation and discovery of open educational resources (2016)
Journal Article
educational resources. Open Praxis, 8(4), 297-312. https://doi.org/10.5944/openpraxis.8.4.305

For those receiving funding from the UK HEFCE-funded Open Educational Resource Programme (2009 – 2012), the sustainability of project outputs was one of a number of essential goals. Our approach for the hosting and distribution of health and life sci... Read More about Web strategies for the curation and discovery of open educational resources.

Cercocebus sanjei (Mittermeier, 1986), Sanje River Mangabey (2016)
Book Chapter
Ehardt, C. L., Fernández, D., & McCabe, G. (2016). Cercocebus sanjei (Mittermeier, 1986), Sanje River Mangabey. In N. Rowe, & M. Myers (Eds.), All the World’s Primates. New York: Pogonias Press

N/A

Irritable bowel syndrome and active inflammatory bowel disease diagnosed by faecal gas analysis (2016)
Journal Article
Aggio, R. B., White, P., Jayasena, H., de Lacy Costello, B., Ratcliffe, N. M., & Probert, C. S. (2017). Irritable bowel syndrome and active inflammatory bowel disease diagnosed by faecal gas analysis. Alimentary Pharmacology and Therapeutics, 45(1), 82-90. https://doi.org/10.1111/apt.13822

© 2016 John Wiley & Sons Ltd Background: Inflammatory bowel disease and irritable bowel syndrome may present in a similar manner. Measuring faecal calprotectin concentration is often recommended to rule out inflammatory bowel disease, however, ther... Read More about Irritable bowel syndrome and active inflammatory bowel disease diagnosed by faecal gas analysis.

Ecological impact assessments fail to reduce risk of bat casualties at wind farms (2016)
Journal Article
Lintott, P., Richardson, S., Hosken, D., Fensome, S., & Mathews, F. (2016). Ecological impact assessments fail to reduce risk of bat casualties at wind farms. Current Biology, 26(21), R1135-R1136. https://doi.org/10.1016/j.cub.2016.10.003

Demand for renewable energy is rising exponentially. While this has benefits in reducing greenhouse gas emissions, there may be costs to biodiversity [1]. Environmental Impact Assessments (EIAs) are the main tool used across the world to predict the... Read More about Ecological impact assessments fail to reduce risk of bat casualties at wind farms.

A Printed and Microfabricated Sensor Device for the Sensitive Low Volume Measurement of Aqueous Ammonia (2016)
Journal Article
Killard, A. J., Brannelly, N. T., Brannelly, N., & Killard, A. (2017). A Printed and Microfabricated Sensor Device for the Sensitive Low Volume Measurement of Aqueous Ammonia. Electroanalysis, 29(1), 162-171. https://doi.org/10.1002/elan.201600556

© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim The measurement of low concentrations of ammonia in small sample volumes is required in biological, biomedical and environmental measurement applications. However, achieving this without instrumenta... Read More about A Printed and Microfabricated Sensor Device for the Sensitive Low Volume Measurement of Aqueous Ammonia.

Multi-locus sequence typing of Escherichia coli isolates with acquired ampC genes and ampC promoter mutations (2016)
Journal Article
Lawrance, L. M., Moore, P. C., Lewis, J. A., Moore, P. C. L., Arnold, D. L., & Lawrance, L. (2016). Multi-locus sequence typing of Escherichia coli isolates with acquired ampC genes and ampC promoter mutations. Diagnostic Microbiology and Infectious Disease, 86(3), 265-267. https://doi.org/10.1016/j.diagmicrobio.2016.08.008

© 2016 Elsevier Inc. Multi-locus sequence typing was used to reveal a high degree of diversity amongst the E. coli isolates with AmpC plasmid genes, and a high prevalence of the −32 mutation present.

Rapid detection of pathological mutations and deletions of the haemoglobin beta gene (HBB) by High Resolution Melting (HRM) analysis and Gene Ratio Analysis Copy Enumeration PCR (GRACE-PCR) (2016)
Journal Article
Turner, A., Sasse, J., & Varadi, A. (2016). Rapid detection of pathological mutations and deletions of the haemoglobin beta gene (HBB) by High Resolution Melting (HRM) analysis and Gene Ratio Analysis Copy Enumeration PCR (GRACE-PCR). BMC Medical Genetics, 17, Article 75. https://doi.org/10.1186/s12881-016-0334-y

© 2016 The Author(s). Objectives: Inherited disorders of haemoglobin are the world's most common genetic diseases, resulting in significant morbidity and mortality. The large number of mutations associated with the haemoglobin beta gene (HBB) makes g... Read More about Rapid detection of pathological mutations and deletions of the haemoglobin beta gene (HBB) by High Resolution Melting (HRM) analysis and Gene Ratio Analysis Copy Enumeration PCR (GRACE-PCR).

Experimentally comparing the attractiveness of domestic lights to insects: Do LEDs attract fewer insects than conventional light types? (2016)
Journal Article
Wakefield, A., Broyles, M., Stone, E. L., Jones, G., & Harris, S. (2016). Experimentally comparing the attractiveness of domestic lights to insects: Do LEDs attract fewer insects than conventional light types?. Ecology and Evolution, 6(22), 8028-8036. https://doi.org/10.1002/ece3.2527

© 2016 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. LED lighting is predicted to constitute 70% of the outdoor and residential lighting markets by 2020. While the use of LEDs promotes energy and cost savings relative to tr... Read More about Experimentally comparing the attractiveness of domestic lights to insects: Do LEDs attract fewer insects than conventional light types?.

Dual species biofilm culture of Staphylococcus aureus and a bioluminescent strain of Pseudomonas aeruginosa (2016)
Presentation / Conference
Steven, J., Robinson, G., & Nelson, S. (2016, October). Dual species biofilm culture of Staphylococcus aureus and a bioluminescent strain of Pseudomonas aeruginosa

Poster presentation. Introduction Pseudomonas aeruginosa and Staphylococcus aureus are significant pathogens of wounds and the cystic fibrosis lung. There are likely to be complex interactions between the two species, with biofilm co-culture aff... Read More about Dual species biofilm culture of Staphylococcus aureus and a bioluminescent strain of Pseudomonas aeruginosa.

Insulin receptor isoform variations in prostate cancer cells (2016)
Journal Article
Perks, C. M., Zielinska, H. A., Wang, J., Jarrett, C., Frankow, A., Ladomery, M. R., …Holly, J. M. P. (2016). Insulin receptor isoform variations in prostate cancer cells. Frontiers in Endocrinology, 7(SEP), https://doi.org/10.3389/fendo.2016.00132

� 2016 Perks, Zielinska, Wang, Jarrett, Frankow, Ladomery, Bahl, Rhodes, Oxley and Holly. Men who develop prostate cancer (PCa) increasingly have one of the co-morbidities associated with a Western lifestyle that are characterized by hyperinsulinem... Read More about Insulin receptor isoform variations in prostate cancer cells.