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John Hart's Outputs (52)

Redox mechanisms of rohypnol and mogadon and their exploitation in an assay using dual electrode ECD following HPLC (2012)
Presentation / Conference Contribution

Importance of the 1,4-benzodiazepine class of drugs

Cyclic voltammetric behaviour of Flunitrazepam (Rohypnol), and Nitrazepam (Mogadon)

Possible mechanism for their voltammetric behaviour
Optimisation of Liquid Chromatographic Separation and... Read More about Redox mechanisms of rohypnol and mogadon and their exploitation in an assay using dual electrode ECD following HPLC.

Studies towards the development of a screen-printed carbon electrochemical immunosensor array for mycotoxins: A sensor for aflatoxin B1
Presentation / Conference Contribution

Screen-printed carbon electrodes (SPCEs) bearing a surface-adsorbed antibody against aflatoxin B1 (AFB1) were used in a competitive immunoassay, based on competition of free analyte with a biotinylated aflatoxin B1 conjugate. Subsequent addition of s... Read More about Studies towards the development of a screen-printed carbon electrochemical immunosensor array for mycotoxins: A sensor for aflatoxin B1.

Selective and rapid biosensor integrated into a commercial hand-held instrument for the measurement of ammonium ion in sewage effluent
Presentation / Conference Contribution

A disposable biosensor for ammonium ions in sewage effluent was developed and based on a screen-printed carbon electrode coated with the enzyme glutamate dehydrogenase, 2-oxoglutarate, and NADH. This rapid and selective amperometric biosensor is capa... Read More about Selective and rapid biosensor integrated into a commercial hand-held instrument for the measurement of ammonium ion in sewage effluent.

A screen-printed, amperometric, biosensor array for the detection of organophosphate pesticides based on inhibition of wild type, and mutant acetylcholinesterases, from Drosophila melanogaster
Presentation / Conference Contribution

Screen-printed carbon electrodes (SPCEs) modified with cobalt phthalocyanine (CoPC) have been used as base transducers in the construction of amperometric pesticide biosensors. Six individual biosensors were fabricated by depositing wildtype (WT) ace... Read More about A screen-printed, amperometric, biosensor array for the detection of organophosphate pesticides based on inhibition of wild type, and mutant acetylcholinesterases, from Drosophila melanogaster.

Towards the development of molecularly imprinted polymer based screen-printed sensors for metabolites of PAHs
Presentation / Conference Contribution

This paper describes the fabrication of a sensor for 1-hydroxypyrene (1-OHP) based on a screen-printed carbon electrode (SPCE) modified with a molecularly imprinted polymer (MIP); 1-OHP was chosen as a model metabolite of polyaromatic hydrocarbons (P... Read More about Towards the development of molecularly imprinted polymer based screen-printed sensors for metabolites of PAHs.

Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes
Presentation / Conference Contribution

Background: The five antigens of the Yt blood group system are located on the membrane GPI‐linked erythrocyte acetylcholinesterase (AChE‐E), which is implicated in a range of clinical issues, including sleep apnoea and neurotoxin poisoning. Conformat... Read More about Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes.

Evaluation of a novel disposable amperometric glycerol biosensor based on a meldolas blue-modified screen-printed carbon electrode for juice beverage analysis
Presentation / Conference Contribution

This study details the design and development of an electrochemical biosensor for measuring glycerol, an important compound in food and beverages, due to its role as a naturally occurring triose sugar and food additive (E 422). Monitoring glycerol co... Read More about Evaluation of a novel disposable amperometric glycerol biosensor based on a meldolas blue-modified screen-printed carbon electrode for juice beverage analysis.