All Outputs (134)

The dual role of paramagnetic particles for integrated lysis and measurement in a rapid immunoassay for intracellular proteins (2013)
Journal Article

A novel, integrated lysis and immunoassay methodology and system for intracellular protein measurement are described. The method uses paramagnetic particles both as a lysis agent and assay label resulting in a rapid test requiring minimal operator in... Read More about The dual role of paramagnetic particles for integrated lysis and measurement in a rapid immunoassay for intracellular proteins.

Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome (2013)
Journal Article

Meckel-Gruber syndrome (MKS) is an embryonic lethal ciliopathy resulting from mutations in genes encoding proteins localising to the primary cilium. Mutations in the basal body protein MKS1 account for 7% of cases of MKS. The condition affects the de... Read More about Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome.

Monitoring the effects of fibrinogen concentration on blood coagulation using quartz crystal microbalance (QCM) and its comparison with thromboelastography (2013)
Presentation / Conference Contribution

A novel microfluidic anti-factor Xa assay device for monitoring anticoagulant therapy at the point-of-care. SPIE Microtechnologies (2013)
Presentation / Conference Contribution

Bristol inventor develops self-heating gloves (2013)
Digital Artefact

CoreGenes3.5: A webserver for the determination of core genes from sets of viral and small bacterial genomes (2013)
Journal Article

Background: CoreGenes3.5 is a webserver that determines sets of core genes from viral and small bacterial genomes as an automated batch process. Previous versions of CoreGenes have been used to classify bacteriophage genomes and mine data from pathog... Read More about CoreGenes3.5: A webserver for the determination of core genes from sets of viral and small bacterial genomes.

Microfabricated glucose biosensor for culture welloperation (2013)
Journal Article

A water-based carbon screen-printing ink formulation, containing the redox mediator cobalt phthalocyanine (CoPC) and the enzyme glucose oxidase (GOx), was investigated for its suitability to fabricate glucose microbiosensors in a 96-well microplate f... Read More about Microfabricated glucose biosensor for culture welloperation.

Beyond Markov chains, towards adaptive memristor network-based music generation (2013)
Presentation / Conference Contribution

We undertook a study of the use of a memristor network for music generation, making use of the memristor's memory to go beyond the Markov hypothesis. Seed transition matrices are created and populated using memristor equations, and which are shown to... Read More about Beyond Markov chains, towards adaptive memristor network-based music generation.

Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel - Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and wnt signalling defects (2013)
Journal Article

The ciliopathies are a group of heterogeneous diseases with considerable variations in phenotype for allelic conditions such as Meckel-Gruber syndrome (MKS) and Joubert syndrome (JBTS) even at the inter-individual level within families. In humans, mu... Read More about Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel - Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and wnt signalling defects.

Electrochemical detection of extracellular hydrogen peroxide in Arabidopsis thaliana: A real-time marker of oxidative stress (2013)
Journal Article

An electrochemical approach to directly measure the dynamic process of H2O2 release from cultures of Arabidopsis thaliana cells is reported. This approach is based on H2O2 oxidation on a Pt electrode in conjunction with continuous measurement of samp... Read More about Electrochemical detection of extracellular hydrogen peroxide in Arabidopsis thaliana: A real-time marker of oxidative stress.

Investigation on Cacao swollen shoot virus (CSSV) pollen transmission through cross-pollination (2013)
Journal Article

DNA- and RNA-based polymerase chain reaction (PCR) systems were used with Cacao swollen shoot virus (CSSV) primers designed from conserved regions of the six published genomic sequences of CSSV to investigate whether the virus is transmissible from i... Read More about Investigation on Cacao swollen shoot virus (CSSV) pollen transmission through cross-pollination.

Dendritic cell migration assay: A potential prediction model for identification of contact allergens (2013)
Journal Article

This manuscript describes methodology and a prediction model for the MUTZ-LC migration assay. The assay represents the physiological change in Langerhans cell (LC) behavior after exposure to a sensitizing chemical, resulting in LC migration from the... Read More about Dendritic cell migration assay: A potential prediction model for identification of contact allergens.

Recent developments in the stripping voltammetric determination of indium (2013)
Journal Article

The determination of indium has become increasingly more important as the demand for this metal has greatly increased in recent years for the manufacture of touch screen devices, photovoltaic and semi-conductor devices. Concentrations of In generally... Read More about Recent developments in the stripping voltammetric determination of indium.

Identification of volatile compounds as indicators of spoilage insects and mites in grain and flour (2013)
Thesis

Solid-phase micro-extraction (SPME) fibres and automated thermal desorption (ATD) tubes were used with gas chromatography-mass spectrometry (GC-MS), to investigate volatile secretions from the headspace gas of adults and larvae of confused flour bee... Read More about Identification of volatile compounds as indicators of spoilage insects and mites in grain and flour.

Boar taint: Challenges and opportunities (2013)
Presentation / Conference Contribution

An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome (2013)
Journal Article

Diagnosing irritable bowel syndrome (IBS) can be a challenge; many clinicians resort to invasive investigations in order to rule out other diseases and reassure their patients. Volatile organic metabolites (VOMs) are emitted from feces; understanding... Read More about An Investigation of Fecal Volatile Organic Metabolites in Irritable Bowel Syndrome.

Balancing selection and the maintenance of MHC supertype variation in a selfing vertebrate (2013)
Journal Article

Hepatic lipogenic enzyme expression in pigs is affected by selection for decreased backfat thickness at constant intramuscular fat content (2013)
Journal Article

This study investigated (i) whether genetic selection for decreased backfat thickness at constant intramuscular fat (IMF) affects the expression of lipogenic enzymes in pig liver and (ii) whether expression of the hepatic lipogenic enzymes is related... Read More about Hepatic lipogenic enzyme expression in pigs is affected by selection for decreased backfat thickness at constant intramuscular fat content.

Hepatic lipogenic enzymes expression in pigs is affected by selection for decreased backfat thickness at constant imtramuscular fat content (2013)
Journal Article

Volatiles from oral anaerobes confounding breath biomarker discovery (2013)
Journal Article

The levels of compounds in exhaled mouth air do not necessarily reflect levels in the systemic circulation as bacteria can bio-transform substrates to produce compounds within the mouth. This should be of concern to researchers measuring breath volat... Read More about Volatiles from oral anaerobes confounding breath biomarker discovery.