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A copper oxide/zinc oxide composite nano-surface for use in a biosensor

Cao, Lu; Kiely, Janice; Piano, Martina; Luxton, Richard

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Authors

Lu Cao

Janice Kiely Janice.Kiely@uwe.ac.uk
Professor in Bio-electronics/Res In CoDi

Martina Piano Martina.Piano@uwe.ac.uk
Research Fellow Biosensor reproducibility testing

Richard Luxton Richard.Luxton@uwe.ac.uk
Research Centre Director-IBST/Professor



Abstract

© 2019 by the authors. In this study, biosensors based on zinc oxide-copper oxide composite nano-surfaces were prepared using a simple and inexpensive distributed colloidal technique. Combinations of mixed dispersions with volume ratios of 1:1, 1:2 and 2:1 ZnO:CuO were compared. The uniform nano-crystalline sensor surfaces on polyethylene terephthalate (PET) were analysed using scanning electron microscopy (SEM), Atomic Force Microscopy (AFM) and Raman Spectroscopy. The ZnO-CuO composite biosensor nano-surfaces showed a significantly increased impedimetric signal compared with pure ZnO nanocrystals, and the maximum output was achieved with a volume ratio of 1:2 ZnO/CuO. The antibody capture of C-reactive protein (CRP) on the nano-surfaces was used to demonstrate the enhanced signal generated with increasing amounts of CuO in the nano-surface.

Citation

Cao, L., Kiely, J., Piano, M., & Luxton, R. (2019). A copper oxide/zinc oxide composite nano-surface for use in a biosensor. Materials, 12(7), 1126. https://doi.org/10.3390/ma12071126

Journal Article Type Article
Acceptance Date Apr 2, 2019
Publication Date Apr 6, 2019
Deposit Date May 31, 2019
Publicly Available Date May 31, 2019
Journal Materials
Print ISSN 1996-1944
Electronic ISSN 1996-1944
Publisher MDPI
Peer Reviewed Peer Reviewed
Volume 12
Issue 7
Pages 1126
DOI https://doi.org/10.3390/ma12071126
Keywords biosensor; impedance; ZnO–CuO; CRP
Public URL https://uwe-repository.worktribe.com/output/849023
Publisher URL https://doi.org/10.3390/ma12071126

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