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A copper oxide/zinc oxide composite nano-surface for use in a biosensor

Cao, Lu; Kiely, Janice; Piano, Martina; Luxton, Richard

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Authors

Lu Cao lu2.cao@live.uwe.ac.uk>

Janice Kiely Janice.Kiely@uwe.ac.uk
Professor in Bio-electronics/Res In CoDi

Martina Piano Martina.Piano@uwe.ac.uk
Research Fellow Biosensor reproducibility testing

Richard Luxton Richard.Luxton@uwe.ac.uk
Research Centre Director-IBST/Professor



Abstract

© 2019 by the authors. In this study, biosensors based on zinc oxide-copper oxide composite nano-surfaces were prepared using a simple and inexpensive distributed colloidal technique. Combinations of mixed dispersions with volume ratios of 1:1, 1:2 and 2:1 ZnO:CuO were compared. The uniform nano-crystalline sensor surfaces on polyethylene terephthalate (PET) were analysed using scanning electron microscopy (SEM), Atomic Force Microscopy (AFM) and Raman Spectroscopy. The ZnO-CuO composite biosensor nano-surfaces showed a significantly increased impedimetric signal compared with pure ZnO nanocrystals, and the maximum output was achieved with a volume ratio of 1:2 ZnO/CuO. The antibody capture of C-reactive protein (CRP) on the nano-surfaces was used to demonstrate the enhanced signal generated with increasing amounts of CuO in the nano-surface.

Journal Article Type Article
Publication Date Apr 6, 2019
Journal Materials
Print ISSN 1996-1944
Electronic ISSN 1996-1944
Publisher MDPI
Peer Reviewed Peer Reviewed
Volume 12
Issue 7
Pages 1126
APA6 Citation Cao, L., Kiely, J., Piano, M., & Luxton, R. (2019). A copper oxide/zinc oxide composite nano-surface for use in a biosensor. Materials, 12(7), 1126. https://doi.org/10.3390/ma12071126
DOI https://doi.org/10.3390/ma12071126
Keywords biosensor; impedance; ZnO–CuO; CRP
Publisher URL https://doi.org/10.3390/ma12071126

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