Outputs (1791)

Natural soundscapes enhance mood recovery amid anthropogenic noise pollution (2024)
Journal Article

In urbanised landscapes, the scarcity of green spaces and increased exposure to anthropogenic noise have adverse effects on health and wellbeing. While reduced speed limits have historically been implemented to address traffic safety, their potential... Read More about Natural soundscapes enhance mood recovery amid anthropogenic noise pollution.

Validation of a sensor system for the measurement of breath ammonia using selected-ion flow-tube mass spectrometry (2024)
Journal Article

The measurement of trace breath gases is of growing interest for its potential to provide non-invasive physiological information in health and disease. While instrumental techniques such as selected-ion flow-tube mass spectrometry (SIFT-MS) can achie... Read More about Validation of a sensor system for the measurement of breath ammonia using selected-ion flow-tube mass spectrometry.

Changes to virus taxonomy and the ICTV Statutes ratified by the International Committee on Taxonomy of Viruses (2024) (2024)
Journal Article

This article reports changes to virus taxonomy and taxon nomenclature that were approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in April 2024. The entire ICTV membership was invited to vote on 203 taxonomic proposal... Read More about Changes to virus taxonomy and the ICTV Statutes ratified by the International Committee on Taxonomy of Viruses (2024).

The role and function of the Forensic Science Regulator in the UK (2024)
Book Chapter

A Forensic Science Regulator's (FSR) role was established in England and Wales at a time when the UK forensic science sector was undergoing significant structural changes that would introduce commercialization—a system of direct charging for forensic... Read More about The role and function of the Forensic Science Regulator in the UK.

Forensic science and policing must listen and learn to regain declining public trust (2024)
Digital Artefact

Forensic science plays a key role in solving crimes as well as overturning wrongful convictions, but recent studies suggest public trust in forensic science is declining for a range of reasons. In this article, I talk about the need for a “collaborat... Read More about Forensic science and policing must listen and learn to regain declining public trust.

Recent knowledge on the applications of molecular hydrogen in plant physiology, crop production, and food processing (2024)
Journal Article

This is an Editorial for a Topics Issue. It briefly summarises the field, highlighting its importance. It also gives a brief overview of each of the papers published in that issue.

Reactive astrocytes generated from human iPSC are pro-inflammatory and display altered metabolism (2024)
Journal Article

Astrocytes are the most abundant type of glial cell in the central nervous system and they play pivotal roles in both normal health and disease. Their dysfunction is detrimental to many brain related pathologies. Under pathological conditions, such a... Read More about Reactive astrocytes generated from human iPSC are pro-inflammatory and display altered metabolism.

Identifying targetable metabolic dependencies across colorectal cancer progression (2024)
Journal Article

Colorectal cancer (CRC) is a multi-stage process initiated through the formation of a benign adenoma, progressing to an invasive carcinoma and finally metastatic spread. Tumour cells must adapt their metabolism to support the energetic and biosynthet... Read More about Identifying targetable metabolic dependencies across colorectal cancer progression.

Spliceosomal vulnerability of MYCN-amplified neuroblastoma is contingent on PRMT5-mediated regulation of epitranscriptomic and metabolomic pathways (2024)
Journal Article

Approximately 50% of poor prognosis neuroblastomas arise due to MYCN over-expression. We previously demonstrated that MYCN and PRMT5 proteins interact and PRMT5 knockdown led to apoptosis of MYCN amplified (MNA) neuroblastoma. Here we evaluate the hi... Read More about Spliceosomal vulnerability of MYCN-amplified neuroblastoma is contingent on PRMT5-mediated regulation of epitranscriptomic and metabolomic pathways.

Molecular hydrogen: A sustainable strategy for agricultural and food production challenges (2024)
Journal Article

The world is confronting numerous challenges, including global warming, health epidemics, and population growth, each presenting significant threats to the stability and sustainability of our planet's ecosystems. Such issues have collectively contrib... Read More about Molecular hydrogen: A sustainable strategy for agricultural and food production challenges.

Advances in cancer diagnosis and treatment (2024)
Journal Article

This Special Issue of the British Journal of Biomedical Science brings together a collection of articles which all contribute to the advancement of knowledge into the diagnosis and treatment of cancer. Each article in this diverse research field offe... Read More about Advances in cancer diagnosis and treatment.

Sensing solutions in soil biodiversity and carbon monitoring; from acoustics to biosensing (2024)
Presentation / Conference Contribution

This presentation formed an overview of the current research into the technologies we are developing in SOAS at UWE for the analysis of soil carbon dynamics and soil biodiversity. It highlights three main strands; electrochemical (bio)sensing, gas s... Read More about Sensing solutions in soil biodiversity and carbon monitoring; from acoustics to biosensing.

Interorgan, intraorgan and interplant communication mediated by nitric oxide and related species (2024)
Journal Article

Summary
Plant survival to a potential plethora of diverse environmental insults is underpinned by coordinated communication amongst organs to help shape effective responses to these environmental challenges at the whole plant level. This interorgan... Read More about Interorgan, intraorgan and interplant communication mediated by nitric oxide and related species.

Deletions in the MAL gene result in loss of Mal protein, defining the rare inherited AnWj-negative blood group phenotype (2024)
Journal Article

The genetic background of the high prevalence red blood cell antigen AnWj has remained unresolved since its identification in 1972, despite reported associations with both CD44 and Smyd1 histone methyltransferase. Development of anti-AnWj, which may... Read More about Deletions in the MAL gene result in loss of Mal protein, defining the rare inherited AnWj-negative blood group phenotype.

Development of biological recognition elements for the detection of the genome of cocoa swollen shoot virus (2024)
Thesis

Cacao swollen shoot virus (CSSV) is the main threat to chocolate production in West Africa. Infection causes a decrease in bean production yield and can cause tree death within three years, causing socio-economic damage to small-holding farmers.

C... Read More about Development of biological recognition elements for the detection of the genome of cocoa swollen shoot virus.

Differentiation of SH-SY5Y neuroblastoma cells using retinoic acid and BDNF: A model for neuronal and synaptic differentiation in neurodegeneration (2024)
Journal Article

There has been much interest in the use of cell culture models of neurones, to avoid the animal welfare and cost issues of using primary and human-induced pluripotent stem cell (hiPSC)-derived neurones respectively. The human neuroblastoma cell line,... Read More about Differentiation of SH-SY5Y neuroblastoma cells using retinoic acid and BDNF: A model for neuronal and synaptic differentiation in neurodegeneration.

Development of a disposable, amperometric glycerol biosensor based on a screen-printed carbon electrode, modified with the electrocatalyst meldolas blue, coated with glycerol dehydrogenase and NAD+: Application to the analysis of wine quality (2024)
Journal Article

This paper describes the design and development of a novel electrochemical biosensor for measuring glycerol in wine. Our initial detailed studies were aimed at deducing the optimum conditions for biosensor operation by conducting hydrodynamic voltamm... Read More about Development of a disposable, amperometric glycerol biosensor based on a screen-printed carbon electrode, modified with the electrocatalyst meldolas blue, coated with glycerol dehydrogenase and NAD+: Application to the analysis of wine quality.

Complete absence of GLUT1 does not impair human terminal erythroid differentiation (2024)
Journal Article

The Glucose transporter 1 (GLUT1) is one of the most abundant proteins within the erythrocyte membrane and is required for glucose and dehydroascorbic acid (Vitamin C precursor) transport. It is widely recognized as a key protein for red cell structu... Read More about Complete absence of GLUT1 does not impair human terminal erythroid differentiation.

The peer review process: Past, present, and future (2024)
Journal Article

The peer review process is a fundamental aspect of modern scientific paper publishing, underpinning essential quality control. First conceptualised in the 1700s, it is an iterative process that aims to elevate scientific literature to the highest sta... Read More about The peer review process: Past, present, and future.

IL-6 knockdown in a model of the human bone marrow, abrogates DNA damage induction in bystander cells post-chemotherapy induced cytokine release syndrome (2024)
Journal Article

Following infection or exposure to therapeutic agents, an aggressive immune response may result, termed cytokine storm (CS) or cytokine release syndrome. Here the innate immune system becomes uncontrolled, leading to serious consequences including po... Read More about IL-6 knockdown in a model of the human bone marrow, abrogates DNA damage induction in bystander cells post-chemotherapy induced cytokine release syndrome.