Outputs (124)

Use of artificial intelligence to manage patient flow in emergency department during the COVID-19 pandemic: A prospective, single-center study (2022)
Journal Article

BACKGROUND: During the coronavirus disease 2019 (COVID-19) pandemic, calculation of the number of emergency department (ED) beds required for patients with vs. without suspected COVID-19 represented a real public health problem. In France, Amiens Pic... Read More about Use of artificial intelligence to manage patient flow in emergency department during the COVID-19 pandemic: A prospective, single-center study.

Examining the epigenetic mechanisms of childhood adversity and sensitive periods: A gene set-based approach (2022)
Journal Article

Background: Sensitive periods are developmental stages of heightened plasticity when life experiences, including exposure to childhood adversity, have the potential to exert more lasting impacts. Epigenetic mechanisms, including DNA methylation (DNAm... Read More about Examining the epigenetic mechanisms of childhood adversity and sensitive periods: A gene set-based approach.

Medium term results of the cementless Oxford mobile bearing medial unicompartmental knee replacement (2022)
Journal Article

Abstract
Background
Medial Unicompartmental Knee Replacement (UKR) has well-documented benefits over Total Knee Replace-
ment in the treatment of anteromedial osteoarthritis of the knee. There has been an increasing move from cemented to
cementl... Read More about Medium term results of the cementless Oxford mobile bearing medial unicompartmental knee replacement.

Nasointestinal tube placement: Techniques that increase success (2022)
Journal Article

Background: Delayed gastric emptying (DGE) is a major cause of undernutrition that can be overcome using nasointestinal (NI) feeding, but tube placement often fails. We analyse which techniques enable successful NI tube placement. Methods: Efficacy o... Read More about Nasointestinal tube placement: Techniques that increase success.

Sensitive periods for the effect of childhood adversity on DNA methylation: Updated results from a prospective, longitudinal study (2022)
Journal Article

Short-Term safety outcomes of mastectomy and immediate prepectoral implant-based breast reconstruction: Pre-BRA prospective multicentre cohort study (2022)
Journal Article

Background: Prepectoral breast reconstruction (PPBR) has recently been introduced to reduce postoperative pain and improve cosmetic outcomes in women having implant-based procedures. High-quality evidence to support the practice of PPBR, however, is... Read More about Short-Term safety outcomes of mastectomy and immediate prepectoral implant-based breast reconstruction: Pre-BRA prospective multicentre cohort study.

Association between measures derived from children's primary exfoliated teeth and psychopathology symptoms: Results from a community-based study (2022)
Journal Article

Mental disorders are among the most disabling health conditions globally. However, there remains a lack of valid, reliable, noninvasive, and inexpensive biomarkers to identify (at an early age) people who are at the greatest risk of experiencing a fu... Read More about Association between measures derived from children's primary exfoliated teeth and psychopathology symptoms: Results from a community-based study.

Characterising recovery following abdominal aortic aneurysm repair using cardiopulmonary exercise testing and patient reported outcome measures (2022)
Journal Article

Purpose: Surgery is associated with a post-operative stress response, changes in cardiopulmonary reserve, and metabolic demand. Here recovery after abdominal aortic aneurysm repair is investigated using cardiopulmonary exercise testing and patient-re... Read More about Characterising recovery following abdominal aortic aneurysm repair using cardiopulmonary exercise testing and patient reported outcome measures.

Epidemiology and outcomes of tibial plateau fractures in adults aged 60 and over treated in the United Kingdom (2022)
Journal Article

Background: Tibial plateau fractures are common in older adults, often resulting from low-energy falls. Although lower limb fragility fracture care has evolved, the management of tibial plateau fractures in older patients remains poorly researched. T... Read More about Epidemiology and outcomes of tibial plateau fractures in adults aged 60 and over treated in the United Kingdom.

The CARe Burn Scale—Adult Form: Identifying the responsiveness and Minimal Important Difference (MID) values of a Patient Reported Outcome Measure (PROM) to assess quality of life for adults with a burn injury (2022)
Journal Article

The CARe Burn Scales are a suite of burn-specific PROMs for adults, children, young people, and parents affected by burns. This study aimed to determine the responsiveness and minimal important difference (MID) values of the Adult Form for use in adu... Read More about The CARe Burn Scale—Adult Form: Identifying the responsiveness and Minimal Important Difference (MID) values of a Patient Reported Outcome Measure (PROM) to assess quality of life for adults with a burn injury.

The spatio-temporal influence of atmospheric circulations on monthly precipitation in Great Britain (2022)
Journal Article

It has long been understood that the North Atlantic Oscillation (NAO) is a key driver of regional climate in Great Britain and across Europe. However, studies have also noted that there is spatio-temporal variability in NAO-rainfall signatures which... Read More about The spatio-temporal influence of atmospheric circulations on monthly precipitation in Great Britain.

Updates to data versions and analytic methods influence the reproducibility of results from epigenome-wide association studies (2022)
Journal Article

Introduction: Biomedical research has grown increasingly cooperative through the sharing of consortia-level epigenetic data. Since consortia preprocess data prior to distribution, new processing pipelines can lead to different versions of the same d... Read More about Updates to data versions and analytic methods influence the reproducibility of results from epigenome-wide association studies.

Frequency-dependent characteristics of nerve-mediated ATP and acetylcholine release from detrusor smooth muscle (2022)
Journal Article

New Findings: What is the central question of this study? Is the frequency dependence of co-transmitter release from postganglionic nerve fibres different for each transmitter? What is the main finding and its importance? Release of co-transmitters f... Read More about Frequency-dependent characteristics of nerve-mediated ATP and acetylcholine release from detrusor smooth muscle.

A novel, scalable social media-based intervention Warna-Warni Waktu to reduce body dissatisfaction among young Indonesian women: Protocol for a parallel randomized controlled trial (2022)
Journal Article

Background: Despite the prevalence of body dissatisfaction among young Indonesian women and its consequential negative impacts, there are currently no evidence-based, culturally appropriate interventions to tackle this issue. Therefore, there is a ne... Read More about A novel, scalable social media-based intervention Warna-Warni Waktu to reduce body dissatisfaction among young Indonesian women: Protocol for a parallel randomized controlled trial.

Insights into the dynamics of ligand-induced dimerisation via mathematical modelling and analysis (2022)
Journal Article

The vascular endothelial growth factor (VEGF) receptor (VEGFR) system plays a role in cancer and many other diseases. It is widely accepted that VEGFR receptors dimerise in response to VEGF binding. However, analysis of these mechanisms and their imp... Read More about Insights into the dynamics of ligand-induced dimerisation via mathematical modelling and analysis.

An acceptance and commitment therapy prototype mobile program for individuals with a visible difference: Mixed methods feasibility study (2022)
Journal Article

Background: Mobile apps may offer a valuable platform for delivering evidence-based psychological interventions for individuals with atypical appearances, or visible differences, who experience psychosocial appearance concerns such as appearance-base... Read More about An acceptance and commitment therapy prototype mobile program for individuals with a visible difference: Mixed methods feasibility study.

‘Dove Confident Me Indonesia: Single Session’: Study protocol for a randomised controlled trial to evaluate a school-based body image intervention among Indonesian adolescents (2021)
Journal Article

Background: Due to the prevalence and associated adverse health consequences of negative body image among adolescents globally, there is a need to develop acceptable, effective, and scalable interventions. School-based body image interventions delive... Read More about ‘Dove Confident Me Indonesia: Single Session’: Study protocol for a randomised controlled trial to evaluate a school-based body image intervention among Indonesian adolescents.

Testing the responsiveness of and defining MID (minimal important difference) values for the CARe Burn Scales: Patient-reported outcome measures (PROMs) to assess quality of life for children and young people affected by burn injuries, and their parents/caregivers (2021)
Journal Article

Background: The CARe Burn Scales are a portfolio of burn-specific PROMs for people affected by burns, including a Child Form (for children < 8 years (Parent-proxy)), a Young Person Form (for young people aged 8 -17 years), an Adult Form, and a Parent... Read More about Testing the responsiveness of and defining MID (minimal important difference) values for the CARe Burn Scales: Patient-reported outcome measures (PROMs) to assess quality of life for children and young people affected by burn injuries, and their parents/caregivers.

Neurocognitive function following out-of-hospital cardiac arrest: A systematic review (2021)
Journal Article

Objectives: The primary aim of this review was to investigate neurocognitive outcomes following out-of-hospital cardiac arrest (OHCA). Specifically, the focus was on identifying the different neurocognitive domains that are assessed, the measures use... Read More about Neurocognitive function following out-of-hospital cardiac arrest: A systematic review.

Ordinal Logistic Regression as an alternative analysis strategy for the comparison of two independent samples (2021)
Journal Article

The two group between subjects design is pervasive with analyses often performed using the Mann Whitney Rank Sum test or using the Welch variant of the t-test. Using simulation it is shown that a dummy variable ordinal logistic regression (OLR) mode... Read More about Ordinal Logistic Regression as an alternative analysis strategy for the comparison of two independent samples.