Olena Doran's Outputs (93)

Breed-specific differences in the expression of the hepatic and testicular 3beta-hydroxysteroid dehydrogenase (HSD3B) and sulfotransferase 2B1 (SULT2B1)in boars with high and low backfat androstenone levels (2007)
Journal Article

Breed-associated variations in the sequence of the pig 3β- hydroxysteroid dehydrogenase gene (2007)
Journal Article

The entire sequence of the pig 3β-hydroxysteroid dehydrogenase (3β-HSD) gene has recently become known. This gene is deemed to be important in androstenone metabolism in pig liver, and its defective expression has been shown to be related to androste... Read More about Breed-associated variations in the sequence of the pig 3β- hydroxysteroid dehydrogenase gene.

The effect of low protein diets on fat deposition in pigs (2007)
Journal Article

Relationship between the expression of hepatic but not testicular 3β-hydroxysteroid dehydrogenase with androstenone deposition in pig adipose tissue (2006)
Journal Article

This study investigated the relationship between expression of hepatic and testicular 3/3-hydroxysteroid dehydrogenase (3/3-HSD) and accumulation of androstenone in adipose tissue because of its relation to boar taint. The experiments were performed... Read More about Relationship between the expression of hepatic but not testicular 3β-hydroxysteroid dehydrogenase with androstenone deposition in pig adipose tissue.

A reduced protein diet induces stearoyl-CoA desaturase protein expression in pig muscle but not in subcutaneous adipose tissue: Relationship with intramuscular lipid formation (2006)
Journal Article

A reduced protein diet (RPD) is known to increase the level of intramuscular lipid in pig meat with a smaller effect on the amount of subcutaneous adipose tissue. This might be due to tissue-specific activation of the expression of lipogenic enzymes... Read More about A reduced protein diet induces stearoyl-CoA desaturase protein expression in pig muscle but not in subcutaneous adipose tissue: Relationship with intramuscular lipid formation.

Functional analyses of the pig CYP2E1 promoter and identification of the transcription factors required for CYP2E1 expression (2006)
Book Chapter

Cloning and mapping of the porcine cytochrome-p450 2E1 gene and its association with skatole levels in the domestic pig (2005)
Journal Article

The porcine cytochrome-p450 2E1 (CYP2E1) gene was isolated by screening a pig BAC library and partially sequenced. This sequence information was used to identify six single nucleotide polymorphisms (SNPs) within the CYP2E1 gene and its promoter. In a... Read More about Cloning and mapping of the porcine cytochrome-p450 2E1 gene and its association with skatole levels in the domestic pig.

Sus scrofa partial CYP2E1 gene for cytochrome p450 2E1, exon 9 and partial CDS (2005)
Other

Sus scrofa partial CYP2E1 gene for cytochrome p450 2E1, exon 6 and partial CDS (2005)
Other

Sus scrofa mRNA for cytochrome p450 2E1 (CYP2E1 gene) (2005)
Other

Characterisation of 3-beta-hydroxysteroid dehydrogenase from pig liver and testis in relation to boar taint (2005)
Journal Article

Inhibition of CYP2E1 expression by androstenone: Relation to boar taint (2005)
Book Chapter

Sus scrofa partial CYP2E1 gene for cytochrome p450 2E1, partial promoter, exon 1 and partial CDS (2005)
Other

The molecular mechanisms of inhibitory effect of androstenone on hepatic skatole metabolism in relation to boar taint (2005)
Journal Article

The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone (2004)
Journal Article

Functional analysis of the pig cytochrome P4502E1 (CYP2E1) promoter identified two major activating elements. One corresponded to the hepatic nuclear factor 1 (HNF-1) consensus binding sequence at nucleotides -128/-98 and the other was located in the... Read More about The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone.

Characterisation of androstenone metabolism in pig liver microsomes (2004)
Journal Article

Androstenone (5α-androst-16-en-3-one) is a steroid pheromone produced in the testis. Excessive accumulation of androstenone together with skatole (3-methyl-indole) in the adipose tissue of some male pigs leads to "boar taint". In isolated pig hepatoc... Read More about Characterisation of androstenone metabolism in pig liver microsomes.

Effect of diet and age on delta-9-desaturase expression in pigs in relation to intramusclular lipid formation (2004)
Book Chapter

Relationship between skatole and androstenone accumulation in Meishan pigs - the role of cytochrome P450IIE! expression (2004)
Journal Article

The effect of age on the level of lipogenic enzymes in subcutaneouse fat and muscle of pigs (2004)
Journal Article

Liver androstenone metabolism in relation to boar taint (2003)
Book Chapter