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Outputs (28)

Understanding factors influencing the implementation of medicine risk communications by healthcare professionals in clinical practice: A systematic review using the Theoretical Domains Framework (2023)
Journal Article
Alharbi, A. B., Berrou, I., Umaru, N., Al Hamid, A., & Shebl, N. A. (2024). Understanding factors influencing the implementation of medicine risk communications by healthcare professionals in clinical practice: A systematic review using the Theoretical Domains Framework. Research in Social and Administrative Pharmacy, 20(2), 86-98. https://doi.org/10.1016/j.sapharm.2023.10.004

Background: Adverse drug reactions (ADRs) are known to cause hospitalisation, longer hospital stays, as well as higher healthcare costs and mortality. Unrecognised ADRs are anticipated throughout the medicine lifecycle as, before the medicine reaches... Read More about Understanding factors influencing the implementation of medicine risk communications by healthcare professionals in clinical practice: A systematic review using the Theoretical Domains Framework.

SegCrop: Segmentation-based dynamic cropping of endoscopic videos to address label leakage in surgical tool detection (2023)
Presentation / Conference
Qayyum, A., Bilal, M., Qadir, J., Caputo, M., Vohra, H., Akinosho, T., …Abioye, S. (2023, April). SegCrop: Segmentation-based dynamic cropping of endoscopic videos to address label leakage in surgical tool detection. Paper presented at IEEE International Symposium on Biomedical Imaging (ISBI), 2023, Colombia

In recent times, surgical data science has emerged as an important research discipline in interventional healthcare. There are many potential applications for analysing endoscopic surgical videos using machine learning (ML) techniques such as surgica... Read More about SegCrop: Segmentation-based dynamic cropping of endoscopic videos to address label leakage in surgical tool detection.

463 Understanding the role of nurses in deprescribing medicines for older people: A systematic review (2023)
Journal Article
Hart, L., & Berrou, I. (2023). 463 Understanding the role of nurses in deprescribing medicines for older people: A systematic review. International Journal of Pharmacy Practice, 31(Supplement 1), i18-i19. https://doi.org/10.1093/ijpp/riad021.020

Introduction: It is predicted that by 2035, two-thirds of people aged over 65 in the UK will be living with multiple health conditions requiring a life-long intake of multiple medicines (1). Recent reports suggest that over 8.4 million people take 5... Read More about 463 Understanding the role of nurses in deprescribing medicines for older people: A systematic review.

Making the case for pharmacogenomics in the management of mental health conditions (2023)
Journal Article
Berrou, I., Ramsunder, A., & Palmer, R. (2023). Making the case for pharmacogenomics in the management of mental health conditions. Pharmaceutical Journal, 310, 7969. https://doi.org/10.1211/PJ.2023.1.171747

Mental health conditions are the largest single cause of disability in the UK and among the top ten causes of disability worldwide. The prevalence of mental health conditions is increasing rapidly, especially since the COVID-19 pandemic. Overall, the... Read More about Making the case for pharmacogenomics in the management of mental health conditions.

Are you talking about me? Patients’ involvement in curriculum design and development (2022)
Presentation / Conference
Piggin, C., Moreno-Chamorro, D., Bowles, A., & Berrou, I. (2022, October). Are you talking about me? Patients’ involvement in curriculum design and development. Poster presented at 8th International Nurse Education Conference 19-22 October 2022 Sitges, Barcelona, Spain

Background: Patients have always been involved in the delivery and assessment of learning in our independent prescribing programme. However, they have not been extensively involved in curriculum design. Aim: We sought to develop a framework of pat... Read More about Are you talking about me? Patients’ involvement in curriculum design and development.

Diabetes self-management app: Systematic review of adoption determinants and future research agenda (2022)
Journal Article
Alaslawi, H., Berrou, I., Al Hamid, A., Alhuwail, D., & Aslanpour, Z. (2022). Diabetes self-management app: Systematic review of adoption determinants and future research agenda. JMIR Diabetes, 7(3), e28153. https://doi.org/10.2196/28153

Background: Most diabetes management involves self-management. Effective self-management of the condition improves diabetes control, reduces the risk of complications, and improves patient outcomes. Mobile apps for diabetes self-management (DSM) can... Read More about Diabetes self-management app: Systematic review of adoption determinants and future research agenda.

Factors influencing the implementation of medicine risk communications by healthcare professionals in clinical practice: A systematic review (2022)
Journal Article
Alharbi, A. B., Berrou, I., Umaru, N., Al Hamid, A., & Shebl, N. A. (2023). Factors influencing the implementation of medicine risk communications by healthcare professionals in clinical practice: A systematic review. Research in Social and Administrative Pharmacy, 19(1), 28-56. https://doi.org/10.1016/j.sapharm.2022.07.003

Background: Regulatory medicines risk communications aim to prevent patient harm through the dissemination of safety information to healthcare professionals (HCPs), patients, and the public. Evidence suggests that in addition to implementing the requ... Read More about Factors influencing the implementation of medicine risk communications by healthcare professionals in clinical practice: A systematic review.

Leaving no one behind: Interventions and outcomes of the COVID-19 vaccine maximising uptake programme (2022)
Journal Article
Berrou, I., Hamilton, K., Cook, C., Armour, C., Hughes, S., Hancock, J., …Walsh, N. (2022). Leaving no one behind: Interventions and outcomes of the COVID-19 vaccine maximising uptake programme. Vaccines, 10(6), 840. https://doi.org/10.3390/vaccines10060840

The devastating impact of COVID-19 on individuals and communities has accelerated the development of vaccines and the deployment of ambitious vaccination programmes to reduce the risks of infection, infection transmission and symptom severity. Howeve... Read More about Leaving no one behind: Interventions and outcomes of the COVID-19 vaccine maximising uptake programme.

Clinical efficacy of hydroxychloroquine in patients with COVID-19: Findings from an observational comparative study in Saudi Arabia (2021)
Journal Article
Alghamdi, S., Barakat, B., Berrou, I., Alzahrani, A., Haseeb, A., Hammad, M. A., …Albanghali, M. (2021). Clinical efficacy of hydroxychloroquine in patients with COVID-19: Findings from an observational comparative study in Saudi Arabia. Antibiotics, 10(4), 365. https://doi.org/10.3390/antibiotics10040365

The aim of this study was to assess the clinical effectiveness of Hydroxychloroquine-based regimens versus standard treatment in patients with the coronavirus disease admitted in 2019 to a hospital in Saudi Arabia. A comparative observational study,... Read More about Clinical efficacy of hydroxychloroquine in patients with COVID-19: Findings from an observational comparative study in Saudi Arabia.

Antimicrobial stewardship program implementation in a Saudi medical city: An exploratory case study (2021)
Journal Article
Alghamdi, S., Berrou, I., Bajnaid, E., Aslanpour, Z., Haseeb, A., Hammad, M. A., & Shebl, N. (2021). Antimicrobial stewardship program implementation in a Saudi medical city: An exploratory case study. Antibiotics, 10(3), Article 280. https://doi.org/10.3390/antibiotics10030280

Antimicrobial stewardship programs (ASPs) in hospitals have long been shown to improve antimicrobials’ use and reduce the rates of antimicrobial resistance. However, their implementation in hospitals, especially in developing countries such as Saudi... Read More about Antimicrobial stewardship program implementation in a Saudi medical city: An exploratory case study.

Antimicrobial stewardship programmes in Saudi hospitals: Evidence from a national survey (2021)
Journal Article
Alghamdi, S., Berrou, I., Aslanpour, Z., Mutlaq, A., Haseeb, A., Albanghali, M., …Shebl, N. (2021). Antimicrobial stewardship programmes in Saudi hospitals: Evidence from a national survey. Antibiotics, 10(2), Article 193. https://doi.org/10.3390/antibiotics10020193

© 2021 by the authors. Licensee MDPI, Basel, Switzerland. Saudi hospitals and healthcare facilities are facing increasing rates of antimicrobial resistance and the emergence of new multi-drug resistant strains. This is placing an unprecedented threat... Read More about Antimicrobial stewardship programmes in Saudi hospitals: Evidence from a national survey.

Antibiotics' use in Thailand: Community pharmacists' knowledge, attitudes and practices (2021)
Journal Article
Siltrakool, B., Berrou, I., Griffiths, D., & Alghamdi, S. (2021). Antibiotics' use in Thailand: Community pharmacists' knowledge, attitudes and practices. Antibiotics, 10(2), Article 137. https://doi.org/10.3390/antibiotics10020137

Thailand spends $203 million on antibiotics every year, and patients can still access antimicrobials over the counter without a prescription. Community pharmacy plays a pivotal role in improving access and ensuring the appropriate use of antimicrobia... Read More about Antibiotics' use in Thailand: Community pharmacists' knowledge, attitudes and practices.

Perceptions regarding antimicrobial use and resistance among adult hospital patients in Saudi Arabian Ministry of Health (MOH) Hospitals (2020)
Journal Article
Alghamdi, S., Berrou, I., Aslanpour, Z., Bajnaid, E., Alzahrani, A., & Shebl, N. A. (2020). Perceptions regarding antimicrobial use and resistance among adult hospital patients in Saudi Arabian Ministry of Health (MOH) Hospitals. Saudi Pharmaceutical Journal, 28(12), 1648-1654. https://doi.org/10.1016/j.jsps.2020.10.011

Background: Education, a key strategy within antimicrobial stewardship programmes (ASPs), has been mainly directed towards healthcare professionals and prescribers more than hospitalised patients. Aim: To examine patients' knowledge and perceptions o... Read More about Perceptions regarding antimicrobial use and resistance among adult hospital patients in Saudi Arabian Ministry of Health (MOH) Hospitals.

Status and trends of e-Health tools in Kuwait: A narrative review (2019)
Journal Article
Alaslawi, H., Berrou, I., Alhuwail, D., & Aslanpour, Z. (2019). Status and trends of e-Health tools in Kuwait: A narrative review. Journal of Health Informatics in Developing Countries, 13(2),

Background: Kuwait is witnessing an alarming increase in diabetes and high prevalence of multi-drug resistant strains. E-Health solutions have the potential to deliver timely, quality and cost-effective solutions to these public health challenges. Ho... Read More about Status and trends of e-Health tools in Kuwait: A narrative review.

Exploring the determinants of mobile health adoption by hospitals in China: Empirical study (2019)
Journal Article
Ramdani, B., Duan, B., & Berrou, I. (2020). Exploring the determinants of mobile health adoption by hospitals in China: Empirical study. JMIR Medical Informatics, 8(7), Article e14795. https://doi.org/10.2196/14795

Background: Although mobile health (mHealth) has the potential to transform health care by delivering better outcomes at a much lower cost than traditional health care services, little is known about mHealth adoption by hospitals. Objective: Thi... Read More about Exploring the determinants of mobile health adoption by hospitals in China: Empirical study.

Barriers to implementing antimicrobial stewardship programmes in three Saudi hospitals: Evidence from a qualitative study (2019)
Journal Article
Alghamdi, S., Atef-Shebl, N., Aslanpour, Z., & Berrou, I. (2019). Barriers to implementing antimicrobial stewardship programmes in three Saudi hospitals: Evidence from a qualitative study. Journal of Global Antimicrobial Resistance, 18, 284-290. https://doi.org/10.1016/j.jgar.2019.01.031

© 2019 International Society for Chemotherapy of Infection and Cancer Objectives: This study explored antimicrobial stewardship programme (ASP) team members’ perspectives regarding factors influencing the adoption and implementation of these programm... Read More about Barriers to implementing antimicrobial stewardship programmes in three Saudi hospitals: Evidence from a qualitative study.

This girl can: Analysis of women’s Facebook posts (2018)
Presentation / Conference
Berrou, I., & Cumberbatch, Y. (2018, September). This girl can: Analysis of women’s Facebook posts. Poster presented at 78th FIP World Congress of Pharmacy and Pharmaceutical Sciences, Glasgow, Scotland

Conference poster

Hospital adoption of antimicrobial stewardship programmes in Gulf Cooperation Council countries: A review of existing evidence (2018)
Journal Article
Alghamdi, S., Shebl, N. A., Aslanpour, Z., Shibl, A., & Berrou, I. (2018). Hospital adoption of antimicrobial stewardship programmes in Gulf Cooperation Council countries: A review of existing evidence. Journal of Global Antimicrobial Resistance, 15, 196-209. https://doi.org/10.1016/j.jgar.2018.07.014

© 2018 International Society for Chemotherapy of Infection and Cancer Antimicrobial resistance is increasing at an alarming rate in the Gulf Cooperation Council (GCC) owing to the overuse and misuse of antimicrobials. Novel and rare multidrug-resista... Read More about Hospital adoption of antimicrobial stewardship programmes in Gulf Cooperation Council countries: A review of existing evidence.

Patient safety culture in Saudi hospitals: Pharmacists and technicians perspectives (2017)
Presentation / Conference
Berrou, I., Alshehri, I., & Alruqayb, W. (2017, December). Patient safety culture in Saudi hospitals: Pharmacists and technicians perspectives. Poster presented at The Royal Pharmaceutical Society Winter Summit: Bridging the gap between industry, academia, policy and practice, London, England

Conference poster

The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression (2010)
Journal Article
Lynch, J. T., Rajendran, R., Xenaki, G., Berrou, I., Demonacos, C., & Krstic-Demonacos, M. (2010). The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression. Molecular Cancer, 9(38), 1-15. https://doi.org/10.1186/1476-4598-9-38

Background: The cyclin-dependent kinase (CDK) and mitogen-activated protein kinase (MAPK) mediated phosphorylation of glucocorticoid receptor (GR) exerts opposite effects on GR transcriptional activity and affects other posttranslational modification... Read More about The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression.

ROS & energy production pathways in the determination of resistance/sensitivity to glucocorticoids-induced apoptosis in acute lymphoblastic leukaemia
Thesis
Berrou, I. ROS & energy production pathways in the determination of resistance/sensitivity to glucocorticoids-induced apoptosis in acute lymphoblastic leukaemia. (Thesis). The University of Manchester. Retrieved from https://uwe-repository.worktribe.com/output/950671

Glucocorticoids have long been used in the treatment of acute lymphoblastic leukaemia due to their ability to cause cell cycle arrest and apoptosis of lymphoid cells. However, some patients do not respond to glucocorticoid treatment and the majority,... Read More about ROS & energy production pathways in the determination of resistance/sensitivity to glucocorticoids-induced apoptosis in acute lymphoblastic leukaemia.

Molecular mechanisms conferring resistance/sensitivity to glucocorticoid-induced apoptosis
Book Chapter
Berrou, I., Krstic-Demonacos, M., & Demonacos, C. Molecular mechanisms conferring resistance/sensitivity to glucocorticoid-induced apoptosis. In X. Xiaoxi Qian (Ed.), Glucocorticoids - New Recognition of Our Familiar Friend. IntechOpen. https://doi.org/10.5772/51467

Resistance to glucocorticoid induced apoptosis in acute lymphoblastic leukaemia (ALL) has been attributed to several different processes and pathways including predominance of certain GR isoforms with reduced transcriptional activity, either due to a... Read More about Molecular mechanisms conferring resistance/sensitivity to glucocorticoid-induced apoptosis.