Prof. Tony Killard's Outputs (24)

Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti-FXa assays (2011)
Journal Article

Novel and sensitive plate-based fluorogenic anti-factor Xa (FXa) assays were investigated to quantify unfractionated heparin (UFH) in human plasma and whole blood within the therapeutic ranges of 0-1.6. U/mL and 0-0.8. U/mL, respectively. Two fluorog... Read More about Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti-FXa assays.

Comparison of a fluorogenic anti-FXa assay with a central laboratory chromogenic anti-FXa assay for measuring LMWH activity in patient plasmas (2011)
Journal Article

Introduction: Low molecular weight heparins (LMWHs) are used worldwide for the treatment and prophylaxis of thromboembolic disorders. Routine laboratory tests are not required due to the predictable pharmacokinetics of LMWHs, with the exception of pr... Read More about Comparison of a fluorogenic anti-FXa assay with a central laboratory chromogenic anti-FXa assay for measuring LMWH activity in patient plasmas.

Comparison of the anticoagulant response of a novel fluorogenic anti-FXa assay with two commercial anti-FXa chromogenic assays (2011)
Journal Article

Introduction: Fast and accurate monitoring is crucial in the successful regulation of coagulation therapy. For the treatment of venous thromboembolism, both unfractionated heparin (UFH) and low molecular weight heparins (LMWHs) are commonly administe... Read More about Comparison of the anticoagulant response of a novel fluorogenic anti-FXa assay with two commercial anti-FXa chromogenic assays.

New developments in printable biosensors (2011)
Presentation / Conference Contribution

Printed polyaniline-modified interdigitated electrodes for detection and quantification of ammonia in breath (2011)
Presentation / Conference Contribution

A range of pathological conditions can lead to elevated blood ammonia and urea nitrogen levels. These include kidney and liver dysfunction and urea cycle defects. These conditions result in severe reduction in quality and quantity of life. Blood nitr... Read More about Printed polyaniline-modified interdigitated electrodes for detection and quantification of ammonia in breath.

Electrochemical sensing devices: From printed materials to printed integration (2011)
Presentation / Conference Contribution

In an analogy with silicon-based electronics, novel sensing and biosensing technologies must keep pace with the demands of increased sophistication, greater functionality, improved performance, and greater intelligence while still being low cost and... Read More about Electrochemical sensing devices: From printed materials to printed integration.

Inkjet-printed polyaniline nanoparticle electrodes for detection and quantification of ammonia in breath (2011)
Presentation / Conference Contribution

Wholly printed polypyrrole-based biosensor on flexible substrate (2011)
Presentation / Conference Contribution

Printed sensor devices: From materials fabrication to commercial applications (2011)
Presentation / Conference Contribution

Fabrication of inkjet printed interdigitated electrodes and arrays for gas detection (2011)
Presentation / Conference Contribution

A printed electrocatalyst for H2O2 reduction (2011)
Presentation / Conference Contribution

Opportunities for sensors in printed electronics (2011)
Presentation / Conference Contribution

Opportunities for sensors in printed electronics (2011)
Presentation / Conference Contribution

Electrochemical sensor strips were one of the first devices to become a global success in what might now be termed the printed electronics industry. Since their creation some 20 years ago, printed sensor strips are used extensively for a range of cli... Read More about Opportunities for sensors in printed electronics.

Enhanced electrochemical reduction of hydrogen peroxide at surfactant/salt modified electrodes (2011)
Presentation / Conference Contribution

Hydrogen peroxide (H2O2) is widely used in many biological systems and industrial processes in the textile, food, pharmaceutical and clinical sectors. The importance of hydrogen peroxide is related to its unique oxidising properties as well as decomp... Read More about Enhanced electrochemical reduction of hydrogen peroxide at surfactant/salt modified electrodes.

Breath ammonia levels in a normal human population study as determined by photoacoustic laser spectroscopy (2011)
Journal Article

Photoacoustic laser spectroscopy was used as a technique to measure real-time levels of ammonia in exhaled human breath in a small, locally recruited, normal healthy population (n = 30). This yielded an average level of breath ammonia of 265 ppb, ran... Read More about Breath ammonia levels in a normal human population study as determined by photoacoustic laser spectroscopy.

Chronocoulometric determination of urea in human serum using an inkjet printed biosensor (2011)
Journal Article

A biosensor for the determination of urea in human serum was fabricated using a combination of inkjet printed polyaniline nanoparticles and inkjet printed urease enzyme deposited sequentially onto screen-printed carbon paste electrodes. Chronocoulome... Read More about Chronocoulometric determination of urea in human serum using an inkjet printed biosensor.

Evaluation of activated partial thromboplastin time (aPTT) reagents for application in biomedical diagnostic device development (2011)
Journal Article

Introduction: The most commonly used test for monitoring heparin therapy is the activated partial thromboplastin time (aPTT). The response of available aPTT reagents to heparin varies significantly. The aim of this study was to highlight the differen... Read More about Evaluation of activated partial thromboplastin time (aPTT) reagents for application in biomedical diagnostic device development.

Electrochemical sensors: From probes to integrated smart systems (2011)
Presentation / Conference Contribution

The emergence of the field of electroanalytical chemistry has transformed measurement science. Early application of electrochemical probes for simple ionic species has given way to more sophisticated measurements involving further chemo-selective and... Read More about Electrochemical sensors: From probes to integrated smart systems.

Development of a fluorescent method for detecting the onset of coagulation in human plasma on microstructured lateral flow platforms (2011)
Journal Article

Microfluidic devices and microsystems have been used to develop blood coagulation monitoring devices for point of care diagnostic use. However, many of them suffer from inherent variability and imprecision, partly due to the fact that they only detec... Read More about Development of a fluorescent method for detecting the onset of coagulation in human plasma on microstructured lateral flow platforms.

Inkjet printable polyaniline-gold dispersions (2011)
Journal Article

Inkjet printable polyaniline-gold (PANI-Au) hybrid dispersions were synthesised using gold salt as oxidant to simultaneously induce chemical oxidative polymerisation of aniline and reduction of HAuCl4 in bulk aqueous solution. By varying the amount o... Read More about Inkjet printable polyaniline-gold dispersions.