All Outputs (135)

Forensic science in Ghana: A review (2019)
Journal Article

The use of forensic science continues to grow across the world. In Ghana, major advancements took off in 2011, including the introduction of modern DNA profiling and the establishment of an automated fingerprint identification system. These developme... Read More about Forensic science in Ghana: A review.

The Great Escape: Exploring ‘Escape Rooms’ as science communication interventions (2019)
Presentation / Conference Contribution

Escape rooms are a recent cultural phenomena, whereby a group of players are locked in a room and must solve a series of clues, puzzles, or mysteries in order to escape. From an educational perspective, escape rooms have been praised for offering a m... Read More about The Great Escape: Exploring ‘Escape Rooms’ as science communication interventions.

The rise of science comedy: Comparing shows at science and arts festivals (2019)
Presentation / Conference Contribution

Live science comedy shows have exploded in the past decade in the UK. These shows can range from stand-up comedy to musical theatre to panel shows and variety shows. However, there is very little empirical work exploring the rise in live science come... Read More about The rise of science comedy: Comparing shows at science and arts festivals.

Nitric Oxide-Induced Tolerance in Plants under Adverse Environmental Conditions (2019)
Book Chapter

An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics (2019)
Journal Article

Background
The majority of in vitro studies of medically relevant biofilms involve the development of biofilm on an inanimate solid surface. However, infection in vivo consists of biofilm growth on, or suspended within, the semi-solid matrix of the... Read More about An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics.

Aluminium Induced DNA-damage and Oxidative Stress in Cultures of the Marine Sponge Hymeniacidon perlevis (2019)
Journal Article

Aluminium is the most abundant element in the earth crust, and has no known biological function. However, it is an established neurotoxicant in its trivalent oxidation state, with exposure resulting in neurodegenerative diseases like Parkinson’s dise... Read More about Aluminium Induced DNA-damage and Oxidative Stress in Cultures of the Marine Sponge Hymeniacidon perlevis.

Leukaemic and bone marrow stromal cells alter cytarabine genotoxicity and cytotoxicity in favour of disease (2019)
Presentation / Conference Contribution

Resistance to therapy remains one of the greatest challenges in the management of the blood and bone marrow (BM) disorder, acute myeloid leukaemia (AML). This study aimed to investigate how leukaemic and BM stromal cells contribute to altered chemo-s... Read More about Leukaemic and bone marrow stromal cells alter cytarabine genotoxicity and cytotoxicity in favour of disease.

An in vitro investigation of microbial volatile analysis for diagnosis of wound infection (2019)
Thesis

Microorganisms produce a wide range of volatile compounds as a product of metabolism. As a result of their different metabolic capabilities, the profiles of volatiles produced will differ between species. This research investigates the detection of v... Read More about An in vitro investigation of microbial volatile analysis for diagnosis of wound infection.

The Campylobacter jejuni type VI secretion system enhances the oxidative stress response and host colonization (2019)
Journal Article

The role of the Type VI secretion system (T6SS) in Campylobacter jejuni is poorly understood despite an increasing prevalence of the T6SS in recent C. jejuni isolates in humans and chickens. The T6SS is a contractile secretion machinery capable of de... Read More about The Campylobacter jejuni type VI secretion system enhances the oxidative stress response and host colonization.

Initial trail results of a magnetic biosensor for the rapid detection of Porcine Reproductive and Respiratory Virus (PRRSV) infection (2019)
Journal Article

© 2019 The resonant coil magnetometer quantifies paramagnetic particles (PMPs) and has been used to develop magneto-immunoassays in a range of formats. The advantage of magneto-immunoassays is that they are relatively inexpensive, portable, easy to p... Read More about Initial trail results of a magnetic biosensor for the rapid detection of Porcine Reproductive and Respiratory Virus (PRRSV) infection.

Narrative, drama and science communication (2019)
Book Chapter

This chapter considers the role that narrative, as a means of storytelling, could have in science communication, a practice which is often seen as translating information from the specialist language of science into words and concepts that can be und... Read More about Narrative, drama and science communication.

Density functional theory transition-state modeling for the prediction of Ames mutagenicity in 1,4 Michael acceptors (2019)
Journal Article

Assessing the safety of new chemicals, without introducing the need for animal testing, is a task of great importance. The Ames test, a widely used bioassay to assess mutagenicity, can be an expensive, wasteful process with animal-derived reagents. E... Read More about Density functional theory transition-state modeling for the prediction of Ames mutagenicity in 1,4 Michael acceptors.

Effects of a modified tai chi program on older people with mild dementia: A randomized controlled trial (2019)
Journal Article

© 2019-IOS Press and the authors. All rights reserved. Background: Tai Chi exercise is a non-pharmacological therapy that has received increased attention in recent years. A Tai Chi program has been specifically modified for older people with cogniti... Read More about Effects of a modified tai chi program on older people with mild dementia: A randomized controlled trial.

Science Hunters: Teaching science concepts in schools using Minecraft (2019)
Journal Article

Background
Science Hunters is an outreach project based at Lancaster University, UK. It uses the computer game Minecraft, alongside interactive discussion and hands-on demonstrations, to engage children with scientific research topics and science l... Read More about Science Hunters: Teaching science concepts in schools using Minecraft.

Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML). (2019)
Presentation / Conference Contribution

Mesenchymal stromal cells (MSC) are known to protect leukemic cells from drug-induced toxicity within the bone marrow (BM) niche, however, less is known about leukemic impact on supportive MSC. The nucleoside-analogue, cytarabine (Ara-C), is a front-... Read More about Influence of Bone Marrow Stromal and Leukemic Cells on Cytarabine Chemo-Toxicity in Acute Myeloid Leukemia (AML)..

Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method (2019)
Journal Article

© 2019 Elsevier B.V. This is the first report on the fabrication, characterisation and application of an electrochemical (bio)sensor system for the simultaneous measurement of skatole and androstenone. A biosensor for androstenone was fabricated usin... Read More about Novel, rapid, low-cost screen-printed (bio)sensors for the direct analysis of boar taint compounds androstenone and skatole in porcine adipose tissue: Comparison with a high-resolution gas chromatographic method.

The development of point-of-use treatment technologies for the production of drinking water (2019)
Thesis

An estimated 884 million people worldwide lack access to drinking water from improved water sources. With the global population expected to reach eleven billion by the end of the 21st Century, stress on water and energy resources will be exacerbated.... Read More about The development of point-of-use treatment technologies for the production of drinking water.

Review of electroanalytical-based approaches for the determination of benzodiazepines (2019)
Journal Article

The benzodiazepine class of drugs are characterised by a readily electrochemically reducible azomethine group. A number are also substituted by other electrochemically active nitro, N-oxide, and carbonyl groups, making them readily accessible to elec... Read More about Review of electroanalytical-based approaches for the determination of benzodiazepines.

The imitation game (2019)
Journal Article

Actor Benedict Cumberbatch talks to Andrew Glester about what it's like to play famous scientists

Bird's nest ferns promote resource sharing by centipedes (2019)
Journal Article

Bird's nest ferns (Asplenium spp.) support large numbers of invertebrates, including centipedes. As top invertebrate predators, centipedes drive ecosystem function, for example, by regulating decomposer populations, but we know little of their ecolog... Read More about Bird's nest ferns promote resource sharing by centipedes.