All Outputs (87)

Comparative analysis of 37 Acinetobacter bacteriophages (2017)
Journal Article

© 2017 by the authors. Licensee MDPI, Basel, Switzerland. Members of the genus Acinetobacter are ubiquitous in the environment and the multipledrug resistant species A. baumannii is of significant clinical concern. This clinical relevance is currentl... Read More about Comparative analysis of 37 Acinetobacter bacteriophages.

Setting up a cohort study in speech and language therapy: Lessons from The UK Cleft Collective Speech and Language (CC-SL) Study (2017)
Journal Article

Background: Efforts to increase the evidence base in speech and language therapy are often limited by methodological factors which have restricted the strength of the evidence to the lower levels on the evidence hierarchy. Where higher graded studies... Read More about Setting up a cohort study in speech and language therapy: Lessons from The UK Cleft Collective Speech and Language (CC-SL) Study.

A study of the analysis of acidic solutes by hydrophilic interaction chromatography (2017)
Journal Article

© 2017 Elsevier B.V. The analysis of acidic solutes was compared on a cross-linked bonded amino phase and a neutral hybrid inorganic-organic amide phase, previously shown to give reasonable retention of acidic solutes. The amino column gave strong se... Read More about A study of the analysis of acidic solutes by hydrophilic interaction chromatography.

Ecobat: An online resource to facilitate transparent, evidence-based interpretation of bat activity data (2017)
Journal Article

© 2017 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. Acoustic surveys of bats are one of the techniques most commonly used by ecological practitioners. The results are used in Ecological Impact Assessments to assess the lik... Read More about Ecobat: An online resource to facilitate transparent, evidence-based interpretation of bat activity data.

Assessment of a combined gas chromatography mass spectrometer sensor system for detecting biologically relevant volatile compounds (2017)
Journal Article

© 2017 IOP Publishing Ltd. There have been a number of studies in which metal oxide sensors (MOS) have replaced conventional analytical detectors in gas chromatography systems. However, despite the use of these instruments in a range of applications... Read More about Assessment of a combined gas chromatography mass spectrometer sensor system for detecting biologically relevant volatile compounds.

The STARTEC decision support tool for better tradeoffs between food safety, quality, nutrition, and costs in production of advanced ready-to-eat foods (2017)
Journal Article

A prototype decision support IT-tool for the food industry was developed in the STARTEC project. Typical processes and decision steps were mapped using real life production scenarios of participating food companies manufacturing complex ready-to-eat... Read More about The STARTEC decision support tool for better tradeoffs between food safety, quality, nutrition, and costs in production of advanced ready-to-eat foods.

Physical conditions regulate the fungal to bacterial ratios of a tropical suspended soil (2017)
Journal Article

As a source of ‘suspended soils’, epiphytes contribute large amounts of organic matter to the canopy of tropical rain forests. Microbes associated with epiphytes are responsible for much of the nutrient cycling taking place in rain forest canopies. H... Read More about Physical conditions regulate the fungal to bacterial ratios of a tropical suspended soil.

Hypoxia modulates the stem cell population and induces EMT in the MCF-10A breast epithelial cell line (2017)
Journal Article

A common feature among pre-malignant lesions is the induction of hypoxia through increased cell propagation and reduced access to blood flow. Hypoxia in breast cancer has been associated with poor patient prognosis, resistance to chemotherapy and inc... Read More about Hypoxia modulates the stem cell population and induces EMT in the MCF-10A breast epithelial cell line.

Chernobyl; The disaster zone becomes a laboratory (2017)
Journal Article

Zapping plants with radiation might not initially appear useful, however Prof Neil Willey from the University of the West of England monitors the responses of plants under conditions similar to those at the infamous Chernobyl site, and for good reaso... Read More about Chernobyl; The disaster zone becomes a laboratory.

A novel mechanism linking memory stem cells with innate immunity in protection against HIV-1 infection (2017)
Journal Article

© 2017 The Author(s). HIV infection affects 37 million people and about 1.7 million are infected annually. Among the phase III clinical trials only the RV144 vaccine trial elicited significant protection against HIV-1 acquisition, but the efficacy an... Read More about A novel mechanism linking memory stem cells with innate immunity in protection against HIV-1 infection.

Hydrological legacy determines the type of enzyme inhibition in a peatlands chronosequence (2017)
Journal Article

© 2017 The Author(s). Peatland ecosystems contain one-third of the world's soil carbon store and many have been exposed to drought leading to a loss of carbon. Understanding biogeochemical mechanisms affecting decomposition in peatlands is essential... Read More about Hydrological legacy determines the type of enzyme inhibition in a peatlands chronosequence.

Temporal effects of disturbance on community composition in simulated stage-structured plant communities (2017)
Journal Article

© 2017 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. In an era of global environmental change, understanding how disturbance affects the dynamics of ecological communities is crucial. However, few studies have theoretically... Read More about Temporal effects of disturbance on community composition in simulated stage-structured plant communities.

Next generation sequencing elucidates cacao badnavirus diversity and reveals the existence of more than ten viral species (2017)
Journal Article

© 2017 Elsevier B.V. Cacao swollen shoot virus is a member of the family Caulimoviridae, genus Badnavirus and is naturally transmitted to Theobroma cacao (L.) by several mealybug species. CSSV populations in West African countries are highly variable... Read More about Next generation sequencing elucidates cacao badnavirus diversity and reveals the existence of more than ten viral species.

LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity (2017)
Journal Article

© The Author(s) named above 2018. Background:LGR5 serves as a co-receptor for Wnt/β-catenin signalling and marks normal intestinal stem cells; however, its role in colorectal cancer (CRC) remains controversial. LGR5 + cells are known to exist outside... Read More about LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity.

Distribution of the branched-chain α-ketoacid dehydrogenase complex E1α subunit and glutamate dehydrogenase in the human brain and their role in neuro-metabolism (2017)
Journal Article

© 2017 Glutamate is the major excitatory neurotransmitter of the central nervous system, with the branched-chain amino acids (BCAAs) acting as key nitrogen donors for de novo glutamate synthesis. Despite the importance of these major metabolites, the... Read More about Distribution of the branched-chain α-ketoacid dehydrogenase complex E1α subunit and glutamate dehydrogenase in the human brain and their role in neuro-metabolism.

Hydrogen gas and its role in cell signaling (2017)
Journal Article

Hydrogen gas (H2) was once thought to be inert in biological systems but it has now become apparent that exposure of a wide range of organisms, including animals and plants, to H2 or hydrogen-rich water (HRW) has beneficial effects. It is involved in... Read More about Hydrogen gas and its role in cell signaling.

The impact of ageing reveals distinct roles for human dentate gyrus and CA3 in pattern separation and object recognition memory (2017)
Journal Article

© 2017 The Author(s). Both recognition of familiar objects and pattern separation, a process that orthogonalises overlapping events, are critical for effective memory. Evidence is emerging that human pattern separation requires dentate gyrus. Dentate... Read More about The impact of ageing reveals distinct roles for human dentate gyrus and CA3 in pattern separation and object recognition memory.

Science at the Fringe (2017)
Journal Article

Andrew Glester visits this year's Edinburgh Festival Fringe and seeks out science-themed shows

Effects of High Pressure on Phospholipid Bilayers (2017)
Journal Article

© 2017 American Chemical Society. The response of lipid membranes to changes in external pressure is important for many biological processes, and it can also be exploited for technological applications. In this work, we employ all-atom molecular dyna... Read More about Effects of High Pressure on Phospholipid Bilayers.

The effect of listening to Holy Quran recitation on weaning patients receiving mechanical ventilation in the intensive care unit: A pilot study (2017)
Journal Article

Mechanical ventilation (MV) causes high level of stress in hospitalized patients. Weaning is the gradual process of decreasing ventilator support that in turn lead to termination of MV and increased respiratory effort, which may exacerbate symptoms a... Read More about The effect of listening to Holy Quran recitation on weaning patients receiving mechanical ventilation in the intensive care unit: A pilot study.