All Outputs (35)

An inexpensive, fast and sensitive quantitative lateral flow magneto-immunoassay for total prostate specific antigen (2014)
Journal Article

We describe the detection characteristics of a device the Resonant Coil Magnetometer (RCM) to quantify paramagnetic particles (PMPs) in immunochromatographic (lateral flow) assays. Lateral flow assays were developed using PMPs for the measurement of... Read More about An inexpensive, fast and sensitive quantitative lateral flow magneto-immunoassay for total prostate specific antigen.

The dual role of paramagnetic particles for integrated lysis and measurement in a rapid immunoassay for intracellular proteins (2013)
Journal Article

A novel, integrated lysis and immunoassay methodology and system for intracellular protein measurement are described. The method uses paramagnetic particles both as a lysis agent and assay label resulting in a rapid test requiring minimal operator in... Read More about The dual role of paramagnetic particles for integrated lysis and measurement in a rapid immunoassay for intracellular proteins.

Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles (2013)
Journal Article

Magnetic immunoassays have been shown to have similar detection limits to conventional immunoassays, with the advantage of reduced total assay time. The aim of this study was to demonstrate that an integrated lysis and measurement system could be use... Read More about Novel immunoassay technique for rapid measurement of intracellular proteins using paramagnetic particles.

Robust feature extraction from impedimetric signals using wavelet packet decomposition with application to cytotoxicity testing (2012)
Journal Article

Impedance-based cytotoxicity testing provides a simple, real-time and non-invasive assay technique that interferes minimally with cell morphology and function. In this study, impedimetric measurements of ECV304 cells with increasing concentrations of... Read More about Robust feature extraction from impedimetric signals using wavelet packet decomposition with application to cytotoxicity testing.

Non-linear data analysis of impedance spectroscopy as applied to cellular toxicity systems (2012)
Presentation / Conference Contribution

This paper introduces an impedance measurement system that can be performed non-destructively to detect cellular toxicity with a cell culture system. This study examines ECV304 cells grown in culture well and exposed to toxicant dimethyl sulphoxide... Read More about Non-linear data analysis of impedance spectroscopy as applied to cellular toxicity systems.

Comparison of cytotoxic changes in ECV304 cell through exposure to DMSO and sodium butyrate using impedance spectroscopy (2012)
Journal Article

This paper decides an impedance spectroscopy measurement system for real-time monitoring of cellular toxicity. The system is used to compare the impedance response of ECV304 cells to two toxicants, dimethyl sulphoxide (DMSO) and sodium butyrate. The... Read More about Comparison of cytotoxic changes in ECV304 cell through exposure to DMSO and sodium butyrate using impedance spectroscopy.

Hilbert huang transform impedance measurement data for cellular toxicity monitoring (2009)
Presentation / Conference Contribution

This paper investigates the Hilbert-Huang transformation (HHT), which is adaptive analysis of nonlinear and non-stationary signals. The aim of this study is to apply HHT to impedance measurement data analysis in order to discriminate different types... Read More about Hilbert huang transform impedance measurement data for cellular toxicity monitoring.

Evaluation of paramagnetic particles for use in a resonant coil magnetometer based magneto-immunoassay (2009)
Journal Article

This paper describes work that formed a part of an investigation to increase the detection sensitivity of a magneto-immunoassay. The study involved the characterisation of paramagnetic particles (PMPs) from a range of manufacturers in order to determ... Read More about Evaluation of paramagnetic particles for use in a resonant coil magnetometer based magneto-immunoassay.

Spot test: new technologies bring point-of-care testing into the 21st century (2009)
Journal Article

Every new technology offers the potential to effect changes in practise; many developments driven by the world-wide demand for instant results. This is never as true as in the arena of diagnostic testing. Once the sole preserve of the hospital labo... Read More about Spot test: new technologies bring point-of-care testing into the 21st century.

Spot test (2009)
Other

Particle facilitated testing (2008)
Patent

Impedimetric discrimination of cell types for use in a whole cell biosensor (2008)
Presentation / Conference Contribution

Paramagnetic particle detection for use with an immunoassay based biosensor (2007)
Journal Article

A biosensor and detection system that can provide measurement of analyte concentration within a test sample in four minutes is presented. The biosensor uses an immunoassay with micrometre-sized paramagnetic particle (PMP) labels for quantification. A... Read More about Paramagnetic particle detection for use with an immunoassay based biosensor.

Use of External Magnetic Fields to Reduce Reaction Times in an Immunoassay Using Micrometer-Sized Paramagnetic Particles as Labels (Magnetoimmunoassay) (2004)
Journal Article

The paper presents a rapid immunoassay system capable of quantifying analyte in complex biological and environmental media. Antibody-coated micrometer-sized paramagnetic particles are used as labels in an assay in which they bind quantitatively with... Read More about Use of External Magnetic Fields to Reduce Reaction Times in an Immunoassay Using Micrometer-Sized Paramagnetic Particles as Labels (Magnetoimmunoassay).

Magnetic field characteristics of a magneto-biosensor detection coil
Presentation / Conference Contribution

This study describes numerical modelling of a magneto-biosensor detection coil using a Boundary Element Method (BEM). The Z and X axis magnetic profiles of the coil have been analysed. The model was extended to incorporate paramagnetic particles to e... Read More about Magnetic field characteristics of a magneto-biosensor detection coil.