Use of the International Consultation on Incontinence Questionnaires bladder diary (ICIQ-BD) in men seeking therapy for lower urinary tract symptoms (LUTS)

Ito, Hiroki; Abrams, Paul; Lewis, Amanda; Young, Grace; Blair, Peter; Cotterill, Nikki; Lane, Athene; Drake, Marcus

Abstract

Background: Completion rates and correspondence to other measures need to be established for the International Consultation on Incontinence Questionnaire (ICIQ) bladder diary (ICIQ-BD) in the assessment of male lower urinary tract symptoms (LUTS). Objective: To evaluate ICIQ-BD completion rates, frequency, volume, and sensation reporting for men. Design, setting, and participants: Baseline data from the Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM) randomised controlled trial evaluating 820 men at 26 UK hospitals, looking at the ICIQ-BD, uroflowmetry, International Prostate Symptom Score, and ICIQ symptom score for male LUTS (ICIQ-MLUTS), were assessed. Outcome measurements and statistical analysis: The ICIQ-BD, IPSS, ICIQ-MLUTS, and uroflowmetry data at baseline obtained from UPSTREAM were assessed. Correlations were analysed by Pearson's correlation coefficient, and comparison between groups were performed using paired or unpaired t tests or Tukey's test. All statistical tests were two sided and the strength of evidence was presented using p values. Results and limitations: Of the participants, 25.0% (205/820) provided complete voiding and bedtime information for 3 d, 41.2% (338/820) omitted bedtime information, and the remainder omitted some or all voiding information. Median values (minimum – maximum) of 24-h, daytime, and night-time frequencies were 9.7 (3.3–24.0), 7.7 (3.3–22.7), and 1.7 (0.0–5.7), respectively. The mean voided volume per micturition for day and night times were 175.8 ± 74.2 and 264.4 ± 150.7 ml (p < 0.001), respectively. For fully completed diaries, day- and night-time frequency showed a weak-to-moderate correlation with symptom score questionnaires. More severe nocturia was generally reported in symptom scores than in the ICIQ-BD. In patients with high bother for increased daytime frequency (symptom), the mean daytime frequency (ICIQ-BD) was 9.6 ± 3.2 versus 7.6 ± 2.2 for low bother (p < 0.001). High bother for nocturia showed night-time frequency of 2.3 ± 1.2 versus 1.5 ± 1.1 for low bother (p < 0.001). For fully and partially completed diaries, ICIQ-BD sensation scores correlated weakly with symptom scores. Voided volumes from the bladder diary and uroflowmetry correlated weakly. Conclusions: Two-thirds of men (543/820) fully completed voiding information in the ICIQ-BD, but many omitted bedtime information, limiting the ability to quantify nocturia and diagnose nocturnal polyuria. Patient summary: Most men with urinary symptoms complete a bladder diary fully but may fail to indicate bedtimes. Extra information from a diary helps support symptom questionnaires to explain a patient's urinary habits.

Citation

Ito, H., Abrams, P., Lewis, A., Young, G., Blair, P., Cotterill, N., …Drake, M. (2022). Use of the International Consultation on Incontinence Questionnaires bladder diary (ICIQ-BD) in men seeking therapy for lower urinary tract symptoms (LUTS). European Urology Focus, 8(1), 66-74. https://doi.org/10.1016/j.euf.2021.12.009

• Journal Article Type: Article
• Acceptance Date: Dec 28, 2021
• Online Publication Date: Jan 10, 2022
• Publication Date: Jan 1, 2022
• Deposit Date: Jan 10, 2022
• Publicly Available Date: Jan 2, 2023
• Journal: European Urology Focus
• Electronic ISSN: 2405-4569
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 8
• Issue: 1
• Pages: 66-74
• DOI: https://doi.org/10.1016/j.euf.2021.12.009
• Public URL: https://uwe-repository.worktribe.com/output/8539361