Outputs (59)

Physical activity support for people with heart failure: mixed-methods study protocol (2025)
Journal Article

Heart failure (HF) is a common condition affecting 1-2 in every hundred adults in the UK and one in six people aged over 85 years. Physical activity is important for people with HF (PWHF) as it can increase exercise capacity and is shown to improve q... Read More about Physical activity support for people with heart failure: mixed-methods study protocol.

Baseline clinical factors associated with cessation of growth hormone therapy in patients with severe growth hormone deficiency-real world evidence (2024)
Journal Article

Background: Growth hormone replacement is indicated in adults with severe growth hormone (GH) deficiency, adult growth
hormone deficiency assessment (AGHDA) score of at least 11 and are receiving treatment for other pituitary hormone
deficiencies.... Read More about Baseline clinical factors associated with cessation of growth hormone therapy in patients with severe growth hormone deficiency-real world evidence.

Developing emotional preparedness and mental resilience through high-fidelity simulation: A ‘bridge too far’ for institutions teaching major trauma management and mass-casualty medicine? (2024)
Journal Article

Background: Clinical acumen represents only part of being adequately equipped to attend a major incident. The emotive sights, sounds and smells of these dynamic environments are all-encompassing experiences, and responders must also be armed with the... Read More about Developing emotional preparedness and mental resilience through high-fidelity simulation: A ‘bridge too far’ for institutions teaching major trauma management and mass-casualty medicine?.

Use of illness severity scores to predict mortality in interstitial lung disease patients hospitalised with acute respiratory deterioration (2023)
Journal Article

Introduction: Hospitalisations relating to acute respiratory deteriorations (ARD) in Interstitial Lung Disease (ILD) have poor outcomes. Factors predicting adverse outcomes are not fully understood and data addressing the use of illness severity scor... Read More about Use of illness severity scores to predict mortality in interstitial lung disease patients hospitalised with acute respiratory deterioration.

Developing concept system for robotics open heart surgery (2022)
Digital Artefact

Research interests in the healthcare field have for some time been growing within CFPR. A connection with Dr Muhammad Bilal from UWE’s Big Data Enterprise and Artificial Intelligence Lab is, in particular, developing some promising healthcare researc... Read More about Developing concept system for robotics open heart surgery.

Strengthening management, community engagement, and sustainability of the subnational response to accelerate malaria elimination in Namibia (2022)
Journal Article

Leadership and management skills are critical for health programs to deliver high-quality interventions in complex systems. In malaria-eliminating countries, national and subnational health teams are reorienting strategies to address focal transmissi... Read More about Strengthening management, community engagement, and sustainability of the subnational response to accelerate malaria elimination in Namibia.

Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia (2022)
Journal Article

Purpose: This study investigated the clinical determinants of mortality in hospitalized patients infected with COVID-19. Patients and Methods: A retrospective multicenter large cohort of COVID-19 patients hospitalized between March 2020 and February... Read More about Early determinants of mortality in hospitalized COVID-19 patients in the Eastern Province of Saudi Arabia.

An on-premise study to investigate the effects of mixing alcohol with caffeinated beverages (2022)
Journal Article

Objective: The purpose of this on-premise study was to determine if mixing alcohol with caffeinated mixers had an impact on objective and subjective intoxication. Methods: The study was conducted across eight drinking occasions in the City of Bristol... Read More about An on-premise study to investigate the effects of mixing alcohol with caffeinated beverages.

Automatic report-based labelling of clinical EEGs for classifier training (2022)
Presentation / Conference Contribution

Machine learning classifiers for detection of abnormal clinical electroencephalography (EEG) signals have advanced signficantly in recent years, largely supported by the carefully curated Temple University Hospital Abnormal EEG Corpus (TUAB). Further... Read More about Automatic report-based labelling of clinical EEGs for classifier training.

A comparison between ecological momentary assessment and the adapted-quick drinking screen: Alcohol mixed with energy drinks (2022)
Journal Article

AIMS: To compare alcohol consumption and risk-taking behaviours on alcohol mixed with energy drink (AMED) and alcohol-only (AO) drinking occasions collected via ecological momentary assessment (EMA) versus retrospective survey methods (adapted-Quick... Read More about A comparison between ecological momentary assessment and the adapted-quick drinking screen: Alcohol mixed with energy drinks.

Accelerometers-embedded Lycra sleeves to test wear compliance and upper limb activity in people with stroke: A feasibility study (2021)
Journal Article

Introduction To establish a possible effect of Lycra sleeves, accurate recording of wear time is critical. The aim of this study was to test whether an accelerometer-embedded Lycra sleeve can measure wear compliance and record upper-limb (UL) movemen... Read More about Accelerometers-embedded Lycra sleeves to test wear compliance and upper limb activity in people with stroke: A feasibility study.

Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected (2021)
Journal Article

Tumour microenvironments are hallmarked in many cancer types. In haematological malignancies, bone marrow (BM) mesenchymal stromal cells (MSC) protect malignant cells from drug-induced cytotoxicity. However, less is known about malignant impact on su... Read More about Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected.

How do illness perceptions influence the effectiveness of self-management in individuals living in Bermuda with type 2 diabetes? (2021)
Thesis

Diabetes is a chronic condition that occurs when blood glucose, or blood sugar, levels are too high in the body (NHS, 2016). Diabetes UK (2009) estimates that self-management is 95% of managing diabetes. Self-management refers to an individual’s abil... Read More about How do illness perceptions influence the effectiveness of self-management in individuals living in Bermuda with type 2 diabetes?.

Propofol detection for monitoring of intravenous anaesthesia: A review (2021)
Journal Article

This paper presents a review of established and emerging methods for detecting and quantifying the intravenous anaesthetic propofol in solution. There is growing evidence of numerous advantages of total intravenous anaesthesia using propofol compared... Read More about Propofol detection for monitoring of intravenous anaesthesia: A review.

Data-driven approach to COVID-19 infection forecast for Nigeria using negative binomial regression model (2021)
Book Chapter

COVID-19: the new wave of a global pandemic, is bringing about an increasing number of scientific efforts aimed at enabling governments to make informed decisions. In this paper, we explore the negative binomial regression model from the family of ge... Read More about Data-driven approach to COVID-19 infection forecast for Nigeria using negative binomial regression model.

Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects (2021)
Thesis

Advances in modern chemotherapeutic regimens have led to an increase in the overall survival of leukaemia patients in recent years. However, haematopoietic stem cell transplantation (HSCT) remains the curative option for these patients. In HSCT, high... Read More about Exploration of the possible role of microRNA(s) and small extracellular vesicles in chemotherapy-induced bystander effects.

Visual illusions modulate body perception disturbance and pain in Complex Regional Pain Syndrome: A randomized trial (2021)
Journal Article

Background: Effective treatment of longstanding Complex Regional Pain Syndrome (CRPS) is a challenge, as causal mechanisms remain elusive. People with CRPS frequently report distorted subjective perceptions of their affected limb. Evidence of pain re... Read More about Visual illusions modulate body perception disturbance and pain in Complex Regional Pain Syndrome: A randomized trial.

Patient reported outcomes in large vessel vasculitides (2021)
Journal Article

Purpose of Review: The goal of this paper is to review current and future uses of patient-reported outcomes in large vessel vasculitis. The large vessel vasculitides comprise Giant Cell Arteritis and Takayasu arteritis; both are types of systemic vas... Read More about Patient reported outcomes in large vessel vasculitides.

A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer (2020)
Journal Article

Background: Evidence for aspirin’s chemopreventative properties on colorectal cancer (CRC) is substantial, but its mechanism of action is not well-understood. We combined a proteomic approach with Mendelian randomization (MR) to identify possible new... Read More about A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer.

Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes (2020)
Presentation / Conference Contribution

Background: The five antigens of the Yt blood group system are located on the membrane GPI‐linked erythrocyte acetylcholinesterase (AChE‐E), which is implicated in a range of clinical issues, including sleep apnoea and neurotoxin poisoning. Conformat... Read More about Novel method for the measurement of erythrocyte acetylcholinesterase activity in the Yt blood group system using amperometry in conjunction with screen-printed carbon electrodes.