Patient reported outcomes in large vessel vasculitides

Robson, Joanna; Mackie, Sarah; Hill, Catherine

Abstract

Purpose of Review: The goal of this paper is to review current and future uses of patient-reported outcomes in large vessel vasculitis. The large vessel vasculitides comprise Giant Cell Arteritis and Takayasu arteritis; both are types of systemic vasculitis which affect the larger blood vessels. Patient-reported outcomes (PROs) capture the impact of these diseases on health-related quality of life. Recent Findings: Generic PROs such as the SF-36 are currently used to compare HRQOL of people with GCA and TAK within clinical trials and observational studies and to make comparisons with the general population and HRQoL in other diseases. The development of a disease-specific PRO for GCA is currently underway. Beyond clinical trials, there is much interest in the use of PROs within routine clinical care, particularly E-PROs for remote use. Summary: Further work will be needed to complete the development of disease-specific PROs for people with large vessel vasculitis and to establish feasibility, acceptability, and utility of E-PROs.

• Journal Article Type: Review
• Acceptance Date: Dec 18, 2020
• Online Publication Date: Jan 28, 2021
• Publication Date: Feb 1, 2021
• Deposit Date: Dec 18, 2020
• Publicly Available Date: Feb 8, 2021
• Journal: Current Rheumatology Reports
• Print ISSN: 1523-3774
• Electronic ISSN: 1534-6307
• Publisher: Springer (part of Springer Nature)
• Peer Reviewed: Peer Reviewed
• Volume: 23
• Issue: 2
• Article Number: 7
• DOI: https://doi.org/10.1007/s11926-020-00979-4
• Keywords: Giant cell arteritis; Takayasu arteritis; Patient reported outcome; Clinical trials; Outcomes; Large vessel vasculitis
• Public URL: https://uwe-repository.worktribe.com/output/6959563