Outputs (10)

Validation of a sensor system for the measurement of breath ammonia using selected-ion flow-tube mass spectrometry (2024)
Journal Article

The measurement of trace breath gases is of growing interest for its potential to provide non-invasive physiological information in health and disease. While instrumental techniques such as selected-ion flow-tube mass spectrometry (SIFT-MS) can achie... Read More about Validation of a sensor system for the measurement of breath ammonia using selected-ion flow-tube mass spectrometry.

Identifying targetable metabolic dependencies across colorectal cancer progression (2024)
Journal Article

Colorectal cancer (CRC) is a multi-stage process initiated through the formation of a benign adenoma, progressing to an invasive carcinoma and finally metastatic spread. Tumour cells must adapt their metabolism to support the energetic and biosynthet... Read More about Identifying targetable metabolic dependencies across colorectal cancer progression.

Spliceosomal vulnerability of MYCN-amplified neuroblastoma is contingent on PRMT5-mediated regulation of epitranscriptomic and metabolomic pathways (2024)
Journal Article

Approximately 50% of poor prognosis neuroblastomas arise due to MYCN over-expression. We previously demonstrated that MYCN and PRMT5 proteins interact and PRMT5 knockdown led to apoptosis of MYCN amplified (MNA) neuroblastoma. Here we evaluate the hi... Read More about Spliceosomal vulnerability of MYCN-amplified neuroblastoma is contingent on PRMT5-mediated regulation of epitranscriptomic and metabolomic pathways.

Video gaming and sleep in adults: A systematic review (2024)
Journal Article

Video games (VGs) are one of the most common forms of entertainment and their diffusion is constantly increasing. Although largely studied in the framework of their relationship with mental and physical health, the relationship of VGs with sleep are... Read More about Video gaming and sleep in adults: A systematic review.

The peer review process: Past, present, and future (2024)
Journal Article

The peer review process is a fundamental aspect of modern scientific paper publishing, underpinning essential quality control. First conceptualised in the 1700s, it is an iterative process that aims to elevate scientific literature to the highest sta... Read More about The peer review process: Past, present, and future.

Effectiveness of infection prevention and control interventions in health care facilities in Africa: A systematic review (2024)
Journal Article

Background Healthcare associated infections (HAIs) are a major threat to patient safety and quality care. However, they are avoidable by implementing evidence-based infection prevention and control measures. This re... Read More about Effectiveness of infection prevention and control interventions in health care facilities in Africa: A systematic review.

An evaluation of blood transfusion service in Saudi Arabia (2024)
Thesis

Background: Blood transfusion is needed to support the care given to many medical and surgical patients, and can reduce morbidity and mortality. The blood transfusion service (BTS) in the Kingdom of Saudi Arabia (KSA) is hospital-based. This study ai... Read More about An evaluation of blood transfusion service in Saudi Arabia.

Editorial: The RNA revolution and cancer (2024)
Journal Article

RNA biology has revolutionized cancer understanding and treatment, especially in endocrine-related malignancies. This editorial highlights RNA's crucial role in cancer progression, emphasizing its influence on tumor heterogeneity and behavior. Proces... Read More about Editorial: The RNA revolution and cancer.

The effects of glucose supplementation on the development of Acinetobacter baumannii biofilms (2024)
Presentation / Conference Contribution

The Effect of Glucose on The Development of Acinetobacter baumannii Biofilm

Background: Acinetobacter baumannii, is an opportunistic pathogen causing pneumonia, bacteraemia, wound and urinary tract infections with high mortality rates due to multi... Read More about The effects of glucose supplementation on the development of Acinetobacter baumannii biofilms.

Understanding the chemotherapy-induced bystander effect; an evaluation of the role of cytokine storm in an in-vitro model of the human bone marrow (2024)
Thesis

The phenomenon of donor cell leukaemia (DCL) occurs following haematopoietic stem cell transplantation (HSCT), but its aetiology is currently unknown. Previous work within the research group identified a chemotherapy-induced bystander effect (CIBE) i... Read More about Understanding the chemotherapy-induced bystander effect; an evaluation of the role of cytokine storm in an in-vitro model of the human bone marrow.