Using research-based learning to enhance doctoral skills development
(2014)
Journal Article
All Outputs (104)
Molecular dynamics simulation of humic substances (2014)
Journal Article
© 2014, Orsi. Humic substances (HS) are complex mixtures of natural organic material which are found almost everywhere in the environment, and particularly in soils, sediments, and natural water. HS play key roles in many processes of paramount impor... Read More about Molecular dynamics simulation of humic substances.
Convergence of vitamin D and lysophosphatidic acid signaling in stimulating human osteoblast maturation (2014)
Journal Article
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Adrenomedullin and Glucocorticoids interaction at the glial/endothelial interface: two sides of the same regulatory coin? (2014)
Journal Article
Adrenomedullin is a vasodilatatory peptide, important during the inflammation process and also able to regulate blood-brain barrier function. Adrenomedullin and its receptors have been shown to be glucocorticoid-dependent in many cell types, includin... Read More about Adrenomedullin and Glucocorticoids interaction at the glial/endothelial interface: two sides of the same regulatory coin?.
Hydrogen sulfide and cell signaling: Team player or referee? (2014)
Journal Article
Hydrogen sulfide (H2S) has been postulated to be the third gasotransmitter, and along with other reactive compounds such as reactive oxygen species (ROS) and nitric oxide (NO) it is thought to be a key signalling molecule. Enzymes which generate H2S,... Read More about Hydrogen sulfide and cell signaling: Team player or referee?.
The building as an exhibit: Communicating environmental sustainability in science centres (2014)
Book Chapter
This paper is based on research carried out by Jennifer Garret as part of her MSc in Science Communication
Encouraging creativity: Novel learning environments in science and technology centres (2014)
Book Chapter
This paper is based on research carried out by Melanie Davies as part of her MSc in Science Communication
'More dynamic than expected': Assessing STFC Rutherford Appleton Laboratory's work experience placements (2014)
Book Chapter
This paper is based on research carried out by Alexander Brown as part of his MSc in Science Communication
Human osteoblast growth and maturation in response to metformin and the thienopyridone, A769662 (2014)
Journal Article
Metformin (Met) is a biguanide drug widely used in the treatment and management of non insulin-dependent diabetes mellitus. In recent years it has emerged that Met, by stimulating adenosine monophosphate-activated protein kinase (AMPK), can promote t... Read More about Human osteoblast growth and maturation in response to metformin and the thienopyridone, A769662.
Rapid in-vitro testing for chemotherapy sensitivity in leukaemia patients (2014)
Journal Article
© Springer-Verlag Berlin Heidelberg 2014. Bioluminescent bacterial biosensors can be used in a rapid in vitro assay to predict sensitivity to commonly used chemotherapy drugs in acute myeloid leukemia (AML). The nucleoside analog cytarabine (ara-C) i... Read More about Rapid in-vitro testing for chemotherapy sensitivity in leukaemia patients.
In this study, we investigate the potential for oral Lactobacilli (LB) to afford innate protection against nasopharyngeal coloniser Neisseria meningitidis serogroup B (NmB), which causes the bulk of UK meningococcal disease. Oral isolates of L. plant... Read More about Oral Lactobacillus plantarum NCIMB 8825 inhibits adhesion, invasion and metabolism of Neisseria meningitidis serogroup B and affords anti-inflammatory and cytotoxic protection to nasopharyngeal epithelial cells.
A review of the volatiles from the healthy human body (2014)
Journal Article
A compendium of all the volatile organic compounds (VOCs) emanating from the human body (the volatolome) is for the first time reported. 1840 VOCs have been assigned from breath (872), saliva (359), blood (154), milk (256), skin secretions (532) urin... Read More about A review of the volatiles from the healthy human body.
Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correl (2014)
Journal Article
Recent restrictions on the testing of cosmetic ingredients in animals have resulted in the need to test the genotoxic potential of chemicals exclusively in vitro prior to licensing. However, as current in vitro tests produce some misleading positive... Read More about Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correl.
The use of a gas chromatograph coupled to a metal oxide sensor for rapid assessment of stool samples from irritable bowel syndrome and inflammatory bowel disease patients (2014)
Journal Article
There is much clinical interest in the development of a low-cost and reliable test for diagnosing inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), two very distinct diseases that can present with similar symptoms. The assessment o... Read More about The use of a gas chromatograph coupled to a metal oxide sensor for rapid assessment of stool samples from irritable bowel syndrome and inflammatory bowel disease patients.
Towards point of care testing for C. difficile infection by volatile profiling, using the combination of a short multi-capillary gas chromatography column with metal oxide sensor detection (2014)
Journal Article
Rapid volatile profiling of stool sample headspace was achieved using a combination of short multi-capillary chromatography column (SMCC), highly sensitive heated metal oxide semiconductor sensor and artificial neural network software. For direct ana... Read More about Towards point of care testing for C. difficile infection by volatile profiling, using the combination of a short multi-capillary gas chromatography column with metal oxide sensor detection.
Review: 'Social networks and popular understanding of science and health: sharing disparities' by Brian G Southwell (2014)
Journal Article
In this book, Brian G Southwell discusses how disparities in information-sharing arise and what can be done to alleviate them. In all sorts of ways and for all sorts of reasons, people have always sought to share information among their family and ot... Read More about Review: 'Social networks and popular understanding of science and health: sharing disparities' by Brian G Southwell.
Microbial acetone oxidation in coastal seawater (2014)
Journal Article
Acetone is an important oxygenated volatile organic compound (OVOC) in the troposphere where it influences the oxidizing capacity of the atmosphere. However, the air-sea flux is not well quantified, in part due to a lack of knowledge regarding which... Read More about Microbial acetone oxidation in coastal seawater.
Peering over the shoulders of giants? (2014)
Journal Article
‘Open’ is a highly-visible cultural trend of the early twenty-first century. A brief scan of a
newspaper or quick Internet search reveals it as a prefix to learning, source, standard, data,
knowledge, democracy, access, repository, innovation, gove... Read More about Peering over the shoulders of giants?.
Comparison of the kinetic performance and retentivity of sub-2μm core-shell, hybrid and conventional bare silica phases in hydrophilic interaction chromatography (2014)
Journal Article
© 2014 Elsevier B.V. The separation performance and retention properties of four sub-2μm underivatised silica materials were evaluated in the hydrophilic interaction chromatography (HILIC) mode. These included an organic/inorganic hybrid silica, conv... Read More about Comparison of the kinetic performance and retentivity of sub-2μm core-shell, hybrid and conventional bare silica phases in hydrophilic interaction chromatography.