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All Outputs (463)

Integrating multi-omics data with deep learning for predictive modelling of autoimmune and neurodegenerative diseases (2025)
Presentation / Conference Contribution

In precision medicine, predicting the onset and progression of autoimmune and neurodegenerative diseases poses a multifaceted challenge due to their intricate molecular complexities. Traditional diagnostic methods, while foundational, often fall shor... Read More about Integrating multi-omics data with deep learning for predictive modelling of autoimmune and neurodegenerative diseases.

Enhanced heart sound classification using Mel frequency cepstral coefficients and comparative analysis of single vs. ensemble classifier strategies (2024)
Journal Article

This paper seeks to enhance the performance of Mel Frequency Cepstral Coefficients (MFCCs) for detecting abnormal heart sounds. Heart sounds are first pre-processed to remove noise and then segmented into S1, systole, S2, and diastole intervals, with... Read More about Enhanced heart sound classification using Mel frequency cepstral coefficients and comparative analysis of single vs. ensemble classifier strategies.

Stress reactivity moderates the association between stressful life events and depressive symptoms in adolescents: Results from a population-based study (2024)
Journal Article

A large body of evidence links stressful life events with depression. However, little is understood about the role of perceived impact in this association. We performed regression analysis to investigate whether self-reported stress reactivity (deriv... Read More about Stress reactivity moderates the association between stressful life events and depressive symptoms in adolescents: Results from a population-based study.

History-enhanced ICT For Sustainability education: Learning together with Business Computing students (2024)
Presentation / Conference Contribution

his research explores the use of History to enhance education in the field of ICT For Sustainability (ICT4S) in response to a challenge from the ICT4S 2023 conference. No previous studies were found in ICT4S but the literature on History and Educatio... Read More about History-enhanced ICT For Sustainability education: Learning together with Business Computing students.

Clinical and patient-reported outcomes in women offered oncoplastic breast conserving surgery as an alternative to mastectomy in the ANTHEM multicentre, prospective cohort study (2024)
Journal Article

ABSTRACT

Background: Oncoplastic breast conserving surgery (OPBCS) may be a better option than mastectomy, but high-quality comparative evidence is lacking. The ANTHEM study (ISRCTN18238549) aimed to explore clinical and patient-reported outcomes... Read More about Clinical and patient-reported outcomes in women offered oncoplastic breast conserving surgery as an alternative to mastectomy in the ANTHEM multicentre, prospective cohort study.

Maximizing insights from longitudinal epigenetic age data: Simulations, applications, and practical guidance (2024)
Journal Article

Background: Epigenetic age (EA) is an age estimate, developed using DNA methylation (DNAm) states of selected CpG sites across the genome. Although EA and chronological age are highly correlated, EA may not increase uniformly with time. Departures, k... Read More about Maximizing insights from longitudinal epigenetic age data: Simulations, applications, and practical guidance.

Evaluating the effectiveness and acceptability of two positive body image media micro-interventions among children aged 4–6 years old – a study protocol (2024)
Journal Article

Background: Children’s online media perpetuates appearance idealised images and can negatively impact the way children feel about their own and other people’s bodies (e.g., weight bias) at a young age. The development and evaluation of body image int... Read More about Evaluating the effectiveness and acceptability of two positive body image media micro-interventions among children aged 4–6 years old – a study protocol.

Understanding the emergency medical service response to patients who are at imminent risk of out-of-hospital cardiac arrest (2024)
Journal Article

Study Aim: To understand the survival and emergency medical service call triage and response to patients who suffer an out-of-hospital cardiac arrest after the emergency medical service call is connected.
Methods: A descriptive retrospective data a... Read More about Understanding the emergency medical service response to patients who are at imminent risk of out-of-hospital cardiac arrest.