Investigating the efficacy of the bacteriophage vB_PaeM_SM against a bioluminescent strain of Pseudomonas aeruginosa in a biofilm and planktonic model
(2020)
Presentation / Conference Contribution
All Outputs (13)
Prevalence of Carbapenemase Producing Organisms in East London, UK. (2019)
Presentation / Conference Contribution
Carbapenemases are enzymes, produced by an array of common Gram-negative organisms, which hydrolyse the carbapenem antibiotics, conferring resistance [1]. The main protagonists are the “big five” carbapenemases, KPC, OXA-48, IMP, VIM and NDM, which h... Read More about Prevalence of Carbapenemase Producing Organisms in East London, UK..
Point prevalence study determining the inpatient rate of carbapenemase-producing organisms at a large NHS trust in the UK (2019)
Presentation / Conference Contribution
A point prevalence study (PPS) to determine the carriage rate of carbapenemase producing organisms (CPOs) was performed across 4 sites at Barts Health NHS Trust (BHT), encompassing 2.5 million patients across three London boroughs: Tower Hamlets, New... Read More about Point prevalence study determining the inpatient rate of carbapenemase-producing organisms at a large NHS trust in the UK.
Community screening to determine the prevalence of carbapenemase producing organisms in East London, 2018 (2018)
Presentation / Conference Contribution
Carbapenems are broad spectrum antibiotics reserved for patients who are extremely ill or suspected of having an infection caused by a multidrug resistant organism (Nordmann et al., 2011). Over the past ten years there has been a dramatic increase in... Read More about Community screening to determine the prevalence of carbapenemase producing organisms in East London, 2018.
Isolation and characterisation of bacteriophages for use against biofilms of Pseudomonas aeruginosa clinical isolates (2018)
Presentation / Conference Contribution
Pseudomonas aeruginosa is a World Health Organization priority 1, ESKAPE pathogen that is capable of causing a wide spectrum of nosocomial and community-acquired infections. It employs a wide range of antibiotic resistance mechanisms and is often dif... Read More about Isolation and characterisation of bacteriophages for use against biofilms of Pseudomonas aeruginosa clinical isolates.
Characterisation of a dual species perfusion biofilm model (2018)
Presentation / Conference Contribution
An estimated 65–80% of human infections are biofilm-related. As the biofilm mode of growth significantly contributes to bacterial tolerance of antimicrobial treatment, this has important ramifications for patient morbidity and associated healthcare c... Read More about Characterisation of a dual species perfusion biofilm model.
Validation of real-time PCR targeting the ‘Big five’ carbapenemases (2017)
Presentation / Conference Contribution
Poster presentation
Dual species biofilm culture of Staphylococcus aureus and a bioluminescent strain of Pseudomonas aeruginosa (2016)
Presentation / Conference Contribution
Poster presentation.
Introduction
Pseudomonas aeruginosa and Staphylococcus aureus are significant pathogens of wounds and the cystic fibrosis lung. There are likely to be complex interactions between the two species, with biofilm co-culture aff... Read More about Dual species biofilm culture of Staphylococcus aureus and a bioluminescent strain of Pseudomonas aeruginosa.
Modelling the effects of pH on tongue biofilm using Sorbarod Biofilm Perfusion System (2009)
Presentation / Conference Contribution
Daptomycin and Gentamicin Show Limited Activity in a Novel In Vitro Model of Osteomyelitis (2008)
Presentation / Conference Contribution
Investigation of the probiotic effects of Escherichia coli Nissle 1917 using a whole cell bioluminescent bacterial biosensor (2008)
Presentation / Conference Contribution
In a novel, in vitro, model of osteomyelitis, Staphylococcus aureus biofilms are resistant to gentamicin and daptomycin at clinically relevant concentrations (2008)
Presentation / Conference Contribution
Prevalence of Carbapenemase Producing Organisms in East London, UK
Presentation / Conference Contribution
Carbapenemases are enzymes, produced by an array of common Gram-negative organisms, which hydrolyse the carbapenem antibiotics, conferring resistance. The main protagonists are the “big five” carbapenemases, KPC, OXA-48, IMP, VIM and NDM, which have... Read More about Prevalence of Carbapenemase Producing Organisms in East London, UK.