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Ian Wilson


Abscisic acid induced a negative geotropic response in dark-incubated Chlamydomonas reinhardtii (2019)
Journal Article
Wilson, I., Ladomery, M., Macdonald, H., Al-Hijab, L., Gregg, A., & Davies, R. (2019). Abscisic acid induced a negative geotropic response in dark-incubated Chlamydomonas reinhardtii. Scientific Reports, 9, https://doi.org/10.1038/s41598-019-48632-0

The phytohormone abscisic acid (ABA) plays a role in stresses that alter plant water status and may also regulate root gravitropism and hydrotropism. ABA also exists in the aquatic algal progenitors of land plants, but other than its involvement in s... Read More about Abscisic acid induced a negative geotropic response in dark-incubated Chlamydomonas reinhardtii.

The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties (2018)
Journal Article
Jumbe, S., Porazinski, S., Oltean, S., Mansell, J., Vahabi, B., Wilson, I., & Ladomery, M. (2019). The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties. Translational Oncology, 12(1), 134-142. https://doi.org/10.1016/j.tranon.2018.09.001

© 2018 The oncogene ERG encodes an ETS family transcription factor and is implicated in blood, vascular, and bone development and in prostate, blood, and bone cancer. The ERG gene is alternatively spliced; of particular interest is its cassette exon... Read More about The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties.

Suppression of the in vitro growth and development of Microdochium nivale by phosphite (2018)
Journal Article
Dempsey, J., Wilson, I. D., Spencer-Phillips, P., & Arnold, D. L. (2018). Suppression of the in vitro growth and development of Microdochium nivale by phosphite. Plant Pathology, 67(6), 1296-1306. https://doi.org/10.1111/ppa.12846

© 2018 British Society for Plant Pathology The ascomycete fungus Microdochium nivale is a major pathogen of many species of the gramineae. Control measures rely heavily on chemical fungicides, making alternative means of disease reduction desirable.... Read More about Suppression of the in vitro growth and development of Microdochium nivale by phosphite.

Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention (2018)
Journal Article
Uzor, S., Zorzou, P., Bowler, E., Porazinski, S., Wilson, I. D., & Ladomery, M. (2018). Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention. Gene, 670, 46-54. https://doi.org/10.1016/j.gene.2018.05.095

© 2018 Elsevier B.V. Alternative splicing is a key process required for the regulation of gene expression in normal development and physiology. It is regulated by splice factors whose activities are in turn regulated by splice factor kinases and phos... Read More about Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention.

Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells (2018)
Journal Article
Bowler, E., Porazinski, S., Uzor, S., Thibault, P., Durand, M., Lapointe, E., …Ladomery, M. (2018). Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells. BMC Cancer, 18(1), 355. https://doi.org/10.1186/s12885-018-4227-7

© 2018 The Author(s). Background: Mounting evidence suggests that one of the ways that cells adapt to hypoxia is through alternative splicing. The aim of this study was firstly to examine the effect of hypoxia on the alternative splicing of cancer as... Read More about Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells.

Residual ground-water levels of the neonicotinoid thiacloprid perturb chemosensing of Caenorhabditis elegans (2017)
Journal Article
Floyd, K. G., Hopewell, H., Burnell, D., Hancock, J. T., Allainguillaume, J., Ladomery, M., & Wilson, I. D. (2017). Residual ground-water levels of the neonicotinoid thiacloprid perturb chemosensing of Caenorhabditis elegans. Ecotoxicology, 26(7), 981-990. https://doi.org/10.1007/s10646-017-1826-z

© 2017, The Author(s). This study investigated the neurological effects of residual ground-water levels of thiaclopridon the non-target organism Caenorhabditis elegans. Nematodes treated with thiacloprid showed a dose-dependent and significantly incr... Read More about Residual ground-water levels of the neonicotinoid thiacloprid perturb chemosensing of Caenorhabditis elegans.

The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells (2017)
Journal Article
Ladomery, M. R., Wilson, I., Adamo, P., Porazinski, S., Rajatileka, S., Jumbe, S., …Ladomery, M. (2017). The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells. Oncology Letters, 14(5), 5605-5610. https://doi.org/10.3892/ol.2017.6841

© 2017, Spandidos Publications. All rights reserved. The oncogene ETS-related gene (ERG) encodes a transcription factor with roles in the regulation of haematopoiesis, angiogenesis, vasculogenesis, inflammation, migration and invasion. The ERG oncoge... Read More about The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells.

Elevated CO2-Induced Responses in Stomata Require ABA and ABA Signaling (2015)
Journal Article
Hetherington, A. M., Gray, J. E., Neill, S. J., Wilson, I., Isner, J. C., McLachlan, D. H., …Hetherington, A. (2015). Elevated CO2-Induced Responses in Stomata Require ABA and ABA Signaling. Current Biology, 25(20), 2709-2716. https://doi.org/10.1016/j.cub.2015.09.013

© 2015 The Authors. An integral part of global environment change is an increase in the atmospheric concentration of CO2 ([CO2]) [1]. Increased [CO2] reduces leaf stomatal apertures and density of stomata that plays out as reductions in evapotranspir... Read More about Elevated CO2-Induced Responses in Stomata Require ABA and ABA Signaling.

Detection of thiol modifications by hydrogen sulfide (2015)
Book Chapter
Williams, E., Pead, S., Whiteman, M., Wood, M. E., Wilson, I. D., Ladomery, M., …Hancock, J. T. (2015). Detection of thiol modifications by hydrogen sulfide. In E. Cadenas, & L. Packer (Eds.), Hydrogen Sulfide in Redox Biology Part B, 233-251. Academic Press

The evolutionarily conserved multifunctional glycine-rich RNA-binding proteins play key roles in development and stress adaptation (2015)
Journal Article
Wilson, I., Hancock, J., Ciuzan, O., Hancock, J. T., Pamfil, D., Wilson, I. D., & Ladomery, M. (2015). The evolutionarily conserved multifunctional glycine-rich RNA-binding proteins play key roles in development and stress adaptation. Physiologia Plantarum, 153(1), 1-11. https://doi.org/10.1111/ppl.12286

© 2014 Scandinavian Plant Physiology Society. The class IV glycine-rich RNA-binding proteins are a distinct subgroup within the heterogenous superfamily of glycine-rich proteins (GRPs). They are distinguished by the presence of an RNA-binding domain... Read More about The evolutionarily conserved multifunctional glycine-rich RNA-binding proteins play key roles in development and stress adaptation.

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