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Energy harvesting from plants using hybrid microbial fuel cells; potential applications and future exploitation (2024)
Journal Article
Greenman, J., Thorn, R., Willey, N., & Ieropoulos, I. (2024). Energy harvesting from plants using hybrid microbial fuel cells; potential applications and future exploitation. Frontiers in Bioengineering and Biotechnology, 12, Article 1276176. https://doi.org/10.3389/fbioe.2024.1276176

Microbial Fuel Cells (MFC) can be fuelled using biomass derived from dead plant material and can operate on plant produced chemicals such as sugars, carbohydrates, polysaccharides and cellulose, as well as being “fed” on a regular diet of primary bio... Read More about Energy harvesting from plants using hybrid microbial fuel cells; potential applications and future exploitation.

Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells (2023)
Journal Article
Robson, J. L., Thorn, R. M. S., Williams, A. C., Collard, T. J., & Qualtrough, D. (2023). Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells. Scientific Reports, 13(1), Article 17291. https://doi.org/10.1038/s41598-023-44130-6

Colorectal cancer (CRC) is a significant global health burden with a rising incidence worldwide. Distinct bacterial populations are associated with CRC development and progression, and it is thought that the relationship between CRC and associated gu... Read More about Gut bacteria promote proliferation in benign S/RG/C2 colorectal tumour cells, and promote proliferation, migration and invasion in malignant HCT116 cells.

The control of pathogens in stored rainwater using direct electrochemical activation (2022)
Conference Proceeding
Clayton, G., Fox, B., Steer, M., Thorn, R., & Reynolds, D. (2022). The control of pathogens in stored rainwater using direct electrochemical activation. In IWRA Proceedings

Purpose of study or research hypothesis: The main study aim was to control waterborne pathogens using small-scale direct electrochemical activation. Key issue(s) or problem(s) addressed: Rainwater harvesting systems enable households o... Read More about The control of pathogens in stored rainwater using direct electrochemical activation.

Clean water for all (2022)
Digital Artefact
Clayton, G., Steven, J., Thorn, R., & Reynolds, D. (2022). Clean water for all. [Website]

The World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF) estimated that, as of 2020, 2 billion people across the globe did not have access to safely managed drinking water. Ideally, safely managed drinking water should b... Read More about Clean water for all.

Managing potential pathogens in stored rainwater using small-scale in-situ electrochemical activation (2022)
Presentation / Conference
Clayton, G., Fox, B., Steer, M., Thorn, R., & Reynolds, D. (2022, September). Managing potential pathogens in stored rainwater using small-scale in-situ electrochemical activation. Presented at International Water Association World Water Congress and Exhibition, Copenhagen

Rainwater can be a lifeline for many people who do not have piped water supplies, experience dry seasons, or live-in fresh water scarce areas. The quality of stored rainwater can deteriorate over time, due to increasing concentrations of contaminants... Read More about Managing potential pathogens in stored rainwater using small-scale in-situ electrochemical activation.

The control of waterborne pathogenic bacteria in fresh water using a biologically active filter (2022)
Journal Article
Steven, J. A. C., Thorn, R. M. S., Robinson, G. M., Turner, D., Lee, J. E., & Reynolds, D. M. (2022). The control of waterborne pathogenic bacteria in fresh water using a biologically active filter. npj Clean Water, 5(1), 30. https://doi.org/10.1038/s41545-022-00169-y

The aim of this study was to investigate the control of three species of bacteria commonly associated with biologically contaminated water, using biofiltration. In this study, a laboratory-scale biofilter system was used to investigate the control of... Read More about The control of waterborne pathogenic bacteria in fresh water using a biologically active filter.

A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India (2022)
Journal Article
Fox, B., Thorn, R., Dutta, T., Bowes, M., Read, D., & Reynolds, D. (2022). A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India. Science of the Total Environment, 842, 156848. https://doi.org/10.1016/j.scitotenv.2022.156848

The quality and health of many of our vital freshwater systems are poor. To tackle this with ever increasing pressures from anthropogenic and climatic changes, we must improve water quality monitoring and devise and implement more appropriate water q... Read More about A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India.

The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model (2022)
Journal Article
Perrin, E. M., Thorn, R. M., Sargeant, S. L., Attridge, J. W., & Reynolds, D. M. (2022). The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model. Frontiers in Microbiology, 13, Article 817976. https://doi.org/10.3389/fmicb.2022.817976

Dissolved organic matter (DOM) is ubiquitous throughout aquatic systems. Fluorescence techniques can be used to characterize the fluorescing proportion of DOM, aquatic fluorescent organic matter (AFOM). AFOM is conventionally named in association wit... Read More about The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model.

The efficacy of chlorine-based disinfectants against planktonic and biofilm bacteria for decentralised point-of-use drinking water (2021)
Journal Article
Clayton, G. E., Thorn, R., & Reynolds, D. (2021). The efficacy of chlorine-based disinfectants against planktonic and biofilm bacteria for decentralised point-of-use drinking water. npj Clean Water, 4(1), Article 48. https://doi.org/10.1038/s41545-021-00139-w

Chlorine solutions are used extensively for the production of biologically safe drinking water. The capability of point-of-use [POU] drinking water treatment systems has gained interest in locations where centralised treatment systems and distributio... Read More about The efficacy of chlorine-based disinfectants against planktonic and biofilm bacteria for decentralised point-of-use drinking water.

Real-time detection of volatile metabolites enabling species-level discrimination of bacterial biofilms associated with wound infection (2021)
Journal Article
Slade, E., Thorn, R., Young, A., & Reynolds, D. (2022). Real-time detection of volatile metabolites enabling species-level discrimination of bacterial biofilms associated with wound infection. Journal of Applied Microbiology, 132(3), 1558-1572. https://doi.org/10.1111/jam.15313

Aims: The main aim of this study was to investigate the real-time detection of volatile metabolites for the species-level discrimination of pathogens associated with clinically relevant wound infection, when grown in a collagen wound biofilm model. M... Read More about Real-time detection of volatile metabolites enabling species-level discrimination of bacterial biofilms associated with wound infection.

Laboratory in-situ production of autochthonous and allochthonous fluorescent organic matter by freshwater bacteria (2021)
Journal Article
Fox, B. G., Thorn, R. M. S., & Reynolds, D. M. (2021). Laboratory in-situ production of autochthonous and allochthonous fluorescent organic matter by freshwater bacteria. Microorganisms, 9(8), Article 1623. https://doi.org/10.3390/microorganisms9081623

This work investigates the origin and range of fluorescent organic matter (FOM) produced in-situ by environmentally sourced freshwater bacteria. Aquatic FOM is an essential component in global carbon cycling and is generally classified as either auto... Read More about Laboratory in-situ production of autochthonous and allochthonous fluorescent organic matter by freshwater bacteria.

Sediment and surface water microplastic contamination along the Ganges River, from the Himalayan foothills to the tidal reach downstream of Kolkata, India (2021)
Presentation / Conference
Nel, H., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Sediment and surface water microplastic contamination along the Ganges River, from the Himalayan foothills to the tidal reach downstream of Kolkata, India. Presented at EGU General Assembly 2021

Twenty rivers have been estimated previously to account for almost 70% of global plastic emissions to the marine environment. Of these, the Ganges River was second only to the Yangtze River. Yet, scale and complexity of the Ganges River network make... Read More about Sediment and surface water microplastic contamination along the Ganges River, from the Himalayan foothills to the tidal reach downstream of Kolkata, India.

Taking the pulse of Mother Ganga - Revealing the visible and invisible water pollution crisis along the Ganges River (2021)
Presentation / Conference
Krause, S., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Taking the pulse of Mother Ganga - Revealing the visible and invisible water pollution crisis along the Ganges River. Presented at EGU General Assembly 2021

It is probably hard to overestimate the significance of the River Ganges for its spiritual, cultural and religious importance. As the worlds’ most populated river basin and a major water resource for the 400 million people inhabiting its catchment, t... Read More about Taking the pulse of Mother Ganga - Revealing the visible and invisible water pollution crisis along the Ganges River.

Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin (2021)
Presentation / Conference
Khamis, K., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin. Presented at EGU General Assembly 2021

There is increasing interest in monitoring spatial variability in biogeochemical processes using field deployable sensors. Despite this, rigorous assessments of accuracy and optimal sensor configurations remain limited for such applications. We under... Read More about Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin.

Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts (2021)
Presentation / Conference
Richards, L. A., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts. Presented at EGU General Assembly 2021

In a basin-wide survey of the River Ganga and key tributaries, from the Himalayan source to the Bay of Bengal in India, we aim to improve the conceptual understanding of downstream water quality trends along > 2000 km. Here we explore the spatial di... Read More about Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts.

A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India (2021)
Presentation / Conference
Fox, B., Thorn, R., Dutta, T., & Reynolds, D. (2021, April). A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India. Presented at EGU General Assembly 2021

With increasing pressures on water resources due to population, industrialization, agriculture, urbanization and climatic changes, improved temporal and spatial understanding of water quality is required. The development of new monitoring parameters,... Read More about A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India.

Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms (2020)
Conference Proceeding
Clayton, G., Thorn, R., & Reynolds, D. (in press). Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms

Summary of key findings Direct disinfection of established Pseudomonas aeruginosa biofilms by electrochemically activated solutions [ECAS] exhibited significantly greater anti-biofilm activity compared to NaOCl and HOCl at free chlorine concentratio... Read More about Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms.

The metabolic profiles and bacterial interactions of Bacteroides fragilis, Salmonella enterica serovar Typhimurium, E. coli Nissle 1917 and Clostridium perfringens on RG/C2 (benign) and HCT116 (malignant) colorectal tumour cell lines (2020)
Presentation / Conference
Okeyoyin, R., Robin, T., & David, Q. (2020, July). The metabolic profiles and bacterial interactions of Bacteroides fragilis, Salmonella enterica serovar Typhimurium, E. coli Nissle 1917 and Clostridium perfringens on RG/C2 (benign) and HCT116 (malignant) colorectal tumour cell lines. Presented at School of Applied Sciences Master of Research Conference, University of the West of England (UWE), Bristol, UK

The aim of this research was to determine the interaction of the afore mentioned bacterial species on the attachment and invasion of both benign and malignant tumour cells using the gentamicin and metronidazole bacterial infection assay. The results... Read More about The metabolic profiles and bacterial interactions of Bacteroides fragilis, Salmonella enterica serovar Typhimurium, E. coli Nissle 1917 and Clostridium perfringens on RG/C2 (benign) and HCT116 (malignant) colorectal tumour cell lines.

An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics (2019)
Journal Article
Slade, E. A., Thorn, R. M. S., Young, A., & Reynolds, D. M. (2019). An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics. BMC Microbiology, 19(1), Article 310. https://doi.org/10.1186/s12866-019-1682-5

Background The majority of in vitro studies of medically relevant biofilms involve the development of biofilm on an inanimate solid surface. However, infection in vivo consists of biofilm growth on, or suspended within, the semi-solid matrix of the... Read More about An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics.

Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment (2019)
Journal Article
Fraser, M., Borman, A. M., Thorn, R., & Lawrance, L. M. (2020). Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment. Medical Mycology, 58(2), 219-226. https://doi.org/10.1093/mmy/myz053

Candidaemia is widely reported as the fourth most common form of bloodstream infection worldwide. Reports of breakthrough cases of candidaemia are increasing, especially in the context of a move away from azole antifungals as prophylactic or first li... Read More about Resistance to echinocandin antifungal agents in the United Kingdom in clinical isolates of Candida glabrata: Fifteen years of interpretation and assessment.

Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment (2019)
Journal Article
Clayton, G. E., Thorn, R. M., & Reynolds, D. M. (2019). Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment. Frontiers in Environmental Science, 7, Article 35. https://doi.org/10.3389/fenvs.2019.00035

© 2019 Clayton, Thorn and Reynolds. Point-of-use (POU) drinking water treatment systems provide solutions for communities where centralized facilities are unavailable. Effective POU systems treat and reduce the number of pathogens in POU water suppl... Read More about Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment.

Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system (2018)
Journal Article
Fox, B. G., Thorn, R. M., Anesio, A. M., Cox, T., Attridge, J. W., & Reynolds, D. M. (2019). Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system. Water, 11(1), Article 10. https://doi.org/10.3390/w11010010

© 2018 by the authors. Organic matter (OM) has an essential biogeochemical influence along the hydrological continuum and within aquatic ecosystems. Organic matter derived via microbial processes was investigated within a range of model freshwater sa... Read More about Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system.

Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS) (2017)
Journal Article
May, J., Robinson, G., Thorn, R., & Reynolds, D. (2017). Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS). Mutagenesis, 32(6), 622-623. https://doi.org/10.1093/mutage/gex033

Electrochemically activated solutions (ECAS) are of interest as potential disinfectants due to high biocidal activity against many microorganisms. They are widely used clinically in some countries (decontamination of surgical instruments and wounds),... Read More about Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS).

Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes (2017)
Journal Article
Clayton, G., Thorn, R., & Reynolds, D. M. (2019). Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes. Journal of Water Process Engineering, 30, Article 100480. https://doi.org/10.1016/j.jwpe.2017.08.018

© 2017 Elsevier Ltd Approximately 800 million people live without clean drinking water. Diarrhoea is responsible for between 1.7 and 2 million deaths each year (primarily children) which are the result of poor drinking water quality and sanitation. T... Read More about Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes.

The in situ bacterial production of fluorescent organic matter; An investigation at a species level (2017)
Journal Article
Fox, B. G., Thorn, R. M. S., Anesio, A. M., & Reynolds, D. M. (2017). The in situ bacterial production of fluorescent organic matter; An investigation at a species level. Water Research, 125, 350-359. https://doi.org/10.1016/j.watres.2017.08.040

© 2017 The Authors Aquatic dissolved organic matter (DOM) plays an essential role in biogeochemical cycling and transport of organic matter throughout the hydrological continuum. To characterise microbially-derived organic matter (OM) from common env... Read More about The in situ bacterial production of fluorescent organic matter; An investigation at a species level.

Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions (2017)
Journal Article
Thorn, R., Pendred, J., & Reynolds, D. M. (2017). Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions. Food Microbiology, 68, 41-50. https://doi.org/10.1016/j.fm.2017.06.018

© 2017 The main aim of this study was to assess the antimicrobial efficacy of electrochemically activated fog (ECAF) for reducing the microbial bio-burden on artificially inoculated fresh produce held under cooled (cucumber and vine tomatoes) or cold... Read More about Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions.

In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry (2017)
Journal Article
Slade, E. A., Thorn, R. M., Lovering, A. M., Young, A., & Reynolds, D. M. (2017). In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry. Journal of Applied Microbiology, 123(1), 233-245. https://doi.org/10.1111/jam.13473

© 2017 The Society for Applied Microbiology Aims: To determine if bacterial species responsible for clinically relevant wound infection produce specific volatile profiles that would allow their speciation. Methods and Results: Selected ion flow tube-... Read More about In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry.

Low light optical detection of whole-cell bioluminescent bacterial bioreporters for visualisation of surface decontamination using nonthermal plasma (2013)
Presentation / Conference
Robinson, G. M., Thorn, R., Hancock, C., & Reynolds, D. M. (2013, May). Low light optical detection of whole-cell bioluminescent bacterial bioreporters for visualisation of surface decontamination using nonthermal plasma. Paper presented at 3rd International Conference on Bio-Sensing Technology, Sitges, Spain

Introduction: Maintenance of a clean, uncontaminated healthcare environment is instrumental in the delivery of modern healthcare. Nonthermal plasma is a technology with potential applications for sterilisation and disinfection in biological and medi... Read More about Low light optical detection of whole-cell bioluminescent bacterial bioreporters for visualisation of surface decontamination using nonthermal plasma.

Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay (2013)
Journal Article
Reynolds, D. M., Thorn, R. M., Thorn, R., Reynolds, D. M., & Robinson, G. M. (2013). Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay. Antimicrobial Agents and Chemotherapy, 57(5), 2216-2225. https://doi.org/10.1128/AAC.02589-12

The main aim of this study was to develop a standardized experimental assay to enable differential antimicrobial comparisons of test biocidal aerosols. This study represents the first chlorine-matched comparative assessment of the antimicrobial activ... Read More about Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay.

The effect of long-term storage on the physiochemical and bactericidal properties of electrochemically activated solutions (2013)
Journal Article
Robinson, G., Thorn, R., & Reynolds, D. (2013). The effect of long-term storage on the physiochemical and bactericidal properties of electrochemically activated solutions. International Journal of Molecular Sciences, 14(1), 457-469. https://doi.org/10.3390/ijms14010457

Electrochemically activated solutions (ECAS) are generated by electrolysis of NaCl solutions, and demonstrate broad spectrum antimicrobial activity and high environmental compatibility. The biocidal efficacy of ECAS at the point of production is wide... Read More about The effect of long-term storage on the physiochemical and bactericidal properties of electrochemically activated solutions.

Microbial volatile compounds in health and disease conditions (2012)
Journal Article
Thorn, R., & Greenman, J. (2012). Microbial volatile compounds in health and disease conditions. Journal of Breath Research, 6(2), 024001. https://doi.org/10.1088/1752-7155/6/2/024001

Microbial cultures and/or microbial associated diseases often have a characteristic smell. Volatile organic compounds (VOCs) are produced by all microorganisms as part of their normal metabolism. The types and classes of VOC produced is wide, includi... Read More about Microbial volatile compounds in health and disease conditions.

Electrochemically activated solutions: Evidence for antimicrobial efficacy and applications in healthcare environments (2012)
Journal Article
Lee, S. W., Thorn, R., Robinson, G., Greenman, J., & Reynolds, D. M. (2012). Electrochemically activated solutions: Evidence for antimicrobial efficacy and applications in healthcare environments. European Journal of Clinical Microbiology and Infectious Diseases, 31(5), 641-653. https://doi.org/10.1007/s10096-011-1369-9

Due to the limitations associated with the use of existing biocidal agents, there is a need to explore new methods of disinfection to help maintain effective bioburden control, especially within the healthcare environment. The transformation of low m... Read More about Electrochemically activated solutions: Evidence for antimicrobial efficacy and applications in healthcare environments.

Application of bacterial bioluminescence to assess the efficacy of fast-acting biocides (2011)
Journal Article
Robinson, G., Tonks, K. M., Thorn, R., & Reynolds, D. M. (2011). Application of bacterial bioluminescence to assess the efficacy of fast-acting biocides. Antimicrobial Agents and Chemotherapy, 55(11), 5214-5219. https://doi.org/10.1128/AAC.00489-11

Traditional microbiological techniques are used to provide reliable data on the rate and extent of kill for a range of biocides. However, such techniques provide very limited data regarding the initial rate of kill of fast-acting biocides over very s... Read More about Application of bacterial bioluminescence to assess the efficacy of fast-acting biocides.

Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro (2011)
Journal Article
Thorn, R., Reynolds, D. M., & Greenman, J. (2011). Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro. Journal of Microbiological Methods, 84(2), 258-264. https://doi.org/10.1016/j.mimet.2010.12.001

Volatile compounds (VCs) are produced by all microorganisms as part of their normal metabolism. The aim of this study was to determine whether bacterial VC profiles could be used to discriminate between selected bacterial species and strains in vitro... Read More about Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro.

Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro (2011)
Journal Article
Thorn, R., Reynolds, D. M., & Greenman, J. (2011). Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro. Journal of Microbiological Methods, 84(2), 258-264. https://doi.org/10.1016/j.mimet.2010.12.001

Volatile compounds (VCs) are produced by all microorganisms as part of their normal metabolism. The aim of this study was to determine whether bacterial VC profiles could be used to discriminate between selected bacterial species and strains in vitro... Read More about Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro.

A novel in vitro flat-bed perfusion biofilm model for determining the potential antimicrobial efficacy of topical wound treatments (2009)
Journal Article
Thorn, R., & Greenman, J. (2009). A novel in vitro flat-bed perfusion biofilm model for determining the potential antimicrobial efficacy of topical wound treatments. Journal of Applied Microbiology, 107(6), 2070-2079. https://doi.org/10.1111/j.1365-2672.2009.04398.x

Aims: To develop an in vitro flat-bed perfusion biofilm model that could be used to determine the antimicrobial efficacy of topically applied treatments. Methods and Results: Pseudomonas aeruginosa and Staphylococcus aureus biofilms were grown within... Read More about A novel in vitro flat-bed perfusion biofilm model for determining the potential antimicrobial efficacy of topical wound treatments.

A novel in vitro flat-bed perfusion biofilm model for determining the potential antimicrobial efficacy of topical wound treatments (2009)
Journal Article
Thorn, R., & Greenman, J. (2009). A novel in vitro flat-bed perfusion biofilm model for determining the potential antimicrobial efficacy of topical wound treatments. Journal of Applied Microbiology, 107(6), 2070-2079. https://doi.org/10.1111/j.1365-2672.2009.04398.x

To develop an in vitro flat-bed perfusion biofilm model that could be used to determine the antimicrobial efficacy of topically applied treatments. METHODS AND RESULTS: Pseudomonas aeruginosa and Staphylococcus aureus biofilms were grown within co... Read More about A novel in vitro flat-bed perfusion biofilm model for determining the potential antimicrobial efficacy of topical wound treatments.

Use of a bioluminescent Pseudomonas aeruginosa strain within an in vitro microbiological system, as a model of wound infection, to assess the antimicrobial efficacy of wound dressings by monitoring light production (2007)
Journal Article
Thorn, R., Nelson, S., & Greenman, J. (2007). Use of a bioluminescent Pseudomonas aeruginosa strain within an in vitro microbiological system, as a model of wound infection, to assess the antimicrobial efficacy of wound dressings by monitoring light production. Antimicrobial Agents and Chemotherapy, 51(9), 3217-3224. https://doi.org/10.1128/AAC.00302-07

A bioluminescent Pseudomonas aeruginosa was incorporated into an in vitro static diffusion method to determine whether light output could be used as a measure of wound dressing efficacy. A significant linear correlation was observed between viable co... Read More about Use of a bioluminescent Pseudomonas aeruginosa strain within an in vitro microbiological system, as a model of wound infection, to assess the antimicrobial efficacy of wound dressings by monitoring light production.

In vitro method to assess the antimicrobial activity and potential efficacy of novel types of wound dressings (2005)
Journal Article
Thorn, R., Greenman, J., & Austin, A. J. (2005). In vitro method to assess the antimicrobial activity and potential efficacy of novel types of wound dressings. Journal of Applied Microbiology, 99(4), 895-901. https://doi.org/10.1111/j.1365-2672.2005.02671.x

Aims: To develop a simple, reproducible in vitro static diffusion method using cellulose disks and defined species to test antimicrobial efficacy of wound dressings. Methods and Results: Cellulose disks were inoculated by immersion in cell suspension... Read More about In vitro method to assess the antimicrobial activity and potential efficacy of novel types of wound dressings.