All Outputs (127)

The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium (2013)
Journal Article

The multinational SYSCILIA consortium aims to gain a mechanistic understanding of the cilium. We utilize multiple parallel high-throughput (HTP) initiatives to develop predictive models of relationships between complex genotypes and variable phenotyp... Read More about The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium.

ZAP-70 Phosphorylation and other prognostic factors in adult B-chronic lymphocytic leukaemia patients (2013)
Thesis

Abstract
B chronic lymphocytic leukaemia (B-CLL) is a disease with an enormously heterogeneous prognosis. Due to lack of effective treatments and the heterogeneity in its course, B-CLL has remained largely incurable. In the last two decades a number... Read More about ZAP-70 Phosphorylation and other prognostic factors in adult B-chronic lymphocytic leukaemia patients.

Direct measurement of ammonia in simulated human breath using an inkjet-printed polyaniline nanoparticle sensor (2013)
Journal Article

A sensor fabricated from the inkjet-printed deposition of polyaniline nanoparticles onto a screen-printed silver interdigitated electrode was developed for the detection of ammonia in simulated human breath samples. Impedance analysis showed that exp... Read More about Direct measurement of ammonia in simulated human breath using an inkjet-printed polyaniline nanoparticle sensor.

Application of a printed silver-based electrocatalyst for H2O2 reduction to the determination of cholesterol (2013)
Presentation / Conference Contribution

Many current clinical disorders such as hypertension, arteriosclerosis, coronary artery disease and cerebral thrombosis are associated with abnormal levels of cholesterol in blood. Therefore, the development of a reliable and simple method for choles... Read More about Application of a printed silver-based electrocatalyst for H2O2 reduction to the determination of cholesterol.

Investigation of the patterning of lyotropic mixtures onto silver paste electrodes via ink jet printing and its effect on the electroreduction of hydrogen peroxide (2013)
Presentation / Conference Contribution

Nanoparticle composites of tungsten oxide and polyaniline for acetone gas sensing at room temperature (2013)
Presentation / Conference Contribution

The development of electrochemical sensors for blood ammonia (2013)
Presentation / Conference Contribution

Taking a breath for better health (2013)
Journal Article

What does your breath say about you? It might tell the world (or at least anyone at close quarters) that you didn’t brush your teeth this morning, or that you ate garlic last night. But there might also be other, subtle and important clues in there a... Read More about Taking a breath for better health.

Temperature response of denitrification rate and greenhouse gas production in agricultural river marginal wetland soils (2013)
Journal Article

Soils are predicted to exhibit significant feedback to global warming via the temperature response of greenhouse gas (GHG) production. However, the temperature response of hydromorphic wetland soils is complicated by confounding factors such as oxyge... Read More about Temperature response of denitrification rate and greenhouse gas production in agricultural river marginal wetland soils.

Development of a printed HDL-cholesterol biosensor based on a novel electrocatalyst for hydrogen peroxide reduction (2013)
Journal Article

Volatile organic compounds (VOCs) found in urine and stool (2013)
Book Chapter

LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: Implications for targeting adenoma stem cells with nsaids (2013)
Journal Article

Cyclooxygenase-2 is overexpressed in the majority of colorectal tumours leading to elevated levels of prostaglandin E2 (PGE2), promoting many hallmarks of cancer. Importantly, PGE2 is reported to enhance Wnt/β-catenin signalling in colorectal carcino... Read More about LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: Implications for targeting adenoma stem cells with nsaids.

Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay (2013)
Journal Article

The main aim of this study was to develop a standardized experimental assay to enable differential antimicrobial comparisons of test biocidal aerosols. This study represents the first chlorine-matched comparative assessment of the antimicrobial activ... Read More about Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay.

The dual role of paramagnetic particles for integrated lysis and measurement in a rapid immunoassay for intracellular proteins (2013)
Journal Article

A novel, integrated lysis and immunoassay methodology and system for intracellular protein measurement are described. The method uses paramagnetic particles both as a lysis agent and assay label resulting in a rapid test requiring minimal operator in... Read More about The dual role of paramagnetic particles for integrated lysis and measurement in a rapid immunoassay for intracellular proteins.

Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome (2013)
Journal Article

Meckel-Gruber syndrome (MKS) is an embryonic lethal ciliopathy resulting from mutations in genes encoding proteins localising to the primary cilium. Mutations in the basal body protein MKS1 account for 7% of cases of MKS. The condition affects the de... Read More about Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome.

Monitoring the effects of fibrinogen concentration on blood coagulation using quartz crystal microbalance (QCM) and its comparison with thromboelastography (2013)
Presentation / Conference Contribution

A novel microfluidic anti-factor Xa assay device for monitoring anticoagulant therapy at the point-of-care. SPIE Microtechnologies (2013)
Presentation / Conference Contribution

Bristol inventor develops self-heating gloves (2013)
Digital Artefact

CoreGenes3.5: A webserver for the determination of core genes from sets of viral and small bacterial genomes (2013)
Journal Article

Background: CoreGenes3.5 is a webserver that determines sets of core genes from viral and small bacterial genomes as an automated batch process. Previous versions of CoreGenes have been used to classify bacteriophage genomes and mine data from pathog... Read More about CoreGenes3.5: A webserver for the determination of core genes from sets of viral and small bacterial genomes.

Microfabricated glucose biosensor for culture welloperation (2013)
Journal Article

A water-based carbon screen-printing ink formulation, containing the redox mediator cobalt phthalocyanine (CoPC) and the enzyme glucose oxidase (GOx), was investigated for its suitability to fabricate glucose microbiosensors in a 96-well microplate f... Read More about Microfabricated glucose biosensor for culture welloperation.