Martijn A. Huynen
The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium
Huynen, Martijn A.; Van Dam, Teunis J.P.; Slaats, Gisela G.; Giles, Rachel H.; van Dam, Teunis JP; Slaats, Gisela G; Huynen, Martijn A; Giles, Rachel H; Wheway, Gabrielle
Authors
Teunis J.P. Van Dam
Gisela G. Slaats
Rachel H. Giles
Teunis JP van Dam
Gisela G Slaats
Martijn A Huynen
Rachel H Giles
Gabrielle Wheway Gabrielle.Wheway@uwe.ac.uk
Occasional Associate Lecturer - CHSS - DAS
Abstract
The multinational SYSCILIA consortium aims to gain a mechanistic understanding of the cilium. We utilize multiple parallel high-throughput (HTP) initiatives to develop predictive models of relationships between complex genotypes and variable phenotypes of ciliopathies. The models generated are only as good as the wet laboratory data fed into them. It is therefore essential to orchestrate a well-annotated and high-confidence dataset to be able to assess the quality of any HTP dataset. Here, we present the inaugural SYSCILIA gold standard of known ciliary components as a public resource. © 2013 van Dam et al.; licensee BioMed Central Ltd.
Citation
Giles, R. H., Slaats, G. G., Van Dam, T. J., Huynen, M. A., van Dam, T. J., Wheway, G., …Giles, R. H. (2013). The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium. Cilia, 2(1), 7. https://doi.org/10.1186/2046-2530-2-7
Journal Article Type | Review |
---|---|
Acceptance Date | May 28, 2013 |
Publication Date | May 31, 2013 |
Deposit Date | Jun 7, 2016 |
Publicly Available Date | Jun 7, 2016 |
Journal | Cilia |
Electronic ISSN | 2046-2530 |
Publisher | BioMed Central |
Peer Reviewed | Peer Reviewed |
Volume | 2 |
Issue | 1 |
Pages | 7 |
DOI | https://doi.org/10.1186/2046-2530-2-7 |
Public URL | https://uwe-repository.worktribe.com/output/940897 |
Publisher URL | http://dx.doi.org/10.1186/2046-2530-2-7 |
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