All Outputs (202)

Test statistics for comparing two proportions with partially overlapping samples (2015)
Journal Article

Standard tests for comparing two sample proportions of a dichotomous dependent variable where there is a combination of paired and unpaired samples are considered. Four new tests are introduced and compared against standard tests and an alternative p... Read More about Test statistics for comparing two proportions with partially overlapping samples.

The psychosocial impact of breast cancer diagnosis and treatment amongst Black, South Asian and White women: Do differences exist between ethnic groups? (2015)
Journal Article

Breast cancer is the most commonly diagnosed cancer in females, affecting women of all ethnic groups. Until now, very little research has captured the psychosocial impact of the disease amongst Black and Minority Ethnic (BME) women, and that which ha... Read More about The psychosocial impact of breast cancer diagnosis and treatment amongst Black, South Asian and White women: Do differences exist between ethnic groups?.

Cardiopulmonary reserve as determined by cardiopulmonary exercise testing correlates with length of stay and predicts complications after radical cystectomy (2015)
Journal Article

© 2014 The Authors. BJU International © 2014 BJU International. ObjectiveTo investigate whether poor preoperative cardiopulmonary reserve and comorbid state dictate high-risk status and can predict complications in patients undergoing radical cystect... Read More about Cardiopulmonary reserve as determined by cardiopulmonary exercise testing correlates with length of stay and predicts complications after radical cystectomy.

The South West Area Mesothelioma and Pemetrexed trial: A multicentre prospective observational study evaluating novel markers of chemotherapy response and prognostication (2015)
Journal Article

© 2015 Cancer Research UK. All rights reserved. Background: Robust markers that predict prognosis and detect early treatment response in malignant pleural mesothelioma (MPM) would enhance patient care. Methods: Consecutive patients with MPM who were... Read More about The South West Area Mesothelioma and Pemetrexed trial: A multicentre prospective observational study evaluating novel markers of chemotherapy response and prognostication.

A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: A proof of principle pilot study (2015)
Journal Article

© 2015 Clive et al. Introduction: Animal studies have shown Zoledronic Acid (ZA) may diminish pleural fluid accumulation and tumour bulk in malignant pleural disease (MPD). We performed a pilot study to evaluate its effects in humans. Methods: We und... Read More about A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: A proof of principle pilot study.

The effect of chemotherapy on health-related quality of life in mesothelioma: Results from the SWAMP trial (2015)
Journal Article

© 2015 Cancer Research UK. All rights reserved. Background: The effect of chemotherapy on health-related quality of life (HRQoL) in malignant pleural mesothelioma (MPM) is poorly understood. Patient-individualised prognostication and prediction of tr... Read More about The effect of chemotherapy on health-related quality of life in mesothelioma: Results from the SWAMP trial.

Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study (2015)
Journal Article

© 2014 Surgical Associates Ltd. Appendicitis is a common clinical diagnosis aided by biochemical, haematological and radiological investigations. The role of some investigations, such as bilirubin, is controversial but could indicate complicated appe... Read More about Predictive value of abnormally raised serum bilirubin in acute appendicitis: A cohort study.

EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers (2015)
Journal Article

Copyright © 2014 The Neurosurgical Foundation. Introduction. EGFR and EGFRvIII analysis is of current interest because of new EGFRvIII vaccine trials opened in the UK. EGFR activation promotes cellular proliferation via activation of MAPK and PI3K-Ak... Read More about EGFR and EGFRvIII analysis in glioblastoma as therapeutic biomarkers.

A pilot randomized controlled trial comparing bismuth iodine paraffin paste external ear pack and no ear pack after middle ear surgery (2015)
Journal Article

© 2013, The Author(s). To pilot a substantive randomized control trial comparing post-operative external ear canal pack with no ear pack after middle ear surgery, 32 adults undergoing primary posterior bony canal wall preserving middle ear surgery we... Read More about A pilot randomized controlled trial comparing bismuth iodine paraffin paste external ear pack and no ear pack after middle ear surgery.

Pleural irrigation trial (PIT): A randomised controlled trial of pleural irrigation with normal saline versus standard care in patients with pleural infection (2015)
Journal Article

© ERS 2015. Pleural infection is increasing in incidence. Despite optimal medical management, up to 30% of patients will die or require surgery. Case reports suggest that irrigation of the pleural space with saline may be beneficial. A randomised con... Read More about Pleural irrigation trial (PIT): A randomised controlled trial of pleural irrigation with normal saline versus standard care in patients with pleural infection.

BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum (2015)
Journal Article

Copyright © 2015 by the American Association of Neuropathologists, Inc. Pilocytic astrocytomas (PAs) are increasingly tested for KIAA1549-BRAF fusions. We used reverse transcription polymerase chain reaction for the 3 most common KIAA1549-BRAF fusion... Read More about BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum.

Women's views and experiences of antenatal enquiry for domestic abuse during pregnancy (2015)
Journal Article

© 2015 John Wiley & Sons Ltd. Objective: The aim of this study was to explore the acceptability of antenatal enquiry for domestic abuse from the perspective of women using maternity services. It also sought to understand the experiences of referral... Read More about Women's views and experiences of antenatal enquiry for domestic abuse during pregnancy.

Multimodal neurophysiological evaluation of primary progressive multiple sclerosis - An increasingly valid biomarker, with limits (2015)
Journal Article

© 2015 Elsevier B.V. Background The promising utility of multi-modality evoked potential batteries to objectively measure multi-tract dysfunction has been evaluated by several groups using different methods. Objective To independently evaluate the us... Read More about Multimodal neurophysiological evaluation of primary progressive multiple sclerosis - An increasingly valid biomarker, with limits.

Interactive ant colony optimization (iACO) for early lifecycle software design (2014)
Journal Article

Finding good designs in the early stages of the software development lifecycle is a demanding multi-objective problem that is crucial to success. Previously, both interactive and non-interactive techniques based on evolutionary algorithms (EAs) have... Read More about Interactive ant colony optimization (iACO) for early lifecycle software design.

Salience and valence of appearance in a population with a visible difference of appearance: Direct and moderated relationships with self-consciousness, anxiety and depression (2014)
Journal Article

Psychometric measures of appearance salience and valence, CARSAL and CARVAL, have been previously demonstrated to be key factors underpinning appearance related self-consciousness and negative affect in the general population. However, the extent to... Read More about Salience and valence of appearance in a population with a visible difference of appearance: Direct and moderated relationships with self-consciousness, anxiety and depression.

The psychosocial impact of living with an ocular prosthesis (2014)
Journal Article

Objective: Many patients are satisfied with their ocular prosthesis, but some describe problems with social interactions, body image and self-esteem. Although both clinical practice and research suggest that the severity of a disfiguring condition do... Read More about The psychosocial impact of living with an ocular prosthesis.

The psychological well-being and appearance concerns of patients presenting with ptosis (2014)
Journal Article

PurposePtosis affects both the function and appearance of the eyes and face, because of drooping of the eyelids. Previous research has focused on functional impairment; however, similar appearance altering eye conditions have been demonstrated to hav... Read More about The psychological well-being and appearance concerns of patients presenting with ptosis.

Do long leg supine CT scanograms correlate with weight-bearing full-length radiographs to measure lower limb coronal alignment? (2014)
Journal Article

Introduction: The gold standard for measuring knee alignment is the lower limb mechanical axis (MA) using weight-bearing lower limb full-length x-ray (FLX). However, CT scanograms (CTS) are becoming increasingly popular in view of lower radiation exp... Read More about Do long leg supine CT scanograms correlate with weight-bearing full-length radiographs to measure lower limb coronal alignment?.

Operative time and outcome of enhanced recovery after surgery after laparoscopic colorectal surgery (2014)
Journal Article

Background and Objectives: Combining laparoscopy and enhanced recovery provides benefit to short-term outcomes after colorectal surgery. Advances in training and techniques have allowed surgeons to operate on cases that are technically challenging an... Read More about Operative time and outcome of enhanced recovery after surgery after laparoscopic colorectal surgery.

The Canadian contribution to the otolaryngology literature: A five year bibliometric analysis (2014)
Journal Article

© 2014 Gurberg et al. Objectives: To assess the 2008-2012 Canadian contribution to the Otolaryngology literature. Methods: All articles published from January 2008 - December 2012 in 5 Otolaryngology journals were reviewed. Nationality, number of aut... Read More about The Canadian contribution to the otolaryngology literature: A five year bibliometric analysis.