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All Outputs (49)

BRIVEST: A ‘real-world’ observational, single-centre study investigating the efficacy, safety and tolerability of Brivaracetam (2022)
Journal Article

Objective: Via measures of efficacy, tolerability, and safety, this open-label, single-center study assessed the overall effectiveness of Brivaracetam (BRV) for the treatment of epilepsy in the context of ‘real-world’ clinical practice. Methods: Unse... Read More about BRIVEST: A ‘real-world’ observational, single-centre study investigating the efficacy, safety and tolerability of Brivaracetam.

Acceptability of Lycra arm sleeve in people with sub-acute stroke: Patients', carers' and clinicians' perspectives (2022)
Journal Article

Background: Previous studies found that the Lycra sleeve has potential to reduce glenohumeral subluxation in people with stroke. The primary aim of this study was to explore the acceptability of the Lycra sleeve from patients’, carers’ and staff perc... Read More about Acceptability of Lycra arm sleeve in people with sub-acute stroke: Patients', carers' and clinicians' perspectives.

A comic-based body image intervention for adolescents in semi-rural Indian schools: Study protocol for a randomized controlled trial (2022)
Journal Article

Adolescents in India experience body dissatisfaction, however, empirically supported interventions are lacking. This paper describes the protocol for the development, acceptability testing, and cluster randomized controlled trial (RCT) of a six-sessi... Read More about A comic-based body image intervention for adolescents in semi-rural Indian schools: Study protocol for a randomized controlled trial.

A phase II trial of cemiplimab alone or in combination with standard of care chemotherapy in locally advanced or metastatic penile carcinoma (EPIC Trial) (2022)
Journal Article

TPS5094 Background: Penile cancer (PC) is rare but its incidence is increasing, with an increase of 21% over the last decade. The rarity of this cancer means a paucity of large prospective clinical trial data to guide the management of locally advanc... Read More about A phase II trial of cemiplimab alone or in combination with standard of care chemotherapy in locally advanced or metastatic penile carcinoma (EPIC Trial).

Safety in numbers: Minimum thresholding, Maximum bounds and Little White Lies : The case of the mean and standard deviation (2022)
Presentation / Conference Contribution

Reporting the sample mean, sample standard deviation and sample size could in some cases lead to the unique identification of the underpinning sample. The likelihood of this reveal via direct enumeration of the possible search space decreases with i... Read More about Safety in numbers: Minimum thresholding, Maximum bounds and Little White Lies : The case of the mean and standard deviation.

Short-Term safety outcomes of mastectomy and immediate prepectoral implant-based breast reconstruction: Pre-BRA prospective multicentre cohort study (2022)
Journal Article

Background: Prepectoral breast reconstruction (PPBR) has recently been introduced to reduce postoperative pain and improve cosmetic outcomes in women having implant-based procedures. High-quality evidence to support the practice of PPBR, however, is... Read More about Short-Term safety outcomes of mastectomy and immediate prepectoral implant-based breast reconstruction: Pre-BRA prospective multicentre cohort study.

Characterising recovery following abdominal aortic aneurysm repair using cardiopulmonary exercise testing and patient reported outcome measures (2022)
Journal Article

Purpose: Surgery is associated with a post-operative stress response, changes in cardiopulmonary reserve, and metabolic demand. Here recovery after abdominal aortic aneurysm repair is investigated using cardiopulmonary exercise testing and patient-re... Read More about Characterising recovery following abdominal aortic aneurysm repair using cardiopulmonary exercise testing and patient reported outcome measures.

Epidemiology and outcomes of tibial plateau fractures in adults aged 60 and over treated in the United Kingdom (2022)
Journal Article

Background: Tibial plateau fractures are common in older adults, often resulting from low-energy falls. Although lower limb fragility fracture care has evolved, the management of tibial plateau fractures in older patients remains poorly researched. T... Read More about Epidemiology and outcomes of tibial plateau fractures in adults aged 60 and over treated in the United Kingdom.

Frequency-dependent characteristics of nerve-mediated ATP and acetylcholine release from detrusor smooth muscle (2022)
Journal Article

New Findings: What is the central question of this study? Is the frequency dependence of co-transmitter release from postganglionic nerve fibres different for each transmitter? What is the main finding and its importance? Release of co-transmitters f... Read More about Frequency-dependent characteristics of nerve-mediated ATP and acetylcholine release from detrusor smooth muscle.

A novel, scalable social media-based intervention Warna-Warni Waktu to reduce body dissatisfaction among young Indonesian women: Protocol for a parallel randomized controlled trial (2022)
Journal Article

Background: Despite the prevalence of body dissatisfaction among young Indonesian women and its consequential negative impacts, there are currently no evidence-based, culturally appropriate interventions to tackle this issue. Therefore, there is a ne... Read More about A novel, scalable social media-based intervention Warna-Warni Waktu to reduce body dissatisfaction among young Indonesian women: Protocol for a parallel randomized controlled trial.

An acceptance and commitment therapy prototype mobile program for individuals with a visible difference: Mixed methods feasibility study (2022)
Journal Article

Background: Mobile apps may offer a valuable platform for delivering evidence-based psychological interventions for individuals with atypical appearances, or visible differences, who experience psychosocial appearance concerns such as appearance-base... Read More about An acceptance and commitment therapy prototype mobile program for individuals with a visible difference: Mixed methods feasibility study.

‘Dove Confident Me Indonesia: Single Session’: Study protocol for a randomised controlled trial to evaluate a school-based body image intervention among Indonesian adolescents (2021)
Journal Article

Background: Due to the prevalence and associated adverse health consequences of negative body image among adolescents globally, there is a need to develop acceptable, effective, and scalable interventions. School-based body image interventions delive... Read More about ‘Dove Confident Me Indonesia: Single Session’: Study protocol for a randomised controlled trial to evaluate a school-based body image intervention among Indonesian adolescents.

A multi-centred sequential trial comparing PEGASUS, an intervention to promote shared decision making about breast reconstruction with usual care (2021)
Journal Article

Decision making about breast reconstruction (BR) is complex. The Patients’ Expectations and Goals: Assisting Shared Understanding of Surgery (PEGASUS) intervention aims to support shared decision making by helping women and clinicians clarify and dis... Read More about A multi-centred sequential trial comparing PEGASUS, an intervention to promote shared decision making about breast reconstruction with usual care.