What are the participants’ perspectives of taking melatonin for the treatment of nocturia in Multiple Sclerosis? -a qualitative study embedded within a double blind RCT

Khan, R; Uren, A; Canham, L; Cottrell, D; Drake, MJ; Cotterill, N

doi:10.1155/2018/4721505

Assessment and treatment of nocturia in endocrine disease in a primary care setting; systematic review and nominal group technique consensus (2022)
Journal Article
Dawson, S., Duncan, L., Ahmed, A., Gimson, A., Henderson, E. J., Rees, J., …Andrews, R. (2022). Assessment and treatment of nocturia in endocrine disease in a primary care setting; systematic review and nominal group technique consensus. European Urology Focus, 8(1), 52-59. https://doi.org/10.1016/j.euf.2021.12.008

Context: Salt and water homeostasis is regulated hormonally, so polyuria can result from endocrine disease directly or via secondary effects. These mechanisms are not consistently considered in primary care management of nocturia. Objective: To condu... Read More about Assessment and treatment of nocturia in endocrine disease in a primary care setting; systematic review and nominal group technique consensus.

Use of the International Consultation on Incontinence Questionnaires bladder diary (ICIQ-BD) in men seeking therapy for lower urinary tract symptoms (LUTS) (2022)
Journal Article
Ito, H., Abrams, P., Lewis, A., Young, G., Blair, P., Cotterill, N., …Drake, M. (2022). Use of the International Consultation on Incontinence Questionnaires bladder diary (ICIQ-BD) in men seeking therapy for lower urinary tract symptoms (LUTS). European Urology Focus, 8(1), 66-74. https://doi.org/10.1016/j.euf.2021.12.009

Background: Completion rates and correspondence to other measures need to be established for the International Consultation on Incontinence Questionnaire (ICIQ) bladder diary (ICIQ-BD) in the assessment of male lower urinary tract symptoms (LUTS). Ob... Read More about Use of the International Consultation on Incontinence Questionnaires bladder diary (ICIQ-BD) in men seeking therapy for lower urinary tract symptoms (LUTS).

Implications of cardiovascular disease for assessment and treatment of nocturia in primary care; systematic review and nominal group technique consensus (2022)
Journal Article
Reyes, P. B. G., Butcher, K., Cotterill, N., Drake, M. J., Gimson, A., Gogola, L., …Dawson, S. (2022). Implications of cardiovascular disease for assessment and treatment of nocturia in primary care; systematic review and nominal group technique consensus. European Urology Focus, 8(1), 26-32. https://doi.org/10.1016/j.euf.2021.12.014

Context: Heart conditions affect salt and water homeostasis as a consequence of the underlying condition, compensatory processes, and therapy, and can result in nocturnal polyuria. These processes need to be identified as part of a full evaluation of... Read More about Implications of cardiovascular disease for assessment and treatment of nocturia in primary care; systematic review and nominal group technique consensus.

Association of sleep disorders with nocturia: A systematic review and nominal group technique consensus on primary care assessment and treatment (2022)
Journal Article
Papworth, E., Dawson, S., Henderson, E. J., Eriksson, S. H., Selsick, H., Rees, J., …Drake, M. J. (2022). Association of sleep disorders with nocturia: A systematic review and nominal group technique consensus on primary care assessment and treatment. European Urology Focus, 8(1), 42-51. https://doi.org/10.1016/j.euf.2021.12.011

Context: Sleep disorders affect responsiveness to sensory information and can cause nocturnal polyuria and reduced sleep depth; hence, these are potentially influential in understanding the mechanism of nocturia. Objective: To report the systematic r... Read More about Association of sleep disorders with nocturia: A systematic review and nominal group technique consensus on primary care assessment and treatment.

Nocturia and chronic kidney disease: Systematic review and nominal group technique consensus for primary care assessment and treatment (2022)
Journal Article
Ridgway, A., Cotterill, N., Dawson, S., Drake, M. J., Henderson, E. J., Huntley, A. L., …Udayaraj, U. (2022). Nocturia and chronic kidney disease: Systematic review and nominal group technique consensus for primary care assessment and treatment. European Urology Focus, 8(1), 18-25. https://doi.org/10.1016/j.euf.2021.12.010

Context: Reduced renal function impairs salt and water homeostasis, which can drive nocturnal or 24-h polyuria. Nocturia can arise early in chronic kidney disease (CKD). Evidence-based recommendations can facilitate management outside nephrology clin... Read More about Nocturia and chronic kidney disease: Systematic review and nominal group technique consensus for primary care assessment and treatment.

Qualitative assessment of the conservative management of nocturia with standardised written materials for Lower Urinary Tract Symptoms in men treated in primary care (2022)
Journal Article
Olaniyi, P., Cotterill, N., Drake, M. J., Frost, J., Lane, J. A., Ridd, M., …Wheeler, J. (2022). Qualitative assessment of the conservative management of nocturia with standardised written materials for Lower Urinary Tract Symptoms in men treated in primary care. European Urology Focus, 8(1), 75-80. https://doi.org/10.1016/j.euf.2022.01.003

Background: Many men prefer conservative treatment of lower urinary tract symptoms (LUTS) but education and self-help guidance are limited in primary care. Objective: To report qualitative interview findings for men reporting nocturia in a primary ca... Read More about Qualitative assessment of the conservative management of nocturia with standardised written materials for Lower Urinary Tract Symptoms in men treated in primary care.

Female urgency, trial of urodynamics as routine evaluation (FUTURE study): A superiority randomised clinical trial to evaluate the effectiveness and cost-effectiveness of invasive urodynamic investigations in management of women with refractory overactive bladder symptoms (2021)
Journal Article
Abdel-fattah, M., Chapple, C., Guerrero, K., Dixon, S., Cotterill, N., Ward, K., …Norrie, J. (2021). Female urgency, trial of urodynamics as routine evaluation (FUTURE study): A superiority randomised clinical trial to evaluate the effectiveness and cost-effectiveness of invasive urodynamic investigations in management of women with refractory overactive bladder symptoms. Trials, 22(1), Article 745. https://doi.org/10.1186/s13063-021-05661-3

Background: Overactive bladder (OAB) syndrome is a symptom complex affecting 12–14% of the UK adult female population. Symptoms include urinary urgency, with or without urgency incontinence, increased daytime urinary frequency and nocturia. OAB has a... Read More about Female urgency, trial of urodynamics as routine evaluation (FUTURE study): A superiority randomised clinical trial to evaluate the effectiveness and cost-effectiveness of invasive urodynamic investigations in management of women with refractory overactive bladder symptoms.

The development of the Cystectomy-Pathway Assessment Tool (C-PAT): a concise tool to assess the quality of care in the cystectomy pathway (2021)
Journal Article
Uren, A., Cotterill, N., Abrams, P., Catto, J., Patel, B., McGrath, J., …Rowe, E. (2022). The development of the Cystectomy-Pathway Assessment Tool (C-PAT): a concise tool to assess the quality of care in the cystectomy pathway. BJU International, 129(6), 708-717. https://doi.org/10.1111/bju.15539

Objectives: To develop and test the psychometric properties of a concise, patient-reported questionnaire, designed to assess key aspects of the radical cystectomy (RC) patient pathway that are important to both patients and clinicians. Patients and M... Read More about The development of the Cystectomy-Pathway Assessment Tool (C-PAT): a concise tool to assess the quality of care in the cystectomy pathway.

‘We tend to get pad happy’: A qualitative study of health practitioners’ perspectives on the quality of continence care for older people in hospital (2021)
Journal Article
Percival, J., Abbott, K., Allain, T., Bradley, R., Cramp, F., Donovan, J. L., …Cotterill, N. (2021). ‘We tend to get pad happy’: A qualitative study of health practitioners’ perspectives on the quality of continence care for older people in hospital. BMJ Open Quality, 10(2), Article e001380. https://doi.org/10.1136/bmjoq-2021-001380

Bladder and bowel control difficulties affect 20% and 10% of the UK population, respectively, touch all age groups and are particularly prevalent in the older (65+ years) population. However, the quality of continence care is often poor, compromising... Read More about ‘We tend to get pad happy’: A qualitative study of health practitioners’ perspectives on the quality of continence care for older people in hospital.

Seizing the opportunity to improve patient care: Pelvic Floor services in 2021 and beyond (2021)
Report
Cotterill, N. (2021). Seizing the opportunity to improve patient care: Pelvic Floor services in 2021 and beyond. https://www.pelvicfloorreport.com/: The Pelvic Floor Society

Outcomes of a noninferiority randomised controlled trial of surgery for men with urodynamic stress incontinence after prostate surgery (MASTER) (2021)
Journal Article
Abrams, P., Constable, L. D., Cooper, D., MacLennan, G., Drake, M. J., Harding, C., …Glazener, C. (2021). Outcomes of a noninferiority randomised controlled trial of surgery for men with urodynamic stress incontinence after prostate surgery (MASTER). European Urology, 79(6), 812-823. https://doi.org/10.1016/j.eururo.2021.01.024

Background Stress urinary incontinence (SUI) is common after radical prostatectomy and likely to persist despite conservative treatment. The sling is an emerging operation for persistent SUI, but randomised controlled trial (RCT) comparison with the... Read More about Outcomes of a noninferiority randomised controlled trial of surgery for men with urodynamic stress incontinence after prostate surgery (MASTER).

Thulium laser transurethral vaporesection of the prostate versus transurethral resection of the prostate for men with lower urinary tract symptoms or urinary retention (UNBLOCS): A randomised controlled trial (2020)
Journal Article
Hashim, H., Worthington, J., Abrams, P., Young, G., Taylor, H., Noble, S. M., …Lane, J. A. (2020). Thulium laser transurethral vaporesection of the prostate versus transurethral resection of the prostate for men with lower urinary tract symptoms or urinary retention (UNBLOCS): A randomised controlled trial. Lancet, 396(10243), 50-61. https://doi.org/10.1016/S0140-6736%2820%2930537-7

Background: Transurethral resection of the prostate (TURP) is the standard operation for benign prostatic obstruction. Thulium laser transurethral vaporesection of the prostate (ThuVARP) is a technique with suggested advantages over TURP, including r... Read More about Thulium laser transurethral vaporesection of the prostate versus transurethral resection of the prostate for men with lower urinary tract symptoms or urinary retention (UNBLOCS): A randomised controlled trial.

The International Consultation on Incontinence Questionnaires (ICIQ): An update on status and direction (2020)
Journal Article
Uren, A. D., Uren, A., Cotterill, N., Pardoe, M., & Abrams, P. (2020). The International Consultation on Incontinence Questionnaires (ICIQ): An update on status and direction. Neurourology and Urodynamics, 39(6), 1889-1896. https://doi.org/10.1002/nau.24437

Aims: In its 22nd year, the International Consultation on Incontinence Questionnaire (ICIQ) project continues to promote its primary objective; the development and dissemination of patient completed questionnaires for the standardized, high-quality a... Read More about The International Consultation on Incontinence Questionnaires (ICIQ): An update on status and direction.

Grading severity and bother using the International Prostate Symptom Score and International Consultation on Incontinence Questionnaire Male Lower Urinary Tract Symptoms Score in men seeking lower urinary tract symptoms therapy (2020)
Journal Article
Ito, H., Young, G. J., Lewis, A. L., Blair, P. S., Cotterill, N., Lane, J. A., …Abrams, P. (2020). Grading severity and bother using the International Prostate Symptom Score and International Consultation on Incontinence Questionnaire Male Lower Urinary Tract Symptoms Score in men seeking lower urinary tract symptoms therapy. Journal of Urology, The, 204(5), 1003-1011. https://doi.org/10.1097/JU.0000000000001149

PURPOSE: We established severity banding ranges, bother assessment and key item content in principal patient reported outcomes measures in men seeking therapy for lower urinary tract symptoms. MATERIALS AND METHODS: Data for International Prostate Sy... Read More about Grading severity and bother using the International Prostate Symptom Score and International Consultation on Incontinence Questionnaire Male Lower Urinary Tract Symptoms Score in men seeking lower urinary tract symptoms therapy.

International Consultation on Incontinence Questionnaire-Satisfaction: psychometric testing of a new patient-reported outcome measure for the evaluation of satisfaction after urological surgery (2020)
Journal Article
Uren, A. D., Cotterill, N., Hashim, H., Worthington, J., Kapoor, D., & Abrams, P. (2020). International Consultation on Incontinence Questionnaire-Satisfaction: psychometric testing of a new patient-reported outcome measure for the evaluation of satisfaction after urological surgery. BJU International, 126(2), 286-291. https://doi.org/10.1111/bju.15091

Objectives: To evaluate the psychometric properties of a new patient-reported outcome measure (PROM), the International Consultation on Incontinence Questionnaire-Satisfaction (ICIQ-S), to assess satisfaction after urological surgery. Subjects/Patien... Read More about International Consultation on Incontinence Questionnaire-Satisfaction: psychometric testing of a new patient-reported outcome measure for the evaluation of satisfaction after urological surgery.

TReatIng Urinary symptoms in Men in Primary Healthcare using non-pharmacological and non-surgical interventions (TRIUMPH) compared with usual care: Study protocol for a cluster randomised controlled trial (2019)
Journal Article
Frost, J., Lane, J. A., Cotterill, N., Fader, M., Hackshaw-McGeagh, L., Hashim, H., …Worthington, J. (2019). TReatIng Urinary symptoms in Men in Primary Healthcare using non-pharmacological and non-surgical interventions (TRIUMPH) compared with usual care: Study protocol for a cluster randomised controlled trial. Trials, 20, Article 546. https://doi.org/10.1186/s13063-019-3648-1

Background: Lower urinary tract symptoms (LUTS) can relate to urinary storage or voiding. In men, the prevalence and severity of LUTS increases with age, with a significant impact on quality of life. The majority of men presenting with LUTS are manag... Read More about TReatIng Urinary symptoms in Men in Primary Healthcare using non-pharmacological and non-surgical interventions (TRIUMPH) compared with usual care: Study protocol for a cluster randomised controlled trial.

Thulium laser transurethral vaporesection of the prostate versus transurethral resection of the prostate: The UNBLOCS RCT and economic evaluation (2019)
Report
Worthington, J., Lane, J., Taylor, H., Young, G., Noble, S., Abrams, P., …Hashim, H. (in press). Thulium laser transurethral vaporesection of the prostate versus transurethral resection of the prostate: The UNBLOCS RCT and economic evaluation

Background: Transurethral resection of the prostate (TURP) is the standard operation for benign prostatic obstruction (BPO). Thulium laser transurethral vaporesection of the prostate (ThuVARP) vaporises and resects the prostate using a technique simi... Read More about Thulium laser transurethral vaporesection of the prostate versus transurethral resection of the prostate: The UNBLOCS RCT and economic evaluation.

The development of the ICIQ-UAB: A patient reported outcome measure for underactive bladder (2019)
Journal Article
Uren, A. D., Cotterill, N., Harding, C., Hillary, C., Chapple, C., Lasch, K., …Abrams, P. (2019). The development of the ICIQ-UAB: A patient reported outcome measure for underactive bladder. Neurourology and Urodynamics, 38(3), 996-1004. https://doi.org/10.1002/nau.23947

Aims: To present the development of the International Consultation on Incontinence Questionnaire-underactive bladder (ICIQ-UAB) as the first patient reported outcome measure for the assessment of the symptoms and impact on the health-related quality... Read More about The development of the ICIQ-UAB: A patient reported outcome measure for underactive bladder.

Conservative interventions for urinary or faecal incontinence, or both, in adults with multiple sclerosis (2018)
Journal Article
Cotterill, N., Sullivan, A., Norton, C., Wilkins, A., Weir, I., Kilonzo, M., & Drake, M. J. (2018). Conservative interventions for urinary or faecal incontinence, or both, in adults with multiple sclerosis. Cochrane Database of Systematic Reviews, 2018(10), https://doi.org/10.1002/14651858.CD013150

© 2018 The Cochrane Collaboration. This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of conservative interventions for urinary or faecal incontinence (or both) in adults with multiple sclero... Read More about Conservative interventions for urinary or faecal incontinence, or both, in adults with multiple sclerosis.

What are the participants’ perspectives of taking melatonin for the treatment of nocturia in Multiple Sclerosis? -a qualitative study embedded within a double blind RCT (2018)
Journal Article
Khan, R., Uren, A., Canham, L., Cottrell, D., Drake, M., & Cotterill, N. (2018). What are the participants’ perspectives of taking melatonin for the treatment of nocturia in Multiple Sclerosis? -a qualitative study embedded within a double blind RCT. Multiple Sclerosis International, 2018, 4721505. https://doi.org/10.1155/2018/4721505

Background: Multiple Sclerosis (MS) is a chronic neurological disorder caused by neurodegeneration within the central nervous system. It results in impaired physical, cognitive and psychological functioning and can also lead to lower urinary tract sy... Read More about What are the participants’ perspectives of taking melatonin for the treatment of nocturia in Multiple Sclerosis? -a qualitative study embedded within a double blind RCT.

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