Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: Multicentre cohort study

Kendrick, Denise; Baker, R.; Hill, T.; Beckett, Kate; Coupland, C.; Kellezi, B.; Joseph, S.; Barnes, J.; Sleney, J.; Christie, N.; Morriss, S

Abstract

© 2018 Elsevier Inc. Objective: To quantify psychological morbidity and identify baseline factors associated with depression, anxiety and post-traumatic distress symptoms up to 12 months post-injury. Methods: Multicentre cohort study of 668 adults, aged 16 to 70, admitted to 4 UK NHS hospital trusts. Data on injury, socio-demographic characteristics and health status was collected at recruitment. Depression, anxiety and post-traumatic distress were measured at 1, 2, 4 and 12 months post-injury. Multilevel linear regression assessed associations between patient and injury characteristics and psychological outcomes over 12 months follow-up. Results: Depression, anxiety and post-traumatic distress scores were highest 1 month post-injury, and remained above baseline at 2, 4 and 12 months post-injury. Moderate or severe injuries, previous psychiatric diagnoses, higher pre-injury depression and anxiety scores, middle age (45–64 years), greater deprivation and lower pre-injury quality of life (QoL) were associated with higher depression scores post-injury. Previous psychiatric diagnoses, higher pre-injury depression and anxiety scores, middle age, greater deprivation and lower pre-injury QoL were associated with higher anxiety scores post-injury. Traffic injuries or injuries from being struck by objects, multiple injures (≥3), being female, previous psychiatric diagnoses, higher pre-injury anxiety scores and greater deprivation were associated with higher post-traumatic distress scores post-injury. Conclusion: A range of risk factors, identifiable shortly after injury, are associated with psychological morbidity occurring up to 12 months post-injury in a general trauma population. Further research is required to explore the utility of these, and other risk factors in predicting psychological morbidity on an individual patient basis.

• Journal Article Type: Article
• Acceptance Date: Jun 11, 2018
• Online Publication Date: Jun 12, 2018
• Publication Date: Sep 1, 2018
• Deposit Date: Jul 6, 2018
• Publicly Available Date: Jun 12, 2019
• Journal: Journal of Psychosomatic Research
• Print ISSN: 0022-3999
• Electronic ISSN: 1879-1360
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 112
• Pages: 15-24
• DOI: https://doi.org/10.1016/j.jpsychores.2018.06.008
• Keywords: depression, anxiety, PTSD, injury, trauma
• Public URL: https://uwe-repository.worktribe.com/output/861769
• Publisher URL: https://doi.org/10.1016/j.jpsychores.2018.06.008
• Contract Date: Jul 6, 2018