Single nucleotide polymorphism (SNP) in CYP17A1 (rs743572) gene as a risk of prostate cancer development - a preliminary report in Caucasian group
(2013)
Presentation / Conference Contribution
Olena Doran's Outputs (93)
Effect of breed on fatty acid composition and lipogenic enzyme abundance in the subcutaneous adipose tissue of pigs (2013)
Journal Article
This study investigated the role of lipogenic enzyme expression in breed-specific fat deposition in pigs. Objectives: (i) determine effect of breed on the relative abundance of the key lipogenic enzymes stearoyl-CoA desaturase (SCD), delta-6 desatura... Read More about Effect of breed on fatty acid composition and lipogenic enzyme abundance in the subcutaneous adipose tissue of pigs.
The present study assessed the effect of pig genotype (fatty v. lean) and dietary protein and lysine (Lys) levels (normal v. reduced) on intramuscular fat (IMF) content, subcutaneous adipose tissue (SAT) deposition, fatty acid composition and mRNA le... Read More about Differential effects of reduced protein diets on fatty acid composition and gene expression in muscle and subcutaneous adipose tissue of Alentejana purebred and Large White ×â Landrace ×â Pietrain crossbred pigs.
Trpm8 agonists modulate contraction of the pig urinary bladder (2013)
Journal Article
The transient receptor potential melastin-8 (TRPM8) channel is activated by the "cooling" compounds menthol and icilin. Pathophysiologically, it is implicated in the overactive bladder and bladder cooling reflex, but the activity of TRPM8 in normal b... Read More about Trpm8 agonists modulate contraction of the pig urinary bladder.
Use of whole blood for analysis of disease-associated biomarkers (2013)
Journal Article
Analyses for diagnosis and monitoring of pathological conditions often rely on blood samples, partly due to relative ease of collection. However, many interfering substances largely preclude the use of whole blood itself, necessitating separation of... Read More about Use of whole blood for analysis of disease-associated biomarkers.
Boar taint: Challenges and opportunities (2013)
Presentation / Conference Contribution
Hepatic lipogenic enzyme expression in pigs is affected by selection for decreased backfat thickness at constant intramuscular fat content (2013)
Journal Article
This study investigated (i) whether genetic selection for decreased backfat thickness at constant intramuscular fat (IMF) affects the expression of lipogenic enzymes in pig liver and (ii) whether expression of the hepatic lipogenic enzymes is related... Read More about Hepatic lipogenic enzyme expression in pigs is affected by selection for decreased backfat thickness at constant intramuscular fat content.
Fatty acid composition and lipogenic enzyme protein expression in subcutaneous adipose tissue of male pigs vaccinated against boar taint, barrows, and entire boars (2013)
Journal Article
Objectives of this study were to compare fatty acid composition of subcutaneous adipose tissue of entire boars, barrows, and male pigs vaccinated against boar taint with a vaccine containing a GnRH analogue-protein conjugate (Improvac, Pfizer Animal... Read More about Fatty acid composition and lipogenic enzyme protein expression in subcutaneous adipose tissue of male pigs vaccinated against boar taint, barrows, and entire boars.
Effect of pig breed and dietary protein level on selected fatty acids and stearoylcoenzyme A desaturase protein expression in longissimus muscle and subcutaneous fat (2013)
Journal Article
The aims of the study were 1) to investigate effects of a low protein diet on fatty acids content and composition of the LM and subcutaneous adipose tissue in 3 genetically diverse breeds, Large White × Landrace, Alentejano, and Bizaro, and 2) to det... Read More about Effect of pig breed and dietary protein level on selected fatty acids and stearoylcoenzyme A desaturase protein expression in longissimus muscle and subcutaneous fat.
Investigation of Testosterone, Androstenone, and Estradiol Metabolism in HepG2 Cells and Primary Culture Pig Hepatocytes and Their Effects on 17βHSD7 Gene Expression (2012)
Journal Article
Steroid metabolism is important in various species. The accumulation of androgen metabolite, androstenone, in pig adipose tissue is negatively associated with pork flavor, odour and makes the meat unfit for human consumption. The 17β-hydroxysteroid d... Read More about Investigation of Testosterone, Androstenone, and Estradiol Metabolism in HepG2 Cells and Primary Culture Pig Hepatocytes and Their Effects on 17βHSD7 Gene Expression.
Influence of oilseed supplement ranging in n-6/n-3 ratio on fatty acid composition and δ5-, δ6-desaturase protein expression in steer muscles (2012)
Journal Article
This study investigated effects of roasted or extruded oilseed supplementation ranging in n-6/n-3 ratios from 0.3 to 5.0 on the fatty acid composition and expression of delta-5 desaturase (δ5d) and δ6-desaturase (δ6d) protein in commercial steer chee... Read More about Influence of oilseed supplement ranging in n-6/n-3 ratio on fatty acid composition and δ5-, δ6-desaturase protein expression in steer muscles.
Expression of the hepatic skatole- and androstenone-metabolising enzymes in entire male pigs of two live weights (2012)
Journal Article
The aim of the present study was to investigate an in vivo relationship between increased levels of testicular steroids and protein expression of the key enzymes involved in hepatic metabolism of skatole (cytochrome P4502E1 and CYP2E1 and CYP2A) and... Read More about Expression of the hepatic skatole- and androstenone-metabolising enzymes in entire male pigs of two live weights.
Role of lipogenic enzymes expression in breed-specific fatty acid composition in pigs (2011)
Presentation / Conference Contribution
Relationship between the hepatic SULT2A1 protein expression and backfat androstenone level in pigs of three breeds (2010)
Presentation / Conference Contribution
Excessive accumulation of androstenone in pig adipose tissue contributes to the phenomenon of boar taint, an off-odour of some cooked pork. One of the reasons for high androstenone accumulation is a low rate of androstenone metabolism in pig liver. T... Read More about Relationship between the hepatic SULT2A1 protein expression and backfat androstenone level in pigs of three breeds.
Effect of selection for decreased backfat thickness on expression of delta-6 desaturase and fatty acid synthase in pig liver (2010)
Presentation / Conference Contribution
Effect of dietary fatty acids on expression of lipogenic enzymes and fatty acid profile in tissues of bulls (2010)
Journal Article
This study investigated the effects of dietary linolenic acid (C18:3n-3) v. linoleic acid (C18:2n-6) on fatty acid composition and protein expression of key lipogenic enzymes, acetyl-CoA carboxylase (ACC), stearoyl-CoA desaturase (SCD) and delta 6 de... Read More about Effect of dietary fatty acids on expression of lipogenic enzymes and fatty acid profile in tissues of bulls.
Comparison of two derivatisation methods for conjugated linoleic acid isomer analysis by Ag+-HPLC/DAD in beef fat (2010)
Journal Article
Two different procedures for the methylation of conjugated linoleic acid isomers (CLA) were compared by silver ion (Ag+)-HPLC. The base-catalysed method followed by an acid-catalysed method (NaOCH3/ BF3), and base hydrolysis followed by methylation w... Read More about Comparison of two derivatisation methods for conjugated linoleic acid isomer analysis by Ag+-HPLC/DAD in beef fat.