Jason Mansell's Outputs (3)

Ternary nanocomposite potentiates the lysophosphatidic acid effect on human osteoblast (MG63) maturation (2023)
Journal Article

Aim: This study aimed to investigate the potential of ternary nanocomposite (TNC) to support MG63 osteoblast maturation to EB1089-(3S)1-fluoro-3-hydroxy-4-(oleoyloxy)butyl-1-phosphonate (FHBP) cotreatment. Materials & methods: Binary (P25/reduced gra... Read More about Ternary nanocomposite potentiates the lysophosphatidic acid effect on human osteoblast (MG63) maturation.

An N-cyanoamide derivative of lithocholic acid co-operates with lysophosphatidic acid to promote human osteoblast (MG63) differentiation (2023)
Journal Article

Less-calcaemic vitamin D receptor (VDR) agonists have the potential to promote osteoblast maturation in a bone regenerative setting. The emergence of lithocholic acid (LCA) as a bona fide VDR agonist holds promise as an adjunct for arthroplasty follo... Read More about An N-cyanoamide derivative of lithocholic acid co-operates with lysophosphatidic acid to promote human osteoblast (MG63) differentiation.

Development of an antimicrobial lipid coating to prevent infections in uncemented joint replacements (2023)
Presentation / Conference Contribution

Preventing infections in joint replacements is a major ongoing challenge, with limited effective clinical technologies currently available for uncemented knee and hip prostheses. This research aims to develop a coating for titanium implants, consisti... Read More about Development of an antimicrobial lipid coating to prevent infections in uncemented joint replacements.