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Prof. Tony Killard's Outputs (97)

Effects of four commercially available factor Xa proteins on the fluorogenic anti-factor Xa assay when monitoring unfractionated heparin (2012)
Journal Article

Four commercially available factor Xa (FXa) reagents were evaluated in a fluorogenic anti-FXa assay. The four reagents - of which three were of human origin and the fourth was bovine - were compared in terms of the resulting assay dynamic ranges, lag... Read More about Effects of four commercially available factor Xa proteins on the fluorogenic anti-factor Xa assay when monitoring unfractionated heparin.

Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti-FXa assays (2011)
Journal Article

Novel and sensitive plate-based fluorogenic anti-factor Xa (FXa) assays were investigated to quantify unfractionated heparin (UFH) in human plasma and whole blood within the therapeutic ranges of 0-1.6. U/mL and 0-0.8. U/mL, respectively. Two fluorog... Read More about Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti-FXa assays.

Comparison of a fluorogenic anti-FXa assay with a central laboratory chromogenic anti-FXa assay for measuring LMWH activity in patient plasmas (2011)
Journal Article

Introduction: Low molecular weight heparins (LMWHs) are used worldwide for the treatment and prophylaxis of thromboembolic disorders. Routine laboratory tests are not required due to the predictable pharmacokinetics of LMWHs, with the exception of pr... Read More about Comparison of a fluorogenic anti-FXa assay with a central laboratory chromogenic anti-FXa assay for measuring LMWH activity in patient plasmas.

Comparison of the anticoagulant response of a novel fluorogenic anti-FXa assay with two commercial anti-FXa chromogenic assays (2011)
Journal Article

Introduction: Fast and accurate monitoring is crucial in the successful regulation of coagulation therapy. For the treatment of venous thromboembolism, both unfractionated heparin (UFH) and low molecular weight heparins (LMWHs) are commonly administe... Read More about Comparison of the anticoagulant response of a novel fluorogenic anti-FXa assay with two commercial anti-FXa chromogenic assays.

Printed polyaniline-modified interdigitated electrodes for detection and quantification of ammonia in breath (2011)
Presentation / Conference Contribution

A range of pathological conditions can lead to elevated blood ammonia and urea nitrogen levels. These include kidney and liver dysfunction and urea cycle defects. These conditions result in severe reduction in quality and quantity of life. Blood nitr... Read More about Printed polyaniline-modified interdigitated electrodes for detection and quantification of ammonia in breath.