Outputs (153)

Which elements of hospital-based clinical decision support tools for the assessment and management of children with head injury can be adapted for use by paramedics in prehospital care? A systematic mapping review and narrative synthesis (2024)
Journal Article
Proctor, A., Lyttle, M., Billing, J., Shaw, P., Simpson, J., Voss, S., & Benger, J. R. (2024). Which elements of hospital-based clinical decision support tools for the assessment and management of children with head injury can be adapted for use by paramedics in prehospital care? A systematic mapping review and narrative synthesis. BMJ Open, 14(2), Article e078363. https://doi.org/10.1136/bmjopen-2023-078363

Objective Hospital-based clinical decision tools support clinician decision-making when a child presents to the emergency department with a head injury, particularly regarding CT scanning. However, there is no decision tool to support prehospital cli... Read More about Which elements of hospital-based clinical decision support tools for the assessment and management of children with head injury can be adapted for use by paramedics in prehospital care? A systematic mapping review and narrative synthesis.

The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland (2023)
Journal Article
Williams, T. C., Marlow, R., Hardelid, P., Lyttle, M. D., Lewis, K. M., Mpamhanga, C. D., …Roland, D. (in press). The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland. Journal of Infectious Diseases, https://doi.org/10.1093/infdis/jiad551

Interventions introduced to reduce the spread of SARS-CoV-2 led to a widespread reduction in childhood infections. However, from spring 2021 onwards the United Kingdom and Ireland experienced an unusual out-of-season epidemic of respiratory disease.... Read More about The clinical impact of serious respiratory disease in children under the age of two years during the 2021-2022 bronchiolitis season in England, Scotland and Ireland.

Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study (2023)
Journal Article
Craig, S., Xu, Y., Robas, K., Iramain, R., Yock-Corrales, A., Soto-Martinez, M. E., …Babl, F. E. (2023). Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study. BMJ Open Respiratory Research, 10(1), Article e001723. https://doi.org/10.1136/bmjresp-2023-001723

Objective To identify the outcomes considered important, and factors influencing the patient experience, for parents and caregivers of children presenting to hospital with a severe acute exacerbation of asthma. This work contributes to the outcome-id... Read More about Core outcomes and factors influencing the experience of care for children with severe acute exacerbations of asthma: A qualitative study.

Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol (2023)
Journal Article
Umana, E., Mills, C., Norman-Bruce, H., Wilson, K., Mitchell, H., Mcfetridge, L., …Waterfield, T. (2023). Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol. BMJ Open, 13(9), Article e075823. https://doi.org/10.1136/bmjopen-2023-075823

Introduction Febrile infants 90 days and younger are at risk of invasive bacterial infections (bacteraemia and meningitis) and urinary tract infections. Together this is previously termed serious bacterial infection with an incidence of approximately... Read More about Applying clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland: Febrile Infant Diagnostic Assessment and Outcome (FIDO) Study protocol.

Comparison of injury patterns and interventions between adolescent, adult and paediatric trauma cases: A cross-sectional review of TARN data (2023)
Journal Article
Mullen, S., Tolson, A., Bouamra, O., Watson, B., Lyttle, M. D., Roland, D., & James, D. (2023). Comparison of injury patterns and interventions between adolescent, adult and paediatric trauma cases: A cross-sectional review of TARN data. BMJ Open, 13(5), Article e064101. https://doi.org/10.1136/bmjopen-2022-064101

Objectives The aim is to compare adolescent (10-24.99 years) trauma patterns and interventions to adult (≥25) and paediatric cases (

A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments (2023)
Journal Article
Bird, C., Hayward, G. N., Turner, P. J., Merrick, V., Lyttle, M. D., Mullen, N., & Fanshawe, T. R. (2023). A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments. Journal of the Pediatric Infectious Diseases Society, 12(5), 290-297. https://doi.org/10.1093/jpids/piad024

BACKGROUND: Microscopy is the gold standard for malaria diagnosis but is dependent on trained personnel. Rapid diagnostic tests (RDTs) form the mainstay of diagnosis in endemic areas without access to high-quality microscopy. We aimed to evaluate whe... Read More about A diagnostic accuracy study to evaluate standard rapid diagnostic test (RDT) alone to safely rule out imported malaria in children presenting to UK emergency departments.

Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review (2023)
Journal Article
Ijaz, S., Scott, L., Dawson, S., Wilson, R., Jackson, J., Birnie, K., …Mytton, J. (in press). Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review. Archives of Disease in Childhood, 108(6), 492-497. https://doi.org/10.1136/archdischild-2022-325202

Objective: To identify demographic, premorbid and injury-related factors, or biomarkers associated with long-term (≥3 months) adverse outcomes in children after mild traumatic brain injury (mTBI). Design: Scoping review of literature. Patients: Child... Read More about Factors related to adverse long-term outcomes after mild traumatic brain injury in children: A scoping review.

International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study (2023)
Journal Article
Gray, C. S., Xu, Y., Babl, F. E., Dalziel, S., Powell, C. V., Chong, S., …Craig, S. (2023). International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study. BMJ Open Respiratory Research, 10(1), Article e001502. https://doi.org/10.1136/bmjresp-2022-001502

Background: Acute exacerbations of asthma are common in children, however, treatment decisions for severe exacerbations are challenging due to a lack of robust evidence. In order to create more robust research, a core set of outcome measures needs to... Read More about International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: A qualitative interview study.

Assessment and management of children with head injury: Practice and opinion (2023)
Journal Article
Proctor, A., Voss, S., Lyttle, M., & Benger, J. (2023). Assessment and management of children with head injury: Practice and opinion. Journal of Paramedic Practice, 15(2), 58-64. https://doi.org/10.12968/jpar.2023.15.2.58

Background: Head injury is common in children with approximately 700 000 attendances at emergency departments annually; one-third are conveyed by ambulance. However, 75% of them are discharged with no treatment. Most head-injured children could be ma... Read More about Assessment and management of children with head injury: Practice and opinion.

The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents (2023)
Journal Article
Haag, K., Hiller, R., McGuire, R., Lyttle, M., & Halligan, S. L. (2023). The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents. Journal of Traumatic Stress, 36(1), 218-229. https://doi.org/10.1002/jts.22902

Social support has been linked to posttrauma adjustment in children and adolescents, but the components of good support remain poorly defined. We conducted qualitative interviews with 30 youths aged 7–16 years after being admitted to a hospital follo... Read More about The journey back to normality: Support systems and posttrauma needs following exposure to single-incident trauma among children and adolescents.

A systematic literature review of the relationship between parenting responses and child post-traumatic stress symptoms (2022)
Journal Article
Afzal, N., Ye, S., Page, A. C., Trickey, D., Lyttle, M. D., Hiller, R. M., & Halligan, S. L. (2023). A systematic literature review of the relationship between parenting responses and child post-traumatic stress symptoms. European Journal of Psychotraumatology, 14(1), Article 2156053. https://doi.org/10.1080/20008066.2022.2156053

Background: Parents are a key source of support for children exposed to single-incident/acute traumas and can thereby play a potentially significant role in children’s post-trauma psychological adjustment. However, the evidence base examining parenta... Read More about A systematic literature review of the relationship between parenting responses and child post-traumatic stress symptoms.

International variation in evidence-based emergency department management of bronchiolitis: a retrospective cohort study (2022)
Journal Article
Lirette, M., Kuppermann, N., Finkelstein, Y., Zemek, R., Plint, A. C., Florin, T. A., …Schuh, S. (2022). International variation in evidence-based emergency department management of bronchiolitis: a retrospective cohort study. BMJ Open, 12(12), e059784. https://doi.org/10.1136/bmjopen-2021-059784

OBJECTIVES: We aimed to evaluate the international variation in the use of evidence-based management (EBM) in bronchiolitis. We hypothesised that management consistent with full-EBM practices is associated with the research network of care, adjusted... Read More about International variation in evidence-based emergency department management of bronchiolitis: a retrospective cohort study.

Incidence of traumatic brain injuries in head-injured children with seizures (2022)
Journal Article
Borland, M. L., Dalziel, S. R., Phillips, N., Dalton, S., Lyttle, M. D., Bressan, S., …Babl, F. E. (2023). Incidence of traumatic brain injuries in head-injured children with seizures. Emergency Medicine Australasia, 35(2), 289-296. https://doi.org/10.1111/1742-6723.14112

Objective: Incidence and short-term outcomes of clinically important traumatic brain injury (ciTBI) in head-injured children presenting to ED with post-traumatic seizure (PTS) is not described in current literature. Methods: Planned secondary analysi... Read More about Incidence of traumatic brain injuries in head-injured children with seizures.

Educational interventions to prevent paediatric abusive head trauma in babies younger than one year old: A systematic review and meta-analyses (2022)
Journal Article
Scott, L. J., Wilson, R., Davies, P., Lyttle, M. D., Mytton, J., Dawson, S., …Savović, J. (2022). Educational interventions to prevent paediatric abusive head trauma in babies younger than one year old: A systematic review and meta-analyses. Child Abuse and Neglect, 134, 105935. https://doi.org/10.1016/j.chiabu.2022.105935

Background: Paediatric abusive head trauma (AHT) occurs in young children due to violent shaking or blunt impact. Educational and behavioural programmes modifying parent/infant interactions may aid primary prevention. This systematic review aims to a... Read More about Educational interventions to prevent paediatric abusive head trauma in babies younger than one year old: A systematic review and meta-analyses.

Paediatric major incident triage: A Delphi process to determine clinicians' attitudes and beliefs within the United Kingdom and Ireland (2022)
Journal Article
Vassallo, J., Blakey, S., Cowburn, P., Surridge, J., Smith, J. E., Scholefield, B., …(Paediatric Emergency Research in the UK and Ireland), P. (2023). Paediatric major incident triage: A Delphi process to determine clinicians' attitudes and beliefs within the United Kingdom and Ireland. Acta Paediatrica, 112(1), 154-161. https://doi.org/10.1111/apa.16567

Aim: Triage is key to effective management of major incidents, yet there is scarce evidence surrounding the optimal method of paediatric major incident triage (MIT). This study aimed to derive consensus on key components of paediatric MIT among healt... Read More about Paediatric major incident triage: A Delphi process to determine clinicians' attitudes and beliefs within the United Kingdom and Ireland.

Features of the transposed seasonality of the 2021 RSV epidemic in the UK and Ireland: analysis of the first 10 000 patients (2022)
Journal Article
Roland, D., Williams, T., Lyttle, M. D., Marlow, R., Hardelid, P., Sinha, I., …Cunningham, S. (2022). Features of the transposed seasonality of the 2021 RSV epidemic in the UK and Ireland: analysis of the first 10 000 patients. Archives of Disease in Childhood, 107(11), 1062-1063. https://doi.org/10.1136/archdischild-2022-324241

Non-pharmaceutical interventions (NPIs) introduced globally to limit the spread of SARS-CoV-2 led to disruption of the typical respiratory syncytial virus (RSV) seasonality.1 Studies examining the resurgence of RSV have been limited by sample size an... Read More about Features of the transposed seasonality of the 2021 RSV epidemic in the UK and Ireland: analysis of the first 10 000 patients.

Presentations of children to emergency departments across Europe and the COVID-19 pandemic: A multinational observational study (2022)
Journal Article
Nijman, R. G., Honeyford, K., Farrugia, R., Rose, K., Bognar, Z., Buonsenso, D., …Titomanlio, L. (2022). Presentations of children to emergency departments across Europe and the COVID-19 pandemic: A multinational observational study. PLoS Medicine, 19(8), e1003974. https://doi.org/10.1371/journal.pmed.1003974

BACKGROUND: During the initial phase of the Coronavirus Disease 2019 (COVID-19) pandemic, reduced numbers of acutely ill or injured children presented to emergency departments (EDs). Concerns were raised about the potential for delayed and more sever... Read More about Presentations of children to emergency departments across Europe and the COVID-19 pandemic: A multinational observational study.

Diagnostic test accuracy of dipstick urinalysis for diagnosing urinary tract infection in febrile infants attending the emergency department (2022)
Journal Article
Waterfield, T., Foster, S., Platt, R., Barrett, M. J., Durnin, S., Maney, J., …Lyttle, M. D. (2022). Diagnostic test accuracy of dipstick urinalysis for diagnosing urinary tract infection in febrile infants attending the emergency department. Archives of Disease in Childhood, 107(12), 1095-1099. https://doi.org/10.1136/archdischild-2022-324300

OBJECTIVE: To report the diagnostic test accuracy of dipstick urinalysis for the detection of urinary tract infections (UTIs) in febrile infants aged 90 days or less attending the emergency department (ED). DESIGN: Retrospective cohort study. PATIENT... Read More about Diagnostic test accuracy of dipstick urinalysis for diagnosing urinary tract infection in febrile infants attending the emergency department.

Barriers to emergency department clinicians' confidence in providing paediatric trauma‐informed care (2022)
Journal Article
Afzal, N., Lyttle, M. D., Alisic, E., Trickey, D., Hiller, R. M., & Halligan, S. L. (2022). Barriers to emergency department clinicians' confidence in providing paediatric trauma‐informed care. JCPP Advances, 2(3), e12091. https://doi.org/10.1002/jcv2.12091

Abstract: Background: It has been estimated that around 31% of children will experience a traumatic event during childhood, most commonly serious accidents that lead to hospitalisation. Around 15% of children who experience such events go onto develo... Read More about Barriers to emergency department clinicians' confidence in providing paediatric trauma‐informed care.

Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation (2022)
Journal Article
Hartshorn, S., Durnin, S., Lyttle, M. D., & Barrett, M. (2022). Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation. BMJ Paediatrics Open, 6(1), Article e001273. https://doi.org/10.1136/bmjpo-2021-001273

Background Management of acute pain should commence at the earliest opportunity, as it has many short-term and long-term consequences. A research priority of Paediatric Emergency Research in the UK and Ireland (PERUKI) was to examine paediatric pain... Read More about Pain management in children and young adults with minor injury in emergency departments in the UK and Ireland: A PERUKI service evaluation.

Validating clinical practice guidelines for the management of febrile infants presenting to the emergency department in the UK and Ireland (2022)
Journal Article
Waterfield, T., Lyttle, M. D., Munday, C., Foster, S., McNulty, M., Platt, R., …Roland, D. (2022). Validating clinical practice guidelines for the management of febrile infants presenting to the emergency department in the UK and Ireland. Archives of Disease in Childhood, 107(4), 329-334. https://doi.org/10.1136/archdischild-2021-322586

Objective To report the performance of clinical practice guidelines (CPG) in the diagnosis of serious/invasive bacterial infections (SBI/IBI) in infants presenting with a fever to emergency care in the UK and Ireland. Two CPGs were from the National... Read More about Validating clinical practice guidelines for the management of febrile infants presenting to the emergency department in the UK and Ireland.

Periorbital and orbital cellulitis in children: A survey of emergency physicians and analysis of clinical practice guidelines across the PERUKI network (2022)
Journal Article
Tolhurst-Cleaver, M., Evans, J., Waterfield, T., Adamson, J., Marlow, R., Lyttle, M. D., & Roland, D. (2022). Periorbital and orbital cellulitis in children: A survey of emergency physicians and analysis of clinical practice guidelines across the PERUKI network. Emergency Medicine Journal, 39, 766-770. https://doi.org/10.1136/emermed-2021-211713

Background: Due to limited evidence to guide management of periorbital cellulitis (POC), we surveyed current practice and assessed quality and consistency of local clinical practice guidelines (CPGs) to highlight future research priorities. Methods:... Read More about Periorbital and orbital cellulitis in children: A survey of emergency physicians and analysis of clinical practice guidelines across the PERUKI network.

Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop (2022)
Journal Article
McNamara, P. S., Fernandes, R. M., Rosala-Hallas, A., Jones, A. P., Williamson, P. R., Bedson, E., …McNamara, P. S. (2022). Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop. BMJ Open, 12(3), Article e052943. https://doi.org/10.1136/bmjopen-2021-052943

Objectives The objective of this study was to develop a core outcome set (COS) for use in future clinical trials in bronchiolitis. We wanted to find out which outcomes are important to healthcare professionals (HCPs) and to parents and which outcomes... Read More about Which outcomes should be used in future bronchiolitis trials? Developing a bronchiolitis core outcome set using a systematic review, Delphi survey and a consensus workshop.

Point-of-care testing in paediatric settings in the UK and Ireland: A cross-sectional study (2022)
Journal Article
Pandey, M., Lyttle, M. D., Cathie, K., Munro, A., Waterfield, T., Roland, D., …On behalf of GAPRUKI, PERUKI. (2022). Point-of-care testing in paediatric settings in the UK and Ireland: A cross-sectional study. BMC Emergency Medicine, 22(1), Article 6. https://doi.org/10.1186/s12873-021-00556-7

Background: Point-of-care testing (POCT) is diagnostic testing performed at or near to the site of the patient. Understanding the current capacity, and scope, of POCT in this setting is essential in order to respond to new research evidence which may... Read More about Point-of-care testing in paediatric settings in the UK and Ireland: A cross-sectional study.

Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT (2021)
Journal Article
Barratt, S., Bielicki, J. A., Dunn, D., Faust, S. N., Finn, A., Harper, L., …Sharland, M. (2021). Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT. Health Technology Assessment, 25(60), 1-72. https://doi.org/10.3310/hta25600

Background: Data are limited regarding the optimal dose and duration of amoxicillin treatment for community-acquired pneumonia in children. Objectives: To determine the efficacy, safety and impact on antimicrobial resistance of shorter (3-day) and lo... Read More about Amoxicillin duration and dose for community-acquired pneumonia in children: the CAP-IT factorial non-inferiority RCT.

Effect of Amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with Community-Acquired Pneumonia: The CAP-IT randomized clinical trial (2021)
Journal Article
Bielicki, J. A., Stöhr, W., Barratt, S., Dunn, D., Naufal, N., Roland, D., …PERUKI, GAPRUKI, and the CAP-IT Trial Group. (2021). Effect of Amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with Community-Acquired Pneumonia: The CAP-IT randomized clinical trial. Journal of the American Medical Association, 326(17), 1713-1724. https://doi.org/10.1001/jama.2021.17843

Importance: The optimal dose and duration of oral amoxicillin for children with community-acquired pneumonia (CAP) are unclear. Objective: To determine whether lower-dose amoxicillin is noninferior to higher dose and whether 3-day treatment is noninf... Read More about Effect of Amoxicillin dose and treatment duration on the need for antibiotic re-treatment in children with Community-Acquired Pneumonia: The CAP-IT randomized clinical trial.

A bibliometric analysis of global pediatric emergency medicine research networks (2021)
Journal Article
Barrett, M. J., Dalziel, S., Lyttle, M., & O'Sullivan, R. (2022). A bibliometric analysis of global pediatric emergency medicine research networks. Pediatric Emergency Care, 38(4), e1179-e1184. https://doi.org/10.1097/pec.0000000000002543

Objectives During the last 3 decades newly formed pediatric emergency medicine (PEM) research networks have been publishing research. A desire of these networks is to produce and disseminate research to improve patient health and outcomes. The aims... Read More about A bibliometric analysis of global pediatric emergency medicine research networks.

Comparative analysis of major incident triage tools in children: A UK population-based analysis (2021)
Journal Article
Vassallo, J., Chernbumroong, S., Malik, N., Xu, Y., Keene, D., Gkoutos, G., …Smith, J. (2022). Comparative analysis of major incident triage tools in children: A UK population-based analysis. Emergency Medicine Journal, 39(10), 779-785. https://doi.org/10.1136/emermed-2021-211706

Introduction: Triage is a key principle in the effective management of major incidents. There is currently a paucity of evidence to guide the triage of children. The aim of this study was to perform a comparative analysis of nine adult and paediatric... Read More about Comparative analysis of major incident triage tools in children: A UK population-based analysis.

Structures of paediatric pain management: A PERUKI service evaluation study (2021)
Journal Article
Durnin, S., Barrett, M. J., Lyttle, M. D., & Hartshorn, S. (2021). Structures of paediatric pain management: A PERUKI service evaluation study. BMJ Paediatrics Open, 5(1), Article e001159. https://doi.org/10.1136/bmjpo-2021-001159

Background Pain is very common in childhood emergency department (ED) attendances, but is under-recognised and undertreated. Sequential national paediatric analgesia audits demonstrate suboptimal outcomes in several domains. The Donabedian framework... Read More about Structures of paediatric pain management: A PERUKI service evaluation study.

Retrospective observational study of neonatal attendances to a children's emergency department (2021)
Journal Article
Blakey, S. J., Lyttle, M. D., & Magnus, D. (2021). Retrospective observational study of neonatal attendances to a children's emergency department. Acta Paediatrica, 110(11), 2968-2975. https://doi.org/10.1111/apa.16039

Aim Attendances to emergency departments (EDs) in the UK are increasing, particularly for younger children. Community services are under increasing pressure and parents may preferentially bring their babies to the ED, even for non-urgent problems. T... Read More about Retrospective observational study of neonatal attendances to a children's emergency department.

Need for recovery and physician well-being in emergency departments: National survey findings (2021)
Journal Article
Cottey, L., Roberts, T., Graham, B., Horner, D., Latour, J. M., Enki, D., …Stevens, K. N. (2021). Need for recovery and physician well-being in emergency departments: National survey findings. European Journal of Emergency Medicine, 28(5), 386-393. https://doi.org/10.1097/mej.0000000000000850

Background and importance Need for recovery (NFR) describes an individual's need to physically and psychologically recuperate following a period of work. Physicians working in emergency departments (EDs) have higher NFR scores than other occupational... Read More about Need for recovery and physician well-being in emergency departments: National survey findings.

Psychological distress and trauma during the COVID-19 pandemic: survey of doctors practising anaesthesia, intensive care medicine, and emergency medicine in the United Kingdom and Republic of Ireland (2021)
Journal Article
Kane, L., Mackenzie, L., Sharma Hajela, S., Phizacklea, J., Malik, K., Mathai, N., …Carlton, E. (2021). Psychological distress and trauma during the COVID-19 pandemic: survey of doctors practising anaesthesia, intensive care medicine, and emergency medicine in the United Kingdom and Republic of Ireland. British Journal of Anaesthesia, 127(2), e78-e80. https://doi.org/10.1016/j.bja.2021.05.017

Psychological distress during the acceleration phase of the COVID-19 pandemic: A survey of doctors practising in emergency medicine, anaesthesia and intensive care medicine in the UK and Ireland (2021)
Journal Article
Roberts, T., Daniels, J., Hulme, W., Hirst, R., Horner, D., Lyttle, M. D., …Carlton, E. (2021). Psychological distress during the acceleration phase of the COVID-19 pandemic: A survey of doctors practising in emergency medicine, anaesthesia and intensive care medicine in the UK and Ireland. Emergency Medicine Journal, 38(6), 450-459. https://doi.org/10.1136/emermed-2020-210438

Objective: To quantify psychological distress experienced by emergency, anaesthetic and intensive care doctors during the acceleration phase of COVID-19 in the UK and Ireland. Methods: Initial cross-sectional electronic survey distributed during acce... Read More about Psychological distress during the acceleration phase of the COVID-19 pandemic: A survey of doctors practising in emergency medicine, anaesthesia and intensive care medicine in the UK and Ireland.

Mortality in adolescent trauma: A comparison of children's, mixed and adult major trauma centres (2021)
Journal Article
Evans, J., Murch, H., Begley, R., Roland, D., Lyttle, M. D., Bouamra, O., & Mullen, S. (2021). Mortality in adolescent trauma: A comparison of children's, mixed and adult major trauma centres. Emergency Medicine Journal, 38(7), 488-494. https://doi.org/10.1136/emermed-2020-210384

Objective: We aimed to compare adolescent mortality rates between different types of major trauma centre (MTC or level 1; adult, children's and mixed). Methods: Data were obtained from TARN (Trauma Audit Research Network) from English sites over a 6-... Read More about Mortality in adolescent trauma: A comparison of children's, mixed and adult major trauma centres.

A survey of mHealth use from a physician perspective in paediatric emergency care in the UK and Ireland (2021)
Journal Article
Jahn, H. K., Jahn, I. H. J., Behringer, W., Lyttle, M. D., & Roland, D. (2021). A survey of mHealth use from a physician perspective in paediatric emergency care in the UK and Ireland. European Journal of Pediatrics, 180, 2409–2418. https://doi.org/10.1007/s00431-021-04023-0

Abstract: There has been a drive towards increased digitalisation in healthcare. The aim was to provide a snapshot of current apps, instant messaging, and smartphone photography use in paediatric emergency care. A web-based self-report questionnaire... Read More about A survey of mHealth use from a physician perspective in paediatric emergency care in the UK and Ireland.

Ingestion of metallic foreign bodies: A Paediatric Emergency Research in the United Kingdom and Ireland survey of current practice and hand-held metal detector use (2021)
Journal Article
Lafferty, M., Lyttle, M. D., Mullen, N., & PERUKI. (2021). Ingestion of metallic foreign bodies: A Paediatric Emergency Research in the United Kingdom and Ireland survey of current practice and hand-held metal detector use. Journal of Paediatrics and Child Health, 57(6), 867-871. https://doi.org/10.1111/jpc.15343

Aim: To describe variation in the initial management of children presenting to Emergency Departments (ED) with coins lodged in the oesophagus. To determine the usage of hand-held metal detectors (HHMDs) in EDs, including their role in clinical decisi... Read More about Ingestion of metallic foreign bodies: A Paediatric Emergency Research in the United Kingdom and Ireland survey of current practice and hand-held metal detector use.

Seroprevalence of SARS-CoV-2 antibodies in children of United Kingdom healthcare workers: A prospective multicentre cohort study protocol (2020)
Journal Article
Corr, M., Christie, S., Watson, C., Maney, J., Fairley, D., Ladhani, S. N., …Waterfield, T. (2020). Seroprevalence of SARS-CoV-2 antibodies in children of United Kingdom healthcare workers: A prospective multicentre cohort study protocol. BMJ Open, 10(11), Article e041661. https://doi.org/10.1136/bmjopen-2020-041661

Background: A novel coronavirus SARS-CoV-2 has been responsible for a worldwide pandemic. Children typically have very mild, or no, symptoms of infection. This makes estimations of seroprevalence in children difficult. Research is therefore required... Read More about Seroprevalence of SARS-CoV-2 antibodies in children of United Kingdom healthcare workers: A prospective multicentre cohort study protocol.

Kinetics and seroprevalence of SARS-CoV-2 antibodies in children (2020)
Journal Article
Roarty, C., Tonry, C., McFetridge, L., Mitchell, H., Watson, C., Waterfield, T., …Christie, S. (2021). Kinetics and seroprevalence of SARS-CoV-2 antibodies in children. Lancet Infectious Diseases, 21(6), Article E143. https://doi.org/10.1016/s1473-3099%2820%2930884-7

Validating clinical practice guidelines for the management of children with non-blanching rashes in the UK (PiC): A prospective, multicentre cohort study (2020)
Journal Article
Waterfield, T., Maney, J., Fairley, D., Lyttle, M. D., McKenna, J. P., Roland, D., …Shields, M. D. (2021). Validating clinical practice guidelines for the management of children with non-blanching rashes in the UK (PiC): A prospective, multicentre cohort study. Lancet Infectious Diseases, 21(4), 569-577. https://doi.org/10.1016/S1473-3099%2820%2930474-6

Background: No previous studies have validated current clinical practice guidelines for the management of non-blanching rashes in children who have received meningococcal B and C vaccinations. The aim of this study was to evaluate the performance o... Read More about Validating clinical practice guidelines for the management of children with non-blanching rashes in the UK (PiC): A prospective, multicentre cohort study.

Seroprevalence of SARS-CoV-2 antibodies in children: A prospective multicentre cohort study (2020)
Journal Article
Waterfield, T., Watson, C., Moore, R., Ferris, K., Tonry, C., Watt, A., …Christie, S. (2021). Seroprevalence of SARS-CoV-2 antibodies in children: A prospective multicentre cohort study. Archives of Disease in Childhood, 106(7), 680-686. https://doi.org/10.1136/archdischild-2020-320558

Background: Studies based on molecular testing of oral/nasal swabs underestimate SARS-CoV-2 infection due to issues with test sensitivity, test timing and selection bias. The objective of this study was to report the presence of SARS-CoV-2 antibodies... Read More about Seroprevalence of SARS-CoV-2 antibodies in children: A prospective multicentre cohort study.

Need for recovery amongst emergency physicians in the UK and Ireland: A cross-sectional survey (2020)
Journal Article
Cottey, L., Roberts, T., Graham, B., Horner, D., Stevens, K. N., Enki, D., …Latour, J. (2020). Need for recovery amongst emergency physicians in the UK and Ireland: A cross-sectional survey. BMJ Open, 10(11), e041485. https://doi.org/10.1136/bmjopen-2020-041485

OBJECTIVES: To determine the need for recovery (NFR) among emergency physicians and to identify demographic and occupational characteristics associated with higher NFR scores. DESIGN: Cross-sectional electronic survey. SETTING: Emergency departments... Read More about Need for recovery amongst emergency physicians in the UK and Ireland: A cross-sectional survey.

National survey of feasibility of NIV trials for management of children with bronchiolitis (2020)
Journal Article
Rosala-Hallas, A., Jones, A. P., Bedson, E., Compton, V., Fernandes, R. M., Lacy, D., …McNamara, P. S. (2020). National survey of feasibility of NIV trials for management of children with bronchiolitis. BMJ Paediatrics Open, 4(1), e000780. https://doi.org/10.1136/bmjpo-2020-000780

Background Bronchiolitis is a major cause of admission to hospital in children. Non-invasive ventilation (NIV) support with continuous positive airway pressure (CPAP) or high-flow nasal cannula (HFNC) oxygen is routinely used for infants in the UK wi... Read More about National survey of feasibility of NIV trials for management of children with bronchiolitis.

Diagnostic test accuracy of point-of-care procalcitonin to diagnose serious bacterial infections in children (2020)
Journal Article
Waterfield, T., Maney, J. A., McKenna, J. P., Lyttle, M. D., Roland, D., Corr, M., …On behalf of Paediatric Emergency Research in the UK and Ireland (PERUKI). (2020). Diagnostic test accuracy of point-of-care procalcitonin to diagnose serious bacterial infections in children. BMC Pediatrics, 20(1), Article 487. https://doi.org/10.1186/s12887-020-02385-2

Background: The National Institute for Health and Care Excellence (NICE) have called for research into the role of biomarkers, and specifically procalcitonin (PCT), for the early diagnosis of serious bacterial infections (SBI) in children. The aim of... Read More about Diagnostic test accuracy of point-of-care procalcitonin to diagnose serious bacterial infections in children.

Planning for success: Overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial (2020)
Journal Article
Roper, L., Lyttle, M. D., Gamble, C., Humphreys, A., Messahel, S., Lee, E. D., …Woolfall, K. (2021). Planning for success: Overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial. Emergency Medicine Journal, 38(3), 191-197. https://doi.org/10.1136/emermed-2020-209487

Background Key challenges to the successful conduct of The Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus in children (EcLiPSE) trial were identified at the pre-trial stage. These included practitioner anxieties about condu... Read More about Planning for success: Overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial.

Fifteen minute consultation: When can I use a medical app? (2020)
Journal Article
Rowe-Setz, G., Behringer, W., Roland, D., Lyttle, M. D., & Jahn, H. K. (2021). Fifteen minute consultation: When can I use a medical app?. Archives of Disease in Childhood.education and Practice Edition, 106(5), 258-263. https://doi.org/10.1136/archdischild-2020-319448

Advances in mobile device technology and internet connectivity have created powerful new mobile health (mHealth) and telemedicine capabilities. The guidelines regarding mHealth use in the clinical environment can be conflicting, which has resulted in... Read More about Fifteen minute consultation: When can I use a medical app?.

Emergency care provided to refugee children in Europe: RefuNET: A cross-sectional survey study (2020)
Journal Article
Nijman, R. G., Krone, J., Mintegi, S., Bidlingmaier, C., Maconochie, I. K., Lyttle, M. D., & von Both, U. (2021). Emergency care provided to refugee children in Europe: RefuNET: A cross-sectional survey study. Emergency Medicine Journal, 38(1), 5-13. https://doi.org/10.1136/emermed-2019-208699

Background Refugee children and young people have complex healthcare needs. However, issues related to acute healthcare provision for refugee children across Europe remain unexplored. This study aimed to describe the urgent and emergency healthcare n... Read More about Emergency care provided to refugee children in Europe: RefuNET: A cross-sectional survey study.

Prescribing in a paediatric emergency: A PERUKI survey of prescribing and resuscitation aids (2020)
Journal Article
Jahn, H. K., Jahn, I. H. J., Roland, D., Behringer, W., Lyttle, M., & Paediatric Emergency Research in the United Kingdom, Ireland (PERUKI). (2021). Prescribing in a paediatric emergency: A PERUKI survey of prescribing and resuscitation aids. Acta Paediatrica, 110(3), 1038-1045. https://doi.org/10.1111/apa.15551

Aim: The aim was to investigate the use of paper-based and electronic prescribing and resuscitation aids in paediatric emergency care from a departmental and individual physician perspective. Methods: A two-stage web-based self-report questionnaire w... Read More about Prescribing in a paediatric emergency: A PERUKI survey of prescribing and resuscitation aids.

Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials (2020)
Journal Article
Roper, L., Lyttle, M. D., Gamble, C., Humphreys, A., Messahel, S., Lee, E. D., …Woolfall, K. (2021). Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials. Emergency Medicine Journal, 38, 198-204. https://doi.org/10.1136/emermed-2020-209488

Background: Alternatives to prospective informed consent enable the conduct of paediatric emergency and critical care trials. Research without prior consent (RWPC) involves practitioners approaching parents after an intervention has been given and se... Read More about Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials.

Risk of traumatic intracranial haemorrhage in children with bleeding disorders (2020)
Journal Article
Bressan, S., Monagle, P., Dalziel, S. R., Borland, M. L., Phillips, N., Kochar, A., …Paediatric Research in Emergency Departments International Collaborative (PREDICT). (2020). Risk of traumatic intracranial haemorrhage in children with bleeding disorders. Journal of Paediatrics and Child Health, 56(12), 1891-1897. https://doi.org/10.1111/jpc.15073

Objective: To assess computerized tomography (CT) use and the risk of intracranial haemorrhage (ICH) in children with bleeding disorders following a head trauma Design: Multicentre prospective observational study Setting: 10 paediatric emergency de... Read More about Risk of traumatic intracranial haemorrhage in children with bleeding disorders.

COVID-19 emergency response assessment study: a prospective longitudinal survey of frontline doctors in the UK and Ireland: study protocol (2020)
Journal Article
Roberts, T., Daniels, J., Hulme, W., Horner, D., Lyttle, M. D., Samuel, K., …Carlton, E. (2020). COVID-19 emergency response assessment study: a prospective longitudinal survey of frontline doctors in the UK and Ireland: study protocol. BMJ Open, 10(8), Article e039851. https://doi.org/10.1136/bmjopen-2020-039851

INTRODUCTION: The COVID-19 pandemic is putting an unprecedented strain on healthcare systems globally. The psychological impact on frontline doctors of dealing with the COVID-19 pandemic is currently unknown. This longitudinal professional survey aim... Read More about COVID-19 emergency response assessment study: a prospective longitudinal survey of frontline doctors in the UK and Ireland: study protocol.

International practice patterns of antibiotic therapy and laboratory testing in bronchiolitis (2020)
Journal Article
Zipursky, A., Kuppermann, N., Finkelstein, Y., Zemek, R., Plint, A. C., Babl, F. E., …Schuh, S. (2020). International practice patterns of antibiotic therapy and laboratory testing in bronchiolitis. Pediatrics, 146(2), https://doi.org/10.1542/peds.2019-3684

BACKGROUND AND OBJECTIVES: International patterns of antibiotic use and laboratory testing in bronchiolitis in emergency departments are unknown. Our objective is to evaluate variation in the use of antibiotics and nonindicated tests in infants with... Read More about International practice patterns of antibiotic therapy and laboratory testing in bronchiolitis.

Loop-mediated isothermal amplification for the early diagnosis of invasive meningococcal disease in children (2020)
Journal Article
Waterfield, T., Lyttle, M. D., McKenna, J., Maney, J. A., Roland, D., Corr, M., …Fairley, D. (2020). Loop-mediated isothermal amplification for the early diagnosis of invasive meningococcal disease in children. Archives of Disease in Childhood, 105(12), 1151-1156. https://doi.org/10.1136/archdischild-2020-319139

Background Rapid molecular diagnostic testing has the potential to improve the early recognition of meningococcal disease (MD). The aim of this study was to report on the diagnostic test accuracy of point-of-care loop-mediated isothermal amplificatio... Read More about Loop-mediated isothermal amplification for the early diagnosis of invasive meningococcal disease in children.

Exposure and confidence with critical non-airway procedures: A global survey of paediatric emergency medicine physicians (2020)
Journal Article
Craig, S., Auerbach, M., Cheek, J. A., Babl, F. E., Oakley, E., Nguyen, L., …Dalziel, S. R. (2021). Exposure and confidence with critical non-airway procedures: A global survey of paediatric emergency medicine physicians. Pediatric Emergency Care, 37(9), e551-e559. https://doi.org/10.1097/PEC.0000000000002092

Background: Children rarely experience critical illness, resulting in low exposure of emergency physicians (EPs) to critical procedures. Our primary objective was to describe senior EP confidence, most recent performance and/or supervision of criti... Read More about Exposure and confidence with critical non-airway procedures: A global survey of paediatric emergency medicine physicians.

The effect of patient observation on cranial computed tomography rates in children with minor head trauma (2020)
Journal Article
Singh, S., Hearps, S. J., Borland, M. L., Dalziel, S. R., Neutze, J., Donath, S., …Babl, F. E. (2020). The effect of patient observation on cranial computed tomography rates in children with minor head trauma. Academic Emergency Medicine, 27(9), 832-843. https://doi.org/10.1111/acem.13942

Background Management of children with minor blunt head trauma often includes a period of observation to determine the need for cranial computed tomography (CT). Our objective was to estimate the effect of planned observation on CT use for each Pedi... Read More about The effect of patient observation on cranial computed tomography rates in children with minor head trauma.

Acute severe paediatric asthma: Study protocol for the development of a core outcome set, a Pediatric Emergency Research Networks (PERN) study (2020)
Journal Article
Craig, S., Babl, F. E., Dalziel, S. R., Gray, C., Powell, C., Al Ansari, K., …Graudins, A. (2020). Acute severe paediatric asthma: Study protocol for the development of a core outcome set, a Pediatric Emergency Research Networks (PERN) study. Trials, 21, Article 72 (2020). https://doi.org/10.1186/s13063-019-3785-6

Background Acute severe childhood asthma is an infrequent, but potentially life-threatening emergency condition. There is a wide range of different approaches to this condition, with very little supporting evidence, leading to significant variation... Read More about Acute severe paediatric asthma: Study protocol for the development of a core outcome set, a Pediatric Emergency Research Networks (PERN) study.

Neonatal head injuries: A prospective Paediatric Research in Emergency Departments International Collaborative cohort study (2019)
Journal Article
Eapen, N., Borland, M. L., Phillips, N., Kochar, A., Dalton, S., Cheek, J. A., …Babl, F. E. (2020). Neonatal head injuries: A prospective Paediatric Research in Emergency Departments International Collaborative cohort study. Journal of Paediatrics and Child Health, 56(5), 764-769. https://doi.org/10.1111/jpc.14736

Aim To characterise the causes, clinical characteristics and short‐term outcomes of neonates who presented to paediatric emergency departments with a head injury. Methods Secondary analysis of a prospective data set of paediatric head injuries a... Read More about Neonatal head injuries: A prospective Paediatric Research in Emergency Departments International Collaborative cohort study.

Research without prior consent in paediatric emergency and critical care medicine (2019)
Journal Article
Picton, A., Woolfall, K., Lyttle, M. D., & Hartshorn, S. (2020). Research without prior consent in paediatric emergency and critical care medicine. Paediatrics and Child Health, 30(2), 74-78. https://doi.org/10.1016/j.paed.2019.11.008

Children and young peoples' healthcare should be evidence-based yet many treatments are unlicensed or prescribed off-label. Research is needed, but prospective informed consent for many emergency and critical care trials is neither feasible nor ethic... Read More about Research without prior consent in paediatric emergency and critical care medicine.

Epidemiology of adolescent trauma in England: A review of TARN data 2008-2017 (2019)
Journal Article
Roberts, Z., Collins, J. A., James, D., Bouamra, O., Young, M., Lyttle, M. D., …Mullen, S. (2019). Epidemiology of adolescent trauma in England: A review of TARN data 2008-2017. Emergency Medicine Journal, 37(1), 25-30. https://doi.org/10.1136/emermed-2018-208329

Objectives Trauma contributes significantly to adolescent morbidity and mortality. We aimed to ascertain the epidemiology of adolescent trauma to inform prevention strategies. Methods Data were abstracted from TARN (Trauma Audit Research Network... Read More about Epidemiology of adolescent trauma in England: A review of TARN data 2008-2017.

Performance of two head injury decision rules evaluated on an external cohort of 18,913 children (2019)
Journal Article
Shavit, I., Rimon, A., Waisman, Y., Borland, M. L., Phillips, N., Kochar, A., …Babl, F. E. (2020). Performance of two head injury decision rules evaluated on an external cohort of 18,913 children. Journal of Surgical Research, 245, 426-433. https://doi.org/10.1016/j.jss.2019.07.090

The Pediatric Emergency Care Applied Research Network (PECARN) decision rule demonstrates high sensitivity for identifying children at low risk for clinically important traumatic brain injury (ciTBI). As with the PECARN rule, the Israeli Decision Alg... Read More about Performance of two head injury decision rules evaluated on an external cohort of 18,913 children.

Clinically important sport‐related traumatic brain injuries in children (2019)
Journal Article
Eapen, N., Davis, G. A., Borland, M. L., Phillips, N., Oakley, E., Hearps, S., …Babl, F. E. (2019). Clinically important sport‐related traumatic brain injuries in children. The Medical journal of Australia, 211(8), 365-366. https://doi.org/10.5694/mja2.50311

Sports participation by children and adolescents is generally high in Australia and New Zealand,1, 2 and many children sustain head injuries of varying severity during such activities. Concussion has received increasing attention, but less is known a... Read More about Clinically important sport‐related traumatic brain injuries in children.

Inhaled methoxyflurane (Penthrox®) versus placebo for injury-associated analgesia in children - The MAGPIE trial (MEOF-002): Study protocol for a randomised controlled trial (2019)
Journal Article
Hartshorn, S., Barrett, M. J., Lyttle, M. D., Yee, S. A., & Irvine, A. T. (2019). Inhaled methoxyflurane (Penthrox®) versus placebo for injury-associated analgesia in children - The MAGPIE trial (MEOF-002): Study protocol for a randomised controlled trial. Trials, 20, Article 393 (2019). https://doi.org/10.1186/s13063-019-3511-4

Background Pain from injuries is one of the commonest symptoms in children attending emergency departments (EDs), and this is often inadequately treated in both the pre-hospital and ED settings, in part due to challenges of continual assessment and... Read More about Inhaled methoxyflurane (Penthrox®) versus placebo for injury-associated analgesia in children - The MAGPIE trial (MEOF-002): Study protocol for a randomised controlled trial.

Mobile device and app use in paediatric emergency care: A survey of departmental practice in the UK and Ireland (2019)
Journal Article
Jahn, H. K., Jahn, I. H., Roland, D., Lyttle, M. D., & Behringer, W. (2019). Mobile device and app use in paediatric emergency care: A survey of departmental practice in the UK and Ireland. Archives of Disease in Childhood, 104(12), 1203-1207. https://doi.org/10.1136/archdischild-2019-316872

Introduction Mobile devices and medical apps are used by healthcare professionals in adult and paediatric emergency departments worldwide. Recently, there has been a drive toward increased digitalisation especially in the UK. This point prevalence su... Read More about Mobile device and app use in paediatric emergency care: A survey of departmental practice in the UK and Ireland.

Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis (2019)
Journal Article
Woolfall, K., O'Hara, C., Deja, E., Canter, R., Khan, I., Mouncey, P., …Inwald, D. (2019). Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis. Archives of Disease in Childhood, 104(11), 1077-1082. https://doi.org/10.1136/archdischild-2019-316807

Objective: To identify parents' prioritised outcomes by combining qualitative findings from two trial feasibility studies of interventions for paediatric suspected severe infection. Design: Qualitative synthesis combining parent interview data from t... Read More about Parents’ prioritised outcomes for trials investigating treatments for paediatric severe infection: A qualitative synthesis.

Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: A retrospective analysis (2019)
Journal Article
Jamal, A., Finkelstein, Y., Kuppermann, N., Freedman, S. B., Florin, T. A., Babl, F. E., …Schuh, S. (2019). Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: A retrospective analysis. Lancet Child and Adolescent Health, 3(8), 539-547. https://doi.org/10.1016/s2352-4642%2819%2930193-2

Background Clinical guidelines advise against pharmacotherapy in bronchiolitis. However, little is known about global variation in prescribing practices for bronchiolitis at discharge from emergency departments. We aimed to evaluate global variation... Read More about Pharmacotherapy in bronchiolitis at discharge from emergency departments within the Pediatric Emergency Research Networks: A retrospective analysis.

Parents' and clinicians' views on conducting paediatric diagnostic test accuracy studies without prior informed consent: Qualitative insight from the Petechiae in Children study (PiC) (2019)
Journal Article
Waterfield, T., Lyttle, M. D., Shields, M., Fairley, D., Roland, D., McKenna, J., & Woolfall, K. (2019). Parents' and clinicians' views on conducting paediatric diagnostic test accuracy studies without prior informed consent: Qualitative insight from the Petechiae in Children study (PiC). Archives of Disease in Childhood, 104(10), 979-983. https://doi.org/10.1136/archdischild-2019-317117

Objective: The Petechiae in Children (PiC) study assesses the utility of presenting features and rapid diagnostic tests in the diagnosis of serious bacterial infection in feverish children with non-blanching rashes. An embedded qualitative study expl... Read More about Parents' and clinicians' views on conducting paediatric diagnostic test accuracy studies without prior informed consent: Qualitative insight from the Petechiae in Children study (PiC).

Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia: A protocol for a randomIsed controlled Trial (CAP-IT) (2019)
Journal Article
Lyttle, M. D., Bielicki, J. A., Barratt, S., Dunn, D., Finn, A., Harper, L., …Sharland, M. (2019). Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia: A protocol for a randomIsed controlled Trial (CAP-IT). BMJ Open, 9(5), e029875. https://doi.org/10.1136/bmjopen-2019-029875

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. Introduction Community-acquired pneumonia (CAP) is a common indication for antibiotic treatment in young children. Data are limited regarding the ideal dose and... Read More about Efficacy, safety and impact on antimicrobial resistance of duration and dose of amoxicillin treatment for young children with Community-Acquired Pneumonia: A protocol for a randomIsed controlled Trial (CAP-IT).

Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial (2019)
Journal Article
Crome, L., Nyirenda, M., Sajjanhar, T., Leighton, S., McLellan, S., Bell, C., …Lyttle, M. D. (2019). Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial. Lancet, 393(10186), 2125-2134. https://doi.org/10.1016/S0140-6736%2819%2930724-X

Background Phenytoin is the recommended second-line intravenous anticonvulsant for treatment of paediatric convulsive status epilepticus in the UK; however, some evidence suggests that levetiracetam could be an effective and safer alternative. This... Read More about Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial.

Enhancing practitioners’ confidence in recruitment and consent in the EcLiPSE trial: A mixed-method evaluation of site training – a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study (2019)
Journal Article
Woolfall, K., Roper, L., Humphreys, A., Lyttle, M. D., Messahel, S., Lee, E., …Appleton, R. (2019). Enhancing practitioners’ confidence in recruitment and consent in the EcLiPSE trial: A mixed-method evaluation of site training – a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study. Trials, 20, Article 181. https://doi.org/10.1186/s13063-019-3273-z

Background: EcLiPSE (Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus in children) is a randomised controlled trial (RCT) in the United Kingdom. Challenges to success include the need to immediately administer an intervention... Read More about Enhancing practitioners’ confidence in recruitment and consent in the EcLiPSE trial: A mixed-method evaluation of site training – a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study.

Traumatic brain injury in young children with isolated scalp haematoma (2019)
Journal Article
Bressan, S., Kochar, A., Oakley, E., Borland, M., Phillips, N., Dalton, S., …Babl, F. E. (2019). Traumatic brain injury in young children with isolated scalp haematoma. Archives of Disease in Childhood, 104(7), 664-669. https://doi.org/10.1136/archdischild-2018-316066

Objective Despite high-quality paediatric head trauma clinical prediction rules, the management of otherwise asymptomatic young children with scalp haematomas (SH) can be difficult. We determined the risk of intracranial injury when SH is the only pr... Read More about Traumatic brain injury in young children with isolated scalp haematoma.

Incidence of medically attended paediatric burns across the UK (2019)
Journal Article
Davies, K., Johnson, E. L., Hollén, L., Jones, H. M., Lyttle, M. D., Maguire, S., & Kemp, A. M. (2020). Incidence of medically attended paediatric burns across the UK. Injury Prevention, 26(1), 24-30. https://doi.org/10.1136/injuryprev-2018-042881

Objective: Childhood burns represent a burden on health services, yet the full extent of the problem is difficult to quantify. We estimated the annual UK incidence from primary care (PC), emergency attendances (EA), hospital admissions (HA) and death... Read More about Incidence of medically attended paediatric burns across the UK.

Canadian and UK/Ireland practice patterns in lumbar puncture performance in febrile neonates with bronchiolitis (2019)
Journal Article
Simone, L., Lyttle, M. D., Roland, D., Stephens, D., & Schuh, S. (2019). Canadian and UK/Ireland practice patterns in lumbar puncture performance in febrile neonates with bronchiolitis. Emergency Medicine Journal, 36(3), 148-153. https://doi.org/10.1136/emermed-2018-208000

Background Serious bacterial infections in young infants with bronchiolitis are rare. Febrile infants

Delayed presentations to emergency departments of children with head injury: A PREDICT study (2019)
Journal Article
Borland, M. L., Dalziel, S. R., Phillips, N., Lyttle, M. D., Bressan, S., Oakley, E., …Babl, F. E. (2019). Delayed presentations to emergency departments of children with head injury: A PREDICT study. Annals of Emergency Medicine, 74(1), 1-10. https://doi.org/10.1016/j.annemergmed.2018.11.035

© 2018 American College of Emergency Physicians Study objective: Existing clinical decision rules guide management for head-injured children presenting 24 hours or sooner after injury, even though some may present greater than 24 hours afterward. We... Read More about Delayed presentations to emergency departments of children with head injury: A PREDICT study.

Paediatric intentional head injuries in the emergency department: A multicentre prospective cohort study (2018)
Journal Article
Lyttle, M. D., Babl, F. E., Pfeiffer, H., Dalziel, S. R., Oakley, E., Anderson, V., …Crowe, L. (2019). Paediatric intentional head injuries in the emergency department: A multicentre prospective cohort study. Emergency Medicine Australasia, 31(4), 546-554. https://doi.org/10.1111/1742-6723.13202

© 2018 Australasian College for Emergency Medicine Objective: Although there is a large body of research on head injury (HI) inflicted by caregivers in young children, little is known about intentional HI in older children and inflicted HI by perpetr... Read More about Paediatric intentional head injuries in the emergency department: A multicentre prospective cohort study.

A cost-effectiveness analysis comparing clinical decision rules PECARN, CATCH, and CHALICE with usual care for the management of pediatric head injury (2018)
Journal Article
Dalziel, K., Cheek, J. A., Fanning, L., Borland, M. L., Phillips, N., Kochar, A., …Babl, F. E. (2019). A cost-effectiveness analysis comparing clinical decision rules PECARN, CATCH, and CHALICE with usual care for the management of pediatric head injury. Annals of Emergency Medicine, 73(5), 429-439. https://doi.org/10.1016/j.annemergmed.2018.09.030

© 2018 American College of Emergency Physicians Study objective: To determine the cost-effectiveness of 3 clinical decision rules in comparison to Australian and New Zealand usual care: the Children's Head Injury Algorithm for the Prediction of Impor... Read More about A cost-effectiveness analysis comparing clinical decision rules PECARN, CATCH, and CHALICE with usual care for the management of pediatric head injury.

Defining significant childhood illness and injury in the Emergency Department: A consensus of UK and Ireland expert opinion (2018)
Journal Article
Lillitos, P. J., Lyttle, M. D., Roland, D., Powell, C. V., Sandell, J., Rowland, A. G., …Maconochie, I. K. (2018). Defining significant childhood illness and injury in the Emergency Department: A consensus of UK and Ireland expert opinion. Emergency Medicine Journal, 35(11), 685-690. https://doi.org/10.1136/emermed-2018-207802

© Author(s) (or their employer(s)) 2018. No commercial re-use. See rights and permissions. Published by BMJ. Background Clarifying whether paediatric early warning scores (PEWS) accurately predict significant illness is a research priority for UK and... Read More about Defining significant childhood illness and injury in the Emergency Department: A consensus of UK and Ireland expert opinion.

Preferred learning modalities and practice for critical skills: A global survey of paediatric emergency medicine clinicians (2018)
Journal Article
Craig, S. S., Auerbach, M., Cheek, J. A., Babl, F. E., Oakley, E., Nguyen, L., …Dalziel, S. R. (2019). Preferred learning modalities and practice for critical skills: A global survey of paediatric emergency medicine clinicians. Emergency Medicine Journal, 36(5), 273-280. https://doi.org/10.1136/emermed-2017-207384

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ. Objective To describe senior paediatric emergency clinician perspectives on the optimal frequency of and preferred modalities for practising... Read More about Preferred learning modalities and practice for critical skills: A global survey of paediatric emergency medicine clinicians.

External validation of the Scandinavian guidelines for management of minimal, mild and moderate head injuries in children (2018)
Journal Article
Undén, J., Dalziel, S. R., Borland, M. L., Phillips, N., Kochar, A., Lyttle, M. D., …Babl, F. E. (2018). External validation of the Scandinavian guidelines for management of minimal, mild and moderate head injuries in children. BMC Medicine, 16(1), https://doi.org/10.1186/s12916-018-1166-8

© 2018 The Author(s). Background: Clinical decision rules (CDRs) aid in the management of children with traumatic brain injury (TBI). Recently, the Scandinavian Neurotrauma Committee (SNC) has published practical, evidence-based guidelines for childr... Read More about External validation of the Scandinavian guidelines for management of minimal, mild and moderate head injuries in children.

A Longitudinal Examination of the Relationship between Trauma-Related Cognitive Factors and Internalising and Externalising Psychopathology in Physically Injured Children (2018)
Journal Article
Hiller, R. M., Creswell, C., Meiser-Stedman, R., Lobo, S., Cowdrey, F., Lyttle, M. D., …Halligan, S. L. (2019). A Longitudinal Examination of the Relationship between Trauma-Related Cognitive Factors and Internalising and Externalising Psychopathology in Physically Injured Children. Journal of Abnormal Child Psychology, 47(4), 683-693. https://doi.org/10.1007/s10802-018-0477-8

© 2018, The Author(s). Cognitive models of posttraumatic stress disorder (PTSD) highlight maladaptive posttrauma appraisals, trauma memory qualities, and coping strategies, such as rumination or thought suppression, as key processes that maintain PTS... Read More about A Longitudinal Examination of the Relationship between Trauma-Related Cognitive Factors and Internalising and Externalising Psychopathology in Physically Injured Children.

Epidemiology and aetiology of paediatric traumatic cardiac arrest in England and Wales (2018)
Journal Article
Vassallo, J., Webster, M., Barnard, E. B. G., Lyttle, M. D., & Smith, J. E. (2019). Epidemiology and aetiology of paediatric traumatic cardiac arrest in England and Wales. Archives of Disease in Childhood, 104(5), 437-443. https://doi.org/10.1136/archdischild-2018-314985

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ. Objective To describe the epidemiology and aetiology of paediatric traumatic cardiac arrest (TCA) in England and Wales. Design Population-bas... Read More about Epidemiology and aetiology of paediatric traumatic cardiac arrest in England and Wales.

Paediatric traumatic cardiac arrest: The development of an algorithm to guide recognition, management and decisions to terminate resuscitation (2018)
Journal Article
Vassallo, J., Nutbeam, T., Rickard, A. C., Lyttle, M. D., Scholefield, B., Maconochie, I. K., & Smith, J. E. (2018). Paediatric traumatic cardiac arrest: The development of an algorithm to guide recognition, management and decisions to terminate resuscitation. Emergency Medicine Journal, 35(11), 669-674. https://doi.org/10.1136/emermed-2018-207739

© Author(s) (or their employer(s)) 2018. No commercial re-use. See rights and permissions. Published by BMJ. Introduction Paediatric traumatic cardiac arrest (TCA) is a high acuity, low frequency event. Traditionally, survival from TCA has been repor... Read More about Paediatric traumatic cardiac arrest: The development of an algorithm to guide recognition, management and decisions to terminate resuscitation.

Accuracy of NEXUS II head injury decision rule in children: A prospective PREDICT cohort study (2018)
Journal Article
Babl, F. E., Oakley, E., Dalziel, S. R., Borland, M. L., Phillips, N., Kochar, A., …Lyttle, M. D. (2019). Accuracy of NEXUS II head injury decision rule in children: A prospective PREDICT cohort study. Emergency Medicine Journal, 36(1), 4-11. https://doi.org/10.1136/emermed-2017-207435

© 2019 Author(s). Objective The National Emergency X-Radiography Utilisation Study II (NEXUS II) clinical decision rule (CDR) can be used to optimise the use of CT in children with head trauma. We set out to externally validate this CDR in a large co... Read More about Accuracy of NEXUS II head injury decision rule in children: A prospective PREDICT cohort study.

Criteria led discharge of wheezy children from a short stay assessment unit (2018)
Journal Article
Armstrong, L., & Lyttle, M. D. (2019). Criteria led discharge of wheezy children from a short stay assessment unit. Archives of Disease in Childhood.education and Practice Edition, 104(6), Article 315056. https://doi.org/10.1136/archdischild-2018-315056

Implementation and evaluation of criteria led discharge from a Short Stay Assessment unit (SSU) for children with wheeze.

Restricted fluid bolus volume in early septic shock: Results of the Fluids in Shock pilot trial (2018)
Journal Article
Inwald, D., Canter, R., Woolfall, K., Mouncey, P., Zenasni, Z., O'Hara, C., …Rowan, K. (2019). Restricted fluid bolus volume in early septic shock: Results of the Fluids in Shock pilot trial. Archives of Disease in Childhood, 104(5), 426-431. https://doi.org/10.1136/archdischild-2018-314924

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. Objective To determine the feasibility of Fluids in Shock, a randomised controlled trial (RCT) of restricted fluid bolus volume (10 mL/kg) versus recommended pra... Read More about Restricted fluid bolus volume in early septic shock: Results of the Fluids in Shock pilot trial.

The "Petechiae in children" (PiC) study: Evaluating potential clinical decision rules for the management of feverish children with non-blanching rashes, including the role of point of care testing for Procalcitonin & Neisseria meningitidis DNA - a study protocol (2018)
Journal Article
Waterfield, T., Lyttle, M., Fairley, D., Mckenna, J., Woolfall, K., Lynn, F., …Shields, M. D. (2018). The "Petechiae in children" (PiC) study: Evaluating potential clinical decision rules for the management of feverish children with non-blanching rashes, including the role of point of care testing for Procalcitonin & Neisseria meningitidis DNA - a study protocol. BMC Pediatrics, 18(1), https://doi.org/10.1186/s12887-018-1220-x

© 2018 The Author(s). Background: Children commonly present to Emergency Departments (ED) with a non-blanching rash in the context of a feverish illness. While most have a self-limiting viral illness, this combination of features potentially represen... Read More about The "Petechiae in children" (PiC) study: Evaluating potential clinical decision rules for the management of feverish children with non-blanching rashes, including the role of point of care testing for Procalcitonin & Neisseria meningitidis DNA - a study protocol.

Comparing the usability of paediatric weight estimation methods: A simulation study (2018)
Journal Article
Marlow, R. D., Wood, D. L., & Lyttle, M. D. (2019). Comparing the usability of paediatric weight estimation methods: A simulation study. Archives of Disease in Childhood, 104(2), 121-123. https://doi.org/10.1136/archdischild-2018-314873

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ. Objective Estimating weight is essential in order to prepare appropriate sized equipment and doses of resuscitation drugs in cases where chil... Read More about Comparing the usability of paediatric weight estimation methods: A simulation study.

External validation of the PediBIRN clinical prediction rule for abusive head trauma (2018)
Journal Article
Pfeiffer, H., Smith, A., Kemp, A. M., Cowley, L. E., Cheek, J. A., Dalziel, S. R., …Babl, F. E. (2018). External validation of the PediBIRN clinical prediction rule for abusive head trauma. Pediatrics, 141(5), e20173674. https://doi.org/10.1542/peds.2017-3674

© Copyright 2018 by the American Academy of Pediatrics. BACKGROUND AND OBJECTIVES: A 4-variable abusive head trauma (AHT) clinical prediction rule (CPR) for use in the PICU was derived and validated for children

Paediatric traumatic cardiac arrest: A Delphi study to establish consensus on definition and management (2018)
Journal Article
Rickard, A. C., Vassallo, J., Nutbeam, T., Lyttle, M., Maconochie, I. K., Enki, D. G., & Smith, J. E. (2018). Paediatric traumatic cardiac arrest: A Delphi study to establish consensus on definition and management. Emergency Medicine Journal, 35(7), 434-439. https://doi.org/10.1136/emermed-2017-207226

Aims Paediatric traumatic cardiac arrest (TCA) is associated with low survival and poor outcomes. The mechanisms that underlie TCA are different from medical cardiac arrest; the approach to treatment of TCA may therefore also need to differ to optimi... Read More about Paediatric traumatic cardiac arrest: A Delphi study to establish consensus on definition and management.

Vomiting with head trauma and risk of traumatic brain injury (2018)
Journal Article
Furyk, J., Kochar, A., Hearps, S. J., Oakley, E., Bressan, S., Lyttle, M. D., …Babl, F. (2018). Vomiting with head trauma and risk of traumatic brain injury. Pediatrics, 141(4), e20173123. https://doi.org/10.1542/peds.2017-3123

© 2018 by the American Academy of Pediatrics. OBJECTIVES: To determine the prevalence of traumatic brain injuries in children who vomit after head injury and identify variables from published clinical decision rules (CDRs) that predict increased risk... Read More about Vomiting with head trauma and risk of traumatic brain injury.

Penetrating head injuries in children presenting to the emergency department in Australia and New Zealand: A PREDICT prospective study (2018)
Journal Article
Babl, F., Lyttle, M., Bressan, S., Borland, M., Phillips, N., Kochar, A., …Oakley, E. (2018). Penetrating head injuries in children presenting to the emergency department in Australia and New Zealand: A PREDICT prospective study. Journal of Paediatrics and Child Health, 54(8), 861-865. https://doi.org/10.1111/jpc.13903

© 2018 Paediatrics and Child Health Division (The Royal Australasian College of Physicians) Aim: Penetrating head injuries (pHIs) are associated with high morbidity and mortality. Data on pHIs in children outside North America are limited. We describ... Read More about Penetrating head injuries in children presenting to the emergency department in Australia and New Zealand: A PREDICT prospective study.

Fifteen-minute consultation: The child with a non-blanching rash (2018)
Journal Article
Waterfield, T., Dyer, E. M., & Lyttle, M. (2018). Fifteen-minute consultation: The child with a non-blanching rash. Archives of Disease in Childhood.education and Practice Edition, 103(5), 236-240. https://doi.org/10.1136/archdischild-2017-313998

Its 2am and you are called to review a “well looking child” in the emergency department who has presented with a new non-blanching rash. He has been hot at home with some coryzal symptoms. Mum is worried, she thinks the rash has spread in the last... Read More about Fifteen-minute consultation: The child with a non-blanching rash.

Accuracy of Clinician Practice Compared With Three Head Injury Decision Rules in Children: A Prospective Cohort Study (2018)
Journal Article
Babl, F. E., Oakley, E., Dalziel, S. R., Borland, M. L., Phillips, N., Kochar, A., …Lyttle, M. (2018). Accuracy of Clinician Practice Compared With Three Head Injury Decision Rules in Children: A Prospective Cohort Study. Annals of Emergency Medicine, 71(6), 703-710. https://doi.org/10.1016/j.annemergmed.2018.01.015

© 2018 American College of Emergency Physicians Study objective: Three clinical decision rules for head injuries in children (Pediatric Emergency Care Applied Research Network [PECARN], Canadian Assessment of Tomography for Childhood Head Injury [CAT... Read More about Accuracy of Clinician Practice Compared With Three Head Injury Decision Rules in Children: A Prospective Cohort Study.

Investigating the Variability in Mild Traumatic Brain Injury Definitions: A Prospective Cohort Study (2018)
Journal Article
Crowe, L. M., Hearps, S., Anderson, V., Borland, M., Phillips, N., Kochar, A., …Babl, F. E. (2018). Investigating the Variability in Mild Traumatic Brain Injury Definitions: A Prospective Cohort Study. Archives of Physical Medicine and Rehabilitation, 99(7), 1360-1369. https://doi.org/10.1016/j.apmr.2017.12.026

© 2018 American Congress of Rehabilitation Medicine Objective: To prospectively compare the proportion of traumatic brain injuries (TBIs) that would be classified as mild by applying different published definitions of mild TBI to a large prospectivel... Read More about Investigating the Variability in Mild Traumatic Brain Injury Definitions: A Prospective Cohort Study.

Knowledge and training in paediatric medical traumatic stress and trauma-informed care among emergency medical professionals in low- and middle-income countries (2018)
Journal Article
Hoysted, C., Parri, N., Babl, F., Lyttle, M., & Alisic, E. (2018). Knowledge and training in paediatric medical traumatic stress and trauma-informed care among emergency medical professionals in low- and middle-income countries. European Journal of Psychotraumatology, 9(1), https://doi.org/10.1080/20008198.2018.1468703

© 2018, © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Background: Provision of psychosocial care, in particular trauma-informed care, in the immediate aftermath of paediatric injury is a recommended strat... Read More about Knowledge and training in paediatric medical traumatic stress and trauma-informed care among emergency medical professionals in low- and middle-income countries.

54 Paediatric traumatic cardiac arrest in England and Wales a 10 year epidemiological study (2017)
Journal Article
Vassallo, J., Webster, M., Barnard, E., Iniguez, M. F., Lyttle, M., & Smith, J. (2017). 54 Paediatric traumatic cardiac arrest in England and Wales a 10 year epidemiological study. Emergency Medicine Journal, 34(12), A897-A899. https://doi.org/10.1136/emermed-2017-207308.54

© 2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. INTRODUCTION: Traumatic cardiac arrest (TCA) has traditiona... Read More about 54 Paediatric traumatic cardiac arrest in England and Wales a 10 year epidemiological study.

49 Paediatric traumatic cardiac arrest - the development of a treatment algorithm (2017)
Journal Article
Vassallo, J., Nutbeam, T., Rickard, A., Lyttle, M., & Smith, J. (2017). 49 Paediatric traumatic cardiac arrest - the development of a treatment algorithm. Emergency Medicine Journal, 34(12), A892-A894. https://doi.org/10.1136/emermed-2017-207308.49

© 2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. INTRODUCTION: Paediatric Traumatic Cardiac Arrest (TCA) is... Read More about 49 Paediatric traumatic cardiac arrest - the development of a treatment algorithm.

Practice variation in acute bronchiolitis: A pediatric emergency research networks study (2017)
Journal Article
Van De Voorde, P., Roland, D., Lyttle, M. D., Nigrovic, L., Mistry, R., Mintegi, S., …Kuppermann, N. (2017). Practice variation in acute bronchiolitis: A pediatric emergency research networks study. Pediatrics, 140(6), e20170842. https://doi.org/10.1542/peds.2017-0842

© Copyright 2017 by the American Academy of Pediatrics. BACKGROUND AND OBJECTIVES: Studies characterizing hospitalizations in bronchiolitis did not identify patients receiving evidence-based supportive therapies (EBSTs). We aimed to evaluate intersit... Read More about Practice variation in acute bronchiolitis: A pediatric emergency research networks study.

51 Paediatric emergency clinicians are rarely exposed to non-airway critical procedures: a predict/PERN study (2017)
Journal Article
Garrahan, J. P., Lyttle, M., Oakley, E., Dalziel, S., Nguyen, L., Rao, A., …Babl, F. (2017). 51 Paediatric emergency clinicians are rarely exposed to non-airway critical procedures: a predict/PERN study. Emergency Medicine Journal, 34(12), A894-A895. https://doi.org/10.1136/emermed-2017-207308.51

© 2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. BACKGROUND: Recent studies suggest that approximately one p... Read More about 51 Paediatric emergency clinicians are rarely exposed to non-airway critical procedures: a predict/PERN study.

Guidelines for the use of chest radiographs in community-acquired pneumonia in children and adolescents (2017)
Journal Article
Andronikou, S., Lambert, E., Halton, J., Hilder, L., Crumley, I., Lyttle, M., & Kosack, C. (2017). Guidelines for the use of chest radiographs in community-acquired pneumonia in children and adolescents. Pediatric Radiology, 47(11), 1405-1411. https://doi.org/10.1007/s00247-017-3944-4

© 2017, The Author(s). National guidance from the United Kingdom and the United States on community-acquired pneumonia in children states that chest radiographs are not recommended routinely in uncomplicated cases. The main reason in the ambulatory s... Read More about Guidelines for the use of chest radiographs in community-acquired pneumonia in children and adolescents.

A qualitative feasibility study to inform a randomised controlled trial of fluid bolus therapy in septic shock (2017)
Journal Article
Rowan, K. M., Harrison, D. A., Peters, M. J., Nadel, S., Jones, N., O'Hara, C., …Woolfall, K. (2018). A qualitative feasibility study to inform a randomised controlled trial of fluid bolus therapy in septic shock. Archives of Disease in Childhood, 103(1), 28-32. https://doi.org/10.1136/archdischild-2016-312515

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. Objective The Fluids in Shock (FiSh) Trial proposes to evaluate whether restrictive fluid bolus therapy (10 mL/ kg) is more benef... Read More about A qualitative feasibility study to inform a randomised controlled trial of fluid bolus therapy in septic shock.

Perspectives of hospital emergency department staff on trauma-informed care for injured children: An Australian and New Zealand analysis (2017)
Journal Article
Kharbanda, A. B., Landolt, M. A., Babl, F. E., Hoysted, C., Babl, F. E., Kassam-Adams, N., …Alisic, E. (2017). Perspectives of hospital emergency department staff on trauma-informed care for injured children: An Australian and New Zealand analysis. Journal of Paediatrics and Child Health, 53(9), 862-869. https://doi.org/10.1111/jpc.13644

© 2017 Paediatrics and Child Health Division (The Royal Australasian College of Physicians) Aim: To examine Australian and New Zealand emergency department (ED) staff's training, knowledge and confidence regarding trauma-informed care for children af... Read More about Perspectives of hospital emergency department staff on trauma-informed care for injured children: An Australian and New Zealand analysis.

Diagnostic accuracy of the NEXUS II head injury clinical decision rule in children. A PREDICT prospective cohort study (2017)
Journal Article
Babl, F., Borland, M., Phillips, N., Kochar, A., Dalton, S., Cheek, J., …Lyttle, M. (2017). Diagnostic accuracy of the NEXUS II head injury clinical decision rule in children. A PREDICT prospective cohort study. Archives of Disease in Childhood, 102(S1), A115-A115. https://doi.org/10.1136/archdischild-2017-313087.286

Aims Clinical decision rules (CDRs) can be applied in Emergency Departments (EDs) to optimise the use of computed tomography (CT) in children with head trauma. The National Emergency X- Radiography Utilisation Study II (NEXUS II) CDR, as amended for... Read More about Diagnostic accuracy of the NEXUS II head injury clinical decision rule in children. A PREDICT prospective cohort study.

Defining mild traumatic brain injury: How classification differs across studies when applied to a large prospective data set. A PREDICT prospective cohort study (2017)
Journal Article
Crowe, L., Lyttle, M., Hearps, S., Anderson, V., Borland, M., Phillips, N., …Babl, F. (2017). Defining mild traumatic brain injury: How classification differs across studies when applied to a large prospective data set. A PREDICT prospective cohort study. Archives of Disease in Childhood, 102(S1), A115-A115. https://doi.org/10.1136/archdischild-2017-313087.287

Aims Mild traumatic brain injury (TBI) in children is a major public health issue, yet there is wide variation in the way ‘mild’ TBI is defined in the literature and in guidelines. To date no study has prospectively detailed the proportion of childre... Read More about Defining mild traumatic brain injury: How classification differs across studies when applied to a large prospective data set. A PREDICT prospective cohort study.

Confirmation of traumatic cardiac arrest in children: A literature review to inform the peruki ptca consensus study (2017)
Journal Article
Ledger, E., & Lyttle, M. (2017). Confirmation of traumatic cardiac arrest in children: A literature review to inform the peruki ptca consensus study. Archives of Disease in Childhood, 102(S1), A118-A118. https://doi.org/10.1136/archdischild-2017-313087.293

Aims Traumatic cardiac arrest (TCA) is associated with high mortality and poor neurological outcomes. Several methods of confirming cardiac arrest are utilised including auscultation of heart sounds, palpation of pulses and echocardiography. We did a... Read More about Confirmation of traumatic cardiac arrest in children: A literature review to inform the peruki ptca consensus study.

Accuracy of physician practice as compared with PECARN, CATCH and CHALICE head injury clinical decision rules in children. A PREDICT prospective cohort study (2017)
Journal Article
Lyttle, M., Borland, M., Phillips, N., Kochar, A., Cheek, J., Gilhotra, Y., …Babl, F. (2017). Accuracy of physician practice as compared with PECARN, CATCH and CHALICE head injury clinical decision rules in children. A PREDICT prospective cohort study. Archives of Disease in Childhood, 102(S1), A107-A108. https://doi.org/10.1136/archdischild-2017-313087.267

Aims Clinical decision rules (CDRs) can assist in determining the need for computed tomography (CT) in children with head injuries (HIs). We assessed the accuracy of 3 high quality CDRs (PECARN, CATCH and CHALICE) in a large prospective cohort of hea... Read More about Accuracy of physician practice as compared with PECARN, CATCH and CHALICE head injury clinical decision rules in children. A PREDICT prospective cohort study.

Paediatric intentional head injuriesin the emergency department. A PREDICT multicentre prospective cohort study (2017)
Journal Article
Pfeiffer, H., Borland, M., Phillips, N., Kochar, A., Dalton, S., Cheek, J., …Babl, F. (2017). Paediatric intentional head injuriesin the emergency department. A PREDICT multicentre prospective cohort study. Archives of Disease in Childhood, 102(S1), A117-A117. https://doi.org/10.1136/archdischild-2017-313087.291

Aims While the majority of head injuries (HIs) in children are non-intentional, there is limited information on intentional HIs outside abusive head trauma. The objective of this study was to describe epidemiology, demographics and severity of intent... Read More about Paediatric intentional head injuriesin the emergency department. A PREDICT multicentre prospective cohort study.

Paediatric traumatic cardiac arrest– A Delphi study to establish consensus on management. A PERUKI study (2017)
Journal Article
Rickard, A., Vassallo, J., Nutbeam, T., Maconochie, I., Lyttle, M., & Smith, J. (2017). Paediatric traumatic cardiac arrest– A Delphi study to establish consensus on management. A PERUKI study. Archives of Disease in Childhood, 102(S1), A108-A108. https://doi.org/10.1136/archdischild-2017-313087.268

Background Paediatric traumatic cardiac arrest (TCA) is associated with low survival and poor outcomes. The mechanisms that underlie TCA are different from medical cardiac arrest; the approach to treatment of TCA may therefore also need to differ to... Read More about Paediatric traumatic cardiac arrest– A Delphi study to establish consensus on management. A PERUKI study.

Epidemiology and aetiology of paediatric traumatic cardiac arrest in england and wales, a peruki study (2017)
Journal Article
Vassallo, J., Webster, M., Barnard, E., Fragoso-Iñiguez, M., Lyttle, M., & Smith, J. (2017). Epidemiology and aetiology of paediatric traumatic cardiac arrest in england and wales, a peruki study. Archives of Disease in Childhood, 102(S1), A116-A116. https://doi.org/10.1136/archdischild-2017-313087.289

Background Traumatic cardiac arrest (TCA) in children has traditionally been described as having a poor outcome. Survival rates vary widely between studies with higher rates observed from mechanisms leading to a respiratory cause of TCA (e.g. drownin... Read More about Epidemiology and aetiology of paediatric traumatic cardiac arrest in england and wales, a peruki study.

Emergency treatment with levetiracetam or phenytoin in status epilepticus in children-the EcLiPSE study: Study protocol for a randomised controlled trial (2017)
Journal Article
Bacon, N. E., Lyttle, M., Gamble, C., Messahel, S., Hickey, H., Iyer, A., …Appleton, R. E. (2017). Emergency treatment with levetiracetam or phenytoin in status epilepticus in children-the EcLiPSE study: Study protocol for a randomised controlled trial. Trials, 18(1), https://doi.org/10.1186/s13063-017-2010-8

© The Author(s). 2017. Background: Convulsive status epilepticus (CSE) is the most common life-threatening neurological emergency in childhood. These children are also at risk of significant morbidity, with acute and chronic impact on the family and... Read More about Emergency treatment with levetiracetam or phenytoin in status epilepticus in children-the EcLiPSE study: Study protocol for a randomised controlled trial.

Ten concerns about blood pressure measurement and targets in paediatric sepsis (2016)
Journal Article
Lyttle, M. D., Marlais, M., Lyttle, M., & Inwald, D. (2017). Ten concerns about blood pressure measurement and targets in paediatric sepsis. Intensive Care Medicine, 43(3), 433-435. https://doi.org/10.1007/s00134-016-4642-7

Current paediatric sepsis guidelines suggest that resuscitation is titrated against clinical markers of hypovolaemia and end organ perfusion [1], including blood pressure (BP), heart rate and capillary refill time (CRT). BP is used both as a defining... Read More about Ten concerns about blood pressure measurement and targets in paediatric sepsis.

A qualitative feasibility study to inform Fluids in Shock (FISH) - a pilot randomised controlled trial of fluid bolus therapy in septic shock (2016)
Journal Article
O'Hara, C., Woolfall, K., Canter, R., Mouncey, P., Rowan, K., Lyttle, M., …Nadel, S. (2016). A qualitative feasibility study to inform Fluids in Shock (FISH) - a pilot randomised controlled trial of fluid bolus therapy in septic shock. Emergency Medicine Journal, 33(12), 902.1-902. https://doi.org/10.1136/emermed-2016-206402.7

Objectives & Background There is increasing evidence that fluid overload may be associated with harm in paediatric critical illness. Fluids in Shock (FiSH) is a combined feasibility and pilot randomised controlled trial (RCT) to determine if restric... Read More about A qualitative feasibility study to inform Fluids in Shock (FISH) - a pilot randomised controlled trial of fluid bolus therapy in septic shock.

Emergency department re-attendances and treatment modifications in young children with uncomplicated community-acquired pneumonia: A PERUKI study (2016)
Journal Article
Bielicki, J., Sharland, M., Lyttle, M., Hartshorn, S., & Petrie, J. (2016). Emergency department re-attendances and treatment modifications in young children with uncomplicated community-acquired pneumonia: A PERUKI study. Emergency Medicine Journal, 33(12), 933.3-934. https://doi.org/10.1136/emermed-2016-206402.62

Objectives & Background Data on the rate of antibiotic retreatment in children with uncomplicated community-acquired pneumonia (CAP) are lacking. We conducted a service evaluation of CAP management to review assumptions for a large UK-based trial p... Read More about Emergency department re-attendances and treatment modifications in young children with uncomplicated community-acquired pneumonia: A PERUKI study.

The transition to clinical expert: Enhanced decision making for children aged less than 5years attending the paediatric ED with acute respiratory conditions (2016)
Journal Article
Lyttle, M. D., Bowen, L., Shaw, A., Lyttle, M., & Purdy, S. (2017). The transition to clinical expert: Enhanced decision making for children aged less than 5years attending the paediatric ED with acute respiratory conditions. Emergency Medicine Journal, 34(2), 76-81. https://doi.org/10.1136/emermed-2015-205211

© Published by the BMJ Publishing Group Limited. Background Rates of unplanned paediatric admissions are persistently high. Many admissions are short-stay events, lasting less than 48 hours. Objective This qualitative research explores factors that i... Read More about The transition to clinical expert: Enhanced decision making for children aged less than 5years attending the paediatric ED with acute respiratory conditions.

A qualitative study of the barriers to procedural sedation practices in paediatric emergency medicine in the UK and Ireland (2016)
Journal Article
Lyttle, M. D., McCoy, S., McCoy, S., Lyttle, M., Hartshorn, S., Larkin, P., …O'Sullivan, R. (2016). A qualitative study of the barriers to procedural sedation practices in paediatric emergency medicine in the UK and Ireland. Emergency Medicine Journal, 33(8), 527-532. https://doi.org/10.1136/emermed-2015-205418

© Published by the BMJ Publishing Group Limited. Introduction There is extensive literature on paediatric procedural sedation (PPS) and its clinical applications in emergency departments (EDs). While numerous guidance and policy documents exist from... Read More about A qualitative study of the barriers to procedural sedation practices in paediatric emergency medicine in the UK and Ireland.

Kohler's disease: An unusual cause for a limping child (2016)
Journal Article
Knight, D. M., Lyttle, M. D., James, D. R., Shanley, J., James, D. R., Lyttle, M., …Knight, D. M. A. (2017). Kohler's disease: An unusual cause for a limping child. Archives of Disease in Childhood, 102(1), 109. https://doi.org/10.1136/archdischild-2016-311402

Kohler's disease: an unusual cause for a limping child

New onset strabismus in association with ear pain (2016)
Journal Article
Lyttle, M. D., Ghani, S., Likeman, M., & Lyttle, M. (2017). New onset strabismus in association with ear pain. Archives of Disease in Childhood.education and Practice Edition, 102(5), 267-269. https://doi.org/10.1136/archdischild-2015-310297

Case report of rare diagnosis with peculiar findings

British guideline on the management of asthma: SIGN Clinical Guideline 141, 2014 (2016)
Journal Article
James, D. R., Lyttle, M. D., James, D. R., & Lyttle, M. (2016). British guideline on the management of asthma: SIGN Clinical Guideline 141, 2014. Archives of Disease in Childhood.education and Practice Edition, 101(6), 319-322. https://doi.org/10.1136/archdischild-2015-310145

Overview of national asthma guidance for paediatrics

Fifteen-minute consultation: An evidence-based approach to research without prior consent (deferred consent) in neonatal and paediatric critical care trials (2016)
Journal Article
Lyttle, M. D., Woolfall, K., Frith, L., Dawson, A., Gamble, C., Lyttle, M., & Young, B. (2016). Fifteen-minute consultation: An evidence-based approach to research without prior consent (deferred consent) in neonatal and paediatric critical care trials. Archives of Disease in Childhood.education and Practice Edition, 101(1), 49-53. https://doi.org/10.1136/archdischild-2015-309245

G255(P) Psychological interventions for patients of all ages with mild traumatic brain injury: A systematic review (2016)
Journal Article
Creasey, N., & Lyttle, M. (2016). G255(P) Psychological interventions for patients of all ages with mild traumatic brain injury: A systematic review. Archives of Disease in Childhood, 101(S1), A138-A139. https://doi.org/10.1136/archdischild-2016-310863.246

Introduction Head injury is the commonest injury type in UK children accounting for 350,000 Emergency Department attendances every year. While many of these are trivial a significant proportion have a mild traumatic brain injury (mTBI) which is synon... Read More about G255(P) Psychological interventions for patients of all ages with mild traumatic brain injury: A systematic review.

G213 Handlebar Grip Related Injury Prevention (GRIP) feasibility study: Are exposed metal handlebar ends on children’s bikes and scooters a risk factor for serious injury? (2016)
Journal Article
Neilson, A., Hartshorn, S., & Lyttle, M. (2016). G213 Handlebar Grip Related Injury Prevention (GRIP) feasibility study: Are exposed metal handlebar ends on children’s bikes and scooters a risk factor for serious injury?. Archives of Disease in Childhood, 101(S1), A116-A117. https://doi.org/10.1136/archdischild-2016-310863.204

Aims Handlebar-end impact is a well-recognised cause of major intra-abdominal injury in childhood. Through this feasibility study and the associated main study we aim to reduce the incidence and severity these injuries. Proper understanding of risk f... Read More about G213 Handlebar Grip Related Injury Prevention (GRIP) feasibility study: Are exposed metal handlebar ends on children’s bikes and scooters a risk factor for serious injury?.

Psychosocial Care for Injured Children: Worldwide Survey among Hospital Emergency Department Staff (2015)
Journal Article
Lyttle, M. D., Alisic, E., Hoysted, C., Kassam-Adams, N., Landolt, M. A., Curtis, S., …Babl, F. E. (2016). Psychosocial Care for Injured Children: Worldwide Survey among Hospital Emergency Department Staff. Journal of Pediatrics, 170, 227-233.e6. https://doi.org/10.1016/j.jpeds.2015.10.067

© 2016 Elsevier Inc. Objective To examine emergency department (ED) staff's knowledge of traumatic stress in children, attitudes toward providing psychosocial care, and confidence in doing so, and also to examine differences in these outcomes accordi... Read More about Psychosocial Care for Injured Children: Worldwide Survey among Hospital Emergency Department Staff.

Assessing the impacts of the first year of rotavirus vaccination in the United Kingdom (2015)
Journal Article
Marlow, R., Muir, P., Vipond, B., Lyttle, M., Trotter, C., & Finn, A. (2015). Assessing the impacts of the first year of rotavirus vaccination in the United Kingdom. Eurosurveillance, 20(48), https://doi.org/10.2807/1560-7917.ES.2015.20.48.30077

© 2015, European Centre for Disease Prevention and Control (ECDC). All rights reserved. The United Kingdom (UK) added rotavirus (RV) vaccine (Rotarix GlaxoSmithKline) to the national vaccine schedule in July 2013. During the 2012–2014 rotavirus seaso... Read More about Assessing the impacts of the first year of rotavirus vaccination in the United Kingdom.

Trends in admission and death rates due to paediatric head injury in England, 2000-2011 (2015)
Journal Article
Marlow, R., Mytton, J., Maconochie, I. K., Taylor, H., & Lyttle, M. (2015). Trends in admission and death rates due to paediatric head injury in England, 2000-2011. Archives of Disease in Childhood, 100(12), 1136-1140. https://doi.org/10.1136/archdischild-2015-308615

Background The number of children admitted to hospital is increasing year on year, with very short-stay admissions doubling in the last decade. Childhood head injury accounts for half a million emergency department attendances in the UK every year. T... Read More about Trends in admission and death rates due to paediatric head injury in England, 2000-2011.

Establishing the research priorities of paediatric emergency medicine clinicians in the UK and Ireland (2015)
Journal Article
Hartshorn, S., O'Sullivan, R., Maconochie, I. K., Bevan, C., Cleugh, F., & Lyttle, M. (2015). Establishing the research priorities of paediatric emergency medicine clinicians in the UK and Ireland. Emergency Medicine Journal, 32(11), 864-868. https://doi.org/10.1136/emermed-2014-204484

Objective: Paediatric Emergency Research in the UK and Ireland (PERUKI) is a collaborative clinical studies group established in August 2012. It consists of a network of 43 centres from England, Ireland, Northern Ireland, Scotland and Wales, and aims... Read More about Establishing the research priorities of paediatric emergency medicine clinicians in the UK and Ireland.

Will social media make or break medical conferences? (2015)
Journal Article
Lyttle, M. D., Body, R., Roland, D., May, N., Body, R., Carley, S., & Lyttle, M. (2015). Will social media make or break medical conferences?. British Journal of Hospital Medicine, 76(6), 318-319. https://doi.org/10.12968/hmed.2015.76.6.318

Are you a SCEPTIC? SoCial mEdia Precision and uTility in Conferences (2015)
Journal Article
Lyttle, M. D., Roland, D., May, N., Body, R., Carley, S., & Lyttle, M. (2015). Are you a SCEPTIC? SoCial mEdia Precision and uTility in Conferences. Emergency Medicine Journal, 32(5), 412-413. https://doi.org/10.1136/emermed-2014-204216

We analysed Twitter feeds at an emergency medicine scientific conference to determine the (1) accuracy of disseminated educational messages and the (2) use in providing rapid feedback to speakers. Most speakers were happy for key messages to be tweet... Read More about Are you a SCEPTIC? SoCial mEdia Precision and uTility in Conferences.

Paediatric ED reattendance rates: Comparing nurse practitioners and other clinicians (2015)
Journal Article
Lyttle, M. D., Benger, J. R., Feetham, J. E., Christian, W., Benger, J., Hoskins, R., …Lyttle, M. (2015). Paediatric ED reattendance rates: Comparing nurse practitioners and other clinicians. Emergency Medicine Journal, 32(5), 379-382. https://doi.org/10.1136/emermed-2013-203514

Objective The aim of this project is to establish the unplanned reattendance rate for paediatric emergency nurse practitioners (PENPs) working in a designated paediatric emergency department (PED) while identifying the case mix of patients seen by PE... Read More about Paediatric ED reattendance rates: Comparing nurse practitioners and other clinicians.

The accuracy of existing prehospital triage tools for injured children in England: An analysis using emergency department data (2015)
Journal Article
Ardolino, A., Cheung, C. R., Lawrence, T., Bouamra, O., Lecky, F., Berry, K., …Maconochie, I. (2015). The accuracy of existing prehospital triage tools for injured children in England: An analysis using emergency department data. Emergency Medicine Journal, 32(5), 397-400. https://doi.org/10.1136/emermed-2013-203251

Objective To investigate the performance characteristics in children with moderate and minor injuries of prehospital paediatric triage tools currently in use in England for identifying seriously injured children. Methods Eight prehospital paediatric... Read More about The accuracy of existing prehospital triage tools for injured children in England: An analysis using emergency department data.

Investigation of children with suspected skull fracture - service evaluation at two centres (2015)
Presentation / Conference
Stone, K., & Lyttle, M. (2015, April). Investigation of children with suspected skull fracture - service evaluation at two centres. Paper presented at Royal College of Paediatrics and Child Health Annual Conference 2015, Birmingham, UK

Identifying challenges with paediatric procedural sedation in the ED setting in Ireland and the UK: A Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study (2015)
Presentation / Conference
McCoy, S., Lyttle, M., Hartshorn, S., Larkin, P., Brenner, M., & O'Sullivan, R. (2015, April). Identifying challenges with paediatric procedural sedation in the ED setting in Ireland and the UK: A Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study. Paper presented at Royal College of Paediatrics and Child Health Annual Conference 2015, Birmingham, UK

Emergency department management of children with decompensating inherited metabolic disease (2015)
Presentation / Conference
Gillam, M., Chronopoulou, E., & Lyttle, M. (2015, April). Emergency department management of children with decompensating inherited metabolic disease. Paper presented at Royal College of Paediatrics and Child Health Annual Conference 2015, Birmingham, UK

Psychosocial care for injured children: The views of 2500 emergency department physicians and nurses from around the world (2015)
Presentation / Conference
around the world. Paper presented at Trauma Association of Canada Annual Scientific Meeting, Calgary, Canada

Variation in treatment of acute childhood wheeze in emergency departments of the United Kingdom and Ireland: An international survey of clinician practice (2015)
Journal Article
Lyttle, M. D., Lyttle, M., O'Sullivan, R., Doull, I., Hartshorn, S., Morris, I., …Bolger, T. (2015). Variation in treatment of acute childhood wheeze in emergency departments of the United Kingdom and Ireland: An international survey of clinician practice. Archives of Disease in Childhood, 100(2), 121-125. https://doi.org/10.1136/archdischild-2014-306591

© 2015, BMJ Publishing Group. All rights reserved. Objective: National clinical guidelines for childhood wheeze exist, yet despite being one of the most common reasons for childhood emergency department (ED) attendance, signi ficant variation in prac... Read More about Variation in treatment of acute childhood wheeze in emergency departments of the United Kingdom and Ireland: An international survey of clinician practice.

Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland? (2015)
Journal Article
Powell, C. V., Lyttle, M. D., Morris, I., Lyttle, M., O'Sullivan, R., Sargant, N., …Powell, C. (2015). Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland?. Thorax, 70(1), 88-91. https://doi.org/10.1136/thoraxjnl-2014-206041

During a prospective 10-week assessment period, 3238 children aged 1-16 years presented with acute wheeze to Paediatric Emergency Research in the UK and Ireland centres. 110 (3.3%) received intravenous bronchodilators. Intravenous magnesium sulfate (... Read More about Which intravenous bronchodilators are being administered to children presenting with acute severe wheeze in the UK and Ireland?.

A prospective observational study to assess the diagnostic accuracy of clinical decision rules for children presenting to emergency departments after head injuries (protocol): The Australasian Paediatric Head Injury Rules Study (APHIRST) (2014)
Journal Article
Oakley, E., Williams, A., Crowe, L., Jachno, K., Donath, S., Neutze, J., …Furyk, J. (2014). A prospective observational study to assess the diagnostic accuracy of clinical decision rules for children presenting to emergency departments after head injuries (protocol): The Australasian Paediatric Head Injury Rules Study (APHIRST). BMC Pediatrics, 14(1), 148. https://doi.org/10.1186/1471-2431-14-148

Background: Head injuries in children are responsible for a large number of emergency department visits. Failure to identify a clinically significant intracranial injury in a timely fashion may result in long term neurodisability and death. Whilst cr... Read More about A prospective observational study to assess the diagnostic accuracy of clinical decision rules for children presenting to emergency departments after head injuries (protocol): The Australasian Paediatric Head Injury Rules Study (APHIRST).

G12 what are the research priorities of paediatric emergency medicine clinicians in the United Kingdom and Ireland? An international survey (2014)
Journal Article
Hartshorn, S., Bevan, C., Cleugh, F., Lyttle, M., Maconochie, I. K., & O'Sullivan, R. (2014). G12 what are the research priorities of paediatric emergency medicine clinicians in the United Kingdom and Ireland? An international survey. Archives of Disease in Childhood, 99(Supp1), A5-A6. https://doi.org/10.1136/archdischild-2014-306237.12

What intravenous treatment is currently being administered for acute severe wheeze in childhood in emergency departments around the UK and Ireland? (2014)
Journal Article
Morris, I., Lyttle, M., Doull, I., O'Sullivan, R., & Powell, C. (2014). What intravenous treatment is currently being administered for acute severe wheeze in childhood in emergency departments around the UK and Ireland?. Archives of Disease in Childhood, 99(S-1), A39-A40. https://doi.org/10.1136/archdischild-2014-306237.92

Clinician variation in treating childhood wheeze in emergency departments of the United Kingdom and Ireland: An international survey (2014)
Journal Article
Lyttle, M., O'Sullivan, R., Doull, I., Morris, I., & Powell, C. (2014). Clinician variation in treating childhood wheeze in emergency departments of the United Kingdom and Ireland: An international survey. Archives of Disease in Childhood, 99(S-1), A2-A2. https://doi.org/10.1136/archdischild-2014-306237.3

Early management of head injury: Summary of updated NICE guidance (2014)
Journal Article
Lecky, F., Pollit, V., Hodgkinson, S., Pollitt, V., & Sharpin, C. (2014). Early management of head injury: Summary of updated NICE guidance. BMJ, 348, 1-7. https://doi.org/10.1136/bmj.g104

Head injury is the commonest cause of death and disability in people aged 1-40 years in the UK. Each year, 1.4 million people attend emergency departments in England and Wales with a recent head injury. The National Institute for Health and Care Exce... Read More about Early management of head injury: Summary of updated NICE guidance.

From cradle to adolescence: The development of Research in European Pediatric Emergency Medicine (2014)
Journal Article
Lyttle, M. D., Mintegi, S., Lyttle, M., MacOnochie, I. K., Benito, J., Gervaix, A., …Waisman, Y. (2014). From cradle to adolescence: The development of Research in European Pediatric Emergency Medicine. European Journal of Emergency Medicine, 21(1), 24-29. https://doi.org/10.1097/MEJ.0b013e328364d807

Pediatric emergency medicine (PEM) has been developing rapidly but heterogeneously in many European countries in recent years, and many national PEM societies have been founded to improve the quality of care of ill and injured children and adolescent... Read More about From cradle to adolescence: The development of Research in European Pediatric Emergency Medicine.

When do children get burnt? (2014)
Journal Article
Lyttle, M. D., Verey, F., Lyttle, M., Lawson, Z., Greenwood, R., & Young, A. (2014). When do children get burnt?. Burns, 40(7), 1322-1328. https://doi.org/10.1016/j.burns.2014.01.010

© 2014 Elsevier Ltd and ISBI. All rights reserved. Burns are a cause of more than 5000 paediatric hospital admissions per year in England and Wales. Injury prevention and service provision may be better planned with knowledge of burn timing. Prospect... Read More about When do children get burnt?.

Pediatric Emergency Research in the UK and Ireland (PERUKI): Developing a collaborative for multicentre research (2014)
Journal Article
Lyttle, M. D., Maconochie, I., Lyttle, M., O'Sullivan, R., Hartshorn, S., Bevan, C., …Maconochie, I. K. (2014). Pediatric Emergency Research in the UK and Ireland (PERUKI): Developing a collaborative for multicentre research. Archives of Disease in Childhood, 99(6), 602-603. https://doi.org/10.1136/archdischild-2013-304998

Trends in admission and death rates due to paediatric head injury in England and Wales 2000-2012 (2014)
Journal Article
Marlow, R., & Lyttle, M. (2014). Trends in admission and death rates due to paediatric head injury in England and Wales 2000-2012. Archives of Disease in Childhood, 99(S-1), A6-A6. https://doi.org/10.1136/archdischild-2014-306237.13

The transition to expert: A qualitative study exploring clinical decision making for children under five attending the emergency department with minor respiratory conditions (2014)
Journal Article
Bowen, L., Purdy, S., Lyttle, M., & Heawood, A. (2014). The transition to expert: A qualitative study exploring clinical decision making for children under five attending the emergency department with minor respiratory conditions. Emergency Medicine Journal, 31(9), 791-791. https://doi.org/10.1136/emermed-2014-204221.31

Applicability of the CATCH, CHALICE and PECARN paediatric head injury clinical decision rules: Pilot data from a single Australian centre (2013)
Journal Article
Lyttle, M. D., Lyttle, M., Cheek, J. A., Blackburn, C., Oakley, E., Ward, B., …Babl, F. E. (2013). Applicability of the CATCH, CHALICE and PECARN paediatric head injury clinical decision rules: Pilot data from a single Australian centre. Emergency Medicine Journal, 30(10), 790-794. https://doi.org/10.1136/emermed-2012-201887

Background Clinical decision rules (CDRs) for paediatric head injury (HI) exist to identify children at risk of traumatic brain injury. Those of the highest quality are the Canadian assessment of tomography for childhood head injury (CATCH), Children... Read More about Applicability of the CATCH, CHALICE and PECARN paediatric head injury clinical decision rules: Pilot data from a single Australian centre.

Predictors of severe H1N1 infection in children presenting within Pediatric Emergency Research Networks (PERN): Retrospective case-control study (2013)
Journal Article
Klassen, T. P., Kuppermann, N., Newton, A. S., Fitzpatrick, E., Black, K. J., Valerio, P., …Macias, C. G. (2013). Predictors of severe H1N1 infection in children presenting within Pediatric Emergency Research Networks (PERN): Retrospective case-control study. BMJ, 347(7921), https://doi.org/10.1136/bmj.f4836

Objective To identify historical and clinical findings at emergency department presentation associated with severe H1N1 outcome in children presenting with influenza-like illness. Design Multicentre retrospective case-control study. Setting 79 emerge... Read More about Predictors of severe H1N1 infection in children presenting within Pediatric Emergency Research Networks (PERN): Retrospective case-control study.

The accuracy of existing prehospital triage tools for injured children in England - An analysis using trauma registry data (2013)
Journal Article
Lyttle, M. D., Cheung, R., Ardolino, A., Lawrence, T., Bouamra, O., Lecky, F., …Maconochie, I. K. (2013). The accuracy of existing prehospital triage tools for injured children in England - An analysis using trauma registry data. Emergency Medicine Journal, 30(6), 476-479. https://doi.org/10.1136/emermed-2012-201324

Objectives: To investigate the performance characteristics of prehospital paediatric triage tools for identifying seriously injured children in England. Design: Eight prehospital paediatric triage tools were identified by literature review and by sur... Read More about The accuracy of existing prehospital triage tools for injured children in England - An analysis using trauma registry data.

The child with decreased consciousness (2013)
Book Chapter
Lyttle, M. (2013). The child with decreased consciousness. In R. Skone (Ed.), Managing the Critically Ill Child: A Guide for Anaesthetists and Emergency Physicians. Cambridge University Press

Survey of the use of therapeutic hypothermia after cardiac arrest in UK paediatric emergency departments (2013)
Journal Article
Duncan, H. P., Lyttle, M. D., Scholefield, B. R., Scholefield, B. R., Lyttle, M., Berry, K., …Morris, K. P. (2013). Survey of the use of therapeutic hypothermia after cardiac arrest in UK paediatric emergency departments. Emergency Medicine Journal, 30(1), 24-27. https://doi.org/10.1136/emermed-2011-200348

Objectives: To ascertain current use of therapeutic hypothermia (TH) after paediatric cardiac arrest in UK emergency departments (EDs), and views on participating in a UK randomised controlled trial (RCT) incorporating early induction of TH in ED. De... Read More about Survey of the use of therapeutic hypothermia after cardiac arrest in UK paediatric emergency departments.

Using existing paediatric pre-hospital trauma triage tools to identify children with severe traumatic brain injury: An analysis of national trauma registry data (2013)
Journal Article
Lyttle, M., Ardolino, A., Berry, K., Bouamra, O., Cheung, R., Lawrence, T., …Maconochie, I. K. (2013). Using existing paediatric pre-hospital trauma triage tools to identify children with severe traumatic brain injury: An analysis of national trauma registry data. Emergency Medicine Journal, 30(10), 879-879. https://doi.org/10.1136/emermed-2013-203113.33

Comparing CATCH, CHALICE and PECARN clinical decision rules for paediatric head injuries (2012)
Journal Article
Lyttle, M., Crowe, L., Crowe, E., Dunning, J., & Babl, F. E. (2012). Comparing CATCH, CHALICE and PECARN clinical decision rules for paediatric head injuries. Emergency Medicine Journal, 29(10), 785-794. https://doi.org/10.1136/emermed-2011-200225

Many children present to emergency departments following head injury (HI), with a small number at risk of avoidable poor outcome. Difficulty identifying such children, coupled with increased availability of cranial CT, has led to variation in practic... Read More about Comparing CATCH, CHALICE and PECARN clinical decision rules for paediatric head injuries.

Comparing CATCH, CHALICE and PECARN clinical decision rules for paediatric head injuries (2012)
Journal Article
Lyttle, M. D., Lyttle, M., Crowe, L., Oakley, E., Dunning, J., & Babl, F. E. (2012). Comparing CATCH, CHALICE and PECARN clinical decision rules for paediatric head injuries. Emergency Medicine Journal, 29(10), 785-794. https://doi.org/10.1136/emermed-2011-200225

Many children present to emergency departments following head injury (HI), with a small number at risk of avoidable poor outcome. Difficulty identifying such children, coupled with increased availability of cranial CT, has led to variation in practic... Read More about Comparing CATCH, CHALICE and PECARN clinical decision rules for paediatric head injuries.

Transdermal fentanyl in deliberate overdose in pediatrics (2012)
Journal Article
Lyttle, M., Verma, S., & Isaac, R. (2012). Transdermal fentanyl in deliberate overdose in pediatrics. Pediatric Emergency Care, 28(5), 463-464. https://doi.org/10.1097/PEC.0b013e31825358b4

The use of the fentanyl skin patch to provide pain relief in chronic pain conditions and oncology in adult practice has been common for several years, and an increase in use is now being seen in pediatric practice. Its use in drug misuse and suicide... Read More about Transdermal fentanyl in deliberate overdose in pediatrics.

A Comprehensive Framework for Determining the Cost of an Emergency Medical Services System (2006)
Journal Article
Lerner, E. B., Nichol, G., Spaite, D. W., Garrison, H. G., Maio, R. F., Lyttle, M. D., & Cheek, J. A. (2007). A Comprehensive Framework for Determining the Cost of an Emergency Medical Services System. Annals of Emergency Medicine, 49(3), 304-313. https://doi.org/10.1016/j.annemergmed.2006.09.019

To determine the cost of an emergency medical services (EMS) system, researchers, policymakers, and EMS providers need a framework with which to identify the components of the system that must be included in any cost calculations. Such a framework wi... Read More about A Comprehensive Framework for Determining the Cost of an Emergency Medical Services System.