All Outputs (20)

Intraputamenal cerebral dopamine neurotrophic factor in Parkinson's disease: A randomized, double‐blind, multicenter phase 1 trial (2023)
Journal Article

Background: Cerebral dopamine neurotrophic factor (CDNF) is an unconventional neurotrophic factor that protects dopamine neurons and improves motor function in animal models of Parkinson's disease (PD). Objective: The primary objectives of this study... Read More about Intraputamenal cerebral dopamine neurotrophic factor in Parkinson's disease: A randomized, double‐blind, multicenter phase 1 trial.

The Bristol Bladder Trial: Five year outcomes in patients treated with neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder (2023)
Presentation / Conference Contribution

Background: Neoadjuvant cisplatin-based combination chemotherapy (NAC) improves survival in muscle invasive bladder cancer (MIBC). However, response rates and survival remain suboptimal. We sought to evaluate the efficacy of cabazitaxel with cisplati... Read More about The Bristol Bladder Trial: Five year outcomes in patients treated with neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder.

A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder (2021)
Journal Article

Introduction: Neoadjuvant cisplatin-based combination chemotherapy improves survival in muscle-invasive bladder cancer. However, response rates and survival remain suboptimal. We evaluated the efficacy, safety, and tolerability of cisplatin plus caba... Read More about A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder.

Intramuscular oxytocin versus Syntometrine® versus carbetocin for prevention of primary postpartum haemorrhage after vaginal birth: a randomised double-blinded clinical trial of effectiveness, side effects and quality of life (2020)
Journal Article

Objective: To compare intramuscular oxytocin, Syntometrine® and carbetocin for prevention of postpartum haemorrhage after vaginal birth. Design: Randomised double-blinded clinical trial. Setting: Six hospitals in England. Population: A total of 5929... Read More about Intramuscular oxytocin versus Syntometrine® versus carbetocin for prevention of primary postpartum haemorrhage after vaginal birth: a randomised double-blinded clinical trial of effectiveness, side effects and quality of life.

Pathological response rates and quality of life outcomes of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle-invasive transitional cell carcinoma of the urinary bladder (2020)
Journal Article

Use of procalcitonin as a biomarker for sepsis in moderate to major paediatric burns (2018)
Journal Article

Introduction: Accurate and early detection of sepsis poses a significant challenge in burn populations. Our objective was to assess whether procalcitonin is a marker of blood culture positive sepsis in moderate to severe paediatric burns. Methods: We... Read More about Use of procalcitonin as a biomarker for sepsis in moderate to major paediatric burns.

The Bristol Bladder trial: A single-arm phase II trial of cisplatin and cabazitaxel for muscle invasive transitional cell carcinoma of the urinary bladder prior to radical cystectomy (2018)
Journal Article

Adolescent self-harm in the community: An update on prevalence using a self-report survey of adolescents aged 13-18 in England (2017)
Journal Article

© The Author 2016. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. Background To establish an estimate of prevalence in a nationally representative sample of community adolescents. To examine associati... Read More about Adolescent self-harm in the community: An update on prevalence using a self-report survey of adolescents aged 13-18 in England.

The safety of general anaesthesia in paediatric patients undergoing the application of Biobrane® for small scalds (2015)
Journal Article

© 2015 Elsevier Ltd and ISBI. All rights reserved. Background Each year more than 5000 children present to English and Welsh hospitals for the management of scalds; 60% of these are small scalds of less than 10% body surface area. There are no agreed... Read More about The safety of general anaesthesia in paediatric patients undergoing the application of Biobrane® for small scalds.

Procalcitonin – a biomarker for sepsis in moderate to major paediatric burns (2015)
Presentation / Conference Contribution

A panel-based prevalence study of self-reported self-harm in adolescents aged 13-18 in England (2014)
Presentation / Conference Contribution

Personal birth preferences and actual mode of delivery outcomes of obstetricians and gynaecologists in South West England; With comparison to regional and national birth statistics (2014)
Journal Article

© 2014 Elsevier Ireland Ltd. All rights reserved. Objective: To determine personal birth preferences of obstetricians in various clinical scenarios, in particular elective caesarean section for maternal request. To determine actual rates of modes of... Read More about Personal birth preferences and actual mode of delivery outcomes of obstetricians and gynaecologists in South West England; With comparison to regional and national birth statistics.

Use Of The Warwick-Edinburgh mental wellbeing scale in a survey study of self-reported self-harm amongst 13 – 18 year olds across England (2014)
Presentation / Conference Contribution

Food sustainability education as a route to healthier eating: Evaluation of a multi-component school programme in English primary schools (2012)
Journal Article

Promising approaches to the promotion of healthier eating among children in primary school settings include the opportunity to practise practical cooking and growing, promoting the take up of healthier school meals and nutritional education. However,... Read More about Food sustainability education as a route to healthier eating: Evaluation of a multi-component school programme in English primary schools.

Engaging secondary school students in food-related citizenship: Achievements and challenges of a multi-component programme (2012)
Journal Article

© 2012 by the authors; licensee MDPI, Basel, Switzerland. Global food security and sustainability, animal welfare, dietary health, and socially just relations of food production have become prominent societal issues. They are of particular concern fo... Read More about Engaging secondary school students in food-related citizenship: Achievements and challenges of a multi-component programme.

Food for life partnership evaluation: summary report (2011)
Report

Summary report of the Food for Life Partnership evaluation conducted by UWE,Bristol and Cardiff University. May 2011

Food for life partnership evaluation: Full report (2011)
Report

Full report on the evaluation of the Food for Life Partnership programme. May 2011

Garden enhanced education: Report on the growing skills programme in Food for Life partnership schools (2010)
Report

Research shows that a diet rich in fruit and vegetables is associated with a decreased risk of many chronic diseases and can form part of an effective weight management strategy. However, only one in five children consume the recommended daily intake... Read More about Garden enhanced education: Report on the growing skills programme in Food for Life partnership schools.

Selecting the best population: A decision theoretic approach: The case of Pareto distribution (1985)
Report

The main ideas in selecting the best populations meeting some prescribed optimality criterion have been mooted originally by Bechchofer and Gupta and the subject has gone from strength to strength by several contributions by several statisticians ove... Read More about Selecting the best population: A decision theoretic approach: The case of Pareto distribution.

On the selection of the best gamma population. Determination of minimax sample sizes
Report

Selecting the best Gamma population from a given set of Gamma populations is treated from a decision theoretic point of view. Cost of sampling and penalties for wrong decision play a role in the determination of optimum common sample sizes. Minimax s... Read More about On the selection of the best gamma population. Determination of minimax sample sizes.