Shedding smart light on the effectiveness of chemotherapy: using Raman spectroscopy and machine learning to differentiate the effects of Cytarabine toxicity and crosstalk of leukaemic and bone marrow stromal cells

Gynn, Liana; Lamb-Riddell, Kathryn; Cox, Timothy; Hansen, Mark; Conway, Myra; May, Jennifer

All Outputs (6)

Homes under the microscope: Results from a pilot community science approach to measure airborne microfibres in the home (2025)
Journal Article

Non-natural airborne microfibres are an emerging concern in indoor air pollution, yet relatively little is known about their sources or concentrations. This is particularly relevant in home environments, where individuals spend significant amounts of... Read More about Homes under the microscope: Results from a pilot community science approach to measure airborne microfibres in the home.

Co-creation in citizen science: Sharing learnings and good practice from an indoor, airborne microplastics project (2025)
Journal Article

HOMEs was a citizen science exploratory project, aimed at investigating the presence of airborne microplastics in people's homes. Participants placed passive samplers in their homes, using low-cost microscopes to see and take pictures of their sample... Read More about Co-creation in citizen science: Sharing learnings and good practice from an indoor, airborne microplastics project.

Embedding citizens within airborne microplastic and microfibre research (2023)
Journal Article

Microplastics are ubiquitous in our environment but their presence in air is less well understood. Homes are likely a key source of airborne microplastics and microfibres to the environment owing to the frequent use and storage of plastics and textil... Read More about Embedding citizens within airborne microplastic and microfibre research.

Airborne Microplastics measurement: Putting people at the heart of the science (2023)
Presentation / Conference Contribution

Modelling a dynamic magneto-agglutination bioassay (2022)
Journal Article

The process of developing an end-to-end model of a magneto-immunoassay is described, simulating the agglutination effect due to the specific binding of bacteria to paramagnetic particles. After establishing the properties of the dose-specific aggluti... Read More about Modelling a dynamic magneto-agglutination bioassay.

Shedding smart light on the effectiveness of chemotherapy: using Raman spectroscopy and machine learning to differentiate the effects of Cytarabine toxicity and crosstalk of leukaemic and bone marrow stromal cells (2021)
Presentation / Conference Contribution

Mesenchymal stromal cells (MSC) protect leukaemic cells from drug-induced toxicity within the bone marrow niche, with increasing evidence of leukaemic impact on supportive stroma. The nucleoside analogue, cytarabine (ara-C), is a front-line agent for... Read More about Shedding smart light on the effectiveness of chemotherapy: using Raman spectroscopy and machine learning to differentiate the effects of Cytarabine toxicity and crosstalk of leukaemic and bone marrow stromal cells.