Mathematical analysis on urine flow traces for non-invasive diagnosis of Detrusor underactivity in men

Li, Rui; Gammie, Andrew; Zhu, Quanmin; Nibouche, Mokhtar

Abstract

Detrusor underactivity (DU) is still largely under researched and can only be diagnosed by invasive pressure flow studies (PFS). Theoretically, the flow shape of DU is different from bladder outlet obstruction (BOO), but in practice PFS is the only gold standard for diagnosing DU. It is suggested that detrusor muscle contraction and abdominal squeezing act in total different frequencies, 0.1Hz and 1Hz respectively, which could be an indicator for differentiating DU and BOO. However, this hypothesis has not been quantitatively validated. Therefore, continuing last year’s research, we have conducted a novel study on validating frequencies of abdominal and detrusor muscle activity as reflected in urine flow, and propose a potential indicator for diagnosing DU.

• Journal Article Type: Article
• Acceptance Date: May 1, 2017
• Online Publication Date: Jul 31, 2017
• Publication Date: Jul 26, 2017
• Deposit Date: Dec 11, 2017
• Publicly Available Date: Jul 31, 2018
• Journal: Neurourology and Urodynamics
• Print ISSN: 0733-2467
• Electronic ISSN: 1520-6777
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 36
• Issue: S3
• Pages: 87-88
• Keywords: detrusor underactivity, non-invasive, bladder outlet obstruction
• Public URL: https://uwe-repository.worktribe.com/output/883915
• Publisher URL: http://dx.doi.org/10.1002/nau.23386
• Additional Information: Additional Information : This is the peer reviewed version of the following article: [FULL CITE], which has been published in final form at http://dx.doi.org/10.1002/nau.23386. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
• Contract Date: Dec 11, 2017