Priorities for nutrition research in pediatric critical care

Tume, Lyvonne N; Valla, Frederic V; Floh, Alejandro; Goday, Praveen; Jotterand Chaparro, Corrine; Larsen, Bodil; Lee, Jan Hau; Moreno, Yara; Patham, Nazima; Verbruggen, Sascha; Mehta, Nilesh

Abstract

Background: Widespread variation exists in pediatric critical care nutrition practices, largely because of the scarcity of evidence to guide best practice recommendations.

Objective: The objective of this paper was to develop a list of topics to be prioritized for nutrition research in pediatric critical care in the next 10 years.

Methods: A modified 3-round Delphi process was undertaken by a newly established multidisciplinary group comprising 11 international researchers in the field of pediatric critical care nutrition. Items were ranked on a 5-point Likert scale.

Results: Forty-five research topics (with a mean priority score >3(0-5) were identified within the following 10 domains: the pathophysiology and impact of malnutrition in critical illness; nutrition assessment: nutrition risk assessment and biomarkers; accurate assessment of energy requirements in all phases of critical illness; the role of protein intake; the role of pharmaco-nutrition; effective and safe delivery of enteral nutrition; enteral feeding intolerance: assessment and management; the role of parenteral nutrition; the impact of nutrition status and nutrition therapies on long-term patient outcomes; and nutrition therapies for specific populations. Ten top research topics (that received a mean score >4(0-5) were identified as the highest priority for research.

Conclusions: This paper has identified important consensus-derived priorities for clinical research in pediatric critical care nutrition. Future studies should determine topics that are a priority for patients and parents. Research funding should target these priority areas and promote an international collaborative approach to research in this field, with a focus on improving relevant patient outcomes.

• Journal Article Type: Article
• Acceptance Date: Dec 3, 2018
• Online Publication Date: Dec 26, 2018
• Publication Date: Sep 1, 2019
• Deposit Date: Dec 10, 2018
• Publicly Available Date: Dec 27, 2019
• Journal: Journal of Parenteral and Enteral Nutrition
• Print ISSN: 0148-6071
• Electronic ISSN: 1941-2444
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 43
• Issue: 7
• Pages: 853-862
• DOI: https://doi.org/10.1002/jpen.1498
• Keywords: research priorities, nutrition, child, critically ill
• Public URL: https://uwe-repository.worktribe.com/output/855641
• Publisher URL: https://doi.org/10.1002/jpen.1498
• Additional Information: Additional Information : This is the peer reviewed version of the following article: Tume, L. N. , Valla, F. V. , Floh, A. , Goday, P. , Jotterand Chaparro, C. , Larsen, B. , Lee, J. H. , Moreno, Y. , Patham, N. , Verbruggen, S. and Mehta, N. (2018) Priorities for nutrition research in pediatric critical care. Journal of Parenteral and Enteral Nutrition. ISSN 0148-6071, which has been published in final form at https://doi.org/10.1002/jpen.1498. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
• Contract Date: Dec 10, 2018