Outputs (38)

HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings (2023)
Journal Article

Disinfection is a mainstay of infection prevention, the importance of which was highlighted throughout the SARS-CoV-2 pandemic. There is frequent misuse of terminology surrounding chlorine solutions in the literature. This leads not only to confusion... Read More about HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings.

An N-cyanoamide derivative of lithocholic acid co-operates with lysophosphatidic acid to promote human osteoblast (MG63) differentiation (2023)
Journal Article

Less-calcaemic vitamin D receptor (VDR) agonists have the potential to promote osteoblast maturation in a bone regenerative setting. The emergence of lithocholic acid (LCA) as a bona fide VDR agonist holds promise as an adjunct for arthroplasty follo... Read More about An N-cyanoamide derivative of lithocholic acid co-operates with lysophosphatidic acid to promote human osteoblast (MG63) differentiation.

Nanotechnology improves disease resistance in plants for food security: Applications and challenges (2023)
Journal Article

Green synthesis of nano-fertilizers is emerging as a potential strategy and could play a crucial role in disease mitigation, diagnosis, or suppression. Different nanoscale devices (nanoparticles, NPs), biosensors, nano-diagnostic kits, nanofabricatio... Read More about Nanotechnology improves disease resistance in plants for food security: Applications and challenges.

Are protein cavities and pockets commonly used by redox active signalling molecules? (2023)
Journal Article

It has been well known for a long time that inert gases, such as xenon (Xe), have significant biological effects. As these atoms are extremely unlikely to partake in direct chemical reactions with biomolecules such as proteins, lipids, and nucleic ac... Read More about Are protein cavities and pockets commonly used by redox active signalling molecules?.

Sex estimation from virtual models: Exploring the potential of stereolithic (STL) 3D crania models for morphoscopic trait scoring (2023)
Journal Article

Modern computed tomography (CT) databases are becoming an accepted resource for the practice and development of identification methods in forensic anthropology. However, the utility of 3D models created using free and open-source visualization softwa... Read More about Sex estimation from virtual models: Exploring the potential of stereolithic (STL) 3D crania models for morphoscopic trait scoring.

Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids (2023)
Journal Article

This paper describes, for the first time, the development of a novel trilinolein biosensor based on the immobilisation of lipase and lipoxygenase (LOX) onto a cobalt phthalocyanine screen-printed carbon electrode (CoPC-SPCE) in conjunction with amper... Read More about Development of a novel dual-enzyme screen-printed amperometric biosensor for the analysis of esterified fatty acids.

Genotoxicity of cytokines at chemotherapy-induced 'storm' concentrations in a model of the human bone marrow (2023)
Journal Article

Donor cell leukaemia (DCL) is a complication of haematopoietic stem cell transplantation where donated cells become malignant within the patient's bone marrow. As DCL predominates as acute myeloid leukaemia, we hypothesized that the cytokine storm fo... Read More about Genotoxicity of cytokines at chemotherapy-induced 'storm' concentrations in a model of the human bone marrow.

Why Elephants Cry: How Observing Unusual Animal Behaviours Can Predict the Weather (and other Environmental Phenomena) (2023)
Book

Why Elephants Cry is a fascinating frolic through the literature and evidence surrounding the use of unusual behavior of animals to measure and predict the environment. The role of animals, from the smallest ant to the biggest elephant, as predictors... Read More about Why Elephants Cry: How Observing Unusual Animal Behaviours Can Predict the Weather (and other Environmental Phenomena).

New boundaries: Redefining the geographical range of a threatened fish through environmental DNA survey (2023)
Journal Article

Accurate data on the distribution and population status of threatened fish species are fundamental for effective conservation planning and management. In this work, in order to reassess the distribution of the globally threatened Evia barbel, Barbus... Read More about New boundaries: Redefining the geographical range of a threatened fish through environmental DNA survey.

Metabolic reprogramming and the role of the BCAT protein - implications for type 2 diabetes and Alzheimer's disease (2023)
Thesis

Introduction: Oxidative stress and impaired homeostasis are key features of type 2 diabetes mellitus, which is comorbid with Alzheimer’s disease. Dysregulation of the branched-chain aminotransferase protein, which is overexpressed in AD, is suggested... Read More about Metabolic reprogramming and the role of the BCAT protein - implications for type 2 diabetes and Alzheimer's disease.

Development of an antimicrobial lipid coating to prevent infections in uncemented joint replacements (2023)
Presentation / Conference Contribution

Preventing infections in joint replacements is a major ongoing challenge, with limited effective clinical technologies currently available for uncemented knee and hip prostheses. This research aims to develop a coating for titanium implants, consisti... Read More about Development of an antimicrobial lipid coating to prevent infections in uncemented joint replacements.

Human stem cell-derived ventral midbrain astrocytes exhibit a region-specific secretory profile (2023)
Journal Article

This scientific commentary refers to ‘Human stem cell-derived astrocytes exhibit region-specific heterogeneity in their secretory profiles’, by Clarke et al. (https://doi.org/10.1093/brain/awaa258) in Brain.

Promoting dietary changes for achieving health and sustainability targets (2023)
Journal Article

Globally, about 21–37% of total greenhouse gas (GHG) emissions are attributable to food systems. Dietary-related non-communicable diseases have increased significantly from 1990–2019 at a global scale. To achieve carbon emissions targets, increase re... Read More about Promoting dietary changes for achieving health and sustainability targets.

The on/off history of hydrogen in medicine: Will the interest persist this time around? (2023)
Journal Article

Over 2000 publications including more than 100 human studies seem to indicate that humans have only recently benefited from or known about the medical effects of H2 within the past 15 years. However, we have unknowingly benefited from H2 since the da... Read More about The on/off history of hydrogen in medicine: Will the interest persist this time around?.

The early history of hydrogen and other gases in respiration and biological systems: Revisiting Beddoes, Cavallo, and Davy (2023)
Journal Article

In 2007 a paper in Nature Medicine sparked a new wave of interest in the use of molecular hydrogen (H2) for medical treatments. Since then there has been a flurry of papers looking at a range of medical aspects, from neurodegenerative disease to spor... Read More about The early history of hydrogen and other gases in respiration and biological systems: Revisiting Beddoes, Cavallo, and Davy.

Slow violence and river abuse: The hidden effect of land use on water quality (2023)
Exhibition / Performance

Researchers from HAS, Dr Gillian Clayton and Professor Darren Reynolds (HAS) and Researchers from ACE Niamh Fahy and Associate Professor Sarah Bodman have been collaborating on a project in Somerset, UK, from which Niamh is using data and samples col... Read More about Slow violence and river abuse: The hidden effect of land use on water quality.

Description of Dryocola gen. nov. and two novel species, Dryocola boscaweniae sp. nov. and Dryocola clanedunensis sp. nov. isolated from the rhizosphere of native British oaks (2023)
Journal Article

While investigating the role of the rhizosphere in the development of Acute Oak Decline, bacterial strains belonging to the family Enterobacteriaceae were isolated from rhizosphere soil following enrichment for the Enterobacterales. Partial sequencin... Read More about Description of Dryocola gen. nov. and two novel species, Dryocola boscaweniae sp. nov. and Dryocola clanedunensis sp. nov. isolated from the rhizosphere of native British oaks.

Variations in bacteriological and physicochemical water quality characteristics of Asata River, Enugu, Nigeria (2023)
Journal Article

Background and Objective: Globally, river water remains an important source of water for drinking, domestic and other uses. This study aimed to assess the bacteriological and physicochemical properties of Asata River water. Materials and Methods: A... Read More about Variations in bacteriological and physicochemical water quality characteristics of Asata River, Enugu, Nigeria.