Skip to main content

Research Repository

Advanced Search

Outputs (893)

The molecular epidemiology of ampC-mediated resistance in Escherichia coli: A study of clinical strains isolated from the South West region (2016)
Thesis

Escherichia coli is a common human pathogen, capable of causing a wide range of infections. Some strains produce AmpC beta-lactamase, an enzyme able to affect the action of antibiotics. These strains are often resistant to cephalosporin antibiotics,... Read More about The molecular epidemiology of ampC-mediated resistance in Escherichia coli: A study of clinical strains isolated from the South West region.

Mitigating the impact of Bats in historic churches: The response of Natterer's Bats Myotis nattereri to artificial roosts and deterrence (2016)
Journal Article

© 2016 Zeale et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cred... Read More about Mitigating the impact of Bats in historic churches: The response of Natterer's Bats Myotis nattereri to artificial roosts and deterrence.

Development of a voltammetric assay, using screen-printed electrodes, for clonazepam and its application to beverage and serum samples (2015)
Journal Article

© 2015 Elsevier B.V. All rights reserved. This paper describes the development of an electrochemical assay based on screen-printed carbon sensors for the determination of clonazepam in serum and in wine. The cyclic voltammetric behaviour of the drug... Read More about Development of a voltammetric assay, using screen-printed electrodes, for clonazepam and its application to beverage and serum samples.

Development of generic methods for the analysis and purification of polar compounds by high performance liquid chromatography (2016)
Thesis

Generic methods were developed using different columns for analysis and purification of hydrophilic compounds by hydrophilic interaction chromatography (HILIC). Mobile phases were investigated in detail, and across each column chemistry tested (BEH A... Read More about Development of generic methods for the analysis and purification of polar compounds by high performance liquid chromatography.

The determination of nicotine in third-hand smoke by liquid chromatography with electrochemical detection and its application for the assessment of contaminated communal areas (2017)
Presentation / Conference Contribution

The term third-hand smoke (THS) can be defined as the contamination of surfaces by tobacco smoke. This can remain for extended periods of time and undergo further chemical reactions to produce further pollutants which can be re-suspended in dust or... Read More about The determination of nicotine in third-hand smoke by liquid chromatography with electrochemical detection and its application for the assessment of contaminated communal areas.

Measurement of total cholesterol using an enzyme sensor based on a printed hydrogen peroxide electrocatalyst (2016)
Journal Article

© 2016 The Royal Society of Chemistry. Cholesterol is a major modifiable risk factor in cardiovascular disease and can be effectively managed by a combination of medication and monitoring. There continues to be a need for new point-of-care diagnostic... Read More about Measurement of total cholesterol using an enzyme sensor based on a printed hydrogen peroxide electrocatalyst.

Recent advances in the fabrication and application of screen-printed electrochemical (bio)sensors based on carbon materials for biomedical, agri-food and environmental analyses (2016)
Journal Article

This review describes recent advances in the fabrication of electrochemical (bio)sensors based on screen-printing technology involving carbon materials and their application in biomedical, agri-food and environmental analyses. It will focus on the va... Read More about Recent advances in the fabrication and application of screen-printed electrochemical (bio)sensors based on carbon materials for biomedical, agri-food and environmental analyses.

High-resolution melt and morphological analyses of mealybugs (Hemiptera: Pseudococcidae) from cacao: Tools for the control of Cacao swollen shoot virus spread (2015)
Journal Article

© 2015 Society of Chemical Industry. BACKGROUND: Mealybugs (Hemiptera: Coccoidea: Pseudococcidae) are key vectors of badnaviruses, including Cacao swollen shoot virus (CSSV), the most damaging virus affecting cacao (Theobroma cacao L.). The effective... Read More about High-resolution melt and morphological analyses of mealybugs (Hemiptera: Pseudococcidae) from cacao: Tools for the control of Cacao swollen shoot virus spread.

A simple and rapid method for the determination of nicotine in third-hand smoke by liquid chromatography and its application for the assessment of contaminated outdoor communal areas (2016)
Journal Article

Copyright © 2015 John Wiley & Sons, Ltd. This is the first report on the determination of nicotine in third-hand smoke (THS) in outdoor communal areas. The term THS can be defined as the contamination of surfaces by second-hand smoke. This can rema... Read More about A simple and rapid method for the determination of nicotine in third-hand smoke by liquid chromatography and its application for the assessment of contaminated outdoor communal areas.

Rapid detection of pathological mutations and deletions of the haemoglobin beta gene (HBB) by High Resolution Melting (HRM) analysis and Gene Ratio Analysis Copy Enumeration PCR (GRACE-PCR) (2016)
Journal Article

© 2016 The Author(s). Objectives: Inherited disorders of haemoglobin are the world's most common genetic diseases, resulting in significant morbidity and mortality. The large number of mutations associated with the haemoglobin beta gene (HBB) makes g... Read More about Rapid detection of pathological mutations and deletions of the haemoglobin beta gene (HBB) by High Resolution Melting (HRM) analysis and Gene Ratio Analysis Copy Enumeration PCR (GRACE-PCR).

Dual species biofilm culture of Staphylococcus aureus and a bioluminescent strain of Pseudomonas aeruginosa (2016)
Presentation / Conference Contribution

Poster presentation. Introduction Pseudomonas aeruginosa and Staphylococcus aureus are significant pathogens of wounds and the cystic fibrosis lung. There are likely to be complex interactions between the two species, with biofilm co-culture aff... Read More about Dual species biofilm culture of Staphylococcus aureus and a bioluminescent strain of Pseudomonas aeruginosa.

Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: Implications for Alzheimer's disease (2016)
Journal Article

© 2016 The Author(s). Background: Polymorphisms in the gene for phosphatidylinositol binding clathrin assembly protein (PICALM), an endocytic-related protein, are associated with a small, increased risk of developing Alzheimer's disease (AD), strongl... Read More about Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: Implications for Alzheimer's disease.