Outputs (1260)

Energy drinks mixed with alcohol: Are there any risks? (2015)
Journal Article

There have now been a number of publications, including laboratory studies and surveys, on alcohol mixed with energy drinks. Some authors have highlighted problems associated with consumption of this beverage combination, including reduced perception... Read More about Energy drinks mixed with alcohol: Are there any risks?.

Peatland hydrological legacy affects enzyme inhibition and potential DOC release (2015)
Presentation / Conference Contribution

Peatland ecosystems have been drained for agricultural reclamation that has led to degradation and potential loss of a variety of ecosystem services including carbon sequestration. The impact of rewetting by ditch-blocking on dissolved organic carbon... Read More about Peatland hydrological legacy affects enzyme inhibition and potential DOC release.

The voltammetric behaviour of lead at a hand drawn pencil electrode and its trace determination in water by stripping voltammetry (2015)
Journal Article

© The Royal Society of Chemistry 2015. This is the first reported proof of concept application of pencil drawn electrodes (PDEs) for anodic stripping voltammetric determination of Pb2+ or any metal ion. PDEs offer advantages of economics, simplicity... Read More about The voltammetric behaviour of lead at a hand drawn pencil electrode and its trace determination in water by stripping voltammetry.

Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing (2015)
Journal Article

© 2014 Elsevier B.V. In genetic toxicology, risk assessment has traditionally adopted linear dose-responses for any compound that causes genotoxic effects. Increasing evidence of non-linear dose-responses, however, suggests potential cellular toleran... Read More about Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing.

A proposed new bacteriophage subfamily: “Jerseyvirinae” (2015)
Journal Article

© 2015, Springer-Verlag Wien. Based on morphology and comparative nucleotide and protein sequence analysis, a new subfamily of the family Siphoviridae is proposed, named “Jerseyvirinae” and consisting of three genera, “Jerseylikevirus”, “Sp3unalikevi... Read More about A proposed new bacteriophage subfamily: “Jerseyvirinae”.

S-nitrosylation of the thioredoxin-like domains of protein disulfide isomerase and its role in neurodegenerative conditions (2015)
Journal Article

© 2015 Conway and Harris. Correct protein folding and inhibition of protein aggregation is facilitated by a cellular "quality control system" that engages a network of protein interactions including molecular chaperones and the ubiquitin proteasome s... Read More about S-nitrosylation of the thioredoxin-like domains of protein disulfide isomerase and its role in neurodegenerative conditions.

Hormonal and genetic regulation of prostate cancer in Caucasian and Malaysian Chinese ethnic groups (2015)
Thesis

Introduction Prostate Cancer (PC) is the most common cancer in men and the second biggest cause of cancer-related death of men in the Western world. There are significant ethnic differences in the incidence of PC between African Americans, Caucas... Read More about Hormonal and genetic regulation of prostate cancer in Caucasian and Malaysian Chinese ethnic groups.

The expression of alternative splice variants of human epidermal growth factor receptor 2 in invasive breast cancer and cell line models (2015)
Thesis

The Human Epidermal Growth Factor Receptor 2 (HER2) is an oncogene expressed in 25-30% of invasive breast cancers. The HER2 gene encodes an 185kDa transmembrane protein with tyrosine kinase activity. Gene amplification or protein expression of HER2 i... Read More about The expression of alternative splice variants of human epidermal growth factor receptor 2 in invasive breast cancer and cell line models.

The Scd6/Lsm14 protein xRAPB has properties different from RAP55 in selecting mRNA for early translation or intracellular distribution in Xenopus oocytes (2015)
Journal Article

© 2015 Elsevier B.V. Oocytes accumulate mRNAs in the form of maternal ribonucleoprotein (RNP) particles, the protein components of which determine the location and stability of individual mRNAs prior to translation. Scd6/Lsm14 proteins, typified by R... Read More about The Scd6/Lsm14 protein xRAPB has properties different from RAP55 in selecting mRNA for early translation or intracellular distribution in Xenopus oocytes.

SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation (2015)
Journal Article

© 2015 Macmillan Publishers Limited. All rights reserved. Synapsins are key components of the presynaptic neurotransmitter release machinery. Their main role is to cluster synaptic vesicles (SVs) to each other and anchor them to the actin cytoskeleto... Read More about SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation.

New insights into the role of the branched-chain aminotransferase proteins in the human brain (2015)
Journal Article

© 2015 Wiley Periodicals, Inc. The human cytosolic branched-chain aminotransferase (hBCATc) enzyme is strategically located in glutamatergic neurons, where it is thought to provide approximately 30% of de novo nitrogen for brain glutamate synthesis.... Read More about New insights into the role of the branched-chain aminotransferase proteins in the human brain.

Environmental niche variation and evolutionary diversification of the Brachypodium distachyon grass complex species in their native circum-mediterranean range (2015)
Journal Article

© 2015 Botanical Society of America. PREMISE OF THE STUDY: We conducted environmental niche modeling (ENM) of the Brachypodium distachyon s.l. complex, a model group of two diploid annual grasses (B. distachyon, B. stacei) and their derived allotetra... Read More about Environmental niche variation and evolutionary diversification of the Brachypodium distachyon grass complex species in their native circum-mediterranean range.

The future of the biodiversity of the Gran Caldera Scientific Reserve: Translating science into policy to develop an effective management plan (2015)
Report

White paper prepared for the Workshop on ‘The future of the biodiversity of the Gran Caldera Scientific Reserve', celebrated in Malabo, Equatorial Guinea, in June 2015

YAP is essential for tissue tension to ensure vertebrate 3D body shape (2015)
Journal Article

© 2015 Macmillan Publishers Limited. All rights reserved. Vertebrates have a unique 3D body shape in which correct tissue and organ shape and alignment are essential for function. For example, vision requires the lens to be centred in the eye cup whi... Read More about YAP is essential for tissue tension to ensure vertebrate 3D body shape.

Differential responses to woodland character and landscape context by cryptic bats in urban environments (2015)
Journal Article

© 2015 Lintott et al. Urbanisation is one of the most dramatic forms of land use change which relatively few species can adapt to. Determining how and why species respond differently to urban habitats is important in predicting future biodiversity lo... Read More about Differential responses to woodland character and landscape context by cryptic bats in urban environments.

Impacts of artificial lighting on bats: A review of challenges and solutions (2015)
Journal Article

© 2015 Deutsche Gesellschaft für Säugetierkunde. Light pollution is a major emerging issue in biodiversity conservation, and has important implications for policy development and strategic planning. Although research is now addressing the negative im... Read More about Impacts of artificial lighting on bats: A review of challenges and solutions.

H2S and NO signalling in plants (2015)
Presentation / Conference Contribution

Besides already well known actions in animal organisms and described effects on stomata closing in plants, nitric oxide (NO) has an influence on seed dormancy, flower development, root gravitropism, gene expression, plant defence reactions in pathoge... Read More about H2S and NO signalling in plants.

Regional Increase in the Expression of the BCAT Proteins in Alzheimer's Disease Brain: Implications in Glutamate Toxicity (2015)
Journal Article

© 2015 - IOS Press and the authors. All rights reserved. Background: The human branched chain aminotransferases (hBCATm, mitochondrial and hBCATc, cytosolic) are major contributors to brain glutamate production. This excitatory neurotransmitter is th... Read More about Regional Increase in the Expression of the BCAT Proteins in Alzheimer's Disease Brain: Implications in Glutamate Toxicity.

Insulin-dependent GLUT4 trafficking is not regulated by protein SUMOylation in L6 myocytes (2019)
Journal Article

Type-II Diabetes Mellitus (T2DM) is one of the fastest growing public health issues today, consuming 12% of worldwide health budgets and affecting an estimated 400 million people. One of the key pathological traits of this disease is insulin resistan... Read More about Insulin-dependent GLUT4 trafficking is not regulated by protein SUMOylation in L6 myocytes.

Pharmacodynamics of ciprofloxacin against Pseudomonas aeruginosa planktonic and biofilm‐derived cells (2019)
Journal Article

© 2019 The Society for Applied Microbiology The influence of growth phase and state on the survival and recovery of Pseudomonas aeruginosa exposed to ciprofloxacin was investigated using batch culture grown planktonic cells and disaggregated biofilm... Read More about Pharmacodynamics of ciprofloxacin against Pseudomonas aeruginosa planktonic and biofilm‐derived cells.