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A systematic review of machine-learning solutions in anaerobic digestion (2023)
Journal Article
Rutland, H., You, J., Liu, H., Bull, L., & Reynolds, D. (2023). A systematic review of machine-learning solutions in anaerobic digestion. Bioengineering, 10(12), Article 1410. https://doi.org/10.3390/bioengineering10121410

The use of machine learning (ML) in anaerobic digestion (AD) is growing in popularity and improves the interpretation of complex system parameters for better operation and optimisation. This systematic literature review aims to explore how ML is curr... Read More about A systematic review of machine-learning solutions in anaerobic digestion.

HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings (2023)
Journal Article
Mehendale, F. V., Mehendale, F., Homyer, K. M., Clayton, G., Reynolds, D. M., Homyer, K., & Reynolds, D. (2023). HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings. Journal of Global Health Reports, 7, Article e2023052. https://doi.org/10.29392/001c.84488

Disinfection is a mainstay of infection prevention, the importance of which was highlighted throughout the SARS-CoV-2 pandemic. There is frequent misuse of terminology surrounding chlorine solutions in the literature. This leads not only to confusion... Read More about HOCl vs OCl−: clarification on chlorine-based disinfectants used within clinical settings.

Molecular evaluation of the metabolism of estrogenic di(2-ethylhexyl) phthalate in Mycolicibacterium sp. (2023)
Journal Article
Bhattacharyya, M., Dhar, R., Basu, S., Das, A., Reynolds, D. M., & Dutta, T. K. (2023). Molecular evaluation of the metabolism of estrogenic di(2-ethylhexyl) phthalate in Mycolicibacterium sp. Microbial Cell Factories, 22(1), 82. https://doi.org/10.1186/s12934-023-02096-0

Background: Di(2-ethylhexyl) phthalate (DEHP) is a widely detected plasticizer and a priority pollutant of utmost concern for its adverse impact on humans, wildlife and the environment. To eliminate such toxic burden, biological processes are the mos... Read More about Molecular evaluation of the metabolism of estrogenic di(2-ethylhexyl) phthalate in Mycolicibacterium sp..

Slow violence and river abuse: The hidden effect of land use on water quality (2023)
Exhibition / Performance
Fahy, N., Clayton, G., bodman, S., & Reynolds, D. Slow violence and river abuse: The hidden effect of land use on water quality. [Printmaking/Photography]. Exhibited at F block Gallery, Bower Ashton, Bristol. 31 January 2023 - 3 February 2023. (Unpublished)

Researchers from HAS, Dr Gillian Clayton and Professor Darren Reynolds (HAS) and Researchers from ACE Niamh Fahy and Associate Professor Sarah Bodman have been collaborating on a project in Somerset, UK, from which Niamh is using data and samples col... Read More about Slow violence and river abuse: The hidden effect of land use on water quality.

The control of pathogens in stored rainwater using direct electrochemical activation (2022)
Conference Proceeding
Clayton, G., Fox, B., Steer, M., Thorn, R., & Reynolds, D. (2022). The control of pathogens in stored rainwater using direct electrochemical activation. In IWRA Proceedings

Purpose of study or research hypothesis: The main study aim was to control waterborne pathogens using small-scale direct electrochemical activation. Key issue(s) or problem(s) addressed: Rainwater harvesting systems enable households o... Read More about The control of pathogens in stored rainwater using direct electrochemical activation.

Clean water for all (2022)
Digital Artefact
Clayton, G., Steven, J., Thorn, R., & Reynolds, D. (2022). Clean water for all. [Website]

The World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF) estimated that, as of 2020, 2 billion people across the globe did not have access to safely managed drinking water. Ideally, safely managed drinking water should b... Read More about Clean water for all.

Managing potential pathogens in stored rainwater using small-scale in-situ electrochemical activation (2022)
Presentation / Conference
Clayton, G., Fox, B., Steer, M., Thorn, R., & Reynolds, D. (2022, September). Managing potential pathogens in stored rainwater using small-scale in-situ electrochemical activation. Presented at International Water Association World Water Congress and Exhibition, Copenhagen

Rainwater can be a lifeline for many people who do not have piped water supplies, experience dry seasons, or live-in fresh water scarce areas. The quality of stored rainwater can deteriorate over time, due to increasing concentrations of contaminants... Read More about Managing potential pathogens in stored rainwater using small-scale in-situ electrochemical activation.

The control of waterborne pathogenic bacteria in fresh water using a biologically active filter (2022)
Journal Article
Steven, J. A. C., Thorn, R. M. S., Robinson, G. M., Turner, D., Lee, J. E., & Reynolds, D. M. (2022). The control of waterborne pathogenic bacteria in fresh water using a biologically active filter. npj Clean Water, 5(1), 30. https://doi.org/10.1038/s41545-022-00169-y

The aim of this study was to investigate the control of three species of bacteria commonly associated with biologically contaminated water, using biofiltration. In this study, a laboratory-scale biofilter system was used to investigate the control of... Read More about The control of waterborne pathogenic bacteria in fresh water using a biologically active filter.

A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India (2022)
Journal Article
Fox, B., Thorn, R., Dutta, T., Bowes, M., Read, D., & Reynolds, D. (2022). A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India. Science of the Total Environment, 842, 156848. https://doi.org/10.1016/j.scitotenv.2022.156848

The quality and health of many of our vital freshwater systems are poor. To tackle this with ever increasing pressures from anthropogenic and climatic changes, we must improve water quality monitoring and devise and implement more appropriate water q... Read More about A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India.

The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model (2022)
Journal Article
Perrin, E. M., Thorn, R. M., Sargeant, S. L., Attridge, J. W., & Reynolds, D. M. (2022). The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model. Frontiers in Microbiology, 13, Article 817976. https://doi.org/10.3389/fmicb.2022.817976

Dissolved organic matter (DOM) is ubiquitous throughout aquatic systems. Fluorescence techniques can be used to characterize the fluorescing proportion of DOM, aquatic fluorescent organic matter (AFOM). AFOM is conventionally named in association wit... Read More about The in situ production of aquatic fluorescent organic matter in a simulated freshwater laboratory model.

Marimo actuated rover systems (2022)
Journal Article
Phillips, N., Draper, T. C., Mayne, R., Reynolds, D. M., & Adamatzky, A. (2022). Marimo actuated rover systems. Journal of Biological Engineering, 16(1), Article 3. https://doi.org/10.1186/s13036-021-00279-0

Background: The potential to directly harness photosynthesis to make actuators, biosensors and bioprocessors has been previously demonstrated in the literature. Herein, this capability has been expanded to more advanced systems — Marimo Actuated Rove... Read More about Marimo actuated rover systems.

The efficacy of chlorine-based disinfectants against planktonic and biofilm bacteria for decentralised point-of-use drinking water (2021)
Journal Article
Clayton, G. E., Thorn, R., & Reynolds, D. (2021). The efficacy of chlorine-based disinfectants against planktonic and biofilm bacteria for decentralised point-of-use drinking water. npj Clean Water, 4(1), Article 48. https://doi.org/10.1038/s41545-021-00139-w

Chlorine solutions are used extensively for the production of biologically safe drinking water. The capability of point-of-use [POU] drinking water treatment systems has gained interest in locations where centralised treatment systems and distributio... Read More about The efficacy of chlorine-based disinfectants against planktonic and biofilm bacteria for decentralised point-of-use drinking water.

Real-time detection of volatile metabolites enabling species-level discrimination of bacterial biofilms associated with wound infection (2021)
Journal Article
Slade, E., Thorn, R., Young, A., & Reynolds, D. (2022). Real-time detection of volatile metabolites enabling species-level discrimination of bacterial biofilms associated with wound infection. Journal of Applied Microbiology, 132(3), 1558-1572. https://doi.org/10.1111/jam.15313

Aims: The main aim of this study was to investigate the real-time detection of volatile metabolites for the species-level discrimination of pathogens associated with clinically relevant wound infection, when grown in a collagen wound biofilm model. M... Read More about Real-time detection of volatile metabolites enabling species-level discrimination of bacterial biofilms associated with wound infection.

Laboratory in-situ production of autochthonous and allochthonous fluorescent organic matter by freshwater bacteria (2021)
Journal Article
Fox, B. G., Thorn, R. M. S., & Reynolds, D. M. (2021). Laboratory in-situ production of autochthonous and allochthonous fluorescent organic matter by freshwater bacteria. Microorganisms, 9(8), Article 1623. https://doi.org/10.3390/microorganisms9081623

This work investigates the origin and range of fluorescent organic matter (FOM) produced in-situ by environmentally sourced freshwater bacteria. Aquatic FOM is an essential component in global carbon cycling and is generally classified as either auto... Read More about Laboratory in-situ production of autochthonous and allochthonous fluorescent organic matter by freshwater bacteria.

Sediment and surface water microplastic contamination along the Ganges River, from the Himalayan foothills to the tidal reach downstream of Kolkata, India (2021)
Presentation / Conference
Nel, H., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Sediment and surface water microplastic contamination along the Ganges River, from the Himalayan foothills to the tidal reach downstream of Kolkata, India. Presented at EGU General Assembly 2021

Twenty rivers have been estimated previously to account for almost 70% of global plastic emissions to the marine environment. Of these, the Ganges River was second only to the Yangtze River. Yet, scale and complexity of the Ganges River network make... Read More about Sediment and surface water microplastic contamination along the Ganges River, from the Himalayan foothills to the tidal reach downstream of Kolkata, India.

A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India (2021)
Presentation / Conference
Fox, B., Thorn, R., Dutta, T., & Reynolds, D. (2021, April). A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India. Presented at EGU General Assembly 2021

With increasing pressures on water resources due to population, industrialization, agriculture, urbanization and climatic changes, improved temporal and spatial understanding of water quality is required. The development of new monitoring parameters,... Read More about A case study: The deployment of a novel in situ fluorimeter for monitoring biological contamination within the urban surface waters of Kolkata, India.

Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts (2021)
Presentation / Conference
Richards, L. A., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts. Presented at EGU General Assembly 2021

In a basin-wide survey of the River Ganga and key tributaries, from the Himalayan source to the Bay of Bengal in India, we aim to improve the conceptual understanding of downstream water quality trends along > 2000 km. Here we explore the spatial di... Read More about Water quality across the River Ganga basin in India: Trends, dominant geochemical processes and impacts.

Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin (2021)
Presentation / Conference
Khamis, K., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin. Presented at EGU General Assembly 2021

There is increasing interest in monitoring spatial variability in biogeochemical processes using field deployable sensors. Despite this, rigorous assessments of accuracy and optimal sensor configurations remain limited for such applications. We under... Read More about Using in-situ sensors to quantify spatial variability in nutrient concentrations across the Ganges river basin.

Taking the pulse of Mother Ganga - Revealing the visible and invisible water pollution crisis along the Ganges River (2021)
Presentation / Conference
Krause, S., Fox, B., Reynolds, D., Thorn, R., Clayton, G., Perrin, E., …Magnone, D. (2021, April). Taking the pulse of Mother Ganga - Revealing the visible and invisible water pollution crisis along the Ganges River. Presented at EGU General Assembly 2021

It is probably hard to overestimate the significance of the River Ganges for its spiritual, cultural and religious importance. As the worlds’ most populated river basin and a major water resource for the 400 million people inhabiting its catchment, t... Read More about Taking the pulse of Mother Ganga - Revealing the visible and invisible water pollution crisis along the Ganges River.

Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms (2020)
Conference Proceeding
Clayton, G., Thorn, R., & Reynolds, D. (in press). Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms

Summary of key findings Direct disinfection of established Pseudomonas aeruginosa biofilms by electrochemically activated solutions [ECAS] exhibited significantly greater anti-biofilm activity compared to NaOCl and HOCl at free chlorine concentratio... Read More about Biofilm management; Investigating the inhibitory effects of chlorine-based disinfectants on biofilms.

An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics (2019)
Journal Article
Slade, E. A., Thorn, R. M. S., Young, A., & Reynolds, D. M. (2019). An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics. BMC Microbiology, 19(1), Article 310. https://doi.org/10.1186/s12866-019-1682-5

Background The majority of in vitro studies of medically relevant biofilms involve the development of biofilm on an inanimate solid surface. However, infection in vivo consists of biofilm growth on, or suspended within, the semi-solid matrix of the... Read More about An in vitro collagen perfusion wound biofilm model; with applications for antimicrobial studies and microbial metabolomics.

Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment (2019)
Journal Article
Clayton, G. E., Thorn, R. M., & Reynolds, D. M. (2019). Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment. Frontiers in Environmental Science, 7, Article 35. https://doi.org/10.3389/fenvs.2019.00035

© 2019 Clayton, Thorn and Reynolds. Point-of-use (POU) drinking water treatment systems provide solutions for communities where centralized facilities are unavailable. Effective POU systems treat and reduce the number of pathogens in POU water suppl... Read More about Comparison of trihalomethane formation using chlorine-based disinfectants within a model system; Applications within point-of-use drinking water treatment.

Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system (2018)
Journal Article
Fox, B. G., Thorn, R. M., Anesio, A. M., Cox, T., Attridge, J. W., & Reynolds, D. M. (2019). Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system. Water, 11(1), Article 10. https://doi.org/10.3390/w11010010

© 2018 by the authors. Organic matter (OM) has an essential biogeochemical influence along the hydrological continuum and within aquatic ecosystems. Organic matter derived via microbial processes was investigated within a range of model freshwater sa... Read More about Microbial processing and production of aquatic fluorescent organic matter in a model freshwater system.

CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML (2018)
Journal Article
Anderson, E., Mehta, P., Heywood, J., Rees, B., Bone, H., Robinson, G., …Mayer, L. (2018). CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML. Leukemia Research, 74, 121-129. https://doi.org/10.1016/j.leukres.2018.08.007

© 2018 Elsevier Ltd CPX-351, a liposomal formulation co-encapsulating cytarabine and daunorubicin (DNR) in a synergistic 5:1 M ratio, has shown favourable response in newly diagnosed elderly high-risk AML. This study assessed intracellular ara-CTP le... Read More about CPX-351 exhibits hENT-independent uptake and can be potentiated by fludarabine in leukaemic cells lines and primary refractory AML.

Visualization of phage genomic data: Comparative genomics and publication-quality diagrams (2018)
Book Chapter
Reynolds, D. M., Turner, D., Sutton, J. M., Reynolds, D. M., Sim, E. M., & Petty, N. K. (2018). Visualization of phage genomic data: Comparative genomics and publication-quality diagrams. In R. Lavigne, A. M. Kropinski, & M. Clokie (Eds.), Bacteriophages. Methods in Molecular Biology (239-260). New York, NY: Springer. https://doi.org/10.1007/978-1-4939-7343-9_18

© 2018, Springer Science+Business Media LLC. The presentation of bacteriophage genomes as diagrams allows the location and organization of features to be communicated in a clear and effective manner. A wide range of software applications are availabl... Read More about Visualization of phage genomic data: Comparative genomics and publication-quality diagrams.

Comparative analysis of 37 Acinetobacter bacteriophages (2017)
Journal Article
Reynolds, D. M., Kropinski, A. M., Turner, D., Ackermann, H. W., Kropinski, A., Lavigne, R., …Reynolds, D. M. (2018). Comparative analysis of 37 Acinetobacter bacteriophages. Viruses, 10(1), 5. https://doi.org/10.3390/v10010005

© 2017 by the authors. Licensee MDPI, Basel, Switzerland. Members of the genus Acinetobacter are ubiquitous in the environment and the multipledrug resistant species A. baumannii is of significant clinical concern. This clinical relevance is currentl... Read More about Comparative analysis of 37 Acinetobacter bacteriophages.

Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS) (2017)
Journal Article
May, J., Robinson, G., Thorn, R., & Reynolds, D. (2017). Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS). Mutagenesis, 32(6), 622-623. https://doi.org/10.1093/mutage/gex033

Electrochemically activated solutions (ECAS) are of interest as potential disinfectants due to high biocidal activity against many microorganisms. They are widely used clinically in some countries (decontamination of surgical instruments and wounds),... Read More about Cytotoxicity and genotoxicity of electrochemically activated solutions (ECAS).

Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes (2017)
Journal Article
Clayton, G., Thorn, R., & Reynolds, D. M. (2019). Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes. Journal of Water Process Engineering, 30, Article 100480. https://doi.org/10.1016/j.jwpe.2017.08.018

© 2017 Elsevier Ltd Approximately 800 million people live without clean drinking water. Diarrhoea is responsible for between 1.7 and 2 million deaths each year (primarily children) which are the result of poor drinking water quality and sanitation. T... Read More about Development of a novel off-grid drinking water production system integrating electrochemically activated solutions and ultrafiltration membranes.

The in situ bacterial production of fluorescent organic matter; An investigation at a species level (2017)
Journal Article
Fox, B. G., Thorn, R. M. S., Anesio, A. M., & Reynolds, D. M. (2017). The in situ bacterial production of fluorescent organic matter; An investigation at a species level. Water Research, 125, 350-359. https://doi.org/10.1016/j.watres.2017.08.040

© 2017 The Authors Aquatic dissolved organic matter (DOM) plays an essential role in biogeochemical cycling and transport of organic matter throughout the hydrological continuum. To characterise microbially-derived organic matter (OM) from common env... Read More about The in situ bacterial production of fluorescent organic matter; An investigation at a species level.

Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions (2017)
Journal Article
Thorn, R., Pendred, J., & Reynolds, D. M. (2017). Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions. Food Microbiology, 68, 41-50. https://doi.org/10.1016/j.fm.2017.06.018

© 2017 The main aim of this study was to assess the antimicrobial efficacy of electrochemically activated fog (ECAF) for reducing the microbial bio-burden on artificially inoculated fresh produce held under cooled (cucumber and vine tomatoes) or cold... Read More about Assessing the antimicrobial potential of aerosolised electrochemically activated solutions (ECAS) for reducing the microbial bio-burden on fresh food produce held under cooled or cold storage conditions.

In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry (2017)
Journal Article
Slade, E. A., Thorn, R. M., Lovering, A. M., Young, A., & Reynolds, D. M. (2017). In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry. Journal of Applied Microbiology, 123(1), 233-245. https://doi.org/10.1111/jam.13473

© 2017 The Society for Applied Microbiology Aims: To determine if bacterial species responsible for clinically relevant wound infection produce specific volatile profiles that would allow their speciation. Methods and Results: Selected ion flow tube-... Read More about In vitro discrimination of wound-associated bacteria by volatile compound profiling using selected ion flow tube-mass spectrometry.

Characterisation and genome sequence of the lytic Acinetobacter baumannii bacteriophage vB-AbaS-Loki (2017)
Journal Article
Turner, D., Wand, M. E., Briers, Y., Lavigne, R., Sutton, J. M., & Reynolds, D. M. (2017). Characterisation and genome sequence of the lytic Acinetobacter baumannii bacteriophage vB-AbaS-Loki. PLoS ONE, 12(2), e0172303. https://doi.org/10.1371/journal.pone.0172303

© 2017 Turner et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cred... Read More about Characterisation and genome sequence of the lytic Acinetobacter baumannii bacteriophage vB-AbaS-Loki.

Dissolved organic carbon transformations and microbial community response to variations in recharge waters in a shallow carbonate aquifer (2016)
Journal Article
Cooper, K. J., Whitaker, F. F., Anesio, A. M., Naish, M., Reynolds, D. M., & Evans, E. L. (2016). Dissolved organic carbon transformations and microbial community response to variations in recharge waters in a shallow carbonate aquifer. Biogeochemistry, 129(1-2), 215-234. https://doi.org/10.1007/s10533-016-0226-4

© 2016, The Author(s). In carbonate aquifers, dissolved organic carbon from the surface drives heterotrophic metabolism, generating CO2 in the subsurface. Although this has been a proposed mechanism for enhanced dissolution at the water table, respir... Read More about Dissolved organic carbon transformations and microbial community response to variations in recharge waters in a shallow carbonate aquifer.

Fluorescence spectroscopy for wastewater monitoring: A review (2016)
Journal Article
Carstea, E. M., Carstea, E., Bridgeman, J., Baker, A., & Reynolds, D. M. (2016). Fluorescence spectroscopy for wastewater monitoring: A review. Water Research, 95, 205-219. https://doi.org/10.1016/j.watres.2016.03.021

© 2016. Wastewater quality is usually assessed using physical, chemical and microbiological tests, which are not suitable for online monitoring, provide unreliable results, or use hazardous chemicals. Hence, there is an urgent need to find a rapid an... Read More about Fluorescence spectroscopy for wastewater monitoring: A review.

Genome sequence of vB_AbaS_TRS1, a viable prophage isolated from Acinetobacter baumannii strain A118 (2016)
Journal Article
Turner, D., Wand, M. E., Sutton, J. M., Centron, D., Kropinski, A. M., & Reynolds, D. M. (2016). Genome sequence of vB_AbaS_TRS1, a viable prophage isolated from Acinetobacter baumannii strain A118. Genome Announcements, 4(5), e01051-16. https://doi.org/10.1128/genomeA.01051-16

© 2016 Turner et al. A novel temperate phage, vB_AbaS_TRS1, was isolated from cultures of Acinetobacter baumannii strain A118 that had been exposed to mitomycin C. Phage TRS1 belongs to the Siphoviridae family of bacteriophages and encapsulates a 40,... Read More about Genome sequence of vB_AbaS_TRS1, a viable prophage isolated from Acinetobacter baumannii strain A118.

Preface: From the coordinating editor (2016)
Journal Article
Furze, J. N., Swing, K., Gupta, A. K., McClatchey, R., & Reynolds, D. M. (2016). Preface: From the coordinating editor. https://doi.org/10.1007/978-3-319-43901-3

This edited volume focuses on how we can protect our environment and enhance environmental sustainability when faced with changes and pressures imposed by our expansive needs. The volume unites multiple subject areas within sustainability, enabling t... Read More about Preface: From the coordinating editor.

A proposed new bacteriophage subfamily: “Jerseyvirinae” (2015)
Journal Article
Anany, H., Switt, A. I. M., De Lappe, N., Ackermann, H., Reynolds, D. M., Kropinski, A. M., …Turner, D. (2015). A proposed new bacteriophage subfamily: “Jerseyvirinae”. Archives of Virology, 160(4), 1021-1033. https://doi.org/10.1007/s00705-015-2344-z

© 2015, Springer-Verlag Wien. Based on morphology and comparative nucleotide and protein sequence analysis, a new subfamily of the family Siphoviridae is proposed, named “Jerseyvirinae” and consisting of three genera, “Jerseylikevirus”, “Sp3unalikevi... Read More about A proposed new bacteriophage subfamily: “Jerseyvirinae”.

Aquatic Organic Matter Fluorescence (2014)
Book
Coble, P., Lead, J., Baker, A., Reynolds, D. M., & Spencer, R. (2014). R. Spencer, P. Coble, J. Lead, A. Baker, & D. M. Reynolds (Eds.), Aquatic Organic Matter Fluorescence. New York, USA: Cambridge University Press

This is the first comprehensive text on the theory and practice of aquatic organic matter fluorescence analysis, written by the experts who pioneered the research area. This book covers the topic in the broadest possible terms, providing a common ref... Read More about Aquatic Organic Matter Fluorescence.

Principles of fluorescence (2014)
Book Chapter
Reynolds, D. (2014). Principles of fluorescence. In P. Coble, J. Lead, A. Baker, D. Reynolds, & R. Spencer (Eds.), Aquatic Organic Matter FluorescenceCambridge University Press

Characterisation of dissolved organic matter fluorescence properties by PARAFAC analysis and thermal quenching (2014)
Journal Article
Carstea, E. M., Baker, A., Bieroza, M., Reynolds, D. M., & Bridgeman, J. (2014). Characterisation of dissolved organic matter fluorescence properties by PARAFAC analysis and thermal quenching. Water Research, 61, 152-161. https://doi.org/10.1016/j.watres.2014.05.013

The fluorescence intensity of dissolved organic matter (DOM) in aqueous samples is known to be highly influenced by temperature. Although several studies have demonstrated the effect of thermal quenching on the fluorescence of DOM, no research has be... Read More about Characterisation of dissolved organic matter fluorescence properties by PARAFAC analysis and thermal quenching.

Low light optical detection of whole-cell bioluminescent bacterial bioreporters for visualisation of surface decontamination using nonthermal plasma (2013)
Presentation / Conference
Robinson, G. M., Thorn, R., Hancock, C., & Reynolds, D. M. (2013, May). Low light optical detection of whole-cell bioluminescent bacterial bioreporters for visualisation of surface decontamination using nonthermal plasma. Paper presented at 3rd International Conference on Bio-Sensing Technology, Sitges, Spain

Introduction: Maintenance of a clean, uncontaminated healthcare environment is instrumental in the delivery of modern healthcare. Nonthermal plasma is a technology with potential applications for sterilisation and disinfection in biological and medi... Read More about Low light optical detection of whole-cell bioluminescent bacterial bioreporters for visualisation of surface decontamination using nonthermal plasma.

Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay (2013)
Journal Article
Reynolds, D. M., Thorn, R. M., Thorn, R., Reynolds, D. M., & Robinson, G. M. (2013). Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay. Antimicrobial Agents and Chemotherapy, 57(5), 2216-2225. https://doi.org/10.1128/AAC.02589-12

The main aim of this study was to develop a standardized experimental assay to enable differential antimicrobial comparisons of test biocidal aerosols. This study represents the first chlorine-matched comparative assessment of the antimicrobial activ... Read More about Comparative antimicrobial activities of aerosolized sodium hypochlorite, chlorine dioxide, and electrochemically activated solutions evaluated using a novel standardized assay.

CoreGenes3.5: A webserver for the determination of core genes from sets of viral and small bacterial genomes (2013)
Journal Article
Turner, D., Reynolds, D., Seto, D., & Mahadevan, P. (2013). CoreGenes3.5: A webserver for the determination of core genes from sets of viral and small bacterial genomes. BMC Research Notes, 6(1), 140. https://doi.org/10.1186/1756-0500-6-140

Background: CoreGenes3.5 is a webserver that determines sets of core genes from viral and small bacterial genomes as an automated batch process. Previous versions of CoreGenes have been used to classify bacteriophage genomes and mine data from pathog... Read More about CoreGenes3.5: A webserver for the determination of core genes from sets of viral and small bacterial genomes.

Detection of intracellular ara-C/ara-CTP following treatment with the new anti-leukemic drug elacytarabine using a bioluminescent bacterial biosensor (2013)
Presentation / Conference
Robinson, G. M., Anderson, E., Salisbury, V., Mehta, P., Sandvold, M., & Reynolds, D. M. (2013, April). Detection of intracellular ara-C/ara-CTP following treatment with the new anti-leukemic drug elacytarabine using a bioluminescent bacterial biosensor. Poster presented at American Association for Cancer Research Annual Meeting, Washington D.C., USA

Cytarabine (ara-C) is an analogue of deoxycytidine with an established role in treating AML. Cytarabine depends on the human equilibrative nucleoside transporter-1 (hENT-1) for cellular entry (1). Loss of hENT-1 function in vitro has been shown to re... Read More about Detection of intracellular ara-C/ara-CTP following treatment with the new anti-leukemic drug elacytarabine using a bioluminescent bacterial biosensor.

The effect of long-term storage on the physiochemical and bactericidal properties of electrochemically activated solutions (2013)
Journal Article
Robinson, G., Thorn, R., & Reynolds, D. (2013). The effect of long-term storage on the physiochemical and bactericidal properties of electrochemically activated solutions. International Journal of Molecular Sciences, 14(1), 457-469. https://doi.org/10.3390/ijms14010457

Electrochemically activated solutions (ECAS) are generated by electrolysis of NaCl solutions, and demonstrate broad spectrum antimicrobial activity and high environmental compatibility. The biocidal efficacy of ECAS at the point of production is wide... Read More about The effect of long-term storage on the physiochemical and bactericidal properties of electrochemically activated solutions.

Characterization of the Salmonella bacteriophage vB_SenS-Ent1 (2012)
Journal Article
Turner, D., Hezwani, M., Nelson, S., Salisbury, V., & Reynolds, D. M. (2012). Characterization of the Salmonella bacteriophage vB_SenS-Ent1. Journal of General Virology, 93(9), 2046-2056. https://doi.org/10.1099/vir.0.043331-0

The bacteriophage vB_SenS-Ent1 (Ent1) is a member of the family Siphoviridae of tailed bacteriophages and infects a broad range of serovars of the enteric pathogen Salmonella enterica. The virion particle is composed of an icosahedral head 64 nm in d... Read More about Characterization of the Salmonella bacteriophage vB_SenS-Ent1.

Characterization of the Salmonella bacteriophage vB_SenS-Ent1 (2012)
Journal Article
Reynolds, D., Nelson, S., Turner, D., Hezwani, M., Nelson, S., Salisbury, V., & Reynolds, D. M. (2012). Characterization of the Salmonella bacteriophage vB_SenS-Ent1. Journal of General Virology, 93(PART 9), 2046-2056. https://doi.org/10.1099/vir.0.043331-0

The bacteriophage vB_SenS-Ent1 (Ent1) is a member of the family Siphoviridae of tailed bacteriophages and infects a broad range of serovars of the enteric pathogen Salmonella enterica. The virion particle is composed of an icosahedral head 64 nm in d... Read More about Characterization of the Salmonella bacteriophage vB_SenS-Ent1.

Electrochemically activated solutions: Evidence for antimicrobial efficacy and applications in healthcare environments (2012)
Journal Article
Lee, S. W., Thorn, R., Robinson, G., Greenman, J., & Reynolds, D. M. (2012). Electrochemically activated solutions: Evidence for antimicrobial efficacy and applications in healthcare environments. European Journal of Clinical Microbiology and Infectious Diseases, 31(5), 641-653. https://doi.org/10.1007/s10096-011-1369-9

Due to the limitations associated with the use of existing biocidal agents, there is a need to explore new methods of disinfection to help maintain effective bioburden control, especially within the healthcare environment. The transformation of low m... Read More about Electrochemically activated solutions: Evidence for antimicrobial efficacy and applications in healthcare environments.

Constructing a coherent STEM strategy with schools (2012)
Journal Article
Hooper, A. P., Reynolds, D. M., & Lavelle, M. (2012). Constructing a coherent STEM strategy with schools

Most universities run STEM enrichment activities with local schools. At UWE we have run activities with respect to mathematics (Maths Challenge, Maths Event Day, FUNMaths Roadshows), Engineering (Engineering activity day, Bloodhound), Science (Scienc... Read More about Constructing a coherent STEM strategy with schools.

Application of bacterial bioluminescence to assess the efficacy of fast-acting biocides (2011)
Journal Article
Robinson, G., Tonks, K. M., Thorn, R., & Reynolds, D. M. (2011). Application of bacterial bioluminescence to assess the efficacy of fast-acting biocides. Antimicrobial Agents and Chemotherapy, 55(11), 5214-5219. https://doi.org/10.1128/AAC.00489-11

Traditional microbiological techniques are used to provide reliable data on the rate and extent of kill for a range of biocides. However, such techniques provide very limited data regarding the initial rate of kill of fast-acting biocides over very s... Read More about Application of bacterial bioluminescence to assess the efficacy of fast-acting biocides.

Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro (2011)
Journal Article
Thorn, R., Reynolds, D. M., & Greenman, J. (2011). Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro. Journal of Microbiological Methods, 84(2), 258-264. https://doi.org/10.1016/j.mimet.2010.12.001

Volatile compounds (VCs) are produced by all microorganisms as part of their normal metabolism. The aim of this study was to determine whether bacterial VC profiles could be used to discriminate between selected bacterial species and strains in vitro... Read More about Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro.

Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro (2011)
Journal Article
Thorn, R., Reynolds, D. M., & Greenman, J. (2011). Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro. Journal of Microbiological Methods, 84(2), 258-264. https://doi.org/10.1016/j.mimet.2010.12.001

Volatile compounds (VCs) are produced by all microorganisms as part of their normal metabolism. The aim of this study was to determine whether bacterial VC profiles could be used to discriminate between selected bacterial species and strains in vitro... Read More about Multivariate analysis of bacterial volatile compound profiles for discrimination between selected species and strains in vitro.

Requirements for phylogenetic tree visualisation: A user driven approach (2010)
Presentation / Conference
Hale, P., Solomonides, T., Beeson, I., Willey, N., Bultitude, K., & Reynolds, D. M. (2010, November). Requirements for phylogenetic tree visualisation: A user driven approach. Poster presented at BBSRC/AHRC Workshop on "The Challenges of Visualising Biological Data", Bristol, UK

BBSRC/AHRC Workshop on "The Challenges of Visualising Biological Data" Date: 16-17 November 2010 Venue: The Thistle Grand Hotel, Bristol BBSRC - http://www.bbsrc.ac.uk/news/events/1011-visualising-biological-data.aspx AHRC -http://www.ahrc.... Read More about Requirements for phylogenetic tree visualisation: A user driven approach.

Continuous fluorescence excitation-emission matrix monitoring of river organic matter (2010)
Journal Article
Carstea, E. M., Baker, A., Bieroza, M., & Reynolds, D. M. (2010). Continuous fluorescence excitation-emission matrix monitoring of river organic matter. Water Research, 44(18), 5356-5366. https://doi.org/10.1016/j.watres.2010.06.036

Real-time fluorescence monitoring has been mostly performed in marine systems, with little progress being made in the application of fluorescence excitation-emission matrix (EEM) spectroscopy, especially for freshwater monitoring. This paper presents... Read More about Continuous fluorescence excitation-emission matrix monitoring of river organic matter.

Evaluation of the efficacy of electrochemically activated solutions against nosocomial pathogens and bacterial endospores (2010)
Journal Article
Salisbury, V. C., Robinson, G. M., Lee, S. W., Greenman, J., & Reynolds, D. M. (2010). Evaluation of the efficacy of electrochemically activated solutions against nosocomial pathogens and bacterial endospores. Letters in Applied Microbiology, 50(3), 289-294. https://doi.org/10.1111/j.1472-765X.2009.02790.x

Aims: Electrochemically activated solutions (ECAS) are generated from halide salt solutions via specially designed electrolytic cells. The active solutions are known to possess high biocidal activity against a wide range of target microbial species,... Read More about Evaluation of the efficacy of electrochemically activated solutions against nosocomial pathogens and bacterial endospores.

The effect of temperature on the fluorescence of DOM (2009)
Presentation / Conference
Reynolds, D. M., Baker, A., & Carstea, E. (2009, December). The effect of temperature on the fluorescence of DOM. Paper presented at American Geophysical Union Fall Meeting, San Francisco, USA

It is understood that all fluorescence analyses essentially observes the fluorescence of a given sample in a 'quenched state'. Even so, detailed literature concerning the effects of lower temperatures (below 4 degrees Celsius) is surprisingly sparse.... Read More about The effect of temperature on the fluorescence of DOM.

Real-time monitoring of river water quality using in-line continuous acquisition of fluorescence excitation and emission matrices (2009)
Presentation / Conference
Reynolds, D. M. (2009, December). Real-time monitoring of river water quality using in-line continuous acquisition of fluorescence excitation and emission matrices. Poster presented at American Geophysical Union Fall Meeting, San Francisco, USA

Birmingham, UK. River water was diverted to a portable laboratory via a continuous flow pump and filter system. Fluorescence excitation-emission matrices data was recorded every 3 minutes using a flow cell (1cm pathlength) coupled to a fiber optic pr... Read More about Real-time monitoring of river water quality using in-line continuous acquisition of fluorescence excitation and emission matrices.

Changes in freshwater organic matter fluorescence intensity with freezing/thawing and dehydration/rehydration (2009)
Journal Article
Hudson, N., Baker, A., Reynolds, D. M., Carliell-Marquet, C., & Ward, D. (2009). Changes in freshwater organic matter fluorescence intensity with freezing/thawing and dehydration/rehydration. Journal of Geophysical Research, 114(4), G00F08. https://doi.org/10.1029/2008JG000915

The effects of photodegradation and biodegradation upon aquatic organic matter lability have been extensively researched in all aquatic systems because of the impact of these. processes upon carbon cycling, with most studies undertaken on the dissolv... Read More about Changes in freshwater organic matter fluorescence intensity with freezing/thawing and dehydration/rehydration.

Can fluorescence spectrometry be used as a surrogate for the Biochemical Oxygen Demand (BOD) test in water quality assessment? An example from South West England (2008)
Journal Article
Hudson, N., Baker, A., Reynolds, D. M., Ward, D., Brunsdon, C., Carliell-Marquet, C., & Browning, S. (2008). Can fluorescence spectrometry be used as a surrogate for the Biochemical Oxygen Demand (BOD) test in water quality assessment? An example from South West England. Science of the Total Environment, 391(1), 149-158. https://doi.org/10.1016/j.scitotenv.2007.10.054

The fluorescence intensities of tryptophan-like, tyrosine-like and humic-like materials were determined using excitation-emission-matrices (EEMs) for a wide range of samples including natural surface waters, sewage and industrial effluents and waters... Read More about Can fluorescence spectrometry be used as a surrogate for the Biochemical Oxygen Demand (BOD) test in water quality assessment? An example from South West England.

Fluorescence analysis of dissolved organic matter in natural, waste and polluted waters - A review (2007)
Journal Article
Hudson, N., Baker, A., & Reynolds, D. M. (2007). Fluorescence analysis of dissolved organic matter in natural, waste and polluted waters - A review. River Research and Applications, 23(6), 631-649. https://doi.org/10.1002/rra.1005

Dissolved organic matter (DOM) in aquatic systems originates from a range of sources. Some is allochthonous, transported from the surrounding landscape to the water body, and is derived from and influenced by the geology, land use and hydrology of it... Read More about Fluorescence analysis of dissolved organic matter in natural, waste and polluted waters - A review.

Rapid and direct determination of tryptophan in water using synchronous fluorescence spectroscopy (2003)
Journal Article
Reynolds, D. M. (2003). Rapid and direct determination of tryptophan in water using synchronous fluorescence spectroscopy. Water Research, 37(13), 3055-3060. https://doi.org/10.1016/S0043-1354%2803%2900153-2

Water samples from lakes situated in and around the area of Tsukuba Science City, Ibaraki Prefecture, Japan, were analysed using synchronous fluorescence spectroscopy and HPLC. The spectra revealed a major emission peak (λemm) at 340nm corresponding... Read More about Rapid and direct determination of tryptophan in water using synchronous fluorescence spectroscopy.

The differentiation of biodegradable and non-biodegradable dissolved organic matter in wastewaters using fluorescence spectroscopy (2002)
Journal Article
Reynolds, D. M. (2002). The differentiation of biodegradable and non-biodegradable dissolved organic matter in wastewaters using fluorescence spectroscopy. Journal of Chemical Technology and Biotechnology, 77(8), 965-972. https://doi.org/10.1002/jctb.664

The chemical and biochemical oxygen demand values of a number of synthetic and wastewater samples were determined using fluorescence spectroscopy. Treated and untreated sewage samples were obtained from a local sewage treatment works while synthetic... Read More about The differentiation of biodegradable and non-biodegradable dissolved organic matter in wastewaters using fluorescence spectroscopy.