All Outputs (128)

Inactivation of Listeria monocytogenes in raw and hot smoked trout fillets by high hydrostatic pressure processing combined with liquid smoke and freezing (2020)
Journal Article

High hydrostatic pressure (HHP; 200 MPa for 15 min), liquid smoke (0.50%, v/v) and freezing (−80 °C, overnight) was used to eliminate Listeria monocytogenes in BHI broth, raw and smoked trout. The bactericidal effect of liquid smoke solutions (L9 and... Read More about Inactivation of Listeria monocytogenes in raw and hot smoked trout fillets by high hydrostatic pressure processing combined with liquid smoke and freezing.

Predicting the susceptibility of animals to COVID-19 (2020)
Digital Artefact

No Abstract

Alcohol and micronutrient-induced regulation of Aβ load and Tau hyperphosphorylation through modulation of mitochondrial fusion/fission pathways (2020)
Thesis

Introduction and aims: Alzheimer’s disease (AD) has for decades been associated with increased accumulation of brain amyloid β peptides (Aβ) and phosphorylated tau. Unfortunately, targeted therapy to Aβ in particular has not been successful resulting... Read More about Alcohol and micronutrient-induced regulation of Aβ load and Tau hyperphosphorylation through modulation of mitochondrial fusion/fission pathways.

Nitric oxide, other reactive signalling compounds, redox, and reductive stress (2020)
Journal Article

Nitric oxide (NO) and other reactive nitrogen species (RNS) are key signalling molecules in plants, but they do not work in isolation. NO is produced in cells, often increased in response to stress conditions, but many other reactive compounds used i... Read More about Nitric oxide, other reactive signalling compounds, redox, and reductive stress.

Future brief: Pollinators: Importance for nature and human well-being, drivers of decline and the need for monitoring (2020)
Report

Pollinators are vital to our wellbeing and the survival of nature. By helping plants reproduce, pollinators support a steady supply of healthy and economically valuable food for humans and prop up entire ecosystems. However, we are at risk of losing... Read More about Future brief: Pollinators: Importance for nature and human well-being, drivers of decline and the need for monitoring.

Breath analysis for detection of viral infection, the current position of the field (2020)
Journal Article

The COVID-19 pandemic has highlighted the importance of rapid, cost effective, accurate, and non-invasive testing for viral infections. Volatile compounds (VCs) have been suggested for several decades as fulfilling these criteria. However currently v... Read More about Breath analysis for detection of viral infection, the current position of the field.

Fenofibrate toxicity and impact on clinical biomarkers in patients with dyslipidaemia (2020)
Thesis

Introduction and aims: Fenofibrate is the most widely used fibric acid derivative for managing mixed dyslipidaemia, characterised by elevated levels of cholesterol, triglycerides and LDL cholesterol and low levels of HDL cholesterol. Fenofibrate is a... Read More about Fenofibrate toxicity and impact on clinical biomarkers in patients with dyslipidaemia.

Density functional theory in the prediction of mutagenicity: A perspective (2020)
Journal Article

As a field, computational toxicology is concerned with using in silico models to predict and understand the origins of toxicity. It is fast, relatively inexpensive, and avoids the ethical conundrum of using animals in scientific experimentation. In t... Read More about Density functional theory in the prediction of mutagenicity: A perspective.

An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy (2020)
Journal Article

SARS-CoV-2 is an emerging β-coronavirus that causes COVID-19 disease that manifests primarily as a pulmonary infection that can rapidly progress into severe and acute respiratory distress in susceptible patients. Initial reports of severe pulmonary i... Read More about An overview of SARS-CoV-2 (COVID-19) infection and the importance of molecular hydrogen as an adjunctive therapy.

Elements of construction: Minecraft and the periodic table (2020)
Report

Minecraft is a popular computer game that allows the construction of almost limitless creations, and is used in learning contexts around the world. The widespread appeal and familiarity of the game makes it ideal for engaging children and young peopl... Read More about Elements of construction: Minecraft and the periodic table.

Targeting the ERG oncogene with splice-switching oligonucleotides as a novel therapeutic strategy in prostate cancer (2020)
Journal Article

Background: The ERG oncogene, a member of the ETS family of transcription factor encoding genes, is a genetic driver of prostate cancer. It is activated through a fusion with the androgen-responsive TMPRSS2 promoter in 50% of cases. There is therefor... Read More about Targeting the ERG oncogene with splice-switching oligonucleotides as a novel therapeutic strategy in prostate cancer.

The visual vaccine debate on Twitter: A social network analysis (2020)
Journal Article

Pro- and anti-vaccination users use social media outlets, such as Twitter, to join conversations about vaccines, disseminate information or misinformation about immunization, and advocate in favour or against vaccinations. These users not only share... Read More about The visual vaccine debate on Twitter: A social network analysis.

Quantitative detection and antibiotic resistance genes characterisation of vibrio species isolated from Asata River in Enugu, South East, Nigeria (2020)
Presentation / Conference Contribution

Investigations into the design and development of novel screenprinted electrochemical biosensors for sugars (2020)
Thesis

The aim of the studies described in this thesis was to develop a set of single shot biosensors, for low concentration measures (less the 1 mM) of glucose, sucrose and fructose. In addition, the development of a user friendly potentiostat instrumental... Read More about Investigations into the design and development of novel screenprinted electrochemical biosensors for sugars.

Report on the Working Practices, Motivations and Challenges of those Engaged in Science Communication (2020)
Report

The working practices of those engaged in the communication of science to non-expert audiences has important implications for the relationship between science and society. The research presented here explores these working practices and the motivatio... Read More about Report on the Working Practices, Motivations and Challenges of those Engaged in Science Communication.

Investigating the Links Between Science Communication Actors and Between Actors and their Audiences (2020)
Report

The audiences reached by those engaged in science communication and the nature of the connections with those audiences is of central importance to the science-society relationship. It determines who is reading, listening and watching information abou... Read More about Investigating the Links Between Science Communication Actors and Between Actors and their Audiences.

Roadmap for naming uncultivated Archaea and Bacteria (2020)
Journal Article

The assembly of single-amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) has led to a surge in genome-based discoveries of members affiliated with Archaea and Bacteria, bringing with it a need to develop guidelines for nomenclature of... Read More about Roadmap for naming uncultivated Archaea and Bacteria.

Workplace Wellbeing - A Relational Approach (2020)
Book

Workplace Wellbeing – A Relational Approach presents the most important, insightful and up-to-date academic thinking and research related to flourishing at work. It describes the transformative humanistic skills, values and attributes ordinarily ado... Read More about Workplace Wellbeing - A Relational Approach.

A long-term monitoring programme for Great Apes in Monte Alén National Park (2020)
Journal Article

BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer (2020)
Journal Article

The cytosolic branched chain aminotransferase (BCATc) protein has been found to be highly expressed in breast cancer subtypes, including triple negative breast cancer (TNBC), compared with normal breast tissue. The catabolism of branched-chain amino... Read More about BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer.