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All Outputs (83)

An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS (2013)
Journal Article

Analysis of volatile organic compounds (VOCs) from saliva, to aid disease diagnoses, has received little attention. This work aims to address the paucity of information on saliva volatiles and includes a database of newly identified compounds whilst... Read More about An investigation of volatile organic compounds from the saliva of healthy individuals using headspace-trap/GC-MS.

Multidimensional model to assess the readiness of Saudi Arabia to implement evidence based child maltreatment prevention programs at a large scale (2013)
Journal Article

There has been increased awareness of child maltreatment in Saudi Arabia recently. This study assessed the readiness for implementing large-scale evidence-based child maltreatment prevention programs in Saudi Arabia. Key informants, who were key deci... Read More about Multidimensional model to assess the readiness of Saudi Arabia to implement evidence based child maltreatment prevention programs at a large scale.

Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling (2013)
Journal Article

Basal forebrain cholinergic neurons (bfCNs) which provide innervation to the hippocampus and cortex, are required for memory and learning, and are primarily affected in Alzheimer's Disease (AD), resulting in related cognitive decline. Therefore gener... Read More about Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling.

Teaching Theory of Mind (2013)
Journal Article

Research Findings: An understanding of another's mental state, beliefs, or desires is often referred to as theory of mind (ToM). Pretence has been shown to be a precursor to ToM (Leslie, 1987; Lillard, 1999, 2001), and thus ToM could potentially be d... Read More about Teaching Theory of Mind.

Effect of breed on fatty acid composition and lipogenic enzyme abundance in the subcutaneous adipose tissue of pigs (2013)
Journal Article

This study investigated the role of lipogenic enzyme expression in breed-specific fat deposition in pigs. Objectives: (i) determine effect of breed on the relative abundance of the key lipogenic enzymes stearoyl-CoA desaturase (SCD), delta-6 desatura... Read More about Effect of breed on fatty acid composition and lipogenic enzyme abundance in the subcutaneous adipose tissue of pigs.

Ecology of reproduction in Sanje mangabeys (Cercocebus sanjei): Dietary strategies and energetic condition during a high fruit period (2013)
Journal Article

The ability to increase energy storage when food is abundant for later use during late gestation and early lactation is often considered the primary benefit of the capital breeding strategy (clustering conceptions during high food periods, HFP) that... Read More about Ecology of reproduction in Sanje mangabeys (Cercocebus sanjei): Dietary strategies and energetic condition during a high fruit period.

Underpotential deposition of lead at silver electrodes manufactured from compact discs and its determination in environmental water samples (2013)
Journal Article

The present paper describes the facile manufacture of silver electrodes from compact discs for the anodic stripping voltammetric determination of lead. The voltammetric behaviour of Pb in 0.1 M HCl was examined by cyclic voltammetry. Using a starting... Read More about Underpotential deposition of lead at silver electrodes manufactured from compact discs and its determination in environmental water samples.

A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace (2013)
Journal Article

There is a need to reduce the number of cystoscopies on patients with haematuria. Presently there are no reliable biomarkers to screen for bladder cancer. In this paper, we evaluate a new simple in-house fabricated, GC-sensor device in the diagnosis... Read More about A Pilot Study Combining a GC-Sensor Device with a Statistical Model for the Identification of Bladder Cancer from Urine Headspace.

Epigallocatechin-3-gallate promotes apoptosis and expression of the caspase 9a splice variant in PC3 prostate cancer cells (2013)
Journal Article

Growing evidence suggests that the flavonoid epigallocatechin-3-gallate (EGCG), notably abundant in green tea, has health-promoting properties. We examined the effect of EGCG on cell survival and apoptosis in the prostate cancer cell line PC3. Cell s... Read More about Epigallocatechin-3-gallate promotes apoptosis and expression of the caspase 9a splice variant in PC3 prostate cancer cells.

Smart integrated biosensor system (2013)
Journal Article

Professor Tony Killard from the University of the West of England is leading a collaborative project to develop and implement smart integrated miniturised sensor systems.

A novel bioluminescent bacterial biosensor for measurement of Ara-CTP and cytarabine potentiation by fludarabine in seven leukaemic cell lines (2013)
Journal Article

This study evaluates an in vitro biosensor assay capable of detecting the intracellular levels of the tri-phosphorylated form of cytarabine (Ara-CTP) within one working day. The biosensor predicted the response of seven leukaemic cell lines with vary... Read More about A novel bioluminescent bacterial biosensor for measurement of Ara-CTP and cytarabine potentiation by fludarabine in seven leukaemic cell lines.